• Proceedings of the Korean Society of Medical Physics Conference
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• 2002.09a
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• pp.328-330
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• 2002

Large balloon angio catheter is used for Percutaneous Transluminal Angioplsty(TPA) of the iliac, femoral and renal arteries as well as after Transjugular Intrahepatic portosystemic shunt(TIPS). The use of angioplasty balloon filled with liquid form of radioisotope reduces the rate of restenosis after PTA. The purpose of this study was to evaluate the absorbed dose to the target vessels from various sized large balloon filled with liquid form of Ho-166-DTPA. Four balloons of balloon dilatation catheters evaluated were 5, 6, 8 and 10 mm in diameter. GafChromic film was used for the estimation of the absorbed dose near the surface of the balloon catheters. Absorbed dose rates are plotted in units of Gy/min/GBq/ml as a function of radial distance in mm from the surface of balloon. The absorbed dose rate was 1.1, 1.6, 2.2 and 2.3 Gy/min/GBq/ml at a balloon surface, 0.3, 0.4, 0.5 and 0.6 Gy/min/GBq/ml at 1 mm depth for various balloon diameter 5, 6, 8 and 10 mm in diameter respectively. The study was conducted to estimate the absorbed doses to the vessels from various sized large balloons filled with liquid form of Ho-166-DTPA for clinical trial of radiation therapy after the PTA. The absorbed dose distribution of Ho-166 appeared to be nearly ideal for vascular irradiation since beta range is very short avoiding unnecessary radiation to surrounding normal tissues.

• 한국지구물리탐사학회:학술대회논문집
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• 2006.06a
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• pp.61-70
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• 2006

3-D S-wave velocity model in the southern Korean Peninsula is investigated by using the joint inversion of receiver functions and surface-wave dispersion. A peninsula average Rayleigh-wave phase velocity in the 10-150 seconds range and tomographic estimates of the Rayleigh and Love wave group velocities in the 0.5-20 seconds period range determined using a $12.5{\times}12.5\;km$ grid for the southern part of the peninsula are used for the inversion. Receiver functions were determined from broadband (STS-2), short-period (SS-1) and acceleration (Episensor) channels of 95 stations. The dense distribution of the stations in the Peninsula permits us to examine the 3-D crustal structure in detail. The inversion result shows the variation and characteristics of S-wave velocity in the crust and upper mantle of the southern Korean Peninsula very well.

• 한국지구물리탐사학회:학술대회논문집
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• 2006.06a
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• pp.41-50
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• 2006

The crustal structure of Korean Peninsula have been investigated by analyzing group velocity dispersion data of surface wave. Cross.correlation of seismic background motions (Campillo and Paul, 2003; Shapiro et al., 2005) has been applied to estimate the short.period Rayleigh. and Love.wave group velocity dispersion characteristics of the region. Standard processing procedures were applied to the cross.correlation, except that signal whitening was used in place of one.bit sampling equalize power in signals from different times. Multiple.filter analysis was used to extract the group velocities from the estimate Green's functions, which were then use to image the spatially varying dispersion at periods between 0.5 and 20 seconds. The tomographic inversion technique used inverted all periods simultaneously to provide a smooth dispersion curve as a function of period in addition to the usual smooth spatial image for a given period. The Gyeongsang Basin in the southeastern part of the peninsula is clearly resolved with lower group velocities.

• Therapeutic Science for Rehabilitation
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• v.1 no.1
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• pp.39-56
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• 2012

Introduction : Animal studies cannot be applied directly to Occupational Therapy(OT) intervention protocol. However, animal models still provide essential evidences and knowledge to improve OT practice and to develop OT theories as well as human studies do. The purpose of this scholarly paper is to explore the potential of animal models to inform OT theory and practice particularly as it relates to neuroscience. Body : The animal models provide related knowledge for a better understanding of the mechanism of diseases and related neural networks. Based on this knowledge, researchers can test their hypothesis of neural disease. In addition, accumulated animal studies contribute to introduce the new approaches to human diseases and to improve the effectiveness of treatment. Conclusions : Animal models of neurological disease are critical and have the potential to improve OT practice and theory in many ways. Therefore, OT researchers need to pay more attention to animal models in addition human studies.

• Research in Community and Public Health Nursing
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• v.15 no.2
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• pp.298-307
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• 2004

Purpose: This study purposed to investigate the relationship between soldiers' general characteristic and their knowledge, attitude and health-belief about AIDS. Method: This study conducted a survey of 197 soldiers using a structured questionnaire. Data were collected from the 10th to 30th of May 2003. Result: The average age of the participants was 21.6 years, 78.2% of them were undergraduates of universities, and by religion the number of Christians was largest. In addition, 81.2% of them had lived with their parents and siblings before they joined the army and most of them were unmarried. Of the subjects, 75.1% finished education about AIDS, 64.5% experienced a sexual intercourse and 6.3% experienced a venereal disease. The participants' knowledge level about AIDS was 14.6 out of 20 points and their attitude about AIDS is 3.96 out of 5 points on the average. Their health-belief about AIDS was 4.0 out of 5 points in 'perceived benefits,' 2.9 in 'perceived barriers,' 2.6 in 'perceived seriousness' and 2.6 in 'perceived sensitivity. Among the subjects' general characteristics, religion was found to be a statistically significant variable for their knowledge level about AIDS. A variable that is statistically significant for the subjects' attitude toward AIDS was families they had lived together before joining the army. Statistically significant variables for the subjects' health-belief about AIDS were perceived sensitivity and experience in venereal diseases, perceived benefits and AIDS education and perceived barriers and marital status. The subjects' knowledge about AIDS was in a statistically significant correlation with their attitude toward AIDS, and their attitude toward AIDS with perceived benefits. Conclusion: According to the results of this study. those who had had AIDS education appeared to have high attitude and health-belief concerning AIDS. Thus it is necessary to execute AIDS education systematically and continuously in order to have right attitude and high health-belief concerning AIDS.

• Korea Journal of Hospital Management
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• v.3 no.1
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• pp.83-99
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• 1998

The purpose of this study is to investigate factors influencing the attitude and satisfaction with inventory management of hospitals. Data were collected from 344 employees in two hospitals located in Seoul and one hospital located in Choong-Chung Do, Korea, using a self-administered questionnaire. Items included in the self-administered questionnaire were hospital and socioeconomic characteristics of personnels such as the level of knowledge, practice, attitude, and satisfaction with inventory management of hospitals. Major findings were as follows; Job position was significantly associated with satisfaction with inventory management. According to age, sex, type of position and aptitude of personnel the level of positive attitude to and satisfaction with inventory management showed significant association. Generally, those who had higher level of knowledge and practice showed a higher tendency toward positive attitude of inventory management, except for those in medical support post. A higher tendency of satisfaction with inventory management was also observed, with the exception of personnel in nurse post. This study showed that major factors affecting attitude toward inventory management are level of knowledge and practice, and factors affecting satisfaction are job position and aptitude. The level of attitude and satisfaction explained by these factors were 46.8% and 12.2%, respectively. According to the results of this study, higher level of knowledge and practice, job position and aptitude appear to be essential for the implementation of effective inventory management. Factors affecting attitude and satisfaction of inventory management should be studied more in depth systematically so that other objective test and measurements can be developed.

• Particle and aerosol research
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• v.5 no.2
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• pp.37-43
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• 2009

Particulate matter (PM) is one of the major indoor air pollutants especially in the subway station in Korea. In order to remove PM in the subway station, several kinds of PM removal system such as roll-filter, auto-washable air filter, demister, and electrostatic precipitator are used in the air handling unit (AHU) of subway stations. However, those systems are prone to operation and maintenance problems since the filter-regeneration unit consisting of electrical or water jet parts might malfunction due to the high load of particulates unless the filter medium is periodically replaced. In this study, the use of axial-flow cyclone was proposed for particulate filter unit in the AHU for its low operation and maintenance cost. Novel shape of axial-flow cyclone was designed by using computational fluid dynamics (CFD). The shape of vortex vane was optimized in terms of pressure drop and tangential velocity. In addition, CFD analysis was validated experimentally through the pressure drop measurement of mock-up model. We found that pressure drop and tangential velocity of fluid through the axia-flow cyclone was significantly affected by the rotating degree of vortex vane and the numerical prediction of pressure drop agreed well with experimental measurement.

• BMB Reports
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• v.41 no.2
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• pp.153-157
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• 2008

The objective of the present study was to identify mitochondrial components associated with the damage caused by iron to the rat heart. Decreased cell viability was assessed by increased presence of lactate dehydrogenase (LDH) in serum. To assess the functional integrity of mitochondria, Reactive Oxygen Species (ROS), the Respiratory Control Ratio (RCR), ATP and chelatable iron content were measured in the heart. Chelatable iron increased 15-fold in the mitochondria and ROS increased by 59%. Deterioration of mitochondrial function in the presence of iron was demonstrated by low RCR (46% decrease) and low ATP content (96% decrease). Using two dimensional gel electrophoresis (2DE), we identified alterations in 21 mitochondrial proteins triggered by iron overload. Significantly, expression of the $\alpha$, $\beta$, and d subunits of $F_1F_o$ ATP synthase increased along with the loss of ATP. This suggests that the $F_1F_o$ ATP synthase participates in iron metabolism.

• Journal of Korean Neurosurgical Society
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• v.54 no.1
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• pp.30-33
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• 2013

Objective : To suggest a new useful diagnostic technique, principles of the selective excitation technique-magnetic resonance images (Proset-MRI), and to know the precise radiologic findings that can prove symptomatic foraminal and extraforaminal stenosis at L5-S1. Methods : Nineteen patients with symptomatic L5-S1 stenosis were checked by Proset-MRI. Four patients were performed decompressive surgery and 15 patients were performed selective nerve root block (SNRB) at L5. The pain scale of patients was checked by Visual Analogue Scale (VAS) scores at the pre- and post-treatment state. Results : Proset-MRI findings of patients with symptomatic stenosis are root swelling (RS) and indentation. The comparisons with VAS scores had a meaningful statistical result at each RS (p<0.01) and indentation (p<0.01). However, the findings of RS combined with indentation lacked statistical significance (p=0.0249). In addition, according to a comparison with the treatment modalities, reducing of VAS scores had statistical meaningful significance in decompressive surgery cases (p<0.01), and also in SNRB cases (p<0.01) after a 3-month follow-up period. Conclusion : The three dimensional Proset-MRI is very useful and sensitive technique to diagnose the symptomatic foraminal and extraforaminal stenosis at L5-S1.

• Journal of Korean Neurosurgical Society
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• v.60 no.2
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• pp.138-145
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• 2017

Objective : High frequency stimulation (HFS) of the subthalamic nucleus (STN) is recognized as an effective treatment of advanced Parkinson's disease. However, the neurochemical basis of its effects remains unknown. The aim of this study is to investigate the effects of STN HFS in intact and 6-hydroxydopamine (6-OHDA)-lesioned hemiparkinsonian rat model on changes of principal neurotransmitters, glutamate, and gamma-aminobutyric acid (GABA) in the striatum. Methods : The authors examined extracellular glutamate and GABA change in the striatum on sham group, 6-OHDA group, and 6-OHDA plus deep brain stimulation (DBS) group using microdialysis methods. Results : High-pressure liquid chromatography was used to quantify glutamate and GABA. The results show that HFS-STN induces a significant increase of extracellular glutamate and GABA in the striatum of 6-OHDA plus DBS group compared with sham and 6-OHDA group. Conclusion : Therefore, the clinical results of STN-HFS are not restricted to the direct STN targets but involve widespread adaptive changes within the basal ganglia.