• Korean Journal of Head & Neck Oncology
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• v.32 no.1
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• pp.13-19
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• 2016

Background : The 2015 American thyroid association (ATA) guidelines greatly expanded section on risk stratification of thyroid cancer. Definition of "Low risk of recurrence" has expanded, by inclusion of small volume lymph node involvement, such as less than 5 lymph node metastases each smaller than 2mm in central compartment. Purpose : We evaluated the number of positive nodes, Positive node ratio (PNR), recurrence, and radioablation therapy. Also, evaluated the safety of omitting strategy of radioablation after total thyroidectomy with PTC, especially on low-PNR N1a patients compared with high-PNR N1a patients. Methods : Consecutive 147 N1a and 216 N0 patients who underwent total thyroidectomy with central neck dissection between 2003 and 2004 were enrolled. We divided 147 N1a patients into two groups, such as 96 high-PNR versus 51 low-PNR group according to 50% of PNR, and compared these two groups with N0 group. Results: 7.2% (26/363) recurrences were occurred, and 21/147 (14.3 %) recurrences were on N1a patients, and 5/216 (2.3 %) were on N0 patients. Of these 21 recurrences in N1a stage patients, 20 (95.2 %) recurrences were occurred in high-PNR N1a group and only 1 (4.8 %) recurrence was in low-PNR N1a group. The recurrence of low-PNR N1a group was significantly lower than high-PNR N1a group (Log-rank p value = 0.003), but significantly not different from N0 group (Log-rank p value = 0.889). Although this study was a retrospective non-randomized trial with small number of patients, the 10-year recurrence of omitting RAI in low-PNR N1a patients with less than 50% of PNR were shown to be comparable with 216 N0 low risk patients. Conclusion : Positive node ratio could be a useful predictor of recurrence and useful guidance postoperative management -rather than absolute number of positive node.

• Journal of Energy Engineering
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• v.23 no.4
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• pp.95-105
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• 2014

The CUPID code has been developed for a transient, three-dimensional, two-phase flow analysis at a component scale. It has been validated against a wide range of two-phase flow experiments. Especially, to assess its applicability to single- and two-phase flow analyses in the Calandria vessel of a CANDU nuclear reactor, it was validated using the experimental data of the 1/4-scaled facility of a Calandria vessel at the STERN laboratory. In this study, a preliminary thermal-hydraulic analysis of the CANDU reactor moderator tank using the CUPID code is carried out, which is based on the results of the previous studies. The complicated internal structure of the Calandria vessel and the inlet nozzle was modeled in a simplified manner by using a porous media approach. One of the most important factors in the analysis was found to be the modeling of the tank inlet nozzle. A calculation with a simple inlet nozzle modeling resulted in thermal stratification by buoyance, leading to a boiling from the top of the Calandria tank. This is not realistic at all and may occur due to the lack of inlet flow momentum. To improve this, a new nozzle modeling was used, which can preserve both mass flow and momentum flow at the inlet nozzle. This resulted in a realistic temperature distribution in the tank. In conclusion, it was shown that the CUPID code is applicable to thermal-hydraulic analysis of the CANDU reactor moderator tank using the cost-effective porous media approach and that the inlet nozzle modeling is very important for the flow analysis in the tank.

• The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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• v.16 no.4
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• pp.155-168
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• 2011

Coastal boundary current flows along the eastern boundary of the Yellow Sea and its speed was about 0.l m/s during the summer 2007. In order to find major factors that affect the coastal boundary current in the eastern Yellow Sea, three-dimensional numerical model experiments were performed. The model simulation results were validated against hydrographic and current meter data in the eastern Yellow Sea. The eastern boundary current flows along the bottom front over the upper part of slopping bottom. Strength and position of the current were affected by tides, winds, local river discharge, and solar radiation. Tidal stirring and surface wind mixing were major factors that control the summertime boundary currents along the bottom front. Tidal stirring was essential to generate the bottom temperature front and boundary current. Wind mixing made the boundary current wider and augmented its north-ward transport. Buoyancy forcing from the freshwater input and solar radiation also affected the boundary current but their contributions were minor. Strong (weak) tidal mixing during spring (neap) tides made the northward transport larger (smaller) in the numerical simulations. But offshore position of the eastern boundary current's major axis was not apparently changed by the spring-neap cycle in the mid-eastern Yellow Sea due to strong summer stratification. The mean position of coastal boundary current varied due to variations in the level of wind mixing.

• Korean Journal of Social Welfare
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• v.65 no.3
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• pp.29-52
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• 2013

This study examined how middle-aged and elderly persons allocated their time in overall perspective and whether the patterns were varied by age, socio-demographic factors, and the interaction effect between them. This study analyzed the 2009 Time Use Survey Data (17,096 time-diaries of people aged 45 or more) of the National Statistical Office using tobit regression model. The main results are as follows. First, middle-aged and elderly people gradually decreased paid work times. Second, the patterns of time allocation were varied by age, gender, education level, marital status and household type(Agricultural/non-agricultural). Third, there were interaction effects between age and the socio-demographic factors on paid work time and leisure time. Highly educated or urban persons were likely to have less time in paid work less than other groups with increasing age. And females were likely to have less time in domestic labor and care work than males with increasing age. But they had more time in social and economic productive activities than males. Based on these findings, this study suggests comprehensive approach to analyze the time use of elderly beyond economic working time or leisure time. To establish effective ageing society policy, it is necessary to consider the time allocation of elderly which divided into the social stratification.

• Journal of Korean Society of Forest Science
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• v.101 no.4
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• pp.547-557
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• 2012

This study purposed to estimate the forest biomass using k-Nearest Neighbor (k-NN) algorithm. Multiple data sources were used for the analysis such as forest type map, field survey data and Landsat TM data. The accuracy of forest biomass was evaluated with the forest stratification, horizontal reference area (HRA) and spatial filtering. Forests were divided into 3 types such as conifers, broadleaved, and Korean pine (Pinus koriansis) forests. The applied radii of HRA were 4 km, 5 km and 10 km, respectively. The estimated biomass and mean bias for conifers forest was 222 t/ha and 1.8 t/ha when the value of k=8, the radius of HRA was 4 km, and $5{\times}5$ modal was filtered. The estimated forest biomass of Korean pine was 245 t/ha when the value of k=8, the radius of HRA was 4km. The estimated mean biomass and mean bias for broadleaved forests were 251 t/ha and -1.6 t/ha, respectively, when the value of k=6, the radius of HRA was 10 km. The estimated total forest biomass by k-NN method was 799,000t and 237 t/ha. The estimated mean biomass by ${\kappa}NN$method was about 1t/ha more than that of filed survey data.

• Journal of the Korean Home Economics Association
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• v.43 no.8 s.210
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• pp.141-159
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• 2005

The aim of this study was to investigate the current state of wife abuse in Seosan and the relationships between wife abuse and the related variables. A total of 132 couples took part in this study. All couples live in Seosan city, range in age from their 20s to 50s and each couple has at least one child. Stratification sampling method was used to select the couples. They were asked to complete self-report questionnaires. Subjects completed a Korean version of the self- esteem scale, marital conflict scale, communication style scale, family history of violence scale, alcohol dringking, and wife abuse scale. In order to examine the current state of wife abuse, such as, frequency, mean, standard deviation and paired t-test, t-test were calculated and analyzed. Next, to identify differences in wife abuse between the upper group and the lower group, t-test was peformed. Finally, to investigate the relative influences of independent variables upon wife-abuse, multiple regression analysis was peformed. All these analyses were conducted using SPSS 10.0 program. The results were as follows; 1) In terms of the current state of wife abuse, there are three main observations. First, $23\%$ of respondents answered that they had beat their spouse or been beaten by their spouse before and after their marriage. Second, compared with physical violence($2{\~}16\%$), other types of violence such as verbal($7{\~}4\%$), emotional($41{\~}64\%$), economical($3{\~}29\%$) and sexual violence($4{\~}38\%$) were reported to occur more often in these relationships. Third, following the abuse most wives tend to tolerate the situation instead of taking an active action like reporting the abuse to police. 2) As for the husbands, subjects that drank a high level of alcohol, blaming and super-reasonable communication style, and family history of violence reported more frequent cases of wife abuse. As for the wives, subjects with high levels of self-esteem, irrelevant communication style, marital conflict, and family history of violence reported having more cases of that abuse. 3) In the case of husbands, alcohol, communication style and family history of violence explained $40\%$ of wife abuse. In the case of wives, marital conflict and family history of violence explained $77\%$ of their experiences with abuse. This study makes the contribution to aims to develop education programs and family therapy relevant to prevent wife abuse and to reconsider the existing laws governing domestic violence in Korea.

• Journal of the Korean GEO-environmental Society
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• v.11 no.8
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• pp.83-93
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• 2010

The purpose of this study is to present emergency rehabilitation, cause and the countermeasure of reinforcement about reinforced retaining wall and the slope collapse of the phyllite ground. The study area is broken easily because this area has rock mass discontinuity such as stratification, foliation, joint and fold. And this area consists of the ground where it happens easily to the failure of structure like reinforced retaining wall because of the phyllite ground sensitive to weathering. Counterweight fill in front of reinforced retaining wall was performed as emergency rehabilitation about displacement of reinforced retaining wall and the failure at the rear of slope on phyllite ground. After that, additional displacement didn't occur. Boring and geophysical exploration were launched to present emergency rehabilitation and develop the long-term method of reinforcement. This could grasp anticipated range of the failure section and identify internal and external factors of the cause of the slope collapse. Several methods of reinforcement were suggested by conducting the numerical analysis. When conducting design and construction of major structures at the ground which has complex discontinuities, the precise site investigation should be conducted. During construction, immediate action for over-displacement should be taken by performing the periodic measurement.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.14
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• pp.5907-5912
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• 2015

Purpose: To evaluate and update evidence for prognostic effects of kidney-sparing (KS) management and nephroureterectomy (NU) for upper tract urothelial carcinomas. Materials and Methods: Pubmed, Embase and the Cochrane Library were retrieved for the identification of comparative studies of kidney-sparing procedure and nephroureterectomy for upper tract urothelial carcinoma prior to December 2014. The data were extracted independently by 2 reviewers and the quality of the included studies was assessed. Review Manager 5.3 and STATA 13 were used to perform the meta-analysis. Results: Twenty-three observational studies including 1,587 KS and 3,996 NU were evaluated. The results of the meta-analysis showed that nephroureterectomy had no significant benefit with regard to intravesical recurrence (IRFS), metastasis (MFS), cancer specific survival (CSS) and overall survival (OS) except the total tumor recurrence (RFS) when compared with kidney sparing management. The respectively pooled outcomes were HR 1.36 (0.69-2.68, P=0.38) for IRFS, 1.09 (0.59-2.01, P=0.78) for MFS, 1.17 (0.77-1.79, P=0.47) for CSS, 1.50 (0.90-2.48, P=0.12) for OS and 1.61 (1.03-2.51, P=0.04) for RFS. Conclusions: On the whole, kidney-sparing management had equivalent prognostic effect on upper tract urothelial carcinoma as the standard nephroureterectomy except in tumor recurrence. However, the results should be interpreted with caution for lack of stage and grade stratification and multi-center randomized controlled trials are still needed to verify our results.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.10
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• pp.5761-5767
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• 2013

The potential correlation of X-ray repair cross-complementing group 1 (XRCC1) Arg399Gln polymorphism with hepatocellular carcinoma (HCC) susceptibility is ambiguous. Taking account of inconsistent results of previous meta-analyses and new emerging literatures, we conducted a meta-analysis covering 15 case-control datasets to evaluate the relationship. Relevant studies from Medline, Embase and CNKI were retrieved. A fixed-effect model or a random-effect model, depending on between-study heterogeneity, were applied to estimate the association between XRCC1 polymorphism Arg399Gln and HCC risk with the results presented as odds ratios (ORs) and 95% confidence intervals (95% CIs). In accordance with Hardy-Weinberg equilibrium, 15 studies with data for 6,556 individuals were enrolled in this systematic review. For overall HCC,thr XRCC1 polymorphism Arg399Gln was significantly associated with HCC susceptibility in a homozygote model as well as in a dominant model (G/G vs. A/A, OR=1.253, p=0.028; G/G+A/G vs. A/A, OR= 1.281, p=0.047, respectively), but not in a heterozygote model (A/G vs. A/A, OR=1.271, p=0.066) or a recessive model (G/G vs. A/G + A/A, OR= 1.049, p=0.542). Similar results were also observed on stratification analysis by ethnicity (A/G vs. A/A, OR=1.357, p=0.025; G/G vs. A/A, OR=1.310, p=0.011; G/G+A/G vs. A/A, OR= 1.371, p=0.013). However, no potential contribution of XRCC1 Arg399Gln polymorphism to HCC susceptibility in HBV/HCV subgroups was identified. No publication bias was found in this study. In conclusion, the XRCC1 Arg399Gln polymorphism contributes to HCC susceptibility. Due to the lack of studies in Western countries, further large-sample and rigorous studies are needed to validate the findings.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.12
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• pp.5101-5106
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• 2016

Purpose: We aimed to establish an inflammatory prognostic index (IPI) in early and advanced non-small cell lung cancer (NSCLC) patients based on hematologic and biochemical parameters and to analyze its predictive value for NSCLC survival. Materials and Methods: A retrospective review of 685 patients with early and advanced NSCLC diagnosed between 2009 and 2014 was conducted with collection of clinical, and laboratory data. The IPI was calculated as C-reactive protein ${\times}$ NLR (neutrophil/ lymphocyte ratio)/serum albumin. Univariate and multivariate analyses were performed to assess the prognostic value of relevant factors. Results: The optimal cut-off value of IPI for overall survival (OS) stratification was determined to be 15. Totals of 334 (48.8%) and 351 (51.2%) patients were assigned to high and low IPI groups, respectively. Compared with low IPI, high IPI was associated with older age, greater tumor size, high lymph node involvement, distant metastases, advanced stage and poor performance status. Median OS was worse in the high IPI group (low vs high, 8.0 vs 34.0 months; HR, 3.5; p<0.001). Progression free survival values of the patients who had high vs low IPI were determined 6 months (95% CI:5.3-6.6) and 14 months (95% CI:12.1-15.8), respectively (HR; 2.4, P<0.001). On multivariate analysis, stage, performance status, lactate dehydrogenase and IPI were independent prognostic factors for OS. Subgroup analysis showed IPI was generally a significant prognostic factor in all clinical variables. Conclusion: The described IPI may be an inexpensive, easily accessible and independent prognostic index for NSCLC patients, useful for clinical practice.