Ha, Kwang-Soo;Yoo, Hyun-Duk;Shim, Kil-Bo;Kim, Ji-Hoe;Lee, Tae-Seek;Kim, Poong-Ho;Ju, Ja-Yeon;Lee, Hee-Jung
Korean Journal of Fisheries and Aquatic Sciences
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v.44
no.6
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pp.612-621
/
2011
The influences of inland pollution sources because of rainfall events on the bacteriological water quality in Geoje Bay, a major shellfish production area in Korea, were investigated. The sanitary status of sea water and shellfish after rainfall events was also evaluated. The flow rates of 13 streams around Geoje Bay showed 6 to 7-fold increases after 15 to 21 mm of rainfall. Peak pollution was observed in the Naegan Stream, the Gandeok Stream and the Seojeong Stream. The calculated impact area of inland pollution sources was 3.1 $km^2$ immediately after 15 mm of rainfall and expanded to 3.5 $km^2$ after 24 hours. These calculations of impacted area matched results from fecal coliform analyses with sea water. The distance between the major pollution source in the bay (the Gandeok Stream) and the station with the worst bacteriological water quality immediately after 15 mm of rainfall, which was below the Korean standard, was 0.8 km in a straight line; this distance increased to 2.0 km after a period of 24 hours. The area impacted by inland pollution sources after a 15 mm rainfall event was wider than after a 21 mm rainfall. Although the flow rate from inland pollution sources was higher, the concentration of fecal coliform in the discharged water was lower after higher rainfall events. These observations corresponded with the results of fecal coliform analyses with sea water samples. According to the evaluation of the influences of inland pollution sources and fecal coliform analyses on sea water and shellfish samples in Geoje Bay, pollutants from inland sources did not reach the boundary line of the shellfish growing area after rainfall events of 15 or 22 mm. The bacteriological water quality of the shellfish growing area in Geoje Bay met the Korean standard and US NSSP requirements for approved shellfish growing areas.
Objective: Multi-regional clinical trials have been widely used for accelerating global drug development by multinational pharmaceutical companies. In this study, we aimed to review and analyze the international trends in regulations and guidelines on multi-regional clinical trials by regulatory authorities and international organizations, such as International Conference on Harmonisation, for referring to policies, including development of domestic guidelines for multi-regional clinical trials. Methods: The policies, regulations, and guidelines published by the US Food and Drug Administration, European Medicines Agency, Pharmaceuticals and Medical Devices Agency (Japan), and China Food and Drug Administration were searched, and the International Conference on Harmonisation E17 draft guideline was reviewed. Results: The regulatory authorities in developed countries have developed and implemented regulations and guidelines on multi-regional clinical trials to promote simultaneous global drug development and evaluate the regional differences in drug safety and efficacy. International Conference on Harmonisation developed the draft guideline for planning/designing of multi-regional clinical trials in 2016, which recommends the general principles for strategy-related issues and design of multi-regional clinical trials, and for protocol-related issues, such as consideration of regional variability, subject selection, dose selection, endpoints, comparators, overall sample size, allocation to regions, collecting information on efficacy and safety, and statistical analysis. Conclusion: It is important to understand the international regulatory requirements for designing and planning of multi-regional clinical trials for global drug development. Moreover, it is necessary to prepare multi-regional clinical trial guidelines in accordance with the Korean regulation for clinical trials and drug administration.
Kim, Soo-Youn;Yang, Il-Sun;Yi, Bo-Sook;Baek, Seung-Hee;Shin, Seo-Young;Lee, Hae-Young;Park, Moon-Kyung;Kim, Young-Shin
Korean Journal of Community Nutrition
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v.16
no.6
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pp.730-739
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2011
The purpose of this study was to analyze the differences between child-care facilities and kindergartens towards the need for foodservice support by Center for Child-Care Foodservice Management (CCFSM). For this study, questionnaires were sent out from August of 2008 to April of 2009 to directors of 1,478 child care facilities and 299 kindergartens in Seoul and Gyeonggi-do via postal service. A total of 267 questionnaires were usable with 203 (13.7%) of child-care facilities and 64 (21.4%) of kindergartens. Statistical data were analyzed by SPSS 15.0 for descriptive analysis and t-test. For political and administrative support, government funding for foodservice was the highest need and hiring nutritionists was significantly different by type of facility (p < 0.01). Both child-care facilities (4.29) and kindergartens (4.41) demanded the balanced menu from CCFSM. There were significant differences of "information about food material sanitation management" (p < 0.05), "hygiene safety management method according to working process" (p < 0.05), "hygiene safety management method of foodservice facilities and equipment" (p < 0.05). In education and training contents from center, "types and methods to manage foodservice facilities and equipment" for directors, "dietary education by age" for teachers, and "the rules of personal sanitation and working process" and "gas, electricity and fire prevention" for culinary workers had the highest mean score of requirements.
Lee, Dong Hoon;Oh, Hye Soo;Jang, Jae Min;Jeong, Jong Woon;Yang, Sang Oon
Journal of the Korean Society of Safety
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v.35
no.5
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pp.74-85
/
2020
Smart phone zombie or Smombie means pedestrians who walk without attention to their surroundings because they are focused upon their smart phone. Because the traffic accidents and injuries caused by Smombie have been increased rapidly in recent years, the social attention and policies are needed to prevent it. This study was conducted to analyze Smombie's current status and some solutions used before and to propose new improved method through the latest ICT trend. In this study, we did the field survey to check Smombies at several places in Seoul through people counting, and found that a lot of pedestrians still use the smart phone while walking. And we analyzed many case studies about some solutions to prevent Smombies previously. The case studies include legal regulations, government policies, smart phone app services and facilities that are used before. We studied them through internet searches and reference studies and we also checked the current operating situation as visiting several places that the solutions actually has been operated. Therefore, we found there are some limitations in previous solutions in terms of effectiveness and management. To consider new solution that can be expected to overcome the limitations, we analyzed the latest ICT trends focused on features to utilize the Smombie prevention, especially video recognition and digital signage. In these days, video recognition has been developed rapidly with assistance of AI technology and it can recognize the specific pedestrian's characteristics such as holding smart phone as well as hair style, clothes, backpack and etc. On the other hands, the digital signage is the convergence device that includes big display, network connection and various IoT sensors. It can be used as public media in many places for public services as well as advertising. Through these analysis results, we show the requirements and the user scenario for the improved method to prevent Smombie. Finally, we propose to develop R&D technology to recognize Smombie exactly as pedestrian attributes and to spread creative contents to increase pedestrian's interest and engagement for Smombie prevention through digital signage.
This research examines the use of Cross Bearing in the Republic of Korea Navy. Specifically, this study focuses on the degrees of errors caused by the order of measuring targets and suggests a new method to determine Advice Course. It then reviews the appropriateness of the contents of Location Report that is regularly to the duty officer during a voyage in a narrow channel. Whenever a naval vessel passes through a narrow channel, many number of sailors are assigned to diverse positions in order to enhance navigational safety. Even though it is possible to easily recognize the location of a ship with helps of various kinds of navigational equipments using state-of-the-art technology, there are still several situations where sailors' efforts are indispensible for calculating the position of their ship : when the ship is damaged during an engagement with enemies and when the enemies interfere (GPS) signals. In addition, the particularity of naval vessels in which many number of crew members can be assigned to various positions supports for the suitability of the use of Cross Bearing in the Navy. This study will contribute to navigational safety of the ROK Navy and fostering junior naval officers' seamanship.
Journal of the Korea Academia-Industrial cooperation Society
/
v.17
no.5
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pp.516-521
/
2016
In this study, we investigated the operation of railroad fire fighting vehicles against fires on trains in a long railway tunnel. In recent years, long railway tunnels (more than 10 km in length) have been built and the number of such tunnels, such as the Geumjeong tunnel (20.3 km in length) on the Gyeongbu high speed line, Solan tunnel (16.7 km in length) on the Yeongdong line and Yulhyeon tunnel (50.3 km in length) on the Suseo high speed line which is scheduled to be opened in the second half of 2016, is increasing. Significant damage is to be expected, due to the increased evacuation time and limited accessibility of fire services when the train is stopped by an urgent fire in the tunnel. Special fire fighting vehicles capable of running on rails have been developed and operated in overseas advanced countries. Therefore, a fire-response system using Unimog vehicles, which can run on road and rail, instead of road vehicles, is necessary. The characteristics of the railway tunnel and thermal environmental change caused by a train fire in a tunnel were analyzed in this study. Also, the operational requirements of the railroad fire fighting vehicles were evaluated by taking into account the specifications of the railroad fire fighting vehicles under development.
Radiation generating devices must be properly shielded for their safe application. Although institutes such as US National Bureau of Standards and National Council on Radiation Protection and Measurements (NCRP) have provided guidelines for shielding X-ray tube of various purposes, industry people tend to rely on 'Half Value Layer (HVL) method' which requires relatively simple calculation compared to the case of those guidelines. The method is based on the fact that the intensity, dose, and air kerma of narrow beam incident on shielding wall decreases by about half as the beam penetrates the HVL thickness of the wall. One can adjust shielding wall thickness to satisfy outside wall dose or air kerma requirements with this calculation. However, this may not always be the case because 1) The strict definition of HVL deals with only Intensity, 2) The situation is different when the beam is not 'narrow'; the beam quality inside the wall is distorted and related changes on outside wall dose or air kerma such as buildup effect occurs. Therefore, sometimes more careful research should be done in order to verify the effect of shielding specific radiation generating device. High energy X-ray tubes which is operated at the voltage above 400 kV that are used for 'heavy' nondestructive inspection is an example. People have less experience in running and shielding such device than in the case of widely-used low energy X-ray tubes operated at the voltage below 300 kV. In this study, Air Kerma value per week, outside concrete shielding wall of various thickness surrounding 450 kVp X-ray tube were calculated using MCNP simulation with the aid of Geometry Splitting method which is a famous Variance Reduction technique. The comparison between simulated result, HVL method result, and NCRP Report 147 safety goal $0.02mGy\;wk^{-1}$ on Air Kerma for the place where the public are free to pass showed that concrete wall of thickness 80 cm is needed to achieve the safety goal. Essentially same result was obtained from the application of HVL method except that it suggest the need of additional 5 cm concrete wall thickness. Therefore, employing the result from HVL method calculation as an conservative upper limit of concrete shielding wall thickness was found to be useful; It would be easy, economic, and reasonable way to set shielding wall thickness.
Journal of the Korean Society of Marine Environment & Safety
/
v.23
no.6
/
pp.739-745
/
2017
Many studies have been conducted to reduce environmental pollution by ships and reduce fuel consumption. As part of this effort, research on power conversion systems through DC distribution systems that link renewable energy with conventional power grids has been pursued as well. The diode rectifiers currently used include many lower harmonics in the input current of the load and distort supply voltage to lower the power quality of the whole system. This distortion of voltage waveforms causes the malfunctions of generators, load devices and inverter pole switching elements, resulting in a large number of switching losses. In this paper, a controller is presented to improve DC output waveforms, the input Power Factor and the THD of an AFE type PWM rectifier used for PLL. DC output voltage waveforms have been improved, and the input Power Factor can now be matched to the unit power factor. In addition, the THD of the input power supply has been proven by simulation to comply with the requirements of IEEE Std514-2014.
Seo, Kiyeol;Son, Pyo-Woong;Han, Younghoon;Park, Sang-Hyun;Lee, Jong-Cheol
Journal of the Korean Society of Marine Environment & Safety
/
v.27
no.6
/
pp.815-821
/
2021
This study addresses on the design of performance monitoring system for the time synchronization service of the enhanced long-range navigation (eLoran) system, which has a representative ground-wave radio broadcast system capable of providing positioning, navigation, timing and data (PNT&D) services. The limitations of time-synchronized systems due to the signal vulnerabilities of the global navigation satellite system (GNSS) are explained, and the performance monitoring system for the eLoran timing service as a backup to the GNSS is proposed. The time synchronization service using eLoran system as well as system configurations and the user requirements in the differential Loran (dLoran) system are described to monitor the time synchronization performance. The results of the designed system are presented for long-term operation in the eLoran testbed environment. As the results of time performance monitoring, we were able to verify the time synchronization precision within 43.71 ns without corrections, 22.52 ns with corrections. Based on these results, the eLoran system can be utilized as a precise time synchronization source for GPS timing backup.
Journal of the Korea Academia-Industrial cooperation Society
/
v.22
no.4
/
pp.403-412
/
2021
Despite strengthening requirements for fire retardancy and applied buildings of insulation panels, the number of fires and influence of damage have increased. In this study, the thermal effects were evaluated as the separation distances, and three types of EPS panel, glass wool panel, and gypsum board panel were then selected. Temperature sensors on the panels were installed vertically from the ground. The fire source on the lamination layer of lumber was ignited by changes in the separation distances (0 cm, 25 cm, 50 cm) from the panels. The test results suggested that the maximum temperature was 349 ℃ in the EPS panel. The inside/outside shape changes were limited by the height of the low and middle positions until the critical point of a 25 cm separation distance. Furthermore, the combustion marks appeared after 500 s on average, and then the EPS panel with a high fire strength showed a broad "U type" pattern, glass wool panel, and gypsum board panel showed medium or narrow "V type" pattern. Therefore, the acquired data can provide valuable information for evaluating the fire risks and verifying fire investigation from buildings composed of these insulation panels.
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