• 제목/요약/키워드: Salivary gland

검색결과 589건 처리시간 0.028초

원발성 폐암의 외과적 고찰 (Surgical Evaluation of Bronchogenic Carcinoma)

  • 박재길
    • Journal of Chest Surgery
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    • 제27권3호
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    • pp.209-214
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    • 1994
  • Lung cancer is one of the most disastrous of all the current cancers in Korea. In 1990 it was projected that there would be 5, 500 new lung cancer patients in Korea and that 5, 000 would die of their disease. This is a mortality rate of 91 percent. We reviewed the surgically treated 153 bronchogenic cancer patients from January 1987 to December 1991 in St. Mary`s Hospital of Catholic University Medical College. There were 121 men and 32 women ranging in age from 18 to 83 years, with a mean of 56 years. Of the 153 patients, resection was possible in 138 patients and the resectability was 90.1 percent. Squamous cell carcinoma was present in 48 percent of patients, adenocarcinoma in 29 percent, adenosquamous carcinoma in 7 percent, large cell carcinoma in 6 percent, salivary gland tumor in 5 percent, and small cell carcinoma and carcinoid in 3 percent respectively. Postoperative cancer staging was grouped stage I 33 percent, stage II 21 percent, stage IIIa 35 percent, and stage IIIb 10 percent. Lobectomy was performed in 70 percent, pneumonectomy in 17 percent, and segmentectomy in 14 percent. Three and 5-year postoperative survival in resectable 138 patients were 47 and 29 percent respectively.

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증식성 근막염의 세침흡인 세포학적 소견 - 1 예 보고- (Fine Needle Aspiration Cytology of Proliferative Fasciitis - A Case Report-)

  • 조향정;한원철;박원철;윤기중
    • 대한세포병리학회지
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    • 제13권1호
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    • pp.47-50
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    • 2002
  • Fine needle aspiration cytology (FNAC) is an easy convenient non-invasive method in the diagnosis of superficial palpable masses. The cytologic findings by FNAC of reactive and neoplastic lesions in various organs including breast, lymph node, thyroid, salivary gland, etc., have been described, but, those of soft tissue lesions including proliferative fasciitis are relatively rare to find. We recently experienced a case of FNAC of proliferative fasciitis in the left back of a 72-year-old male. The FNAC smears were scant in cellularity and contained large cells with abundant basophilic cytoplasm, one to two nuclei lying at the periphery, and prominent nucleoli that resemble ganglion cells.

노화에 따른 위장관 기능의 변화 (Aging and Gasroenterrogi Changes)

  • 조우균
    • 한국식품영양학회지
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    • 제6권3호
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    • pp.219-230
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    • 1993
  • This research aims to study the changes In gastrointestinal function attributed to aging In human. The thresholds for recognition and detection of flavors became elevated and salivary gland acinar cells decreased in the old age. But most esophageal function remained relatively Intact. Although gastric emptying time has been slowed with aging, the total intestinal transit time did not differ. Atropic gastritis due to H. pylori in old man decreased secretion of acid and Intrinsic factor and absorbability of calcium and iron. Pancreatic secretion is droned in older persons. Prevalence of gallstones rised with age. Liver size and portal blood flow decreased significantly with age. Mucosal surface area has been reported to be slightly diminished in the aging man. Glucose transporters decreased and Insulin tolerance Increased. Absorption of aromatic amino acid is diminished with age. Dietary protein In that aging human increased fecal nitrogen excretion. Vitamin A tolerance increased. Vitamin D receptor concentration decreased and resistance to 1,25-(OH)2D3 action increased. Permeability of aging small Intestine Increased. Zinc balance dirt not differ Copper absorption appeared not to be significantly affected by age. Neurotensin secretion decreased thus slowed colonic peristaltic movements and Intestinal mucosal growth.

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둔부에 발생한 골수외 형질세포종 - 증례 보고 - (Extramedullary Plasmacytoma of the Buttock - A Case Report -)

  • 이형석;김정렬
    • 대한골관절종양학회지
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    • 제15권1호
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    • pp.75-80
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    • 2009
  • 골수외 형질세포종은 아주 드물게 발생하는 종양으로, 전체 형질 세포 종양의 3~5 %를 차지하며 상부 호흡기관에서 주로 발생한다. 그 외 드물게 위장관, 방광, 중추 신경계, 유방, 갑상선, 고환, 타액선, 임파선, 피부 등에서 발생한 증례보고가 있다. 저자들은 49세 남자의 대둔근에서 발생한 골수외 형질세포종 1예를 경험하였기에 이를 문헌 고찰과 함께 보고하는 바이다.

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Orocutaneous fistulas of odontogenic origin presenting as a recurrent pyogenic granuloma

  • Lee, Jin Hoon;Oh, Jae Wook;Yoon, Sung Ho
    • 대한두개안면성형외과학회지
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    • 제20권1호
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    • pp.51-54
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    • 2019
  • Orocutaneous fistulas, or cutaneous sinuses of odontogenic origin, are uncommon but often misdiagnosed as skin lesions unrelated to dental origin by physicians. Accurate diagnosis and use of correct investigative modalities are important because orocutaneous fistulas are easily confused for skin or bone tumors, osteomyelitis, infected cysts, salivary gland fistulas, and other pathologies. The aim of this study is to present our experience with a patient with orocutaneous fistulas of odontogenic origin presenting as recurrent pyogenic granuloma of the cheek, and to discuss their successful treatment.

Current concepts of Kimura disease: pathophysiology and evolution of treatment

  • Woo Ju, Kim;Han Koo, Kim
    • 대한두개안면성형외과학회지
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    • 제23권6호
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    • pp.249-255
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    • 2022
  • Kimura disease (KD) is a chronic inflammatory disorder that frequently involves the subcutaneous tissue of the head and neck regions. It often manifests as regional lymphadenopathy or salivary gland enlargement in the affected area. The histologic architecture of the lymph nodes in KD patients is preserved, while the affected tissues show follicular hyperplasia and eosinophilic infiltration. No single modality has been adopted as an optimal treatment for KD. This article concentrates on the fundamental features of KD and reviews current approaches to its treatment.

Buccal nerve schwannoma mimicking a salivary gland tumor: a rare case report

  • Jeong-Kui Ku;Dawool Han;Jong-Ki Huh;Jae-Young Kim
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • 제49권3호
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    • pp.148-151
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    • 2023
  • Schwannomas are benign tumors originating from myelinating cells constituting nerve sheaths but rarely contain cellular elements of the nerve. The authors encountered a 47-year-old female patient with a schwannoma on the anterior mandibular ramus arising from the buccal nerve, measuring 3 cm×4 cm. Surgical resection was performed with preservation of the buccal nerve via microsurgical dissection. After one month, the sensory function of the buccal nerve was recovered without complications.

구속 스트레스에 의한 타액선 조직내의 Clusterin 발현 (Expression of Clusterin in the Salivary Gland under Restraint Stress)

  • 박희경;전양현;홍정표;어규식
    • Journal of Oral Medicine and Pain
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    • 제33권3호
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    • pp.247-256
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    • 2008
  • 일상생활에서 우리는 항상 스트레스에 노출되어 있으며, 스트레스에 대한 반응은 우리 삶의 질과 건강에 중요한 영향을 미친다. 특히 정서적으로 중요한 구강안면영역에도 다양한 스트레스성 질환이 존재한다. 그러나 스트레스와 질병에 관한 오랜 연구에도 불구하고 스트레스성 구강안면질환의 병인은 아직 명확하지 않다. 이에 저자는 최근 임상의학에서 관심이 집중되어지고 있는 스트레스와 질병에 대한 분자생물학적 접근의 일환으로 스트레스성 구강안면질환의 병인을 규명하고자 본 연구에 임하였다. 즉, 스트레스 단백질로 알려진 clusterin이 스트레스의 생리적 반응으로서 세포보호작용 결과 발현된다는 사실에 기초하여, 스트레스 부여 후 타액선 조직 내에서의 그 발현변화를 추적하였다. Sprague-Dawley계 웅성 백서(200-230g/bw)를 구속 스트레스 부여군(구속장치에 구속한 후 0, 3, 5일에 희생) 및 정상군으로 나누고, 각각 악하선을 적출하였으며, 면역조직화학법 및 Northern Blot을 이용하여 Clusterin의 변화를 관찰하였다. 그 결과는 다음과 같다. 1. 구속 스트레스 부여군의 clusterin 단백질은 실험 즉일군에서 증가되었고, 그 이후에는 감소되었다. 2. 구속 스트레스 부여 3일군과 5일군에서 핵붕괴 및 핵농축 등의 핵변화를 동반한 apoptosis가 유도되었다. 3. 구속 스트레스 부여 결과, 선포세포가 도관세포보다 일찍 세포사하였다. 4. 구속 스트레스 부여군의 clusterin mRNA는 실험 즉일군에서만 미약하게 관찰되었다. 즉, 타액선 조직은 스트레스 단백질인 clusterin을 생산하여 세포를 보호함으로써 스트레스 상황에 적응하지만, 생리적 적응한계를 넘는 스트레스에 노출될 때에는 조직이 apoptosis됨이 확인되었다. 따라서, 본 연구결과는 구강건조증등 스트레스성 타액선관련 증상 및 질환의 병리적 기전에 대한 규명에 도움이 되리라고 생각하며, 또한 clusterin은 향후 생체에 가해진 스트레스에 대한 표식자(marker)로 사용될 수 있을 것으로 사료된다.

기관지 선종의 외과적 치료[17례 보고] (Surgical Treatment of Bronchial Adenoma - Reports of 17 Cases -)

  • 문석환
    • Journal of Chest Surgery
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    • 제25권3호
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    • pp.247-257
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    • 1992
  • Bronchial adenoma, firstly described by Muller[1882] had been reported on the subject stressed their benign nature prior to 1940`s, but these tumors including carcinoid tumor, mucoepidermoid carcinoma, adenoid cystic carcinoma, pleomorphic adenoma are now known to possess the various degree of malignant natures from benign course, low grade malignant potential to distant lymphatic or hematogenous metastasis or combination. Although histologically diffeerent, four varieties except carcinoid tumor which is a spectrum of neu-roendocrine tumor originating Kulchitsky cell of the bronchial epithelium and form the part of the APUD tumor spectrum, are morphologically and in many respects clinically similar to the corresponding tumor of the salivary gland is a specific varient of adenocarcinoma that occurs most commonly in the major and minor salivary gland and less frequently tra-cheobronchial tree, esophagus etc. To better understand the clinical characteristics and assess more precisely the malignat nature of bronchial adenoma, we studied 17 cases of bronchial adenoma, which had been experienced at the Department of Thoracic and Cardiovascular surgery of Catholic University Medical College from April 1977 to september 1991. Seventeen cases of bronchial adenoma consist of 2 carcinoid tumors, 6 adenoid cystic carcinomas, 8 mucoepidermoid carcinomas and one pleomorphic adenoma. There is a slight predominace of male patients[10/17] and the age of pt studied varied with a higher incidence occurring between the ages of 40 years and 60 years[mean age, 46.5 years]; the youngest being 15 years and oldest 69 years. Their leading complaints were hemoptysis[4], exertional dyspnea[8], fever & chilness [4], and symptoms mimicking the bronchial asthma[4]. Diagnosis was aided by the radiologic studies such as chest X-ray, polytomography, CT scan, brochography and bronchoscopy. The preferred locations of fumor were in the trachea[4], main stem bronchus[3], bronchus intermedius[3], bronchus of RUL[2], LUL[1], RLL[1], LLL[3] with no peripheral location. Modalities of treatments were single or combination of surgical resection, radiation therapy, chemotherapy. Complete resections were permitted in 12 cases with late recurrences of 4 cases ranging from 6 months to 10 years: pneumonectomy[4], lobectomy[4], bil-obectomy[2], sleeve resection[2]. Gross findings of resected specimens in 14 cases showed that 4 cases were polyp-like pedunculated mass[entirely intraluminal mass] with intact mucosa, 8 cases were broad-bas-ed sessile mass[predominatly intraluminal] and the main portions were located below the mucosa similar to tip of iceburg[predominantly extraluminal] in 2 cases. Follow-up information was availble in all 17 cases ; eight were alive without evidence of disese ranging from 1 month to 13 years. But seven cases died of the causes related to tumor[6 cases within 12 months, one case 10 years after pneumonectomy]. We concluded that 8 cases[47%] of 17 cases were metastasizing bronchial adenoma and precise survival rate cannot be answered by the scanty materials available for study.

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Relative Frequency of Oral Malignancies and Oral Precancer in the Biopsy Service of Jazan Province, 2009-2014

  • Idris, AM;Vani, NV;Saleh, Sanna;Tubaigy, Faisal;Alharbi, Fahd;Sharwani, Abubkr;Tadrus, Nabil;Warnakulasuriya, Saman
    • Asian Pacific Journal of Cancer Prevention
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    • 제17권2호
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    • pp.519-525
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    • 2016
  • Background: The objective of this study was to report the types and relative frequency of oral malignancies and precancer in the Jazan region of Saudi Arabia during the period 2009-2014. Materials and Methods: Pathology reports were retrieved from the archives of Histopathology Department, King Fahd hospital in Jazan. Demographic data on tobacco habits, clinical presentation and histologic grading of oral precancer and cancer cases were transcribed from the files. Results: 303 (42.7%) oral pre-malignant and malignant cases were found out of 714 oral biopsy lesions. A pathology diagnosis of squamous cell carcinoma (85.1%) was most frequent, followed by premalignant lesions/epithelial dysplasia (8.6%), verrucous carcinoma (3.3%) and malignancy of other histological types (3%) such as ameloblastic carcinoma, salivary gland malignancy and sarcomas. Oral squamous cell carcinoma was predominant in females with a male to female ratio of 1:1.9. Patient age ranged from 22 to 100 years with a mean of $65{\pm}13.9$. Almost 44.6% of oral cancer had occurred after 65 years of age. Only 16.3% cases were reported in patients younger than 50 years, predominantly females. The majority of female patients had the habit of using shammah with a long duration of usage for more than 45 years. Buccoalveolar mucosa (52.3%) was the common site of involvement followed by tongue/floor of the mouth (47.7%) and clinically presented mostly as ulceration/swelling clinically. Moderately differentiated tumours (53.9%) were common followed by well differentiated (32.2%) and poorly differentiated tumours (5.8%). The prevalence of oral verrucous carcinoma (3.3%) was comparatively low with an equal distribution in both males and females. Both bucco-alveolar mucosa and tongue were predominantly affected. Oral precancer/epithelial dysplasia (8.6%) was common in females with a shammah habit. Bucco-alveolar mucosa was commonly involved and clinically presented mostly as white/red patches. Most cases were mild followed by moderate and severe dysplasia. Tumours of other histological types (3%) include 1 ameloblastic carcinoma, 3 malignant salivary gland tumours and 5 sarcomas. Conclusions: In this study, it was found that oral cancers reported in the pathology service to be a common occurrence. This study reconfirms previous reports of the high burden of oral cancer in this population This indicates that conventional preventive programs focused on oral cancer are in need of revision. In addition, further research into identifying new risk factors and molecular markers for oral cancer are needed for screening high risk individuals.