• Toxicological Research
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• 제30권4호
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• pp.251-260
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• 2014

The number of farmers who have suffered from non-fatal acute pesticide poisoning has been reported to vary from 5.7% to 86.7% in South Korea since 1975. Absorption through the skin is the main route of exposure to pesticides for farmers who operate with them. Several in vitro tests using the skins of humans or animal and in vivo tests using laboratory animals are introduced for the assessment of human dermal absorption level of pesticides. The objective of this study is to evaluate and compare international guidelines and strategies of dermal absorption assessments and to propose unique approaches for applications into pesticide registration process in our situation. Until present in our situation, pesticide exposure level to operator is determined just using default value of 10 as for skin absorption ratio because of data shortage. Dermal absorption tests are requested to get exposure level of pesticides and to ultimately know the safety of pesticides for operators through the comparison with the value of AOEL. When the exposure level is higher than AOEL, the pesticide cannot be approved. We reviewed the skin absorption test guidelines recommended by OECD, EFSA and EPA. The EPA recommends assessment of skin absorption of pesticides for humans through the TPA which includes all the results of in vitro human and animal and animal in vivo skin absorption studies. OECD and EFSA, employ a tiered approach, which the requirement of further study depends on the results of the former stage study. OECD guidelines accept the analysis of pesticide level absorbed through skin without radioisotope when the recovery using the non-labeled method is within 80~120%. Various factors are reviewed in this study, including the origin of skin (gender, animal species and sites of skin), thickness, temperature and, etc., which can influence the integrity of results.

• 방사성폐기물학회지
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• 제2권4호
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• pp.279-292
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• 2004

고준위폐기물 기준처분시스템의 건전성과 처분안전성의 실험적 검증에 필수적인 지하처분연구시설의 기본설계 도출을 위한 연구가 수행되었다. 먼저 지하처분연구시설의 부지에 대해 간단히 기술하고, 이 부지에 건설될 지하처분연구시설의 기본개념을 제시하고자 하였다. 제시된 기본개념을 충족시키기 위한 지하처분연구시설의 설계 요구사항을 설정하고, 이러한 기본개념과 설계요구사항을 바탕으로 지하처분연구시설의 기본설계를 수행하였다. 또 향후 지하처분연구시설에서 수행될 연구항목을 도출하였다.

• Journal of Mechanical Science and Technology
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• 제17권10호
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• pp.1450-1457
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• 2003

Structural integrity of either a passenger car or a light truck is one of the basic requirements for a full vehicle engineering and development program. The results of the vehicle product performance are measured in terms of durability, noise/vibration/harshness (NVH), crashworthiness and passenger safety. The level of performance of a vehicle directly affects the marketability, profitability and, most importantly, the future of the automobile manufacturer. In this study, we used the Virtual Proving Ground (VPG) approach for obtaining the dynamic stress or strain history and distribution. The VPG uses a nonlinear, dynamic, finite element code (LS-DYNA) which expands the application boundary outside classic linear, static assumptions. The VPG approach also uses realistic boundary conditions of tire/road surface interactions. To verify the predicted dynamic stress and fatigue critical region, a single bump run test, road load simulation, and field test have been performed. The prediction results were compared with experimental results, and the feasibility of the integrated life prediction methodology was verified.

• 대한기계학회논문집A
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• 제27권3호
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• pp.416-423
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• 2003

During the last ten years, the need has been increased for reducing maintenance cost for aged equipments and ensuring safety, efficiency and profitability of petrochemical and refinery plants. RBI (Risk Based Inspection) methodology is one of the most promising technologies satisfying the need in the field of integrity management. In this study, a user-friendly software, realRBl for RBI based on the API 581 code was developed. This software has modules for evaluating qualitative and semi-quantitative risk level, analyzing quantitative risks using the potential consequences of a failure of the pressure boundary, and assessing the likelihood of failure. A quantitative analysis was performed for 16 columns in a domestic NCC (Naphtha Cracking Center) plant whose operating time reaches about 12 years. Each column was considered as two equipment parts by dividing into top and bottom. Generic column failure frequencies were adjusted based on likelihood data. After determining release rate, release duration and release mass for each failure scenario, flammable/explosive and toxic consequences were assessed. Current risks for 32 equipment parts were evaluated and risk based prioritization were determined as a final result.

• 융합보안논문지
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• 제10권4호
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• pp.13-19
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• 2010

시대의 흐름에 따라 기업의 지속적인 비지니스 연계 보증을 위하여 IT의 비중이 높아지면서, IT가 조직의 하나의 부분으로서 작용하는 것이 아닌 전사적인 차원에서 정보화 사회의 경쟁 화두로서 인식되어가고 있다. 정보보안 거버넌스는 정보의 무결성, 서비스 연속성, 정보자산의 보호라는 3가지 목적으로 시작된다. 이는 기업 거버넌스에 필수적이며 투명한 부분이 되어야 하고, IT프레임워크와 연계되어야 한다. 기존의 정보보안 거버넌스 프레임워크는 그 범위가 넓어 소규모 기업 거버넌스와 이해관계를 가지지 못한 문제점이 있다. 따라서 본 논문은 단순화된 정보보안 거버넌스 프레임워크를 제안하여, 문제점을 해결하고, 제안하는 프레임워크의 안전성 분석과 효율성 분석을 통하여 제안 방법의 효율성에 관하여 알아보았다.

• Nuclear Engineering and Technology
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• 제46권1호
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• pp.73-80
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• 2014

A concrete cask is an option for spent nuclear fuel interim storage. A concrete cask usually consists of a metallic canister which confines the spent nuclear fuel assemblies and a concrete overpack. When the overpack undergoes a missile impact, which might be caused by a tornado or an aircraft crash, it should sustain an acceptable level of structural integrity so that its radiation shielding capability and the retrievability of the canister are maintained. A missile impact against a concrete overpack produces two damage modes, local damage and global damage. In conventional approaches [1], those two damage modes are decoupled and evaluated separately. The local damage of concrete is usually evaluated by empirical formulas, while the global damage is evaluated by finite element analysis. However, this decoupled approach may lead to a very conservative estimation of both damages. In this research, finite element analysis with material failure models and element erosion is applied to the evaluation of local and global damage of concrete overpacks under high speed missile impacts. Two types of concrete overpacks with different configurations are considered. The numerical simulation results are compared with test results, and it is shown that the finite element analysis predicts both local and global damage qualitatively well, but the quantitative accuracy of the results are highly dependent on the fine-tuning of material and failure parameters.

• Advances in Computational Design
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• 제4권2호
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• pp.91-118
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• 2019

Every year, many people are severely injured or lose their lives in accidents such as fire, chemical spill, public pandemonium, school shooting, and workplace violence. Research indicates that the fate of people in an emergency situation involving one or more hazards depends not only on the design of the space (e.g., residential building, industrial facility, shopping mall, sports stadium, school, concert hall) in which the incident occurs, but also on a host of other factors including but not limited to (a) occupants' characteristics, (b) level of familiarity with and cognition of the surroundings, and (c) effectiveness of hazard intervention systems. In this paper, we present EVAQ, a simulation framework for modeling large crowd evacuation by taking into account occupants' behaviors and interactions during an emergency. In particular, human's personal (i.e., age, gender, disability) and interpersonal (i.e., group behavior and interactions) attributes are parameterized in a hazard-impacted environment. In addition, different hazard types (e.g., fire, lone wolf attacker) and propagation patterns, as well as intervention schemes (simulating building repellent systems, firefighters, law enforcement) are modeled. Next, the application of EVAQ to crowd egress planning in an airport terminal under human attack, and a shopping mall in fire emergency are presented and results are discussed. Finally, a validation test is performed using real world data from a past building fire incident to assess the reliability and integrity of EVAQ in comparison with existing evacuation modeling tools.

• Nuclear Engineering and Technology
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• 제54권1호
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• pp.30-35
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• 2022

In a nuclear reactor, gamma radiation is the dominant energy deposition in non-fuel regions. Heat is generated upon gamma deposition and consequently affects the mechanical and thermal structure of the material. Therefore, the safety of samples should be carefully considered so that their integrity and quality can be retained. To evaluate relevant parameters, an in-core gamma thermometer (GT) was used to measure gamma heating (GH) throughout the operation of the McMaster nuclear reactor (MNR) at four irradiation sites. Additionally, a Monte Carlo reactor physics code (Serpent-2) was utilized to model the MNR with the GT located in the same irradiation sites used in the measurement to verify its predictions against measured GH. This research aids in the development of modeling, calculation, and prediction of the GH utilizing Serpent-2 as well as implementing a new GH measurement at the MNR core. After all uncertainties were quantified for both approaches, comparable GH profiles were observed between the measurements and calculations. In addition, the GH values found in the four sites represent a strong level of radiation based on the distance of the sample from the core. In this study, the maximum and minimum GH values were found at 0.32 ± 0.05 W/g and 0.15 ± 0.02 W/g, respectively, corresponding to 320 Sv/s and 150 Sv/s. These values are crucial to be considered whenever sample is planned to be irradiated inside the MNR core.

• Smart Structures and Systems
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• 제33권3호
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• pp.227-241
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• 2024

Safety and structural integrity of civil structures, like bridges and buildings, can be substantially enhanced by employing appropriate structural health monitoring (SHM) techniques for timely diagnosis of incipient damages. The information gathered from health monitoring of important infrastructure helps in making informed decisions on their maintenance. This ensures smooth, uninterrupted operation of the civil infrastructure and also cuts down the overall maintenance cost. With an early warning system, SHM can protect human life during major structural failures. A real-time online damage localization technique is proposed using only the vibration measurements in this paper. The concept of the 'Degree of Scatter' (DoS) of the vibration measurements is used to generate a spatial profile, and fractal dimension theory is used for damage detection and localization in the proposed two-phase algorithm. Further, it ensures robustness against environmental and operational variability (EoV). The proposed method works only with output-only responses and does not require correlated finite element models. Investigations are carried out to test the presented algorithm, using the synthetic data generated from a simply supported beam, a 25-storey shear building model, and also experimental data obtained from the lab-level experiments on a steel I-beam and a ten-storey framed structure. The investigations suggest that the proposed damage localization algorithm is capable of isolating the influence of the confounding factors associated with EoV while detecting and localizing damage even with noisy measurements.

• Ocean Systems Engineering
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• 제13권4호
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• pp.385-399
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• 2023

A collision between a ship and an offshore platform may result in structural damage and closure; therefore, damage analysis is required to ensure the platform's integrity. This paper presents a damage assessment of a three-legged jacket platform subjected to ship collisions using the industrial finite element program Bentley SACS. This study considers two ships with displacements of 2,000 and 5,000 tons and forward speeds of 2 and 6.17 meters per second. Ship collision loads are applied as a simplified point load on the center of the platform's legs at inclinations of 1/7 and 1/8; diagonal bracing is also included. The jacket platform is modelled as beam elements, with the exception of the impacted jacket members, which are modelled as nonlinear shell elements with elasto-plastic material and constant isotropic hardening to provide realistic dented behavior due to ship collision load. The structural response is investigated, including kinetic energy transfer, stress distribution, and denting damage. The simulation results revealed that the difference in leg inclination has no effect on the level of localized denting damage. However, it was discovered that a leg with a greater inclination (1/8) resists structural displacement more effectively and absorbs less kinetic energy. In this instance, the three-legged platform collapses due to the absorption of 27.30 MJ of energy. These results provide crucial insights for enhancing offshore platform resilience and safety in high-traffic maritime regions, with implications for design and collision mitigation strategies.