• The Korean Journal of Pesticide Science
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• v.16 no.3
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• pp.261-266
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• 2012

It is common to use many experiment animals to evaluate the toxicity of chemicals including pesticides. For protecting animal, the concepts of 3R (Reduction, Replacement, Refinement) were introduced and in vitro alternatives methods actively have been developed all over the world. Many experimental animals for toxicological tests have been used, so that it is important to establish the alternative methods. In this study, the alternative method using reconstituted human skin model (Keraskin$^{TM}$) was conducted for classification of skin irritation on pesticides. Sixteen formulations selected on the basis of the degree of irritation were treated by Keraskin$^{TM}$ test. The percent of cell viability was measured into the culture medium collected after treatment of the pesticides for 24-72 hrs. The skin irritations of formulations were evaluated by the cell viability. In this study, The 4 formulations with mild irritation in rabbits were evaluated as nonirritant, the 6 formulations with moderate and severe irritation were evaluated as irritant in human skin model test. We suggest that the alternative test using Keraskin$^{TM}$ model could be used as toxicity evaluation for primary irritation index (P.I.I.) score of greater than or equal to 2.1 of pesticides. The further studies should be required to apply for hazardous assessment of pesticides on alternative skin irritation methods because of the interindividual variability of the sensitivity of skin irritation on pesticides.

• Journal of the Korean Society of Safety
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• v.31 no.6
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• pp.25-31
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• 2016

This paper has analyzed the structure, applicable regulations and the resistance characteristics of insulation ring type of CSST (Corrugated Stainless Steel Tubing for Gas). With the flammability test conducted in accordance with KS C IEC 60811-1-1, the evaluation of insulation resistance, temperature characteristics, and reliability has been conducted. An insulation ring type CSST consists of protective coating, tube, nut, insulation ring, packing, socket, and ball valve. Connecting an insulation ring type CSST to gas tubings for gas appliance is not permitted, moreover, the product shall be installed inside a sleeve pipe in case of buried installation such as the ceiling. Damages on protective coating and tube were detected when fire was applied to the test sample with a portable torch for 60 seconds. The insulation resistance of a normal product was $49.59M{\Omega}$, while that of the product completed the flammability test reduced to $9.21M{\Omega}$. The mean insulation resistance within the confidence Interval of 95% using the mini tap program 17 was $49.59M{\Omega}$ and the mean insulation resistance within the confidence interval reduced to $9.21M{\Omega}$. In the normal distribution analysis of 95% confidence interval, the value-P of the normal product was stable at 0.075 and AD(Anderson-Darling) statistic value was turned out to be 0.063, which is very normal, and the standard deviation was analyzed as 0.2586. The value P of the product completed the flammability test resulted in 0.005, the AD was 1.355 and the standard deviation reduced to 0.07908.

• Microbiology and Biotechnology Letters
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• v.49 no.1
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• pp.39-44
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• 2021

As consumption of healthy foods continues to garner remarkable public attention, ensuring probiotic safety has become a priority. In this study, the safety of Lactobacillus acidophilus IDCC 3302 was assessed in vitro and in vivo. L. acidophilus IDCC 3302 showed negative results for hemolytic and β-glucuronidase activities. The whole-genome analysis (WGA) revealed that L. acidophilus IDCC 3302 did not possess antibiotic resistance or virulence genes. The minimal inhibitory concentrations of L. acidophilus IDCC 3302 confirmed its safety concerning antibiotic resistance. Furthermore, L. acidophilus IDCC 3302 was demonstrated to be nontoxic in the oral toxicity test in rats. Therefore, the results suggested that L. acidophilus IDCC 3302 might be safe for human consumption.

• Journal of the Korean Society of Marine Environment & Safety
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• v.26 no.3
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• pp.277-285
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• 2020

Recently, studies have been actively conducted on seismic design and improvement of the seismic performance of bridges, buildings, factories, and plants. In particular, heavy items that are being manufactured or waiting to be shipped from factories (such as generators, engines, and boilers) must be equipped with seismic stoppers to prevent them from moving or falling during an earthquake. Seismic stoppers should be suitably determined by the size and weight of these heavy items; however, they have no general design standard. In this study, structural analyses and seismic tests were conducted to evaluate the performance of newly designed seismic stoppers. Structural analysis was performed on three stopper models to estimate the external load at which the yield stress of the material was not exceeded. Based on the analysis results, a seismic test of the stopper was carried out in accordance with the AC156 test method. Finally, product specifications for all three seismic stopper models were determined and their static/dynamic load performance was evaluated.

• Journal of Auto-vehicle Safety Association
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• v.12 no.3
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• pp.34-42
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• 2020

ADAS (Advanced Driver Assistance Systems) uses sensors such as camera, radar, lidar and GPS (Global Positioning System). Among these sensors, the camera has many advantages compared with other sensors. The reason is that it is cheap, easy to use and can identify objects. In this paper, therefore, a theoretical formula was proposed to obtain the distance from the vehicle's front wheel to the lane using a monocular camera. And the validity of the theoretical formula was verified through the actual vehicle test. The results of the actual vehicle test in scenario 4 resulted in a maximum error of 0.21 m. The reason is that it is difficult to detect the lane in the curved road, and it is judged that errors occurred due to the occurrence of significant yaw rates. The maximum error occurred in curve road condition, but the error decreased after lane return. Therefore, the proposed theoretical formula makes it possible to assess the safety of the LKA system.

• Transactions of the Korean Society of Mechanical Engineers
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• v.18 no.12
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• pp.3395-3403
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• 1994

The structural test technique and equipment for strength test of astronautical structures, such as rocket, were presented in this paper. Structural strength tests of the fin assembly with fin and fin frame in the scientific sound rocket were performed with load levels of 100% limit load and 150% ultimate load of design lift force. Safety factors in each part of the fin assembly were calculated at these two load levels and the stiffnesses based on the measured deflection of fin assembly and strains on fin and fin frame were evaluated at these two load level. As the result of structural test, the fin assembly was estimated to be safe.

• Transactions of the Korean Society of Automotive Engineers
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• v.13 no.6
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• pp.1-6
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• 2005

In domestic replacement tire market, imported tires are increasing condinuously. Because there is no institute officially investigating tire safety and performance, domestic drivers can be exposed to defective tires with no regulations. In this study we performed investigation of replacement tire market status and amount of imported tires. Over $90\%$ of imported tires are for passenger car and the number of total imported tires is increasing in recent years. Low price tires imported from Southeast Asia and China are selected to evaluate quality level. Basic inspection, indoor test, outdoor test, material test are conducted to evaluate the selected tires and compared with tires of domestic maker. From test results quality level of the selected tires could be found.

• Journal of the Korean Society of Safety
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• v.37 no.5
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• pp.1-6
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• 2022

In this study, to confirm the effects of the mixed load of normal and shear forces acting on a fixing bolt, fatigue design criteria were developed by varying the loading angle and conducting tensile and fatigue tests. After evaluating and comparing the test results under different loading angles, the evaluation criteria were selected. These evaluation criteria were then applied to develop the design criteria. An Arcan fixture was designed and manufactured to simultaneously apply a mixed load of normal and shear forces to the fixing bolt of a turntable, and a fatigue test was conducted. S-N diagrams for various loading angles were obtained, and a 1% P-S-N diagram of failure probability was determined using statistical processing techniques. Our results show that failures of the fixing bolt can be prevented using these diagrams as a basis for developing fatigue design criteria.

• Journal of the Korea Safety Management & Science
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• v.16 no.2
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• pp.31-42
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• 2014

As weapon systems become complex in terms of the scale and functionality, the required time to complete the test and evaluation (T&E) process is inevitably getting longer. However, nowadays the reduction of T&E period becomes one of the core targets in the weapon systems acquisition programs. This is because the reduced time for T&E process can yield the reduction of defense budget and also faster deployment of the weapon systems, thereby having a competitive edge over rival countries. On the other hand, in weapon systems development the management of reliability, availability, maintainability and safety (RAMS), and risk is considered important to keep competitiveness and thus has been carried out separately. Thus, the objective of this paper is to study on improving the T&E process by integrating the RAMS and risk management process in it. To do so, the related processes are analyzed and modeled first. Then an integrated process model is developed. The resulting model is equipped with the traceability among the data and interfaces that are generated from the T&E and RAMS/risk processes. As a case study, the model developed is applied in tanks development. The effective use of the traceability is expected to reduce the time and cost required to complete T&E process.

• Journal of the Korean Society of Safety
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• v.34 no.5
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• pp.31-36
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• 2019

This study made a testing device to evaluate the distribution board management system. Power was supplied to the testing device using a loading-back method and the voltage applied to it was 440 V at the same turn ratio. When the human body electric shock current is 30 mA, the breaking time is set to be less than 240 ms while 30~45 mA current is flowing. The test result shows that in the case of the R-phase it was measured to be 5.19 Hz (193 ms). And the S-phase and T-phase were perfectly cut off at 5.39 Hz (186 ms) and 5.71 Hz (175 ms), respectively. When the human body electric shock current is 60mA, the breaking time is set to be less than 120 ms while 45~75 mA current is flowing. The test result shows that the R-phase, S-phase, and T-phase were accurately cut off at 8.39 Hz (11 ms), 8.87Hz (113 ms) and 9.69 Hz (103 ms), respectively. When the human body electric shock current is 90 mA, the breaking time is set to be less than 48 ms while 75 mA current is flowing. The test result shows that the R-phase, S-phase, and T-phase were accurately cut off at 19.8 Hz (50.4 ms), 16.9 Hz (59.2 ms), and 17.9 Hz (56.0 ms), respectively. That is, the developed testing device satisfied all the requirements of the distribution board evaluation criteria, and it becomes available for the performance evaluation of the distribution board management system.