• Title/Summary/Keyword: Safety grade

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Safety and efficacy of pemetrexed for the treatment of lung adenocarcinoma in patients with various stages of chronic kidney disease

  • Yang, Jieun;park, Ji Eun;Jo, Jaemin;Kim, Young Ree;Chang, Jee Won;Han, Sang Hoon;Han, Chi Wha
    • Journal of Medicine and Life Science
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    • v.19 no.1
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    • pp.14-19
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    • 2022
  • We investigated the safety and efficacy of pemetrexed monotherapy in patients with lung adenocarcinoma and various renal conditions, including chronic kidney disease. We also analyzed whether baseline renal function affected progression-free survival (PFS). We retrospectively analyzed 71 patients who received maintenance-and second-line pemetrexed monotherapy. Patients were divided into two groups according to estimated glomerular filtration rate (eGFR): fair eGFR (>60 mL/min/1.73 m2) and lower eGFR (59 mL/min/1.73 m2 or less). The safety and efficacy were evaluated for each group. Median ages were 73.2 years in the lower eGFR group (n=28) and 64.5 years in the fair eGFR group (n=43). Patients with a lower eGFR achieved a median PFS of 4.7 months, while the median PFS for patients with a fair eGFR was 2.7 months. The difference between the two groups was not statistically significant (P=0.075). Both groups showed treatment-related low-grade hematological and non-hematological adverse events. Pemetrexed monotherapy is safe and effective in patients with lung adenocarcinoma with a lower eGFR.

Knowledge and attitude change towards radiation protection after radiation safety management education in dental hygiene students (치위생과 학생들의 학업관련 특성에 따른 방사선안전관리 교육 후 방사선 방어에 대한 지식과 태도의 변화)

  • Kim, Sung-Ae;Lee, Ji-Young;Hwang, Se-Hyun;Cho, Mi-Suk;Park, Jung-Hyun;Jung, Nam-Yeong;Yu, Byeng-Chul
    • Journal of Korean society of Dental Hygiene
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    • v.15 no.1
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    • pp.101-109
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    • 2015
  • Objectives: The purpose of the study is to investigate the knowledge and attitude towards radiation protection after radiation safety management education in dental hygiene students. Methods: After receiving informed consents, a self-reported questionnaire was carried out for 135 dental hygiene students in Busan on June 17 for preliminary survey and September 3 for post-education survey, 2011. The questionnaire was modified from Han and consisted of 5 questions of general characteristics, 6 questions of radiation use, 7 questions of scholastic characteristics, 15 questions of knowledge towards radiation safety management, and 15 questions of attitude towards radiation safety management. Cronbach's alpha was 0.808 in the knowledge towards radiation safety management. Attitude towards radiation safety management included 15 questions of general attitude towards radiation safety management, individual and patient, and attitude toward radiation exposure reduction measured by Likert 5 scale. Cronbach's alpha was 0.970 in the attitude towards radiation safety management. Data were analyzed using SAS version 9.2 for educational analysis, technical analysis and multivariate analysis, paired t-test, and GLM. Results: Significant differences were shown in the knowledge and attitudes towards radiation safety management; the level of knowledge was respectively $9.8{\pm}3.0$ and $12.9{\pm}1.9$ points before and after education, and the level of attitude was $4.28{\pm}0.51$ and $4.53{\pm}0.47$ before and after the education. The levels of knowledge and attitude according to general characteristics showed a significant differences in grade and academic results. Post-education survey suggested that the education is very important and necessary and can change the knowledge and attitude towards radiation safety management in the dental hygiene students. Conclusions: Through the radiation safety management education, the levels of knowledge and attitude towards radiation safety management have changed significantly, which showed that the radiation safety management education proved to be very effective. Therefore, an effective radiation safety management education program is necessary to improve the levels of knowledge and attitude towards radiation safety management in the dental hygiene students.

Korean adolescents' indigenous understanding of safety: With specific focus on cognitive representation of accidents, safety efficacy and parental influence (한국 청소년의 안전에 대한 토착심리 분석: 안전사고에 대한 표상과 안전효능감 및 부모의 영향을 중심으로)

  • Young-Shin Park
    • Korean Journal of Culture and Social Issue
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    • v.9 no.spc
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    • pp.89-105
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    • 2003
  • The purpose of this paper is to explore Korean adolescents' understanding of safety using the indigenous psychologies approach. This paper examines Korean adolescents' experience of the type of accidents they were involved in, what they perceived to be the cause of the accident, the type of social support received after the accident, and the prevention needed to avoid future accidents. The indigenous understanding of accidents is examined according to the grade level of the students, gender, and safety efficacy beliefs. Second, to examine the changes in the safety efficacy beliefs, the differences across primary, junior high, and senior high school students are examined. Third, the relationship between safety efficacy belief and attitudes toward preventing future accidents is explored. Third, the parental influence on adolescents' safety efficacy belief is examined by analyzing the influence of their socio-economic status and their safety efficacy belief on their children's safety efficacy belief and behavior. The review of the results can be summarized into the following five main points: (1) decrease in safety efficacy belief with increasing age, (2) positive relationship between safety efficacy belief and behavior, (3) the utility of the indigenous psychologies approach, (4) the parental influence on their children's safety efficacy beliefs and behavior, and (5) the need to further explore, promote, and educate the importance of human life and quality of life by preventing accidents and promoting safety consciousness and behavior in Korea.

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Safety-practice and Its Related Factors among Elementary students in a rural area (일부 초등학생의 안전실천 관련요인)

  • Lee, Young-Mee
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.10 no.5
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    • pp.1115-1125
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    • 2009
  • Purpose: The purpose of this study was to investigate the Safety-practice and Its Related Factors among Elementary students in rural area, to provide the basic data for prevention for safety accident occurrence in order to improve the QOL. Methods: The subjects of this study were 549 elementary students using self-report questionnaires. The collected data was analyzed using descriptive statistics, t-test, ANOVA, Scheffe's test, Pearson correlation coefficient and stepwise multiple regression with SPSS 12.0 Program. Results: The mean score for level of the safety awareness was 3.55(${\pm}.36$) and of the safety practice, 2.98(${\pm}.48$). The score of Safety-practice was statistically significant difference according to students' gender(p= .028) and students' grade(p= .004), the number of friends(p= .002), the level of school life adaptation(p= .000), recognized learning proficiency(p= .000), personality(p= .005), curiosity(p= .003), the level of demand for safety education(p= .000), the level of safety-education conducted by parents(p= .000), the level of safety-education conducted by teacher(p= .000). Stepwise multiple regression analysis for Safety-practice revealed that the most powerful predictor was level of Safety-awareness and self-esteem, the level of safety-education conducted by parents explained 28.8% of the variance. Conclusions: Therefore, it is necessary to develop safety practice promotion program in order to enhance the quality of life of elementary students. Future studies need to be pursued to find various variances.

A Diagnostic Study of safety education in elementary schools based on PRECEDE Model (PRECEDE 모형을 이용한 일부 초등학교 안전교육의 진단적 연구)

  • 백경원;이명선
    • Korean Journal of Health Education and Promotion
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    • v.18 no.1
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    • pp.35-47
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    • 2001
  • As the complexity of the our environment is further complicated by advancements in industry and increase in vehicle traffic flow, the incidents of injury causing accidents are on the rise. Consequently, there is increasing emphasis on the importance of systematic and continual safety education for injury preventive behaviors. This study investigates safety related problems of elementary school students based on the PRECEDE model, proposed by Green et al.(1980 Green), to comprehensively identify the requirements of school safety education. The identified requirements were used to diagnose the current state of elementary school safety education through the analysis of multidimensional factors. A questionnaire survey was conducted on 594 sixth grade students from randomly selected 4 schools in Seoul to examine their injury preventive behaviors and to determine the educational diagnosis variables that affect it. The duration of the survey was 3 weeks starting from April 12, 1999 to May 8, 1999. A summary of the survey results are presented below; 1. Situations in which accidents have occurred were, in their order of frequency, ‘during play or sports activities within the school grounds’ was most frequent at 59.6%, ‘during play on local streets’ at 49.5%, and ‘traffic accidents’ at 41.6%. 2. Categorization of the injury preventive behavior showed that ‘not playing at high traffic flow locations such as streets and construction sites’ had the higher level of observance, while ‘wearing of helmets and joint protection devices during playing’ was least observed. 3. Considering injury preventive behaviors in relation to educational diagnosis variables indicated, for predisposing factors, lower ‘perception to injury accidents’ (p〈0.001) combined with higher ‘concerns for injury accidents’(p〈0.001), ‘practice of preventive behavior’(p〈0.001), and ‘the level of safety knowledge’(p〈0.001) resulted in significantly higher observance of injury preventive behaviors. For enabling factors, higher ‘perceived level of the school safety education’ (p〈0.001) and ‘availability of safety education resources’(p〈0.01) indicated significantly higher observance of injury preventive behaviors. For the reinforcing factor, frequent exposure to ‘safety education brochure’ (p〈0.01) and ‘audio-visual material for safety education’(p〈0.01) combined with more ‘regional safety education’ (p〈0.01), ‘home safety education’ (p〈0.01), ‘school safety education’(p〈0.001), and, ‘parents’ observance of preventive behaviors' (p〈0.001) showed significantly higher observance of injury preventive behaviors. 4. An analysis of the factors that affect injury preventive behaviors showed that the enabling factor ‘awareness of school safety education’ had the highest correlation with injury preventive behaviors followed by factors, in their order of significance, ‘practice of preventive behavior’, ‘perception to injury accidents’, ‘level of safety knowledge’, ‘parents’ observances of preventive behaviors', and ‘concerns for injury accidents.’

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The introduction of Traffic Inducement Security System in Korea - Centering on Curriculums - (한국의 교통유도경비 도입방안 -교과과정을 중심으로-)

  • Lee, Sang-Won;Lee,, Seung-Chal
    • Korean Security Journal
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    • no.25
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    • pp.147-164
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    • 2010
  • A variety of work zone including road single-sharing construction add surrounding disorder and increase inconvenience of vehicles and pedestrians and furthermore danger of traffic accidents, which sometimes result in human life damages. Traffic delay due to vehicles and users generating in the course of using large-scale multiplex facilities bring about a great economic loss. Now, a lot of regulations and laws related to traffic safety system on construction sites etc. are established, but can not display efficacy desirably. It brings about continuous economic loss due to human life accidents and delay. For the purpose of solving the problems, it is necessary to import systems such as traffic inducement Security (Japan) and traffic controller (CANADA, USA) This article suggest how improve civil safety and reduce Social cost. therefore This thesis aims at analyzing advanced cases of foreign countries, looking into Korean status, and presenting importing ways of traffic inducement Security appropriate to Korea. It is reasonable to grant grade1, grade2, and technical experts to traffic inducement Security who pass regulated educations and examinations. In addition, by reversing regulations and laws, it is necessary only those who have the licenses of traffic induction guarder etc. can establish construction sites and disordered places on roads. Theory educations for education time must include basic educations and expert educations. Basic educations must include understanding regulations and laws and understanding affairs. Expert educations must include traffic control, safety educations, understanding of traffic accidents, operation of traffic control facilities, and traffic accident settlements. Traffic affairs educations must include traffic induction affairs in sites (hand signals, safety material establishment, traffic accident settlements, and urgent treatments).

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The Effect of Consumer Knowledge, Money Attitude and Consumption Values on Rational Consumption Behavior in Adolescent (청소년의 소비자지식, 돈에 대한 태도 및 소비가치가 합리적 소비행동에 미치는 영향)

  • Seo, Eun-Suk;Jang, Yoon-Ok
    • Journal of Families and Better Life
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    • v.26 no.5
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    • pp.241-257
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    • 2008
  • The purpose of this study waw to investigate the effect of consumer knowledge of adolescents, money attitudes and consumption values on rational consumption behavior and the direct and indirect effects of these variables on rational consumption behavior. The subjects of this study were 524 students who were in the first grade and second grade of high school in Daegu. Multiple Regression Analysis and Path Analysis were employed for the data analysis. The major findings of this study were as follows: First, the knowledge of money management, the purchase knowledge and the consumerism knowledge effected on the money attitude, which regarded money as an instrument of future safety. Among these, it was found that the money management knowledge had the highest affect on this money attitude. The result suggests that the consumer knowledge affects desirable money attitude which regarded money as an instrument of future safety, and then consumer education influences positively money attitude. Second, the money attitude which regarded money as an instrument of future safety affected consumption values most, and the money attitude which regarded money as a means for approval of another person affected the ostentation, the conformity, the discrimination and the aesthetic enjoyment of consumption values. Third, the present study showed that the money attitude which regards money as an instrument of future safety and the economical consumption values were the important factor which affecting each subdimension of the rational consumption behavior. The result suggests the adolescents, who managed money well, saved it for the future, and saved the resources as much as possible when consuming, behaved rational and planned way through all process all process all consumption behaviors. Fourth, the consumer knowledge did not affect the rational consumption behavior directly, but indirectly through the money attitude and the consumption values. Therefore, the consumer knowledge, the money attitude and the consumption values were the important factor for the rational consumption behavior, and it revealed money attitude and consumption values played role as mediate variable. This study results suggest the consumer knowledge that adolescent have learned in school was theoretical and abstract, so it does not affect directly the rational consumption behavior. However these consumer consumption values affect the consumption behavior.

Study of Effectiveness of Signal Preemption Strategy Depending on Train Speed at Intersections Near Highway-Railroad Grade Crossings (철도건널목 인근 신호교차로에서의 우선신호 전략 비교분석(열차속도를 중심으로))

  • Jo, Han-Seon;Kim, Won-Ho;O, Ju-Taek;Sim, Jae-Ik
    • Journal of Korean Society of Transportation
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    • v.25 no.2 s.95
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    • pp.17-26
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    • 2007
  • Because the prime objective of the current preemption methods at signalized intersections near highway-railroad grade crossings(IHRGCs) is to clear the crossing, secondary objectives such as safe pedestrian crossing time and minimized delay often are given less consideration or are ignored completely during the preemption. Under certain circumstances state-of-the-practice traffic signal preemption strategies may cause serious pedestrian safety and efficiency problems at IHRGCs. An improved transition preemption strategy(ITPS) that is specifically designed to improve intersection performance while maintaining or improving the current level of safety was developed by Cho and Rilett. Even if the new transition preemption strategy improved both the safety and efficiency of IHRGCs, the performance of the strategy is affected by train speed. Understanding the impact of this factor is essential in order to implement ITPS. In this paper, the effects of train speed were analyzed using a VISSIM simulation model which was calibrated to field conditions. It was concluded that the delay is affected more by train speed than the transitional preemption strategy and the safety of the intersection is not affected by train speed once an advanced preemption warning time(APWT) is equal to or greater than 90 seconds.

Estimation of citizen's willingness to pay for water quality improvement on urban rivers (도시하천 수질개선을 위한 시민의 지불의사액 추정 연구)

  • Kang, Jiyoon;Yang, Jinwoo;Hwang, Youngsoon;Kim, Keewook
    • Journal of Korea Water Resources Association
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    • v.56 no.3
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    • pp.225-233
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    • 2023
  • Urban rivers and their surrounding environments have been altered due to factors such as rapid economic growth and urban development. This alteration have caused the rivers to lose their original value and become exposed to various pollution, resulting decrease in citizens' quality of life. This study aims to estimate citizens' Willingness To Pay (WTP) for water quality improvement in Suyeong River in Busan. To estimate the non-market value of the Suyeong River, the WTP of Busan citizens for water quality improvement was estimated, applying Contingent Valuation Method (CVM). The WTP for improving the water quality from Grade 4(polluted water) to Grade 2(game fish like bass can live in it) was estimated using the water quality ladder concept of the US Environmental Protection Agency, assuming annual donations for five years. For the CVM, the logistic distribution and Spike Model were adopted. As a result, citizens residing in the surrounding area of Suyeong River expressed a higher WTP. Considering more than half of the Busan citizens are aware of the "conservation of nature and ecosystems" as a major function of the Suyeong River, this higher WTP could serve as a basis for improving the value of urban rivers.

Production and evaluation of children's dietary life safety index data on metropolitan cities and provinces in Korea

  • Choi, Young-Sun;Lee, Jung-Sug;Kim, Hye-Young;Kwak, Tong-Kyung;Chung, Hae Rang;Kwon, Sehyug;Choi, Youn-Ju;Lee, Soon-Kyu;Kang, Myung-Hee
    • Nutrition Research and Practice
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    • v.6 no.6
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    • pp.542-550
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    • 2012
  • This pilot study was performed to produce data of the Children's Dietary Life Safety (CDLS) Index which is required by the Special Act on Safety Management of Children's Dietary Life and to evaluate the CDLS Index for 7 metropolitan cities and 9 provinces in Korea. To calculate the CDLS Index score, data regarding the evaluation indicators in the children's food safety domain and children's nutrition safety domain were collected from the local governments in 2009. For data regarding the indicators in the children's perception & practice domain, a survey was conducted on 2,400 5th grade children selected by stratified sampling in 16 local areas. Relative scores of indicators in each domain were calculated using the data provided by local governments and the survey, the weights are applied on relative scores, and then the CDLS Index scores of local governments were produced by adding scores of the 3 domains. The national average scores of the food safety domain, the nutrition safety domain and the perception and practice domain were 23.74 (14.67-26.50 on a 40-point scale), 16.65 (12.25-19.60 on a 40-point scale), and 14.88 (14.16-15.30 on a 20-point scale), respectively. The national average score of the CDLS Index which was produced by adding the scores of the three domains was 55.27 ranging 46.44-58.94 among local governments. The CDLS Index scores produced in this study may provide the motivation for comparing relative accomplishment and for actively achieving the goals through establishment of the target value by local governments. Also, it can be used as useful data for the establishment and improvement of children's dietary life safety policy at the national level.