• 대한족부족관절학회지
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• 제7권1호
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• pp.101-108
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• 2003

Purpose: To evaluate and analyze the incidence, clinical features, cause and surgical outcomes of iatrogenic hallux varus deformity after hallux valgus surgery. Materials and Methods: Twenty-six Hallux varus deformities after hallux valgus surgery were evaluated. Clinical tolerability, patient's satisfaction and the main causative factor for varus deformity were evaluated. Radiologically, we measured the 1st intermetatarsal angle and hallux valgus angle on pre- & postoperatively. Results: 10 cases of 26 varus deformities were clinically intolerable. The patients complaint of mainly cosmetic and shoe fitting problems rather than pain and the main cause of deformities were over-correction of 1 st intermetatarsal angle. Radiologically, the average 1st intermetatarsal angle was 2.4 degrees and the hallux valgus angle was -9.2 degrees. After varus correction surgery, the average follow up were 17 months and the average 1st intermetatarsal angle was 2.3 degrees and the hallux valgus angle was 2.7 degrees. The average score of AOFAS Hallux Metatarsophalangeal -Interphalangeal Scale was 91 points. Conclusion: The hallux varus deformity after hallux valgus surgery came from mainly overcorrection of 1 st intermetatarsal angle. The management composed of just observation, tendon transfer and fusion, and each method could get satifactory results with appropriate indication.

• 한국의료질향상학회지
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• 제15권2호
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• pp.59-64
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• 2009

문제: 2008년 수입예산의 편성을 위해 2개년도의 수입 구조를 비교 했을 때 검사공간의 부족외에 여러 내부적요인과 동일 권역에 경쟁 건진센터의 건립 등 외부적요인이 복합적으로 작용하여 수입의 감소가 예견되고 있는 상황이었다. 목적: 해결 가능한 내부적 요인을 찾아 시정하고 외부적 요인에 대해서도 적극적으로 대처하여 수입을 증가 시킬 방안을 실행한다. 의료기관: 서울에 소재한 대학병원의 건강증진센터 질 향상 활동: 수입을 감소 시키는 원인을 내부와 외부로 나누어 분석하고 개선 할 수 있는 방안을 찾아내고 실현가능 한 것을 시행하였다. 개선효과: 개선 활동 후 건강검진 수입이 전년대비 27%, 수입이 가장 높았던 해와 비교 할 때 17%가 증가 한 것으로 나타났다. 교훈: 수입감소를 유발 하는 요인들을 여러경로를 통해 문제점을 수집 및 분석하고 고객이 요구하는 것을 파악하는 것이 최우선이었다. 그 결과 장비 신규 구입과 건진센터 규모의 확대와 같은 시설과 장비의 개선, 해외의료홍보, 텔레마케터의 양성과 교육 등과 같이 여러부서에 걸쳐 협조가 필요한 사항과, 새로운 건진프로그램의 개발 및 영업력의 강화 등 부서 차원의 프로세스 개선과 교육을 통해 고객에게 한걸음 더 다가 가는 것이 가장 중요 한 요소로 나타났다.

• 지역사회간호학회지
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• 제16권4호
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• pp.404-414
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• 2005

Objectives: The present study proposed to evaluate 1st-month and 3rd-month health status, depression, self-efficacy and medical expenses of a community-based health promotive self-management program for old Koreans. Method: Participants in the CDSMP were selected from elders in a community health center through convenient sampling. The program included a 3-hour session per week for 14 weeks. Outcomes of evaluation in the 1st month and the 3rd month included modified Self-rated Health Status Scale, Center for Epidemiologic Studies Short Depression Scale, Self-Efficacy for Managing Chronic Disease 6-item Scale, and 1-item Medical Expenses Scale. Results: Self-rate health scores increased significantly just after the intervention (16.22), in the 1st month (17.57) and in the 3rd month (19.04) (x2=32.06. p=.000); Depression scores (reversed) also increased significantly just after the intervention (6.04), in the 1st month (7.75) and in the 3rd month (8.39) ( $x^2=29.92$. p=.000); Self-efficacy score increased significantly just after intervention (12.87) but it decreased in the 1st month (12.73) and in the 3rd month (12.04). But all of the three scores were still higher than those before the intervention (8.65) ($x^2=32.42$. p=.000): Medical expense score decreased at the end of the intervention (1.57) but the cost score increased in the 1st month (2.48) and in the 3rd month (2.39) ($x^2$=7.81. p=.050). Conclusion: CDSMP is effective in increasing self-rate health and self-efficacy and in decreasing depression in the Korean elderly. However, no significant effect of the program was observed in decreasing the medical cost of the Korean elderly.

• 방사선산업학회지
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• 제6권2호
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• pp.129-138
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• 2012

Proteomic analysis was performed in order to identify proteomic changes by salt stress between the Japonica cv. Donganbyeo (WT) and two salt-tolerant (ST) mutant lines by using the SDS-PAGE and 2-DE. Two salt tolerant rice mutant lines, ST-87 and ST-301, were selected by in vitro mutagenesis with gamma-ray. Three-week-old seedlings were treated with 171 mM NaCl for 7 days. In the SDS-PAGE, three proteins with molecular weights of 27, 46 and 58 kDa were highly increased under salt treatment. Total proteins from shoots of both WT and ST-lines were separated by two-dimensional gel electrophoresis. In 2-DE, 201, 226, 217 and 213 protein spots were detected in the untreated-or treated-WT and untreated- or treated-ST-87, respectively. Of theses, 17 and 10 protein spots were up- and down-regulated under salt stress in the WT, respectively. While, 16 and 8 protein spots were up- and down-regulated under salt stress in the ST-87, respectively, compared with the untreated plants. High intensity or de novo synthesized proteins were analyzed by MALDI-TOF/MS analysis.

• Journal of Chest Surgery
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• 제52권3호
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• pp.131-140
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• 2019

Background: The purposes of this study were to evaluate the appropriateness of the stage migration of stage IIA non-small cell lung cancer (NSCLC) in the seventh edition of the tumor, node, and metastasis classification for lung cancer to stage IIB lung cancer in the eighth edition, and to identify prognostic factors in patients with eighth-edition stage IIB disease. Methods: Patients with eighth-edition stage IIB disease were subclassified into those with seventh-edition stage IIA disease and those with seventh-edition stage IIB disease, and their recurrence-free survival and disease-specific survival rates were compared. Risk factors for recurrence after curative resection were identified in all included patients. Results: Of 122 patients with eighth-edition stage IIB NSCLC, 101 (82.8%) had seventh-edition stage IIA disease and 21 (17.2%) had seventh-edition stage IIB disease. Nonsignificant differences were observed in the 5-year recurrence-free survival rate and the 5-year disease-specific survival rate between the patients with seventh-edition stage IIA disease and those with seventh-edition stage IIB disease. Visceral pleural invasion was a significant risk factor for recurrence in patients with eighth-edition stage IIB NSCLC. Conclusion: The stage migration from seventh-edition stage IIA NSCLC to eighth-edition stage IIB NSCLC was appropriate in terms of oncological outcomes. Visceral pleural invasion was the only prognostic factor in patients with eighth-edition stage IIB NSCLC.

• Clinical Endoscopy
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• 제57권1호
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• pp.36-47
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• 2024

Background/Aims: Scissor-type endoscopic submucosal dissection (ST-ESD) knives can reduce the adverse events associated with ESDs. This study aimed to compare ST-ESD and non-scissor-type (NST)-ESD knives. Methods: We identified ten studies that compared the performance characteristics and safety profiles of ST-ESD and NST-ESD knives. Fixed- and random-effects models were used to calculate the pooled proportions. Heterogeneity was assessed using the I² test. Results: On comparing ST-ESD knives to NST-ESD knives, the weighted odds of en bloc resection was 1.61 (95% confidence interval [CI], 0.90-2.90; p=0.14), R0 resection was 1.10 (95% CI, 0.71-1.71; p=0.73), delayed bleeding was 0.40 (95% CI, 0.17-0.90; p=0.03), perforation was 0.35 (95% CI, 0.18-0.70; p<0.01) and ESD self-completion by non-experts was 1.89 (95% CI, 1.20-2.95; p<0.01). There was no heterogeneity, with an I² score of 0% (95% CI, 0%-54.40%). Conclusions: The findings of reduced odds of perforation, a trend toward reduced delayed bleeding, and an improvement in the rates of en bloc and R0 resection with ST-ESD knives compared to NST-ESD knives support the use of ST-ESD knives when non-experts perform ESDs or as an adjunct tool for challenging ESD procedures.

• 한국잠사곤충학회지
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• 제16권1호
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• pp.77-84
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• 1974

개량 Mulching 담배조기재배에 따른 Nicotine이 뽕잎에 오독되었을 경우 누에에 영향을 주는 잔류독성 기간을 알고져 담배 품종 Hicks인 25a의 개량 Mulching재배 담배밭에 1973년 6월 18일∼8월 4일 까지 47 일간 동년 춘식한뽕 pot를 격휴로 배치하여 Nicotine 오독 처리구를 설정하고 무처리인 대조구는 동일한 일조 몇 통퐁조건을 위하여 춘벌뽕밭 이랑에 동일하게 설치하고 pot격리일로 부터 5(1차), 15(2차), 25(3차), 50(4차) 일 별로 시기를 연장급여시킨 시험에서 1,2,3차는 3령까지 경과시수와 각령별 기잠체중, 지면잠비율 및 생존율을 조사했고, 4차는 4령까지 동일한 방범으로 조사한 결과, 1. 1∼2령 경과시수는 대조구에 비하여 처리구는 1 차가 28시간으로 12％, 2차는 37시간으로 17％, 3차는 50시간으로 23％, 4차는 43시간으로 17％의 경과가 길어졌으며 4차에 있어서 3∼4령 경과는 55시간으로 18％의 경과가 길었다. 2. 각령별 기잠체중에 있어서 2령은 3,4차, 3령은 1∼4차, 4령은 pot격리 50 일후에 소잠한 4차에 있어서도 각 시기 공히 대조구에 비해 처리구의 기잠체중이 감소되었다. 3. 각령별 지면잠비율에 있어서는 2령은 3,4차, 3령은 5차를 제외한 1,2,4차, 4령은 4차까지도 대조구에 비해 처리구는 지면잠비율이 높았다. 4. 각령별 생존율에 있어서는 2령은 2∼4차, 3령은 1∼4차, 4령은 4차까지도 대조구에 비해 처리구는 생존율이 낮았다. 이상을 종합하여보면 Nicotine함량이 적은 Hicks품종의 담배밭에서 오독 시킨 뽕잎이 pot격리일로 부터 50일 후의 처리에도 그 독성이 인정되었으며 4차소잠(pot격리 50일)구의 누에 경과시수를 감안할 때 60여일 까지도 독성이 잔류될 것으로 추정할 수 있었고 담배 품종 및 오독조건의 정도에 따라서는 그 이상 길어질 가능성도 보였다.

• 기술사
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• 제34권5호
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• pp.10-17
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• 2001

The 17th World Cup Event that raises a storm of excitement ever held in the New Millenium will be started with the opening game In Seoul, Korea, on 31st May,'02 and closed with the final match in Yokohama, Japan on 30th June'02 The 2002, FIFA World Cup held In Asian region for the first time in FIFA history is jointly-organized by Korea and Japan. Both Korea and Japan will host each 32 games at the chosen ten local venues in each countries Partierpants from 32 regional countries included host countries Korea and Japan as well as the previous Champion France are scheduled to match one another by tournament method

• Radiation Oncology Journal
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• 제12권2호
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• pp.191-199
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• 1994

Purpose : This study was undertaken to show the clinical results of combined radiotherapy and hyperthermia in primary hepatoma Materials and Methods : Between December 1989 and March 1993, 50 patients with hepatomas were treated by combined radiotherapy and hyperthermia. Among them, we analyzed retrospectively 33 patients who received the complete course of treatment. The ages of the patients ranged from 36 to 75(mean age: 55.5 years). Twenty-six patients ($78.8\%$) were men, and 7 ($21.2\%$ were women. According to Child's classification, nine patients ($27.3{\%}$) were A group, 9 ($27.3\%$) were B group, 15 ($45.4\%$) were C group. Radiation therapy was done by a 6 MV and 15 MV linear accelerator. Patients were treated with daily fractions of 150-180 cCy to doses of 2550 cGy -4950 cGy (median : 3000 cGy). Local hyperthermia was done by 8 MHZ RF capacitive heating device (Cancermia. Green Cross Co., Korea), 50-60 min/session, 1-2 sessions/wk, and 8.5 sessions (median number)/patient. We analyzed the prognostic factors including age, sex, tumor type, Child's classification, $\alpha$-fetoprotein, liver cirrhosis, ascites, portal vein invasion, esophageal varix, number of hyperthermia, chemotherapy, total bilirubin level, Karnofsky perfomance status. Results : The overall 1-year survival was $24.2\%$, with a mean survival of 10months. Of 33 patients, tumor regression (PR+MR) was seen in $30.4\%$, no response was seen in $52.2\%,\;17.4\%$ patient was progressed. In patients who had tumor regression, the overall 1-year survival was $42.1\%$ with a mean survival of 14 months. Factors influencing the survival were sex (p=0.05), tumor type (p=0.0248), Child's classification (p=0.0001), liver cirrhosis (p=0.0108), ascites (p=0.0009), and Karnofsky perfomance status (p=0.0028). Complications developed in 28 patients, including 18 hot pain,5 fat necrosis, 3 transient fever, 2 nausea and vomiting. Conclusion : In this study, the results suggests that combined radiotherauy and hyperthermia may improve the survival rate of hepatoma.

• 한국가축번식학회지
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• 제17권2호
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• pp.85-92
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• 1993

In the previous study, we observed that Purine has a time dependent effect in maintaining the oocytes in meiotic arrest, and human fetal cord serum(HFCS) and human mature follicular fluid(HMFF) reverse the GVBD suppressed by purines. And it was reported that purine has a harmful effect on the development of oocytes or embryos, when they were cultured for a long time, in vitro. Therefore this study was performed to investigate the effects of purine on extrusion rates of 1st pb and viability of oocytes cultured for a long time, in vitro. Immature oocytes(GV stage) were collected from ovaries of 25~28 day old ICR mice at 48 hrs after PMSG injection. Cumulus-enclosed and denuded oocytes collected were assigned randomly to one of several culture conditions. Some of the oocytes were cultured in 4mM hypoxanthine for 24hr, and the extrusion rates of 1st pb and viability of the oocytes were assessed at every 12 hrs. In the viability, the oocytes showed granulation, pigmentation of cytoplasm or lysis of 1st pb extruded were regarded as degenerating oocytes. Also some of the oocytes were cultured in hypoxanthine for 12 hrs then the resulting oocytes were transferred to hypoxanthine-free medium and cultured for 12 hrs to determine whether the inhibitory effect of hypoxanthine on the 1st pb extrusion was reversible. The rest of the oocytes were cultured in medium containing hypoxanthine and adenosine for 18 hrs to compare the 1st pb extrusion be attendant upon hte concentration of HFCS or HMFF supplemented. Hypoxanthine suppressed the extrusion of 1st pb and viability of the oocytes significantly, when they were cultured for more than 12 hrs and the harmful effect of hypoxanthine was showed in denuded oocytes, prominently. The suppressive effect of hypoxanthine was reversed by just removal of the hypoxanthine from the cultrue medium. Also there was no difference in reverse the pb extrusion rate suppressed between HFCS and HMFF. The extrusion rate of 1st pb in medium containing adenosine and hypoxanthine was increased in line with the concentration of HFCS or HMFF supplemented. Hypoxanthine suppressed the extrusion of 1st pb and viability of the oocytes significantly, when they were cultured for more than 12 hrs and the harmful effect of hypoxanthine was showed in denuded oocytes, prominetly. The suppressive effect of hypoxanthine was reversed by just removal of the hypoxanthine fromthe culture medium. Also there was no difference in reverse the pb extrusion rate suppressed between HFCS and HMFF. The extrusion rate of 1st pb in medium containing adenosine and hypoxanthine was increased in line with the concentration of HFCS or HMFF supplemented.