• Asian Pacific Journal of Cancer Prevention
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• v.15 no.3
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• pp.1177-1180
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• 2014

Background: Anogenital warts (AGWs) are common results of sexually transmitted infection (STI). Human papillomavirus (HPV) types 6 and 11, which are non-oncogenic types, account for 90% of the clinical manifestations. Although the quadrivalent HPV vaccine has been launched, AGW remains prevalent in some countries and shows association with abnormal cervical cytology. Objectives: To study the prevalence of abnormal cervical cytology (low grade squamous intraepithelial lesions or worse; LSIL+) in immunocompetent Thai women newly presenting with external AGWs. Materials and Methods: Medical charts of all women attending Siriraj STI clinic during 2007-2011 were reviewed. Only women presenting with external AGWs who were not immunocompromised (pregnant, human immunodeficiency virus positive or being on immunosuppressant drugs) and had not been diagnosed with cervical cancer were included into the study. Multivariate analysis was used to determine the association between the characteristics of the patients and those of AGWs and LSIL+. Results: A total of 191 women were eligible, with a mean age of $27.0{\pm}8.9$ years; and a mean body mass index of $20.6{\pm}8.9kg/m^2$. Half of them finished university. The most common type of AGWs was exophytic (80.1%). The posterior fourchette appeared to be the most common affected site of the warts (31.9%), followed by labia minora (26.6%) and mons pubis (19.9%). The median number of lesions was 3 (range 1-20). Around 40% of them had recurrent warts within 6 months after completing the treatment. The prevalence of LSIL+ at the first visit was 16.3% (LSIL 12.6%, ASC-H 1.1%, HSIL 2.6%). After adjusting for age, parity and miscarriage, number of warts ${\geq}5$ was the only factor associated with LSIL+(aOR 2.65, 95%CI 1.11-6.29, p 0.027). Conclusions: LSIL+ is prevalent among immunocompetent Thai women presenting with external AGWs, especially those with multiple lesions.

• The Journal of the Acoustical Society of Korea
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• v.42 no.2
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• pp.133-142
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• 2023

The office environment is changing according to work types, Information Technology (IT) advancements, and the Coronavirus disease (COVID)-19 situation. In order for office space users to perform their tasks comfortably and efficiently, it is necessary to secure individual privacy as well as easy communication among members. In Korea, the demand for improving the acoustic performance of office spaces is also increasing, but the related performance criteria and guidelines have not been established. In this study, standardization of office space acoustic performance measurement and evaluation methods and European countries' acoustic performance criteria were compared and reviewed. It is proposed to comprehensively review international standardization trends and acoustic performance standards in each country and to establish and utilize criteria for evaluating the acoustic performance and satisfaction of office spaces in Korea through our survey. Considering the international standardization direction and compatibility with communication and Public Address (PA) systems, it is appropriate to establish criteria using the speech transmission index or Speech Transmission Index (STI) application index. This criterion will be highly utilizable and compatible. In addition, since the office furniture industry is interested in improving the acoustic performance of office space, it is necessary to establish a labelling system for speech level reduction of office furniture.

• Parasites, Hosts and Diseases
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• v.57 no.1
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• pp.1-8
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• 2019

There is no effective treatment modality available against different forms of leishmaniasis. Therefore, the aim of this study was to improve the penetration and efficacy of selenium and glucantime coupled with niosomes and compared them with their simple forms alone on in vitro susceptibility assays. In this study, the niosomal formulations of selenium and in combination with glucantime were prepared. The size and morphology of the niosomal formulations were characterized and the effectivity of the new formulation was also evaluated using in vitro MTT assay, intra-macrophage model, and gene expression profile. From the results obtained, no cytotoxicity effect was observed for niosomal and simple forms of drugs, as alone or in combination. Niosomal formulations of the drugs significantly showed more inhibitory effects ($P{\leq}0.001$) than the simple drugs when the selectivity index was considered. The gene expression levels of Interleukin (IL-10) significantly decreased, while the level of IL-12 and metacaspase significantly increased ($P{\leq}0.001$). The results of the present study showed that selenium plus glucantime niosome possess a potent anti-leishmanial effect and enhanced their lethal activity as evidenced by the in vitro experiments.

• Journal of Korea Technology Innovation Society
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• v.14 no.4
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• pp.833-859
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• 2011

This study aims to draw the characteristics of the regional operation system of the shared research instrument service, which contributes to the R&D investment efficiency by the avoidance of duplicated research instrument investment and the enhancement of the network collaboration. So from the perspective of technology infrastructure policy and regional innovation system, Gyeonggi region of Korean metropolitan area has been analyzed for the case study. The case study has been conducted by 2 step process of within-case analysis and cross-case analysis. Firstly, the characteristics of operation system of the shared research instrument have been examined through various research methods. Secondly, in the cross-case analysis, the examined issues and problems have been organized by the matrix of 3 organizational governance characteristics and 4 issues to facilitate the regional policy approach. The issues deducted by the cross-case analysis have been deducted as (1) 'usage fee charge system', 'relevant method for the performance index and measurement of the instrument service management' for the regional policy led case, (2) 'performance management issue', 'financial and managerial accounting system for the instrument operating division', and 'change of budget support scheme' for the joint operation case and lastly (3) 'usage facilitation after the expiration of research lab support project' for the university led case.

• Journal of Korea Water Resources Association
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• v.47 no.5
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• pp.483-490
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• 2014

The design procedures for a biological reactor and a secondary settling tank (SST) of an activated sludge system are based on the steady state design method (Ekama et al., 1986; WRC, 1984) and the 1-D flux theory design method (Ekama et al., 1997), respectively. This study combined both of the design procedures, to determine the optimum sludge concentration in the reactor and the best design with the lowest cost. The best design of the reactor volume and the SST diameter at the optimum sludge concentration were specified with varying wastewater and sludge characteristics, temperature, sludge retention time (SRT) and peak flow rate. The effects of the influent wastewater characteristics, such as substrate concentration and unbiodegradable particulate fraction, were found to be considerable, but the effect of unbiodegradable soluble fraction was to be negligible. The effects of sludge settling characteristics, were also significant. SRT, as an operating parameter, was found to be an important factor for determining the optimum sludge concentration. However, the effect of temperature was found to be small. Furthermore, for designing a large scale wastewater treatment plant, the number of reactors or SSTs could be estimated, by dividing the total reactor volume or SST area. The new combined design procedure, proposed in this research, will be able to allow engineers to provide the best design of an activated sludge system with the lowest cost.