• Title/Summary/Keyword: SPRE

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An Algorithm of Solution for the Exceptional Field Problem in the Speculative Partial Redundancy Elimination(SPRE) Optimization (추론적 부분 중복 제거의 최적화 예외 영역 문제 해결 알고리즘)

  • Shin, Hyun-Deok;Ahn, Heui-Hak
    • The KIPS Transactions:PartA
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    • v.13A no.6 s.103
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    • pp.489-494
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    • 2006
  • This paper improves the algorithms for Speculative Partial Redundancy Elimination(SPRE) proposed by Knoop et al. This research brings up an issue concerning a field to which SPRE cannot be applied, and suggests a solution to the problem. The Improved SPRE algorithm performs the execution speed optimization based on the information on the execution frequency from profiling and the memory space optimization.

A Study on the Anti-inflammatory and Anti-allergic Effect of Salvia plebeia R. extracts (배암차즈기(Salvia plebeia R.) 추출물의 항염 및 항 알레르기 효과)

  • Jo, Sun-Young;Lee, Ui-Young;Kim, Eun-Young;Lee, Sue-Jung;Her, Jin-Woo;Yoon, Taek-Joon
    • Korean Journal of Pharmacognosy
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    • v.41 no.1
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    • pp.31-37
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    • 2010
  • The Salvia plebeia R. which is the biennial plant belonging to the Labiatae department, grows naturally in the Korea entire area. Presently, its extract (SPRE) is known to have an anti-inflammation and anti-allergy activity, but there are a few evidences about it. SPRE inhibits pro-inflammatory cytokine such as TNF-$\alpha$ and IL-6 as well as nitric oxide (NO) production in lipopolysaccharide (LPS) treated- macrophages. The co-administration of SPRE during OVA sensitization significantly reduced total IgE levels in mice. The mice who received SPRE co-administered with OVA showed a significant increase in serum OVA-specific IgG2a/b levels. Spleen-cell cultures harvested from OVA-sensitized mice showed a significant decrease in Th2 cytokine levels with a concomitant increase in Th1 cytokine levels only when SPRE co-administered with OVA. These results demonstrate that SPRE can control the LPS-induced inflammatory reaction and prevent antigen-induced Th2 immune responses in mice.

Program Osptimality Using Network Partiton in Embedded System (임베디드 시스템에서 네트워크 분할을 이용한 프로그램 최적화)

  • Choi Kang-Hee;Shin Hyun-Duck
    • Journal of the Korea Computer Industry Society
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    • v.7 no.3
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    • pp.145-154
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    • 2006
  • This paper improves algorithms of Speculative Partial Redundancy Elimination(SPRE) proposed by Knoop et al. Improving SPRE algorithm performs the execution speed optimization based on the information of the execution frequency from profiling and the memory space optimization. The first purpose of presented algorithm is to reduce in space requirements and the second purpose is to de crease the execution time. Since too much weight on execution speed optimization may cause the explosion of the memory space, it is important to consider the size of memory. This fact can be a big advantage in the embedded system which concerns the required memory size more than the execution speed In this paper we implemented the min-cut algorithm, and this algorithm used the control flow graph is constructed with network and partitioned.

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Surface Plasmon Resonance Ellipsometry Using an Air Injection System with an Extraction of Air System (공기주입 장치와 공기제거 장치를 사용한 표면 플라즈몬 공명 타원계측기)

  • Lee, Hong-Won;Cho, Eun-Kyoung;Jo, Jae-Heung;Won, Jong-Myoung;Shin, Gi-Ryang;CheGal, Won;Cho, Yong-Jai;Cho, Hyun-Mo
    • Korean Journal of Optics and Photonics
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    • v.20 no.3
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    • pp.182-188
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    • 2009
  • The surface plasmon resonance ellipsometer (SPRE), using a multiple air injection system with an extraction of air system, has been proposed and developed to minimize measurement error of signals due to diffusion of reagent into running buffer. Since the diffusion of reagent into running buffer affects the refractive index of the running buffer by changing the concentration, characteristics of binding between various bio-molecules don't appear clearly in measurement results. The diffusion between running buffer and reagent can be blocked by using an air bubble injection system. An extraction of air system is used to remove the noise signal due to unnecessary air bubbles flowing in a channel. Reliability of measurement results has been improved by using the valve system.

Anti-oxidative and Anti-allergic Effects of Salvia plebeia R. Ethanol Extracts (배암차즈기(Salvia plebeia R.) 에탄올 추출물의 항산화 및 항알레르기 효과)

  • Choi, Bong-Kyoum;Lee, Seon-Hye;Kim, Nam-Seok;Cho, Soo-Yeon;Jang, Hwan-Hee;Kim, Jung-Bong;Lee, Young Min;Yoon, Sungeun;Lee, Sung-Hyen
    • Korean Journal of Pharmacognosy
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    • v.45 no.4
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    • pp.332-337
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    • 2014
  • The Salvia plebeia R. which is the biennial plant belonging to the labiatae department, grows widely in Korea. This study was performed to evaluate the antioxidant activities and anti-allergic effects of Salvia plebeia R. leaves (SPLE) or roots (SPRE). Using ethanol extracts, both leaves and roots induced significant radical scavenging activity against DPPH and ABTS radicals in a dose dependent manner (p<0.05). Superoxide dismutase (SOD)-like activity of SPLE was significantly higher than that of SPRE at all concentrations. Treatment of the RBL-2H3 cells with SPLE and SPRE in vitro decreased ${\beta}$-Hexosaminidase release and significantly inhibited IgE-antigen complex-mediated IL-4 and TNF-${\alpha}$ mRNA expression in RBL-2H3 cells. These findings suggest that Salvia plebeia R. can protect or reduce allergic asthma through high antioxidant and anti-allergic reactions.

Comparison of Virulence Factors of Enterococci from Intestinal Drugs, Infant Feces and Clinical Isolates (정장제, 신생아 분변 및 병원에서 분리한 장구균의 병독성인자 비교)

  • Lee, Jeong-Hyun;Hwang, Sung-Woo;Kang, Kyung-Ran;Kim, Dong Hee;Kim, Chun-Gyu
    • KSBB Journal
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    • v.28 no.1
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    • pp.54-59
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    • 2013
  • Three isolates, E. faecium P1, P2 and P3, from intestinal drugs of three phamaceutical companies, four clinical vancomycin resistant isolates, E. faecium V1, V2, V3 and E. faecalis V4, and three isolates, E. faecalis DW01, DW07 and DW14, from infant feces were tested for the presence of virulence genes, ace, agg, esp, efaA, gelE, sprE, vanA and vanB as well as fsrABC, regulatory genes of gelE and sprE, cylMBA, cytolysin activation genes and cpd, cob and ccf, pheromone genes by PCR and for their phenotype activities such as protease, biofilm formation, cell clumping and hemolysis. The genes encoding cell surface adherence proteins, ace, agg, esp and efaA, were predominantly amplified from the vancomycin resistant strain V4 and the fecal isolates DW01, DW07 and DW14. Both protease and biofilm formation activity were detected only from E. faecalis V4 from which the PCR products of gelE and spreE as well as fsrABC were amplified. The pheromone genes were amplified from the V4, DW01, DW07 and DW14 strains and these strains showed clumping activity. Biofilm formation was observed from the strains DW01, DW07 and DW14, all of which produced PCR products of pheromone, and V4 as well. Whole cytolysin regulator genes were amplified from DW01, DW07 and DW14 and ${\beta}$-hemolysis activity was detected from these strains. Any virulence genes or activities except the pheomone gene ccf were not detected from the pharmaceutical isolates, E. faecium P1, P2 and P3.