• Title/Summary/Keyword: Safety Importance and Significance

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A study on performance-based evaluation system for NATM tunnels in use: development of evaluation model and validation (공용중인 NATM 터널의 성능중심 평가체계 연구: 평가모형 개발 및 검증)

  • Moon, Joon-Shik;Kim, Hong-Kyoon;An, Jai-Wook;Lee, Jong-Gun
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.22 no.1
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    • pp.107-120
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    • 2020
  • In a performance-based evaluation of structures in use, the current performance is assessed by summing up the weighting of the evaluation indices for each performance. In this study, to suggest a performance-based evaluation technique for NATM tunnels in use, the performance evaluation indices were derived by examining the characteristics and similarities of each index developed from previous study. The weighting of the evaluation indices was derived by calculating the relative importance of each evaluation indices from the AHP analysis. In order to develop a quantitative evaluation model, grading criteria for each performance index was derived through literature review, and performance evaluation tables for road and railway tunnels were presented. In order to verify the significance of the proposed performance evaluation model, the correlation analysis was performed between each evaluation index and the final evaluation result. In the correlation analysis, the survey data measured through precision safety diagnosis in the tunnel in use was applied. It may be said that the proposed evaluation indices, weighting, criteria and evaluation models for tunnels in use can be applied to the performance-based maintenance system of tunnels.

Avantor® ACE® Wide Pore HPLC Columns for the Separation and Purification of Proteins in Biopharmaceuticals (바이오의약품의 단백질 분리 및 정제를 위한 Avantor® ACE® 와이드 포어 HPLC 컬럼 가이드)

  • Matt James;Mark Fever;Tony Edge
    • FOCUS: LIFE SCIENCE
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    • no.1
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    • pp.3.1-3.7
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    • 2024
  • The article discusses the critical role of chromatography in the analysis and purification of proteins in biopharmaceuticals, emphasizing the importance of comprehensive characterization for ensuring their safety and efficacy. It highlights the use of Avantor® ACE® HPLC columns for the separation and purification of proteins, focusing on the analysis of intact proteins using reversed-phase liquid chromatography (RPLC) with fully porous particles. This article also details the application of different mobile phase additives, such as TFA and formic acid, and emphasizes the advantages of using type B ultra-pure silica-based columns for efficiency and peak shape in biomolecule analysis. Additionally, it addresses the challenges of analyzing intact proteins due to slow molecular diffusion and introduces the concept of solid-core (or superficially porous) particles, emphasizing their benefits over traditional porous particles for the analysis of therapeutic proteins. Furthermore, it discusses the development of Avantor® ACE® UltraCore BIO columns, specifically designed for the high-efficiency separation of large biomolecules, such as proteins, and demonstrates their effectiveness in achieving high-resolution separations, even for higher molecular weight proteins like monoclonal antibodies (mAbs). In addition, it underscores the complexity of analyzing and characterizing intact protein biopharmaceuticals, requiring a range of analytical techniques and the use of wide-pore stationary phases, operated at elevated temperatures and with relatively shallow gradients. It highlights the comprehensive range of options offered by Avantor® ACE® wide pore columns, including both fully porous and solid-core particles, bonded with a variety of complementary stationary phase chemistries to optimize selectivity during method development. The use of ultrapure and highly inert base silica is emphasized for enabling the use of lower concentrations of mobile phase modifiers without compromising analyte peak shape, particularly beneficial for LC-MS applications. Then the article concludes by emphasizing the significance of reversed-phase liquid chromatography and its compatibility with mass spectrometry as a valuable tool for the separation and analysis of intact proteins and their closely related variants in biopharmaceuticals.

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Analysis of Satisfaction on Alley Garden's Components through Urban Regeneration - Focused on Bisan 2·3-dong in Daegu Metropolitan City - (도시재생사업에 따른 골목정원 구성요소의 만족도 분석 - 대구광역시 비산 2·3동을 대상으로 -)

  • Jang, Cheol-Kyu;Hwang, Myeong-Lan;Shin, Jae-Yun;Jung, Sung-Gwan
    • Journal of the Korean Institute of Landscape Architecture
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    • v.45 no.6
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    • pp.137-148
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    • 2017
  • This study analyzed the opinions of residents for desirable urban regeneration and suggested an improvement plan for alley environments. This study conducted a questionnaire survey of the residents living in Alley Garden of Bisan 2,3-dong, Daegu Metropolitan City. In the analysis of the importance and satisfaction of Alley Garden components, items related to a safe, cleanly environment such as 'Lighting facility installation', 'Sewage and waste disposal' and 'CCTV installation' had a high level of importance. It was also found that items improved by the Residential Environment Improvement Project and Alley Garden such as 'Lighting facility installation', 'Quantity of herbaceous flowers' and 'Kinds of herbaceous flowers' had a high level of satisfaction. The IPA results showed that items such as 'Empty house maintenance', 'Rest facilities such as benches and pergolas', 'Space for resident interaction' and 'Public parking lot' had a high level of importance, but had a low level of satisfaction, which suggests that they should be improved by priority. As a result of factor analysis, Alley Garden components were classified into four factors: 'Safety and cleanliness', 'Greenness', 'Exchange and convenience facility' and 'Aesthetics renewal'. Based on this classification, a regression analysis was conducted regarding the effects of the four factors on overall satisfaction. Results showed that all four factors had a significant influence on the overall satisfaction and that 'Aesthetics renewal' and 'Safety and cleanliness', respectively showing levels of significance at 0.274 and 0.235, were highly influential to overall satisfaction. Therefore, it was concluded that spaces for resident interaction and rest facilities should be preferentially installed to improve the environment of alleys. For the improvement of the overall satisfaction of alley environments, it was also concluded that residents should be encouraged to engage in activities such as sculpture installation and mural drawing, along with the introduction of safety bells and crime prevention environment design and the implementation of alley beautification projects.

Highest Value Shown in Baekbun (白粉, Face Powder) Advertisement Texts from the 1920s to the 1930s -Focus on a Transitional Confrontation between Traditional Beauty and Modern Beauty- (1920~1930년대 백분 광고 텍스트에 나타난 최상의 가치 -전통미와 근대미의 과도기적 대립을 중심으로-)

  • Baek, Ju Hyun;Chae, Keum Seok;Kim, So hee
    • Journal of the Korean Society of Clothing and Textiles
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    • v.42 no.3
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    • pp.544-559
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    • 2018
  • Korea's traditional aesthetic criterion changed with a new makeup culture that followed the social change caused by modernization. Such transitional features are well seen in the cosmetic advertisements of the 1920's and 1930's. To investigate the cultural characteristics and aesthetic-criteria changes of makeup culture at this period, this thesis analyzes cosmetic advertisements carried in newspaper media of the 1920's and 1930's from an aesthetic perspective. This study found that after the late 1920's, more diverse tones were used for face-powder makeup, collapsing the visual, powder-focused makeup which had been considered criteria for beauty, in combination with smelling and tactile senses such as scent or touch. Domestic makeup had the highest value attached to basic skincare in terms of the aesthetic effect via powder makeup; however, Japanese makeup still stressed the importance of color. Besides, particular facts were found as to social significance of makeup acts such as powder users' age group, safety, superiority and rivals of products, and appeal for makeup popularization. This thesis demonstrates how traditional female beauty appears in powder advertisements in the modern period and how it is related to present-day female beauty.

An Analysis of Construction Execution Tasks for Successful Residential Mechanical Projects (프로젝트 성공을 위한 효과적인 시공업무 및 영향 분석 - 아파트 설비공사를 중심으로 -)

  • Kang, Sang-Hun;Kim, Dae Young
    • Korean Journal of Construction Engineering and Management
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    • v.20 no.2
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    • pp.60-67
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    • 2019
  • The main purpose of this study is to identify the tasks performed at the construction stage of apartment houses and analyze the major construction tasks that may affect the performance indicators and analyze the impact on project performance. Based on expert opinions through preliminary research, pilot data, construction database, and other research trends, domestic and foreign research trends are divided into five major tasks, and each is divided into process management (P'1 ~ P'6), construction management (C'1 ~ C'5), environmental management (E'1 ~ E'4), quality control (Q'1 ~ Q'5), safety management (S'1 ~ S'5). Subsequently, each major task was subdivided into 24 detailed tasks. An independent t-test was conducted to analyze the impact on cost. We compared the importance of achieving the project goal and identified the construction work of concrete important construction which affects not only the cost but also the schedule performance index for the degree of significance of less than 0.05.

A Research on the Transference of Trust from Service Provider to MyData Banking Service (서비스 제공 기업에 대한 신뢰가 금융 마이데이터 서비스에 전이되는 현상에 관한 연구)

  • Ah Ro Kum;Jung Hoon Lee;Yun A Yeo
    • Journal of Information Technology Services
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    • v.23 no.1
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    • pp.97-121
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    • 2024
  • As data usage grows in importance, ensuring individual control over personal information becomes critical. The emergence of the 'MyData' concept addresses this, particularly in financial services. Although the institutional and technological framework for financial MyData services is in place, there's a need to establish consumer understanding and perception of its usefulness and safety for successful activation. This study focuses on investigating the impact of trust on the intention to use the new mobile banking service, financial MyData. This study has three objectives. Firstly, to analyze whether trust in financial MyData services and trust in financial MyData service providers affect the intention to use financial MyData services. Secondly, to analyze the process of forming trust in financial MyData services based on the phenomenon of transferring trust in service providers to trust in services. Thirdly, to identify the process by which trust transfer occurs between service providers and financial MyData services. Ultimately, the goal of this study is to promote the intention to use financial MyData services based on the concept of trust and to activate these services. In summary, this study emphasizes the significance of trust in financial MyData services, exploring its impact on user intention and the transfer of trust from providers to services. By promoting consumer trust, the research aims to contribute to the activation of financial MyData services.

The Effects of Family Ties on Suicidal Ideation of the Rural Elderly in Korea - Focused on the Meditating Effects of Community Consciousness - (가족유대감이 농촌 노인의 자살 생각에 미치는 영향 - 마을공동체 의식의 매개효과를 중심으로 -)

  • Lee, Boram;Lee, Jeonghwa
    • Korean Journal of Human Ecology
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    • v.24 no.6
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    • pp.795-809
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    • 2015
  • The suicide rate in South Korea has been the highest among the OECD countries for more than 10 years. In addition, the suicide rate among the rural elderly is much higher than that of the elderly in urban areas and that of younger generations. The purpose of this study was to examine the general tendencies of family ties, community consciousness and suicide ideation of the rural elderly in Korea. Also, this study aimed to verify the mediating effect of community consciousness between family ties and suicidal ideation. The data for this study came from 283 elderly people (over 65 years old) living in 11 villages in South Korea. The data was gathered from July to August 2013. Baron and Kenny's (1986) step based regression from the SPSS Win 18.0 program was used to analyze this data. This study also utilized the Sobel-test. The results of this study are as follows. First, the suicidal ideation of the respondents had a lower score than the median score. However, the magnitude of suicidal ideation was still significant. Second, this study found that family ties and community consciousness have both direct and indirect effects on the reduction of suicidal ideation. Lastly, this study examined the mediating effects of community consciousness. The findings of this study are of great significance because they reconfirmed the importance of establishing a social safety net in local communities to replace adult children who have relocated to urban areas.

Usage and Dosage of Ginseng Radix (panax ginseng C. A. Meyer) Based upon Traditional and Recent Scientific Clinical Applications (인삼의 한의학적 및 현대임상적 측면에서의 복용량 검토)

  • 남기열;박종대
    • Journal of Ginseng Research
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    • v.24 no.2
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    • pp.99-105
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    • 2000
  • Ginsenf Radix (Panax ginseng C. A. Meyer) has been traditionally used as a herbal medicine for many therapeutic or prophylactic purposes in the oriental countries such as Korea, Japan and China for at least two thousand years and also extensively studied in the modern scientific field of chemistry, biochemistry and pharmacology. The herb is now also indicated for use as tonic or a prophylactic and restorative agent for enhancement of mental and physical capacities, in case of weahess exhaustion tiredness loss of concentration, impotence, cold limbs, during illiness anuor convalescence. Ginseng is commonly used in the form of detections, extract and powderl and ginseng products, in the form of capsules tablets and drinks. And also ginseng radix has been widely traditionally prescribed as an important comuonents of manny Chinese prescriptions or alone in various diseases and for health with its different dosages. Nowadays since rinsenf can be generally classified into food or medicine in many nations, it is very difficult to give any exact desnition on the dosage, which may be of particular importance in clinical applications. In addition, the establishment of the reasonable dosage is currently of great significance to meet the demand for such wide applications. Accordingly in this review paper we summarized the dosage of ginseng on the basis of oriental medical books oriental and western pharmacopeias and modern scientific clinical data. The recent survey demonstrated that the averare dosare of finsenf is considered to be three to four grams per day unless prescribed apart, while one to two grams per day in western countries from the western viewpoint of classification of ginseng as a medicine, surrorted by the dosage of not more than one gram per day in most clinical studies. For that reason, it seems likely that the dosage in western countries is ascribed to the safety of ginseng considering side or unwanted effects. Consequently whether the differences of dosage between oriental and western countries depend on dietary habits and races should be closely investigated. Besides, further studies on the pharmacokinetics and bioavailability of ginseng components in clinical trials need to be done to decide optimum dosage of ginseng.

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Economic Analysis of Intelligent Security Service for Crime Prevention :Focused on Anyang City Security Demonstration District Project (범죄예방을 위한 지능형 방범 서비스 도입에 따른 경제성 분석 연구 :안양시 방범 실증지구 사업을 중심으로)

  • Yu, In-Jae;Han, Sun-Hee;Shin, Young-Seob;Lee, Jae-Yong
    • The Journal of the Korea Contents Association
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    • v.19 no.8
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    • pp.667-676
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    • 2019
  • In recent years, the occurrence of life and violent crime in the city centered on crime-prone areas has become a big issue, raising the public interest in safety from crime has been higher than ever. As the initial response to crime and the importance of crime prevention are emerging, the government is preparing various measures such as crime prevention service using advanced technology. This project is a demonstration project to select specific target sites and apply that on a trial basis with the main purpose of commercialization of intelligent crime prevention technologies and services. In order to spread the business through the demonstration project, it is expected that the practical economic evaluation as well as the academic and practical value of the project will have a great significance. In this study, the purpose of this research is to derive economic feasibility through technologies and services to be implemented in Indokwon district of Anyang city, which is selected demonstration site of the intelligent security, to promote the spread of business and contribute to the policy activation.

A Study on Middle School Student Users' Perceptions of Spatial Characteristics of School Libraries as Reading Spaces (독서공간으로서 학교도서관 공간특성 요소에 대한 중학생 이용자 인식에 관한 연구)

  • Munji Jeong;Jee Yeon Lee
    • Journal of the Korean Society for information Management
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    • v.40 no.4
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    • pp.229-257
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    • 2023
  • This study aims to understand students' perceptions of the spatial characteristics of school libraries when they use them for reading. We selected a set of spatial characteristics by reviewing the literature and conducting a preliminary investigation. Then, we examined how students perceived the importance of and how satisfied they were with each characteristic. In addition, we investigated how students' perceptions differ by the library uses and reading-related activities. We also studied whether the satisfaction of school library users affects their continued use of the libraries. We also verified whether school library user satisfaction is an intervening variable in continued-use intention, which is affected by spatial characteristics perception. We conducted a survey of 342 students from four middle schools. The analysis of the survey outcomes shows differences in library use due to spatial characteristics such as convenience, communicability, diversity, and safety. Factors such as communicability, comfortability, and ambience affected user satisfaction positively. Both aesthetics and communicability also positively influenced the continued-use intention. Furthermore, we identified that communicability, comfortability, and ambience eventually impacted the continued-use intention via user satisfaction, an intervening variable. The significance of this study is that it considered the direction of the school library to support students' reading by regarding the school library as a space for reading.