• Title/Summary/Keyword: Safety evaluation test

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Braking Force Test Evaluation Dynamometer Development of Vehicle (차량용 브레이크 제동력 평가 다이나모미터 개발)

  • Kwon, Byeong-Heon;Yoon, Pil-Hwon;Lee, Seon-Bong
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.5
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    • pp.56-65
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    • 2019
  • Recently, automobiles have been developed for safety and environmental reasons. Particularly, awareness of automobile safety is changing significantly. As a result, safety systems developed by ADAS have emerged. However, the period of mass production through ADAS development and test evaluation is long. Therefore, in this paper, we develop a brake dynamometer to shorten the time required for ADAS development and test evaluation. In addition, the developed brake dynamometer satisfies the international standard JIS D-0210, and the user can evaluate the braking force by selecting test conditions and test method for each mode of ADAS. We use the ACC, LKAS, and AEB scenarios proposed in previous studies to verify the reliability of the developed brake dynamometer. The developed brake dynamometer was verified by comparing the test values and the calculated values using theoretical formulas of the proposed ADAS mode based on previous studies. In addition, it is expected that the performance evaluation of brake parts for each ADAS mode will be possible in an environment where the vehicle test of ADAS is not possible in the future.

Guideline for Bioequivalence Studies of Controlled Release Products (서방성 제제의 생물학적동등성시험을 위한 가이드라인)

  • Seo, Hyun-Ok;Kim, So-Hee;Ahn, Mee-Ryung;Ahn, Choong-Yul;Park, Hye-Jin;Oh, Eun-Kyung;Lee, Eun-Ju;Kim, Bo-Yeon;Kim, Min-Jeong;Woo, Na-Ry;Seo, Hee-Won;Chung, Soo-Youn
    • Journal of Pharmaceutical Investigation
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    • v.40 no.1
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    • pp.63-66
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    • 2010
  • The "Guidance Document for Bioequivalence Study" was revised for adding to bioequivalence studies of controlled-release products after meal(Korea Food & Drug Administration Notification #2008-22, 2008.5.7). The bioequivalence study design for controlled-release products is $2{\times}2$ crossover under fast and fed condition in respect. For studies of controlled-release products under fed study, the same high-fat diet should be taken within 20 minutes in at least a 10-hour fasting state. The drug products should be administered 30 minutes after the meal started. A high-fat(more than 35 percent of total caloric content of the meal) and high-calorie(over 900 calories) meal is recommended as a test meal for fed BE studies.

Comparison of 5 Assays for Quantification of Antibody to Hepatitis B Virus Surface Antigen with Immunoglobulin G Preparations (면역글로불린제제 효능평가를 위한 5종 B형간염 표면항원항체검출법의 비교)

  • Shin, In-Soo;Lee, Yoo-Kyoung;Kim, Oh-Jung;Ban, Sang-Ja
    • KSBB Journal
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    • v.26 no.2
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    • pp.157-164
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    • 2011
  • Five assays for anti-HBs were compared to improve potency test of Human lgG preparations. The three commercial EIA kits were optimized including dose response curve ranges and compared by conducting a co-laboratory study. After selecting the most reproducible EIA kit, methods comparison was performed with 22 samples in 5 different days. As a result, EIA (7.7 ${\pm}$ 5.3%) and MEIA (AxSYM: 3.7 ${\pm}$ 1.9%, IMx: 1.6 ${\pm}$ 0.8%) showed precision and accuracy (100.1 ${\pm}$ 12.6%). Therefore, the validated EIA assay was established and it is believed to be comparable to current MEIA.

Evaluation of Degraded Materials by Automated Ball Indentation(ABI) Technique (압입법을 이용한 재료의 열화도 평가)

  • 김석민;석창성;이승석;권재도
    • Journal of the Korean Society of Safety
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    • v.15 no.1
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    • pp.28-35
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    • 2000
  • As huge energy transfer systems like a nuclear power plant, steam power plant and petrochemical plant are operated for a long time, mechanical properties are changed by degradation. The life time of the systems can be affected by the mechanical properties. So determination of the integrity of the metallic structure is required either to en4sure that failure will not occur during the service life of the components or to evaluate the lifetime extension of the structure. An automated ball indentation(ABI) method was developed as a non-destructive technique for evaluating the integrity of such metallic components. In this paper, we would like to present the aging evaluation technique by the ABI method. The five classes of the thermally aged CF8M specimens were prepared using an artificially accelerated aging method. After holding 100, 300, 900, 1800 and 3600 hours at 43$0^{\circ}C$, the specimens were cooled down using water to room temperature respectively. The tensile test, hardness test, charpy impact test, ABI test were performed. The results of the fracture test were compared with those of ABI test and the new evaluation technique of the integrity of metallic structures was developed.

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Evaluating Staircase Safety Using BIM-based Virtual Simulation: Focusing on the Elderly in the Republic of Korea

  • Yang, Hyuncheul;Jeong, Kwangbok;Kim, Sohyun;Lee, Jaewook
    • International conference on construction engineering and project management
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    • 2022.06a
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    • pp.1146-1153
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    • 2022
  • As the population is aging, accidents involving elderly people are also increasing (2014:11,667 persons; 2018: 11,797 persons). In the case of the elderly population, falling accidents are the primary direct or indirect causes of death; in particular, they face an elevated risk of staircase falls. This study proposes a method of evaluating the safety of staircases using Building Information Modeling (BIM)-based virtual simulation. By making a virtual user with the behavioral characteristics of the elderly respond to a staircase in a BIM model, its safety performance can be evaluated. The evaluation criteria were derived from regulations, elements, and characteristics relevant to the safety of staircases. To validate the proposed method, safety evaluation tests were simulated on actual staircases. The evaluation result of the test simulation shows the safety scores of 1.97 points for the elderly user and 2.95 points for the average male adult user against a required safety score of a minimum of 2 points. That is, safety is relative to users as the safety of the same staircase can be different depending upon the different behavioral characteristics of users. The study suggests that the risk of staircase-related fall accidents to the elderly can be reduced by improving staircase designs through the proposed method.

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A safety evaluation on the loading and vibration test for transport freight car of cold rolled coil sheet (냉연코일강판 수송용 화차의 안전성 평가를 위한 차체하중시험과 진동시험)

  • 김원경;정종덕;윤성철;홍용기
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2003.06a
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    • pp.1499-1502
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    • 2003
  • This paper describes the result of carbody and vibration test for freight car. The purpose of the test is to evaluate an safety which carbody structure shall be considered fully sufficient rigidity so as to load a freight car under maximum load and operating condition on line track. The test carbody is constructed by RS korea co., LTD. in accordance with KNR specfication. The test cases of the carbody is tested the vertical load and compressive load to verify the strength and stillness. The vibration test is tested for analysis and evaluation of vibration, to allow for the fact that mechanical vibration in railway vehicles have specific characteristics.

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A safety evaluation on the loading and vibration test of freight car (화차 안전성 평가를 위한 차체 정하중시험 및 진동시험)

  • 권성태;정종덕;김원경;홍용기;허현무
    • Proceedings of the KSR Conference
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    • 2002.10a
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    • pp.92-97
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    • 2002
  • This paper describes the result of carbody and vibration test for freight car. The purpose of the test is to evaluate an safety which carbody structure shall be considered fully sufficient rigidity so as to load a freight car under maximum load and operating condition on line track. The test carbody is constructed by RS korea co., LTD. in accordance with KNR specification. The test cases of the carbody is tested the vertical load and compressive load to verify the strength and stiffness. The vibration test is tested for analysis and evaluation of vibration, to allow for the fact that mechanical vibration in railway vehicles have specific characteristics.

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Selection and Validation of an Analytical Method for Trifludimoxazin in Agricultural Products with LC-MS/MS (LC-MS/MS를 이용한 농산물 중 Trifludimoxazin의 시험법 선정 및 검증)

  • Sun Young Gu;Su Jung Lee;So eun Lee;Chae Young Park;Jung Mi Lee;Inju Park;Yun Mi Chung;Gui Hyun Jang;Guiim Moon
    • Journal of Food Hygiene and Safety
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    • v.38 no.3
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    • pp.79-88
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    • 2023
  • Trifludimoxazin is a triazinone herbicide that inhibits the synthesis of protoporphyrinogen oxidase (PPO). The lack of PPO damages the cell membranes, leading to plant cell death. An official analytical method for the safety management of trifludimoxazin is necessary because it is a newly registered herbicide in Korea. Therefore, this study aimed to develop a residual analysis method to detect trifludimoxazin in five representative agricultural products. The EN method was established as the final extraction method by comparing the recovery test and matrix effect with those of the QuEChERS method. Various sorbent agents were used to establish the clean-up method, and no differences were observed among them. MgSO4 and PSA were selected as the final clean-up conditions. We used LC-MS/MS considering the selectivity and sensitivity of the target pesticide and analyzed the samples in the MRM mode. The recovery test results using the established analysis method and inter-laboratory validation showed a valid range of 73.5-100.7%, with a relative standard deviation and coefficient of variation less than 12.6% and 14.5%, respectively. Therefore, the presence of trifludimoxazin can be analyzed using a modified QuEChERS method, which is widely available in Korea to ensure the safety of residual insecticides.

A study on Evaluation Methods for Safety and Performance of Electrical Stimulations for Home Use (개인용전기자극기 성능 및 안전성 평가 방법 연구)

  • Kim, San;Jang, Moo-Young;Hwang, Yoon Su;Lee, Ki-Hun;Hur, Chan-Hoi;Hong, Choongman
    • Journal of the Institute of Electronics and Information Engineers
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    • v.50 no.3
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    • pp.187-202
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    • 2013
  • The electronic medical device industry and the relevant market have been greatly expanded owing to various factors, such as the advent of the aged society and the spread of the desire for well-being in developed countries, and rapid development of China, India and other emerging markets. The electrical stimulator is one of electronic medical devices most commonly used in homes. The electrical stimulator is widely used for pain relief, rehabilitation, muscle conditioning and others. Since it is mainly used in homes, it is very important to assure the safety and performance for protection of users. However, there is no guideline on evaluation of safety and performance of such electrical stimulator for home use. In this study, various local and foreign references were reviewed to develop the internationally harmonized procedures for safety and performance evaluation of the electrical stimulator and test items, specifications and methods are proposed. In addition, such proposed test items were validated to decide the internationally harmonized tests for safety and performance evaluation. This study will contribute to improvement of quality and safety of electrical stimulators for home use and help the Korean medical device industry have the international competitiveness.

A Comparative Study on Test and Evaluation Items for Various Railway Systems (철도시스템 시운전 시험 평가 항목 비교 연구)

  • 정흥채;엄기영;김석원;서정원;신종한
    • Proceedings of the KSR Conference
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    • 2002.10a
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    • pp.232-237
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    • 2002
  • A field of test and evaluation plays an important role in railway system in the safety and reliability aspects. In this paper, test and evaluation items for various railway systems i.e., conventional railway system, tilting system, and high speed railway system, were compared to analyze characteristics of the systems.

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