• 대한중풍순환신경학회지
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• 제12권1호
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• pp.1-7
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• 2011

Objectives : The purpose is to discuss the clinical applications of Orungsan(Goreisan: 五苓散) as an alternative management for increased intracranial pressure in the field of neurosurgery in Japan. Methods and Results : Attention has focused on Kampo medicine(traditional Japanese medicine) for some cerebral disease including chronic subdural hematoma(CSDH) and cerebral infarction in Japan. Orungsan and one of its classes, Sirungtang(Saireto: 柴苓湯) are well known their effects on brain edema. After some studies of Orungsan has the anti-edemic effects by the inhibition of aquaporin, this herbal medicine has been used widely in the neurosurgery field in Japan. It is high time to think about where we are and we go ahead for the progress and the integration in medicine. We have reviewed the studies using Orungsan or Sirungtang, that was reported at the 20th annual meeting of 'the Japan society for Kampo medicine and neurological surgery' was held on November 5, 2011 in Tokyo. Fifteen studies related with Orungsan or Sirungtang were reported among all 32 studies at the meeting. Orungsan in ten, and Sirungtang in five among 14 studies contained specific clinical case. In the aspects of disease, thirteen papers were related with SDH, including CSDH(11), SSDH(1), aneurism clipping for SDH prevention(1), and one was acute cerebral infarction and one was multiple metastatic brain tumor. In the report style, case control study was 7(mostly retrospective), and the case report was 8. Conclusions : Orungsan may be plausible to be an alternative method to reduce brain edema after SDH and other brain injury in the field of neurosurgery.

• 대한중풍순환신경학회지
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• 제14권1호
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• pp.107-114
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• 2013

■ Objectives The purpose is to review the application of the Kampo medicine(traditional Japanese medicine) in the neurosurgical field, through the analysis of the studies are presented at the Annual Meeting of Kampo Medicine Association of the Japan Neurosurgical Society. ■ Methods We have reviewed the studies that were reported at the 21th annual meeting of the Kampo medicine association of the Japan neurosurgical society was held on November 3 2012 in Tokyo, Japan. Seventeen included clinical reports were analyzed among all 25 studies at the meeting. Five studies were related with headache and eight were focused on the cerebrovascular disease including chronic subdural hemorrhage(CSDH) treated with Orungsan(Goreisan: 五苓散) or Siryungtang(Saireto: 柴苓湯), and other four were for pain managements. In the matters of headache, a unique feature was that Osuyutang(Gosyuyuto: 吳茱萸湯) or Oryungsan was considered as the first choice of the treatment for the headache, unlike Korea. It seems to consider to application the treatment of CSDH using Oryungsan in neurosurgery field of Korea. In addition, herbal prescription using Jackyakgamchotang(Syakuya kukanzoto: 芍藥甘草湯), Ukgansan(Yokkansan: 抑肝散), Chitabakilbang(Jidabokuippo: 治打撲一方) for acute/chronic pain is as well one of the peculiar points of Kampo medicine in Japan. ■ Conclusion It is expected that the recent studies performed in Japan neurosurgery fields to inspire domestic research and clinical applications, and needed to additional research and utilize in practice in Korea.