• Title/Summary/Keyword: Safety evaluation test

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A Study of the Endurance Severity for Automobile Wheel Safety Standard Revision (자동차 휠 안전기준 개정 대응을 위한 내구 가혹도 검토)

  • Jang, JinHee;Heo, SungPil
    • Journal of Auto-vehicle Safety Association
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    • v.14 no.3
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    • pp.30-34
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    • 2022
  • The CFT(Cornering Fatigue test) and RFT(Radial Fatigue Test) are tests for evaluating the endurance of the disc and rim region of the wheel. In recent, automobile wheel safety standards have been revised and the applied load and target life criteria are different from existing conditions. The verification evaluation of all wheels requires a lot of time and cost. In this study, the endurance severity of each test was compared through strain-life approach by selecting 4 steel and 8 aluminum wheels.

Evaluation of temperatures and flow areas of the Phebus Test FPT0

  • Koji Nishida;Naoki Sano;Seitaro Sakurai;Michio Murase
    • Nuclear Engineering and Technology
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    • v.56 no.3
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    • pp.886-892
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    • 2024
  • The cladding temperatures and axial mass distribution computed by MAAP5 were compared with their measured values in the test bundle of the Phebus Test FPT0. The computed cladding temperatures were in good agreed with the measured values in the pre-transient phase. In the transient heat-up phase, the computed temperatures were overestimated by the Baker-Just correlation in MAAP5, but the computed temperatures could simulate the subsequently measured values. The computed mass distribution in the axial direction was in qualitative agreement with the measured one for post-test fuel damage observations. The calculated flow areas of inner and outer regions in the test bundle were compared with the photographic observations. MAAP5 computed them at the height of 0.2 m where the molten pool formed was in qualitative agreement with the photographic observations. It was found that the remaining steam flow paths might be caused by the gas-liquid two-phase flow counter-current flow limitation.

Acute Ecotoxicity Evaluation of Environmental-friendly Organic Agro-materials Containing Pepper Extract, Cassia Oil, Lavender Oil for Control of Diamondbackmoth (배추좀나방 방제약제로서 후추 추출물, 카시아 오일, 라벤더 오일 함유 친환경유기농자재에 대한 급성 생태독성평가)

  • You, Are-Sun;Jeong, Mihye;Hong, Soon-Seong;Chang, Hee-Seop;Lee, Je Bong;Park, Kyung-Hun;Lee, Young Mook;Ihm, Yangbin
    • The Korean Journal of Pesticide Science
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    • v.17 no.4
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    • pp.343-349
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    • 2013
  • Environment-friendly agro-materials tend to be preferred to chemical insecticides recently. For this reason, many studies are conducted to develop environment-friendly insecticides containing natural materials. The purpose of this study was to assess ecotoxicity for pepper extract and cassia oil (11.5+46%, A), pepper extract and cassia oil (23+34%, B), and pepper extract and lavender oil (40+10%, C). They are expected to prevent from pests especially diamondback moth, and can be used for agro-materials. Their formulation was emusifiable concentration (EC). Target species used to assess acute toxicity were aquatic invertebrate (Daphina magna), fish (Cyprinus carpio), honeybee (Apis mellifera L.) and earthworm (Eisenia fetida). The $EC_{50}$ value of A, B, and C to aquatic invertebrate were 0.46, 1.9, 0.25 mg $L^{-1}$ respectively and these values were moderately toxic according to standard of USEPA. In case of acute toxicity test to fish, the $LC_{50}$ of A, B, and C were 1.9, 2.9, 3.8 mg $L^{-1}$ respectively. A was category II in acute toxicity of fish and not acceptable to evaluation criteria of environment-friendly agro-materials. B and C were category III and acceptable. Acute contact and oral toxicity test to honeybee were conducted and the $LD_{50}$ of A, B, and C were > 100 ${\mu}g$ a.i. $bee^{-1}$ in both of tests. It indicated they were low toxic to honeybee. In case of acute toxicity test to earthworm, $LC_{50}$ of A, B, and C were 695, 988, and 564 mg $kg^{-1}$. In conclusion, pepper extract+cassia oil 57% EC and pepper extract+lavender oil 50% EC were expected to be used for environment-friendly insecticide materials with low risk against ecosystem and contribute to developing environment-friendly agro-materials.

Risk Assesment for Large-scale Slopes Using Multiple Regression Analysis (다중회귀분석을 이용한 대규모 비탈면의 위험도 평가)

  • Lee, Jong-Gun;Chang, Buhm-Soo;Kim, Yong-Soo;Suk, Jae-Wook;Moon, Joon-Shik
    • Journal of the Korean Geotechnical Society
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    • v.29 no.11
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    • pp.99-106
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    • 2013
  • In this study, the correlation of evaluation items and safety rating for 104 of large-scale slopes along the general national road was analyzed. And, we proposed the regression model to predict the safety rating using the multiple regressions analysis. As the result, it is shown that the evaluation items of slope angle, rainfall and groundwater have a low correlation with safety rating. Also, the regression model suggested by multiple regression analysis shows high predictive value, and it would be possible to apply if the evaluation items of excavation condition and groundwater (rainfall) are not clear.

A Study on the Development of Traction Motor for Electric Railway: Insulation System Design & Performance Test

  • Wang, Jong-Bae
    • Transactions on Electrical and Electronic Materials
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    • v.2 no.4
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    • pp.19-23
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    • 2001
  • In this paper, design considerations and manufacturing procedure of 200 class insulation system with polyimide(Kapton) main insulation and silicone resin VPI process on the traction motor thor EMU will be reviewed. The performance test and the long life evaluation test that prove stability and reliability of Insulation system for traction motor will also be introduced.

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A Study on Toxicity Evaluation of Combustion Gases Released from the Residental Container Fire - Efficiency Test for the Fire Gas Mask Filters (주거용 컨테이너 화재시 발생되는 연소가스의 독성 평가에 관한 연구 - 화재용 방독면 filter의 성능평가를 중심으로)

  • Lee Jung Yun;Kim Jeong Hun;Kim Youn-Hi;Jung Ki Chang
    • Journal of the Korean Society of Safety
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    • v.19 no.4 s.68
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    • pp.48-54
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    • 2004
  • The recent Ire incident in an elementary school of Chonan city causes the media focus on the fire safety of residential container buildings. In this study, real fire tests were conducted in this kind of buildings. Combustion products including $O_2,\; CO_2,\;CO,\;NOx,\;SOx,\;HCI,\;HCN$ were measured, and blood samples of lab rats were analyzed in terms of Co-Hb, Glucose, AST(GOT), ALT(GPT), in order to investigate the hazard-reduction effects of employing gas mask protected with filter during the fire emergency of residential container buildings. According to the test results, whether or not employing the filter showed a sheer difference in the toxicity of the fire-induced gases, and then the importance of wearing a gas mask was evidently demonstrated.

Establishment of Dissolution Specifications for Generic Drugs in Korea Pharmaceutical Codex Monograph - Nicametate Citrate Tablet, Norfloxacin Capsule (고시 수재 의약품의 용출규격 설정 - 구연산니카메테이트 정, 노르플록사신 캡슐)

  • Kim, Hee-Yun;Choi, Seon-Hee;Bang, Su-Jin;Han, Kyung-Jin;Choi, Sung-Hee;Baek, Ji-Yun;Kim, Dong-Sup;Kim, Young-Ok;Sohn, Kyung-Hee;Song, Young-Me;Sah, Hong-Kee;Choi, Hoo-Kyun
    • YAKHAK HOEJI
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    • v.54 no.5
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    • pp.362-369
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    • 2010
  • Despite the fact that the dissolution test can serve as an effective tool for drug quality control and prediction of in vivo drug performance, there are a number of drugs with no established dissolution specifications because they were developed quite a long time ago. Under this circumstances, KFDA started the new project that establishes dissolution method and specifications for drugs with no dissolution specifications listed in the Korea Pharmaceutical Codex (KPC). This project aims for promoting the appropriate management of oral solid dosage forms. Seoul regional KFDA selected 2 items, Nicametate citrate tablet and Norfloxacin capsule, for establishing dissolution specifications. We went through the following procedures to develop the dissolution method and specifications: (1) Validation of dissolution test equipment, (2) Purchase of test drugs, (3) Preliminary test with one of the test products (1 lot), (4) Validation of analysis methods (3 lots), (5) Final tests and cross tests among other laboratory to establish dissolution specifications, (6) Additional test with the other test drugs. The outcome of this study will be reflected in revision of the KPC. It is believed that the quality control and evaluation of oral solid dosage forms listed in KPC will be advanced with the revision which adds additional dissolution test and specifications for the drugs with no established dissolution specifications.

A Case Study on Chloride Corrosion for the End Zone of Concrete Deck Subjected to De-icing Salts Added Calcium Chloride (염화칼슘이 함유된 제설제로 인한 콘크리트 바닥판 단부의 염해에 관한 사례 연구)

  • Chung, Jee-Seung;Kim, Bo-Heon;Kim, Il-Sun
    • Journal of the Korean Society of Safety
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    • v.29 no.6
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    • pp.87-93
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    • 2014
  • In this study, the reinforced concrete rahmen bridge damaged by the chloride attack was investigated. According to the investigation, the degraded concretes on cantilever kerb and end part were intensively observed. Thus, the chloride content test and half-cell method were performed to evaluate the degraded parts. As a result, the contents of chloride on degraded parts were C and D grade. On the other hand, the half-cell potential values of rebar in degraded concrete were measured with the minor corrosion. This rebar corrosion is expected to progressing. Chloride content D grade is due to expansion pressure by corrosion of rebar and freeze-thaw by permeate water, could see progresses rapidly degradation. In order to prevent chloride attack to concrete deck caused by deicing salts, corresponding to the chloride critical concentration must maintain grade b or at least grade c. Chloride condition evaluation standard apply to evaluation of marine structure chloride attack with chloride attack by deicing salts.

A Study on the Safety Evaluation of Design for Piping Materials (I) (배관용재료의 설계시 안전성 평가에 관한 연구(I))

  • 김복기
    • Journal of the Korean Society of Safety
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    • v.10 no.2
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    • pp.3-9
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    • 1995
  • Several piping material test methods have been developed as a result of advances in elastic-plastic fracture mechanics. It's known that, crack propagation of the materials strongly governed by the $J_{Ic}$ value. But the value is still difficult to be obtained because of it's complicate and troble-some determination process. In this paper, to prove the validity of the developed test procedure a series of tests were peformed at various temperatures and for different material directions. directions.

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Receptor Binding Affinities of Synthetic Cannabinoids Determined by Non-Isotopic Receptor Binding Assay

  • Cha, Hye Jin;Song, Yun Jeong;Lee, Da Eun;Kim, Young-Hoon;Shin, Jisoon;Jang, Choon-Gon;Suh, Soo Kyung;Kim, Sung Jin;Yun, Jaesuk
    • Toxicological Research
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    • v.35 no.1
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    • pp.37-44
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    • 2019
  • A major predictor of the efficacy of natural or synthetic cannabinoids is their binding affinity to the cannabinoid type I receptor ($CB_1$) in the central nervous system, as the main psychological effects of cannabinoids are achieved via binding to this receptor. Conventionally, receptor binding assays have been performed using isotopes, which are inconvenient owing to the effects of radioactivity. In the present study, the binding affinities of five cannabinoids for purified $CB_1$ were measured using a surface plasmon resonance (SPR) technique as a putative non-isotopic receptor binding assay. Results were compared with those of a radio-isotope-labeled receptor binding assay. The representative natural cannabinoid ${\Delta}^9$-tetrahydrocannabinol and four synthetic cannabinoids, JWH-015, JWH-210, RCS-4, and JWH-250, were assessed using both the SPR biosensor assay and the conventional isotopic receptor binding assay. The binding affinities of the test substances to $CB_1$ were determined to be (from highest to lowest) $9.52{\times}10^{-3}M$ (JWH-210), $6.54{\times}10^{-12}M$ (JWH-250), $1.56{\times}10^{-11}M$ (${\Delta}^9$-tetrahydrocannabinol), $2.75{\times}10^{-11}M$ (RCS-4), and $6.80{\times}10^{-11}M$ (JWH-015) using the non-isotopic method. Using the conventional isotopic receptor binding assay, the same order of affinities was observed. In conclusion, our results support the use of kinetic analysis via SPR in place of the isotopic receptor binding assay. To replace the receptor binding affinity assay with SPR techniques in routine assays, further studies for method validation will be needed in the future.