• Title/Summary/Keyword: SVM Model

Search Result 698, Processing Time 0.023 seconds

Computational Analysis of the 3-D structure of Human GPR87 Protein: Implications for Structure-Based Drug Design

  • Rani, Mukta;Nischal, Anuradha;Sahoo, Ganesh Chandra;Khattri, Sanjay
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.14 no.12
    • /
    • pp.7473-7482
    • /
    • 2013
  • The G-protein coupled receptor 87 (GPR87) is a recently discovered orphan GPCR which means that the search of their endogenous ligands has been a novel challenge. GPR87 has been shown to be overexpressed in squamous cell carcinomas (SCCs) or adenocarcinomas in lungs and bladder. The 3D structure of GPR87 was here modeled using two templates (2VT4 and 2ZIY) by a threading method. Functional assignment of GPR87 by SVM revealed that along with transporter activity, various novel functions were predicted. The 3D structure was further validated by comparison with structural features of the templates through Verify-3D, ProSA and ERRAT for determining correct stereochemical parameters. The resulting model was evaluated by Ramachandran plot and good 3D structure compatibility was evidenced by DOPE score. Molecular dynamics simulation and solvation of protein were studied through explicit spherical boundaries with a harmonic restraint membrane water system. A DRY-motif (Asp-Arg-Tyr sequence) was found at the end of transmembrane helix3, where GPCR binds and thus activation of signals is transduced. In a search for better inhibitors of GPR87, in silico modification of some substrate ligands was carried out to form polar interactions with Arg115 and Lys296. Thus, this study provides early insights into the structure of a major drug target for SCCs.

Comparison of data mining methods with daily lens data (데일리 렌즈 데이터를 사용한 데이터마이닝 기법 비교)

  • Seok, Kyungha;Lee, Taewoo
    • Journal of the Korean Data and Information Science Society
    • /
    • v.24 no.6
    • /
    • pp.1341-1348
    • /
    • 2013
  • To solve the classification problems, various data mining techniques have been applied to database marketing, credit scoring and market forecasting. In this paper, we compare various techniques such as bagging, boosting, LASSO, random forest and support vector machine with the daily lens transaction data. The classical techniques-decision tree, logistic regression-are used too. The experiment shows that the random forest has a little smaller misclassification rate and standard error than those of other methods. The performance of the SVM is good in the sense of misclassfication rate and bad in the sense of standard error. Taking the model interpretation and computing time into consideration, we conclude that the LASSO gives the best result.

Hypergraph model based Scene Image Classification Method (하이퍼그래프 모델 기반의 장면 이미지 분류 기법)

  • Choi, Sun-Wook;Lee, Chong Ho
    • Journal of the Korean Institute of Intelligent Systems
    • /
    • v.24 no.2
    • /
    • pp.166-172
    • /
    • 2014
  • Image classification is an important problem in computer vision. However, it is a very challenging problem due to the variability, ambiguity and scale change that exists in images. In this paper, we propose a method of a hypergraph based modeling can consider the higher-order relationships of semantic attributes of a scene image and apply it to a scene image classification. In order to generate the hypergraph optimized for specific scene category, we propose a novel search method based on a probabilistic subspace method and also propose a method to aggregate the expression values of the member semantic attributes that belongs to the searched subsets based on a linear transformation method via likelihood based estimation. To verify the superiority of the proposed method, we showed that the discrimination power of the feature vector generated by the proposed method is better than existing methods through experiments. And also, in a scene classification experiment, the proposed method shows a competitive classification performance compared with the conventional methods.

Real-Time Eye Detection and Tracking Under Various Light Conditions (다양한 조명하에서 실시간 눈 검출 및 추적)

  • 박호식;박동희;남기환;한준희;나상동;배철수
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
    • /
    • 2003.10a
    • /
    • pp.227-232
    • /
    • 2003
  • Non-intrusive methods based on active remote IR illumination for eye tracking is important for many applications of vision-based man-machine interaction. One problem that has plagued those methods is their sensitivity to lighting condition change. This tends to significantly limit their scope of application. In this paper, we present a new real-time eye detection and tracking methodology that works under variable and realistic lighting conditions. eased on combining the bright-pupil effect resulted from IR light and the conventional appearance-based object recognition technique, our method can robustly track eyes when the pupils are not very bright due to significant external illumination interferences. The appearance model is incorporated in both eyes detection and tracking via the use of support vector machine and the mean shift tracking. Additional improvement is achieved from modifying the image acquisition apparatus including the illuminator and the camera.

  • PDF

Design of Anomaly Detection System Based on Big Data in Internet of Things (빅데이터 기반의 IoT 이상 장애 탐지 시스템 설계)

  • Na, Sung Il;Kim, Hyoung Joong
    • Journal of Digital Contents Society
    • /
    • v.19 no.2
    • /
    • pp.377-383
    • /
    • 2018
  • Internet of Things (IoT) is producing various data as the smart environment comes. The IoT data collection is used as important data to judge systems's status. Therefore, it is important to monitor the anomaly state of the sensor in real-time and to detect anomaly data. However, it is necessary to convert the IoT data into a normalized data structure for anomaly detection because of the variety of data structures and protocols. Thus, we can expect a good quality effect such as accurate analysis data quality and service quality. In this paper, we propose an anomaly detection system based on big data from collected sensor data. The proposed system is applied to ensure anomaly detection and keep data quality. In addition, we applied the machine learning model of support vector machine using anomaly detection based on time-series data. As a result, machine learning using preprocessed data was able to accurately detect and predict anomaly.

Discriminant analysis of grain flours for rice paper using fluorescence hyperspectral imaging system and chemometric methods

  • Seo, Youngwook;Lee, Ahyeong;Kim, Bal-Geum;Lim, Jongguk
    • Korean Journal of Agricultural Science
    • /
    • v.47 no.3
    • /
    • pp.633-644
    • /
    • 2020
  • Rice paper is an element of Vietnamese cuisine that can be used to wrap vegetables and meat. Rice and starch are the main ingredients of rice paper and their mixing ratio is important for quality control. In a commercial factory, assessment of food safety and quantitative supply is a challenging issue. A rapid and non-destructive monitoring system is therefore necessary in commercial production systems to ensure the food safety of rice and starch flour for the rice paper wrap. In this study, fluorescence hyperspectral imaging technology was applied to classify grain flours. Using the 3D hyper cube of fluorescence hyperspectral imaging (fHSI, 420 - 730 nm), spectral and spatial data and chemometric methods were applied to detect and classify flours. Eight flours (rice: 4, starch: 4) were prepared and hyperspectral images were acquired in a 5 (L) × 5 (W) × 1.5 (H) cm container. Linear discriminant analysis (LDA), partial least square discriminant analysis (PLSDA), support vector machine (SVM), classification and regression tree (CART), and random forest (RF) with a few preprocessing methods (multivariate scatter correction [MSC], 1st and 2nd derivative and moving average) were applied to classify grain flours and the accuracy was compared using a confusion matrix (accuracy and kappa coefficient). LDA with moving average showed the highest accuracy at A = 0.9362 (K = 0.9270). 1D convolutional neural network (CNN) demonstrated a classification result of A = 0.94 and showed improved classification results between mimyeon flour (MF)1 and MF2 of 0.72 and 0.87, respectively. In this study, the potential of non-destructive detection and classification of grain flours using fHSI technology and machine learning methods was demonstrated.

Simultaneous Optimization Model of Case-Based Reasoning for Effective Customer Relationship Management (효과적인 고객관계관리를 위한 사례기반추론 동시 최적화 모형)

  • Ahn, Hyun-Chul;Kim, Kyoung-Jae;Han, In-Goo
    • Journal of Intelligence and Information Systems
    • /
    • v.11 no.2
    • /
    • pp.175-195
    • /
    • 2005
  • 사례기반추론(case-based reasoning)은 사례간 유사도를 평가하여 유사한 이웃사례를 찾아내고, 이웃사례의 결과를 이용하여 새로운 사례에 대한 예측결과를 생성하는 전통적인 인공지능기법 중 하나다. 이러한 사례기반추론이 최근 적용이 쉽고 간단하다는 장점과 모형의 갱신이 실시간으로 이루어진다는 점 등으로 인해, 온라인 환경에서의 고객관계관리를 위한 도구로 학계와 실무에서 주목을 받고 있다 하지만, 전통적인 사례기반추론의 경우, 타 인공지능기법에 비해 정확도가 상대적으로 크게 떨어진다는 점이 종종 문제점으로 제기되어 왔다. 이에, 본 연구에서는 사례기반추론의 성과를 획기적으로 개선하기 위한 방법으로 유전자 알고리즘을 활용한 사례기반추론의 동시 최적화 모형을 제안하고자 한다. 본 연구가 제안하는 모형에서는 기존 연구에서 사례기반추론의 성과에 중대한 영향을 미치는 요소들로 제시된 바 있는 사례 특징변수의 상대적 가중치 선정(feature weighting)과 참조사례 선정(instance selection)을 유전자 알고리즘을 이용해 최적화함으로서, 사례간 유사도를 보다 정밀하게 도출하는 동시에 추론의 결과를 왜곡할 수 있는 오류사례의 영향을 최소화하고자 하였다. 제안모형의 유용성을 검증하기 위해, 본 연구에서는 국내 한 전문 인터넷 쇼핑몰의 구매예측모형 구축사례에 제안모형을 적용하여 그 성과를 살펴보았다. 그 결과, 제안모형이 지금까지 기존 연구에서 제안된 다른 사례기반추론 개선모형들은 물론, 로지스틱 회귀분석(LOGIT), 다중판별분석(MDA), 인공신경망(ANN), SVM 등 다른 인공지능 기법들에 비해서도 상대적으로 우수한 성과를 도출할 수 있음을 확인할 수 있었다.

  • PDF

GP Modeling of Nonlinear Electricity Demand Pattern based on Machine Learning (기계학습 기반 비선형 전력수요 패턴 GP 모델링)

  • Kim, Yong-Gil
    • The Journal of the Institute of Internet, Broadcasting and Communication
    • /
    • v.21 no.3
    • /
    • pp.7-14
    • /
    • 2021
  • The emergence of the automated smart grid has become an essential device for responding to these problems and is bringing progress toward a smart grid-based society. Smart grid is a new paradigm that enables two-way communication between electricity suppliers and consumers. Smart grids have emerged due to engineers' initiatives to make the power grid more stable, reliable, efficient and safe. Smart grids create opportunities for electricity consumers to play a greater role in electricity use and motivate them to use electricity wisely and efficiently. Therefore, this study focuses on power demand management through machine learning. In relation to demand forecasting using machine learning, various machine learning models are currently introduced and applied, and a systematic approach is required. In particular, the GP learning model has advantages over other learning models in terms of general consumption prediction and data visualization, but is strongly influenced by data independence when it comes to prediction of smart meter data.

Data Analysis of Dropouts of University Students Using Topic Modeling (토픽모델링을 활용한 대학생의 중도탈락 데이터 분석)

  • Jeong, Do-Heon;Park, Ju-Yeon
    • Journal of the Korea Institute of Information and Communication Engineering
    • /
    • v.25 no.1
    • /
    • pp.88-95
    • /
    • 2021
  • This study aims to provide implications for establishing support policies for students by empirically analyzing data on university students dropouts. To this end, data of students enrolled in D University after 2017 were sampled and collected. The collected data was analyzed using topic modeling(LDA: Latent Dirichlet Allocation) technique, which is a probabilistic model based on text mining. As a result of the study, it was found that topics that were characteristic of dropout students were found, and the classification performance between groups through topics was also excellent. Based on these results, a specific educational support system was proposed to prevent dropout of university students. This study is meaningful in that it shows the use of text mining techniques in the education field and suggests an education policy based on data analysis.

Damaged cable detection with statistical analysis, clustering, and deep learning models

  • Son, Hyesook;Yoon, Chanyoung;Kim, Yejin;Jang, Yun;Tran, Linh Viet;Kim, Seung-Eock;Kim, Dong Joo;Park, Jongwoong
    • Smart Structures and Systems
    • /
    • v.29 no.1
    • /
    • pp.17-28
    • /
    • 2022
  • The cable component of cable-stayed bridges is gradually impacted by weather conditions, vehicle loads, and material corrosion. The stayed cable is a critical load-carrying part that closely affects the operational stability of a cable-stayed bridge. Damaged cables might lead to the bridge collapse due to their tension capacity reduction. Thus, it is necessary to develop structural health monitoring (SHM) techniques that accurately identify damaged cables. In this work, a combinational identification method of three efficient techniques, including statistical analysis, clustering, and neural network models, is proposed to detect the damaged cable in a cable-stayed bridge. The measured dataset from the bridge was initially preprocessed to remove the outlier channels. Then, the theory and application of each technique for damage detection were introduced. In general, the statistical approach extracts the parameters representing the damage within time series, and the clustering approach identifies the outliers from the data signals as damaged members, while the deep learning approach uses the nonlinear data dependencies in SHM for the training model. The performance of these approaches in classifying the damaged cable was assessed, and the combinational identification method was obtained using the voting ensemble. Finally, the combination method was compared with an existing outlier detection algorithm, support vector machines (SVM). The results demonstrate that the proposed method is robust and provides higher accuracy for the damaged cable detection in the cable-stayed bridge.