• 핵의학기술
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• 제13권1호
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• pp.15-19
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• 2009

Purpose: The aim of study is to find a correlation between Salivary clearance rate using saliva and blood and Secretion rate and Excretion rate using Salivary gland Scan images. Materials and Methods: Salivary Scan and Stimulate clearance of $^{99m}Tc$-pertechnate was performed in 20 patients with moderate function(group 1), 9 patients with severe function glands (group 2), 3 patients with non function (group 3) and normal 6 controls. Salivay clearance rate was compare with Secretion rate and Excretion rate of Salivary glands' ROI. Result: Stimulate salivary clearance of normal controls was 18.4 ml/min, salivary clearance of group 1 was 10.1 ml/min, salivary clearance of group 2 was 10.4 ml/min and salivary clearance of group 3 was 2.3 ml/min. Significant difference was found between normal controls and group 2,3 (p<0.05, p<0.05). Secretion rate and Excretion rate of normal controls was 21.6%, 24.6%, Secretion rate and Excretion rate of group 1 was 17.6%, 24.0%, Secretion rate and Excretion rate of group 2 was 8.8%, 13.9% and Secretion rate and Excretion rate of group 3 was 5.6%, 2.9%. Significant difference was found between normal controls and group 2,3 (p<0.05, p<0.05). Conclusions: Stimulate salivary clearance using saliva and blood and Secretion rate and Excretion rate using Salivary gland Scan images accord well together.

• Journal of Oral Medicine and Pain
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• 제23권3호
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• pp.235-239
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• 1998

In Sjogren syndrome, abruptly decreased salivation and delayed lag time reveal that many acini cells are destructed and Lymphocytes infiltration is supposed as the main cause that makes dysfunction of salivation. In this case report, the biopsy of minor salivary glands is very useful diagnostic method of Sjogren's syndrome with sialometry,sialography, salivary gland scan.

• 대한핵의학회지
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• 제21권2호
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• pp.151-154
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• 1987

Total 114 patients were studied prospectively with radioiodine uptake (RAIU) and $^{99m}TcO_4^-$ thyroid scan to design a very simple, rapid and inexpensive method measuring the thyroid uptake on thyroid scan. After the RAIU was obtained at 24 hours after P.O. of $^{131}I$, Thyroid scan was performed at 20 minutes after LV. of $^{99m}TcO_4^-$ and the bilateral salivary glands were included in the scan field. Pinhole collimated and computer assisted gamma camera was used. Three regions of interest were set on each salivary gland and on the thyroid by automatic edge detection method. Mean counts per pixel were calculated for each ROI and the salivary-thyroid ratio (STR) was defined as; $$STR(%)=\frac{Mean\;counts\;per\;pixel\;of\;salivary\;glands\;(KC)}{Mean\;counts\;per\;pixel\;of\;thyroid\;gland\;(KC)}\times100$$ 114 cases consisted of 41 normal, 55 hyperthyroid and 18 hypothyroid patients and correlation between the STR and the RAID were evaluated in total and each group. The STR and the RAID showed reverse linear regression in 114 cases (r= -0.8, P=0) and closer correlation was shown in hyperthyroid group (r= -0_9, p=0). Mean STR in normal group was 47.6%. In predicting the RAID by STR, sensitivity and specificity were 88.3% and 64.9% in 114 cases and 95.3% and 83.3% in hyperthyroid group. It is recommended that the STR be used in place of the RAID giving same information at saving time, money and radiation exposure.

• 치과방사선
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• 제25권1호
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• pp.27-38
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• 1995

The organ or tissue doses were determined with head and neck phantom measurement for multiple axial scans (36 slices), multiple coronal scans (13 slices), 3 types of single axial scans(orbit, maxillary sinus and mandibular canal) and single coronal scan (maxillary sinus). For each scan sequence 30 TLDs were placed in selected sites(16 internal sites and 14 external sites) in a tissue-equivalent phantom. The exposure was made at 120kVp, 500mAs with 5 mm slice width. The results were as follows : 1. In multiple axial scans, the greatest effective dose recorded was that delivered to the thyroid glands(2.77 mSv) and the least was that received by the skin(0.05 mSv). From these data, stochastic effects were 202.2x10/sup -6/ and 3.7×10/sup -6/, respectively. 2. In multiple coronal scans, the greatest effective dose recorded was that delivered to the salivary glands(0.58 mSv) and the least was that received by the skin(0.01 mSv). From these data, stochastic effects were 42.2×10/sup -6/ and 0.7×10/sup -6/, repectively. 3. Among single axial scans, the greatest effective dose recorded was that delivered to the salivary gland(0.38 mSv) in maxillary sinus scan. From this data, stochastic effect was 27.7×10/sup -6/. 4. In single coronal scan, the greatest effective dose recorded was that delivered to the salivary gland(0.01 mSv). From this data, stochastic effect was 1.0×10/sup -6/. 5. The equivalent dose measured that delivered to the lens of the eyes was 69.64 mSv in multiple axial scan, 39.32 mSv in multiple coronal scan and 36.77 mSv in single axial scan(orbit).

• 한국방사선학회논문지
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• 제9권6호
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• pp.357-362
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• 2015

테크네슘을 이용한 침샘검사의 시간-방사능 곡선에서 다양한 기능매개변수지표를 획득하여 환자 군과 건강한 정상군과의 비교를 통해 유용성을 알아보고자 하였다. 2014년 12월부터 2015년 2월까지 구강 건조증으로 침샘검사를 시행한 환자군 30명과 건강한 정상군 10명을 대상으로 하였다. 99mTc-과산화테크네슘 370 MBq을 정맥으로 주사 후 20분에 비타민C 파우더를 입안에 투여하여 10분 동안 촬영하였다. 분석방법은 귀밑샘과 턱밑샘의 관심영역을 정하여 시간-방사능 곡선을 그린 후 곡선의 각 위치에서 다양한 기능매개변수 지표를 획득하고, 구강 건조증 환자군와 정상군을 비교하였다. 비교 및 측정에 적용된 방법으로는 섭취율(uptake ratio, UR), 최대 방사능 시간(time at maximum counts, Tmax), 최소 방사능 시간(time at minimum counts, Tmin), 최대 축적율(maximum accumulation, MA), 축적 속도(accumulation velocity), 최대 배출율(maximum secretion, MS), 최대 자극 배출율(maximum stimulation secretion, MSS), 배출속도(secretion velocity, SV)를 사용하였다. 환자군과 정상군간의 기능매개변수지표 비교에서 환자군의 최소 방사능 시간(Tmin)을 제외한 모든 지표에서 건강한 정상군이 환자군에 비하여 유의한 차이를 보였고, 시간에 따른 변화량에서도 정상군이 환자군에 비하여 유의한 차이를 보였다. 결론적으로 침샘검사에서 다양한 기능매개변수지표를 이용한 정량분석은 구강 건조증 환자의 침샘 기능을 객관적이고 표준화된 정보로 평가하는데 유용할 것으로 사료된다.

• Imaging Science in Dentistry
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• 제30권2호
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• pp.144-148
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• 2000

Sjogren's syndrome is a chronic inflammatory disease that predominantly affects salivary, lacrimal and other exocrine glands. We report a case of Sjogren's syndrome combined with MALT (mucose associated lymphoid tissue) lymphoma which occured in the parotid gland. A 57-year-old female with the complaint of painful swelling and lymph node enlargement was referred to our department. Sialograms of both parotid glands showed globular collections of contrast material uniformly distributed throughout the parotid gland. Salivary scintigraphy showed decreased uptake of the parotid gland. CT scan showed larger, slightly more dense parotid gland than normal and honeycomb glandular appearance. Also, It showed discrete, slightly more enhanced round mass in the left parotid gland. Histopathological finding showed replacement of salivary gland parenchyma with dense small lymphocytic infiltration having the feature of epimyoepithelial islands. Kappa light chain restriction of interglandular plasma cell could be seen.

• 대한두경부종양학회지
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• 제24권2호
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• pp.207-210
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• 2008

The purpose of this paper is to review our experience with mucoepidermoid carcinoma(MEC), a rare tumour in minor salivary glands, in a paediatric patients. 15-year-old boy was noted to have a irregular round mass appearing atthe soft palate just to the right of the mid-line. A computed tomographic(CT) scan showed a palatal mass limited to soft palate with no bony erosion. The lesion was curetted and debulked. Pathology was reported as an intermediate-grade mucoepidermoid carcinoma, and the patient was considered to radiation therapy institution for further treatment. To date, patients remain free of disease. Wide local excision is the treatment of choice for low to intermediate grade MEC of the minor salivary glands in paediatric patients.

• Nuclear Medicine and Molecular Imaging
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• 제43권2호
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• pp.154-155
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• 2009

A 45-year-old man presented with fatigue and weight loss underwent a Tc-99m MDP bone scan because of increased serum alkaline phosphatase. Delayed images at 4 hours demonstrated diffuse increased activity throughout both lobes of the thyroid in the absence of activity of the stomach and salivary glands. Thyroid laboratory indices and a Tc-99m pertechnetate thyroid scan suggested Graves' hyperthyroidism.

• 대한두경부종양학회지
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• 제13권2호
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• pp.269-274
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• 1997

Parotid canalicular adenoma is a benign neoplasm that is predominantly composed of branching and interconnecting cords of single or double rows of columnar epithelium in a very loose stroma. There has been considerable confusion in the literature concerning the terminology of canalicular adenoma. However, thesedays it has been newly-recognized as a discrete entity of the monomorphic adenoma group. Canalicular adenoma has a remarkable predilection for occurrence in the minor salivary glands such as the upper lip, in contrast with basal cell adenoma that occurs predominantly in major salivary glands such as the parotid gland. We have experienced a case of canalicular adenoma of the parotid gland in a 65-year-old woman. The patient had a palpable mass on the preauricular area for the last 15 years and recently noticed a mild pain and discomfort on the mass. Neck ultrasonography showed a low echogenic mass of 1.0cm in diameter in the right parotid gland and a neck CT scan showed a well-enhanced rectangular-shaped mass. A superficial parotidectomy was performed for the lesion and the final pathologic diagnosis turned out to be 'multifocal canalicular adenoma'.

• 대한핵의학회지
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• 제39권6호
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• pp.489-490
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• 2005

Purpose: The thyroglossal duct runs from the base of the tongue to the thyroid. Rarely the thyroid completely fails to migrate and results in ectopic thyroid tissue, which can be demonstrated scintigraphically. A 31-year old female patient was referred for thyroid scintigraphy due to protruding mass at the base of the tongue. She was mildly hypothyroid. Te-99m pertechnetate thyroid scan was performed to rule out ectopic thyroid gland. There showed a focal area of intense tracer uptake in sublingual area, suggesting the sublingual thyroid. In addition there noted diffusely increased tracer uptake in both breasts. The patient delivered a baby 6 months prior to the scan and was on breast-feeding. Free Tc-99m pertechnetate physiologically secrets into the salivary glands, the stomach, the gastrointestinal tract, the genitourinary tract and the mammary glands and sodium-iodide symporter plays a role in the accumulation of free Tc-99m pertechnetate. We report simultaneous visualization of lactating breasts and ectopic thyroid gland in the base of the tongue.