• Journal of Acupuncture Research
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• 제17권1호
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• pp.119-127
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• 2000

To investigate the acupuncturing function of $ST_{36}$(足三里) on the gastric activity, four different treatment methods such as intact, local anesthesia, ligation and nerve dissection were implemented. Followings are the results from the present study. 1. When a simple acupuncture with intact, the stomach motility and frequency were increased without significance compared with control. 2. Under local anesthesia on femoral region, the stomach motility and frequency showed no such changes compared with control. 3. With ligation of femoral region, the stomach motility and frequency were decreased significantly compared with control. 4. When the siatic nerve was dissected, the stomach motility and frequency showed no such changes compared with control. Overall, the effect of acupuncture on the $ST_{36}$(足三里) was very closely related with the condition of surrounding area. It is assumed that further studies should be done for the investigation of mechanism behind the acupuncturing function in conjunction with the nervous system.

• Journal of Chest Surgery
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• 제21권2호
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• pp.283-290
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• 1988

St. Jude Medical cardiac valve replacement was performed in 90 consecutive patients from Jan. 1984 to Dec. 1987. 54 had mitral, 12 had aortic and 24 had multiple valve replacement. Follow up extended for 1 to 47 months[mean 17.1 month] with a cumulative period of 1351 months. The overall actuarial survival rate at 4 years was 87.1% and overall hospital mortality was 6.7%. The linearlized incidence of thrombotic obstruction, thromboembolism, valve failure was 0.8% / pt. yr. each. The lower incidence of valve related mortality or morbidity was statistically significant. The performance of the St. Jude Medical mechanical valve was excellent compared to other substitute valves and has low incidence of thromboembolism or valve failure.

• 대한영양사협회학술지
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• 제17권2호
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• pp.206-215
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• 2011

Currently, metabolic surgery (Laparoscopic Roux-en-Y gastric bypass, LRYGB) has an important role and should be recommended as an intervention in the management of obese patients with type 2 diabetes mellitus (T2DM). A successful outcome of surgery requires medical nutrition therapy. Therefore, we performed a retrospective study on 25 patients with T2DM who underwent LRYGB at Yeouido St. Mary's Hospital from October 2008 to May 2010. The patients were followed up for an average of 6 months after surgery (range: 2~19 months). Diabetes was resolved in 80% of the patients. Percentage of excess weight loss was (%EWL) was 56.2%. After surgery, fasting blood sugar (FBS) and HbA1c were significantly reduced (123 mg/dl, A1c 6.7%, P<0.001) and triglyceride was also significantly reduced to 107.6 mg/dl (P<0.05). As diets of the patients progressed from liquid to soft to regular diet, energy, carbohydrates, and fat intakes increased significantly (P<0.001). But protein intake did not change significantly. Nutrient intake of the patients after the surgery was significantly lower than the recommended diet for the non-surgery group. Patients experienced side-effects related to the diets after surgery, including hair-loss (76%), smelly gas (52%), vomiting (48%), etc. A significantly positive correlation was observed between vomiting and FBS (P<0.001). There was a significant relationship between side effects and the amount of nutrient intakes. Therefore, guide patients to a diet progression with treatment to minimize side effects, especially vomiting. And monitor their dietary life to be healthy and not to regain weight until remission of T2DM.

• Clinical and Experimental Emergency Medicine
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• 제5권4호
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• pp.249-255
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• 2018

Objective As aging progresses, clinical characteristics of elderly patients in the emergency department (ED) vary by age. We aimed to study differences among elderly patients in the ED by age group. Methods For 2 years, patients aged 65 and older were enrolled in the study and classified into three groups: youngest-old, ages 65 to 74 years; middle-old, 75 to 84 years; and oldest-old, ${\geq}85years$. Participants' sex, reason for ED visit, transfer from another hospital, results of treatment, type of admission, admission department and length of stay were recorded. Results During the study period, a total 64,287 patients visited the ED; 11,236 (17.5%) were aged 65 and older, of whom 14.4% were 85 and older. With increased age, the female ratio (51.5% vs. 54.9% vs. 69.1%, P<0.001), medical causes (79.5% vs. 81.3% vs. 81.7%, P=0.045), and admission rate (35.3% vs. 42.8% vs. 48.5%, P<0.001) increased. Admissions to internal medicine (57.5% vs. 59.3% vs. 64.7%, P<0.001) and orthopedic surgery (8.5% vs. 11.6% vs. 13.8%, P<0.001) also increased. The ratio of admission to intensive care unit showed no statistical significance (P=0.545). Patients over age 85 years had longer stays in the ED (330.9 vs. 378.9 vs. 407.2 minutes, P<0.001), were discharged home less (84.4% vs. 78.9% vs. 71.5%, P<0.001), and died more frequently (6.3% vs. 10.4% vs. 13.0%, P<0.001). Conclusion With increased age, the proportion of female patients and medical causes increased. Rates of admission and death increased with age and older patients had longer ED and hospital stays.

• Journal of Chest Surgery
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• 제56권2호
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• pp.99-107
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• 2023

Background: The neutrophil-to-lymphocyte ratio (NLR) has been suggested as a novel predictive marker of cardiovascular disease. However, its prognostic role in patients under-going coronary artery bypass grafting (CABG) is unclear. This study aimed to determine the association between the preoperative NLR and early mortality in patients undergoing CABG. Methods: Cardiac surgery was performed in 2,504 patients at Seoul St. Mary's Hospital from January 2010 to December 2021. This study retrospectively reviewed 920 patients who underwent isolated CABG, excluding those for whom the preoperative NLR was unavailable. The primary endpoints were the 30- and 90-day mortality after isolated CABG. Risk factor analysis was performed using logistic regression analysis. Based on the optimal cut-off value of preoperative NLR on the receiver operating characteristic curve, high and low NLR groups were compared. Results: The 30- and 90-day mortality rates were 3.8% (n=35) and 7.0% (n=64), respectively. In the multivariable analysis, preoperative NLR was significantly associated with 30-day mortality (odds ratio [OR], 1.28; 95% confidence interval [CI], 1.17-1.39; p<0.001) and 90-day mortality (OR, 1.17; 95% CI, 1.07-1.28; p<0.001). The optimal cut-off value of the preoperative NLR was 3.4. Compared to the low NLR group (<3.4), the high NLR group (≥3.4) showed higher 30- and 90-day mortality rates (1.4% vs. 12.1%, p<0.001; 2.8% vs. 21.3%, p<0.001, respectively). Conclusion: Preoperative NLR was strongly associated with early mortality after isolated CABG, especially in patients with a high preoperative NLR (≥3.4). Further studies with larger cohorts are necessary to validate these results.

• 대한족부족관절학회지
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• 제17권4호
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• pp.272-276
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• 2013

Purpose: Recurrence is one of the most common complications after primary correction for hallux valgus deformities. The purpose of this study was to evaluate the usefulness of Scarf osteotomy with axial decompression in the treatment of recurrent hallux valgus. Materials and Methods: From April 2006 to April 2011, 14 cases (12 patients) of recurrent hallux valgus were managed with shortening Scarf osteotomy. Preoperative and postoperative radiographs were reviewed for the measurement of the hallux valgus angle (HVA), intermetatarsal angle (IMA), and the amount of the $1^{st}$ metatarsal shortening. Clinical outcomes including the visual analogue scale (VAS), the AOFAS score, and the range of motion [ROM] of the 1st metatarsophalangeal (MTP) joint were evaluated. Results: The mean HVA decreased from 27.9 degrees to 5.2 and the mean IMA decreased from 12.9 to 3.4. The mean VAS improved from 5.3 to 0.3 and the mean AOFAS score improved from 41 to 90. The mean amount of the 1st metatarsal shortening was 3.4 mm (2-5). The mean ROM of the $1^{st}$ MTP joint improved from 22 degrees (15-35) to 68 (55-75). Conclusion: Scarf osteotomy associated with axial decompression can be a useful revision procedure for the treatment of recurrent hallux valgus deformity.

• 한국패류학회지
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• 제18권1호
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• pp.41-52
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• 2002

2000년 6월부터 5월까지 제주남부연안 송악산주변 지역 조간대 3개 지역 9개 지점에 대한 조간대 저서무척추동물의 공간적인 수직분포와 군집유형에 관하여 연구하였으며 그 결과를 요약하면 다음과 같다. 조사기간 중 조사구역 3개 지역 조간대에서 서식하는 저저무척추동물은 총 6문, 12강, 25목, 50과, 104종이었다. 분류군별 출현종을 보면 연체동물이 3강, 69종(66.3%), 절지동물 3강, 17종 (16.3%) 이었다. 조간대의 구역별 종다양성에서는 하부조간대구역으로 내려갈수록 높았으며, 조사지점별 다양성에서는 뚜렷한 차이가 없었다. 조간대 구역별 우점종의 수직분포는 상부조간대의 좁쌀무늬총알고둥 (N. exigua), 총알고둥 (L. brevicula), 거북손 (P. mitella mitella), 갈고 둥 (N. japonica), 중부조간대는 각시고둥 (M. neritoides), 눈알고둥 (L. coronata corensis), 갈고둥 (N. japonica) 그리고 하부 조간대구역은 배무래기 (N. schrenckii), 애기밤고둥 (O. nigerrimusa), 대수리 (P. clavigera), 밤고둥 (C. argyrostoma lischkei)의 순이었다. 9개 지점간 유사도는 높았으며 2개 그룹으로 나눌 수 있었는데 St. 1, St, 2, St. 4, St. 8, St. 9가 한 그룹, St. 3, St. 5, St. 6, St. 7이 같은 그룹이었으나 두 그룹간 차이는 크지 않았다.

• 대한한의학회지
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• 제16권2호
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• pp.9-16
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• 1995

1994년 3월부터 1995년 2월까지 1년동안 말초성 안면신경마비로 경희의료원 한방병원 침구1과에 침치료를 받기 위하여 내원한 환자중 발병한지 1주일 이내로 이부(耳部) 대장포진(帶狀疱疹)이나 종양 또는 외상을 당하지 않은 초발환자 44명을 대상으로 일주일에 3회씩 합곡(合谷)(L14), 족삼리(足三里)(ST36), 영향(迎香)(LI20), 찬죽(BL2), 예풍(TE17), 지창(地倉)(ST4), 협차(頰車)(ST6), 수구(水溝)(GV26), 승장(承漿)(CV24), 양백(陽白)(GB14)과 어요(魚腰)(Ex-HN4)를 선혈(選穴)하여 자침하고 치료경과를 관찰하였다. 지창(地倉)에서 협차(頰車), 수구(水溝)와 승장(承漿)에서 지창(地倉), 양백(陽白)에서 어요(魚腰)로는 투자법을 실시하였다. 환자의 평균연령은 39.3세이었고, 여성이 63.6%를 차지하였고 그중 한 명은 임신중이었다. 안면신경마비의 회복판정 척도는 House-Brackmann facial nerve grading scales를 사용하여 초진부터 초진후 7주까지 또는 7주이내 완전히 회복될 때까지 매주 평가하였다. 86.4%의 환자가 초진후 7주이내에 완전히 회복 되었으며, 회복되는데 걸리는 기간은 평균 3.7주로 관찰되었다.

• Korean Journal of Radiology
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• 제23권2호
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• pp.256-263
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• 2022

Objective: This study aimed to evaluate the image quality and dose reduction of low-dose three-dimensional (3D) rotational angiography (RA) for evaluating intracranial aneurysms. Materials and Methods: We retrospectively evaluated the clinical data and 3D RA datasets obtained from 146 prospectively registered patients (male:female, 46:100; median age, 58 years; range, 19-81 years). The subjective image quality of 79 examinations obtained from a conventional method and 67 examinations obtained from a low-dose (5-seconds and 0.10-μGy/frame) method was assessed by two neurointerventionists using a 3-point scale for four evaluation criteria. The total image quality score was then obtained as the average of the four scores. The image quality scores were compared between the two methods using a noninferiority statistical testing, with a margin of -0.2 (i.e., score of low-dose group - score of conventional group). For the evaluation of dose reduction, dose-area product (DAP) and air kerma (AK) were analyzed and compared between the two groups. Results: The mean total image quality score ± standard deviation of the 3D RA was 2.97 ± 0.17 by reader 1 and 2.95 ± 0.20 by reader 2 for conventional group and 2.92 ± 0.30 and 2.95 ± 0.22, respectively, for low-dose group. The image quality of the 3D RA in the low-dose group was not inferior to that of the conventional group according to the total image quality score as well as individual scores for the four criteria in both readers. The mean DAP and AK per rotation were 5.87 Gy-cm² and 0.56 Gy, respectively, in the conventional group, and 1.32 Gy-cm² (p < 0.001) and 0.17 Gy (p < 0.001), respectively, in the low-dose group. Conclusion: Low-dose 3D RA was not inferior in image quality and reduced the radiation dose by 70%-77% compared to the conventional 3D RA in evaluating intracranial aneurysms.

• Journal of Microbiology and Biotechnology
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• 제27권11호
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• pp.1983-1993
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• 2017

Salmonella enterica subsp. enterica serovar Typhimurium, one of the most common foodborne pathogens, is transmitted mainly through contaminated food derived from infected animals. In this study, S. Typhimurium ST1120, an isolate from pig feces in Korea, was subjected to whole-genome analysis to understand its genomic features associated with virulence. The genome of ST1120 was found to have a circular chromosome of 4,855,001 bp (GC content 52.2%) and a plasmid of 6,863 bp (GC content 46.0%). This chromosome was predicted to have 4,558 open reading frames (ORFs), 17 pseudogenes, 22 rRNA genes, and 86 tRNA genes. Its plasmid was predicted to have three ORFs. Comparative genome analysis revealed that ST1120 was phylogenetically close to S. Typhimurium U288, a critical isolate in piggery farms and food chains in Europe. In silico functional analysis predicted that the ST1120 genome harbored multiple genes associated with virulence and stress resistance, including Salmonella pathogenicity islands (SPIs containing SPI-1 to SPI-5, SPI-13, and SPI-14), C63PI locus, ST104 prophage locus, and various antibiotic resistance genes. In accordance with these analysis results, ST1120 showed competence in invasion and survival abilities when it was added to host cells. It also exhibited robust resistance against antibiotics in comparison with other S. Typhimurium strains. This is the first report of the complete genome sequence of S. Typhimurium isolated from swine in Korea. Comparative genome analysis between ST1120 and other Salmonella strains would provide fruitful information toward understanding Salmonella host specificity and developing control measures against S. Typhimurium infection.