• Laboraroty Animal Research
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• 제34권4호
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• pp.270-278
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• 2018

This study was conducted to compare the anesthetic effects of 2,2,2-tribromoethanol (TBE, $Avertin^{(R)}$) in ICR mice obtained from three different sources. TBE (2.5%) was intraperitoneally injected at three doses: high-dose group (500 mg/kg), intermediate-dose group (250 mg/kg), and low-dose group (125 mg/kg). Anesthesia time, recovery time, end-tidal peak $CO_2$ ($ETCO_2$), mean arterial blood pressure, heart rate, oxygen saturation ($SpO_2$), body temperature, pH, $PCO_2$, and $PO_2$ of the arterial blood were measured. Stable anesthesia was induced by all doses of TBE and the anesthesia time was maintained exhibited dose dependency. No significant differences in anesthetic duration were found among the three different strains. However, the anesthesia time was longer in female than in male mice, and the duration of anesthesia was significantly longer in female than in male mice in the high-dose group. The recovery time was significantly longer for female than male mice in the intermediate- and high-dose groups. In the ICR strains tested, there were no significant differences in the mean arterial blood pressure, $SPO_2$, arterial blood $PCO_2$, and $PO_2$, which decreased after TBE anesthesia, or in heart rate and $ETCO_2$, which increased after TBE anesthesia. In addition, body temperature, blood biochemical markers, and histopathological changes of the liver, kidney, and lung were not significantly changed by TBE anesthesia. These results suggested that ICR mice from different sources exhibited similar overall responses to a single exposure to TBE anesthesia. In conclusion, TBE is a useful drug that can induce similar anesthetic effects in three different strains of ICR mice.

• 디지털융복합연구
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• 제17권8호
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• pp.197-204
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• 2019

본 연구의 목적은 스마트폰 사용자들의 의사결정에 영향을 미치는 요소들을 탐구하는 것이었다. 본 연구는 친밀감, 개인연결성, 사용 및 의존성, 친숙함 및 전문성, 효능 및 효과, 자아정체성, 제어 등을 독립 변수로 설정하고 의사 결정을 종속 변수로 설정한다. 본 연구에서는 스마트폰 사용자 200명을 설문지를 통해 수집 분석하였으며, 변수간 영향을 파악하기 위해 Smartpls 3.0을 사용하였다. 스마트폰 사용자의 심리적 강도에 영향을 준 6가지 요인 중 5가지가 의사결정에 영향을 미친 것으로 분석됐다. 또한 조절변수로서의 사용 기간 등이 심리적 영향과의 관련성도 살펴보았다. 본 연구 분석 결과는 이전에 스마트폰의 심리적 영향에 대한 요인들에 연구가 미진한 가운에 스마트폰 기기의 발전 형태의 소비자 행동 기반이 될 수 있고, 향후 본 연구를 바탕으로 스마트폰 시스템 개발에 도움이 될 것으로 기대한다.

• Journal of Positioning, Navigation, and Timing
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• 제11권4호
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• pp.327-332
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• 2022

The Korea Augmentation Satellite System (KASS) is the Satellite-Based Augmentation System (SBAS) under development in Korea. KASS navigation service support navigation Safety of Life (SoL) service. KASS signal provides corrections to Global Positioning System (GPS) data received from KASS Reference Stations (KRS) and is broadcast form Geostationary Earth Orbiting (GEO) satellites to KASS users and is used by GPS/SBAS user equipment to improve the accuracy, availability, continuity and integrity of the navigation solution. Seven KRS's collect the satellite data and send them to the KASS Processing Stations (KPS) for the generation of the corrections and the monitoring the integrity. For performing its computation the KPS needs to know accurate and reliable KRS antennas coordinates. These coordinates are provided as configuration parameters to the KPS. This means that the reference frame in which the KPS work is the one represented by the set of coordinates provided as input. Therefore, the activity to maintain the accuracy of the KRS antenna coordinates is necessary, knowing that coordinates can evolve due to earth plates movements or earthquakes. In this paper, we analyzed the geodetic survey results for KRS antenna coordinates from Site Acceptance Test (SAT) #1 in December 2020 to August 2022. In the future, it is expected that these activities and planning for KRS coordinates maintenance will be produced and provided to KASS system operators for KPS configuration updates during the KASS lifetime of 15 years. Through these maintenance activities, it is expected that monitoring and analysis of unpredictable events such as earthquakes and seism will be possible in the future.

• 한국정보통신학회논문지
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• 제25권6호
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• pp.841-848
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• 2021

본 연구의 목적은 스마트폰을 사용하는 사용자들이 의사결정에 어떤 요소를 통해 영향을 미치는지 탐구하는 것이었다. 본 연구는 친밀감/개인 연결성, 사용/의존성, 친숙함/전문성, 효능/효과, 자아정체성, 제어 등을 독립변수로 설정하고 의사결정은 종속 변수로 설정하였다. 본 연구에서는 스마트폰 사용자 200명을 설문지를 통해 수집·분석하였으며, 변수 간 영향을 파악하기 위해 WarpPLS를 사용하였다. 이 연구는 사용자의 심리적인 의사결정이 스마트 기기에 어떤 요인으로 영향을 미치며, 이를 통해 미래 산업의 발전과 스마트 기기를 사용하는 사용자들의 특성과 수용성을 파악할 수 있다.

• Safety and Health at Work
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• 제14권4호
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• pp.368-374
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• 2023

Background: Recognizing that access to safe and healthy working conditions is a human right, the World Health Organization (WHO) calls for specific occupational safety and health (OSH) programs for health workers (HWs). The WHO health systems' building blocks, and the International Labour Organization (ILO), highlight the importance of information as part of effective systems. This study examined how OSH stakeholders access, use, and value an occupational health information system (OHIS). Methods: A cross-sectional survey of OSH stakeholders was conducted as part of a larger quasi experimental study in four teaching hospitals. The study hospitals and participants were purposefully selected and data collected using a modified questionnaire with both closed and open-ended questions. Quantitative analysis was conducted and themes identified for qualitative analysis. Ethics approval was provided by the University of Pretoria and University of British Columbia. Results: There were 71 participants comprised of hospital managers, health and safety representatives, trade unions representatives and OSH professionals. At least 42% reported poor accessibility and poor timeliness of OHIS for decision-making. Only 50% had access to computers and 27% reported poor computer skills. When existing, OHIS was poorly organized and needed upgrades, with 85% reporting the need for significant reforms. Only 45% reported use of OHIS for decision-making in their OSH role. Conclusion: Given the gap in access and utilization of information needed to protect worker's rights to a safe and healthy workplace, more attention is warranted to OHIS development and use as well as education and training in South Africa and beyond.

• 한국응급구조학회지
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• 제11권3호
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• pp.163-174
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• 2007

Purpose : This study analyzes prehospital care report of emergency service at prehospital stage, examines characteristics of activities of 119 paramedics and its users and aims to provide help for improving emergency system in future. Methods : Data collected were 119 prehospital care report and hospital records with 7,160 patients to emergency room by 119 ambulance from Jan. 1 to Dec. 31, 2006 and percentage and frequency of the data were obtained. Results : 1) Use of emergency room by 119 ambulance was increased in summer and autumn such as August(9.1%), September(11.2%) and October(13.5%) and it was more frequently used on Monday(17.3%), Saturday(17.2%) and Friday(16.1%) by telephone(98.6%). 2) Using emergency room was most in over sixties(51.8%), men(64.2%), community residents (78.3%), by report of family(50.3%) and at '09:01~12:00'(16.5%). 3) Symptoms of emergency room users included headache, chest pain, stomachache, lumbago and others as 40.6% and places where patients were found were at home(60.1%) due to chronic internal diseases at 49.2%. 4) Most of non-emergency patients(80.2%) arriving at hospital had normal pupil condition (88.4%) and clear consciousness(71.2%) and most of them left hospital after having first-aid treatment. 5) Physiological symptom tests evaluated by paramedics at prehospital stage included blood pressure(56.6%), pulse(22.9%), breathing(13.0%) and temperature(9.2%), and there was no SPo2 case. 6) Classification of severity by paramedics showed difference as emergency patients(18.0%) by paramedics and those(24.9%) by hospital. 7) First-aid treatments by paramedics at prehospital stage were promoting comfort(28.9%), hemostasis(7.7%), fixing cervical vertebrae(4.0%) and ensuring vein route(3.1%). 8) Selectors of medical agency were patients or guardians(86.2%) and emergency medical technicians(73.6%). Conclusion : To sum up the above research, it was found that percentage of using 119 ambulance by non-emergency patients was higher and paramedics performed basic first-aid treatment rather than professional first-aid treatment due to several conditions such as legal problems, range of allowance, etc. Therefore, it is considered that method to reduce frequency of ambulance by non-emergency patients and approaches to alleviate limitations of allowance of paramdeics to make them perform effective first-aid treatment at prehospital stage should be sought in the dimension of individual, organization and government.

• 대한간호학회지
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• 제31권1호
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• pp.31-42
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• 2001

This study was done to evaluate the effect reducing artificial dead space on intubated children. Data were collected from July 1st, 1998 to August 31st, 1999. The subjects were selected from a pediatric intensive care unit of 'S' hospital and intubated with 3.5 mm or 4.5 mm endotracheal tube after open heart surgery. They were composed of 34 patients : 17 patients were assigned to the experimental group and the rest of them were placed in the control group. The artificial airway volume was minimized in the experimental group, and the control group maintained the artificial airway volume. ETCO2, PaCO2, SPO2 were measured as indicators of pulmonary ventilation. The tools of this study were GEM-Premier and Space-Lab patient monitors. The data were analyzed using the SPSS/PC+ program. The $\chi$2 -test was used to find general characteristics. The t-test was used to test the homogenety of the pulmonary ventilation status and mechanical ventilation setting before intervention between the two groups. Also, the paired t-test was used to examine the hypothesis. The results can be summerized as : 1. CO2 can be expelled effectively from the body in case artificial dead space was decreased. 2. As the artificial dead space was reduced, the difference between ETCO2 and PaCO2 was decreased, in other words pulmonary ventilation was improved. 3. If the artificial dead space occupied above 15 percent of tidal volume, the effect of CO2 was retention revealed in the body. 4. If the artificial dead space occupied below effect. Based on the results, the following is suggested to be applied practically : 1. A kind of the ventilator circuit acting artificial dead space should be removed from the intubated children with mechanical ventilaion. 2. The endotracheal tube should not be cut because extra-body space of the endotracheal tube did not have an effect on the dead space of the intubated children. Since the researcher could not cover this aspect in the study, they recommend the following. 1. The study should be extended to the other pulmonary disease patients for the effect of improving pulmonary ventilation. 2. Also, further studying with a more narrow interval in the extra-body space of the artificial airway will be able to explain the point of artificial dead space with proper ventilation.

• 대한소아치과학회지
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• 제37권2호
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• pp.213-217
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• 2010

Chloral hydrate와 hydroxizine을 이용한 경구진정법은 적용대상의 나이와 체중에 따라 제한을 받는다. 일반적으로 경구 진정법은 36개월 미만, 체중 15 kg 미만의 환아에서 가장 좋은 진정 효과를 보인다. 그러나 36개월 이상 또는 15 kg 이상의 환아에 대해서는 경구진정법이 적절한 진정 효과를 얻는데 한계를 가지며, 얕은진정으로 인해 시술 중 잦은 움직임을 보여 쉽게 진정에 실패하게 된다. 진정 실패 시 고려 할 수 있는 대안은 추가적인 약제 투여로 인한 재진정의 유도나, 좀 더 깊은진정 법으로의 전환이 있다. 그러나 깊은진정법으로의 전환은 환아의 움직임과 동통의 감소를 위해 흡입마취제 및 마취기계가 요구되어 외래 진료실에서는 쉽게 선택되지 못한다. EMLA cream(Eutectic Mixture of Local Anesthesia)은 피부의 도포마취를 위해 널리 사용되고 있는 약제로 본 증례에서는 이를 이용하여 자극 없이 정주진정 경로를 확보하여 경구진정에서 정주진정으로의 전환에 성공하였다. 만 46개월, 체중 15 kg 남아가 다발성 우식을 주소로 단국대학교 치과대학 병원 소아치과에 내원하였다. 일반적인 행동조절 하에 치료 권유하였으나 보호자의 요구에 의해 경구진정 시도하였으며, 경구진정 실패를 고려하여 복용 전 EMLA cream을 사전 도포하였다. 경구 복용 90분 경과 뒤에도 진정효과를 얻지 못하여 보호자의 동의하에 아산화질소를 이용하여 얕은진정 유도 후, EMLA cream 도포 부위에 정맥로를 확보하였다. 총 시술 시간 2시간 30분으로 특별한 부작용 없이 성공적으로 시술을 완료하였다.

• 한국식품저장유통학회지
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• 제18권5호
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• pp.721-728
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• 2011

Camellia oil과 palmitic, 그리고 stearic ethyl ester를 기질로 하고 Lipozyme TLIM을 촉매로 이용하여 interesterification을 통한 POS를 많이 함유한 반응물을 합성하고자 하였다. 반응 조건(반응효소비율, 반응시간, 기질의 비율)을 독립변수로 하여 중심 합성 계획에 의한 반응 표면 분석을 통하여 POS의 함량은 높이고, sn-2 position의 acyl migration을 낮추어 합성하는 최적화 조건을 얻었다. POS를 많이 함유한 반응물의 합성 최적화 조건은 반응 효소양($X_1$)= 5.9%, 반응시간($X_2$)= 60 min, 그리고 기질비율($X_3$)= 1:3(1 mole의 camellia oil: 3 mole의 palmitic ethyl ester + 3 mole의 stearic ethyl ester)이었다. 이와 같은 조건으로 획득된 실재 효소반응 합성물의 TAG-P/O/S(palmitic, stearic과 oleic 지방산을 각각 1 분자씩 어느 위치이던지 함유한 TAG, 즉 POS 및 PSO/OSP/OPS/SPO)의 합성율($Y_1$)은 20.19%이었고, 이때 acyl migration 등에 의하여 sn-2 위치에 결합(이동)한 palmitic과 stearic acid의 양(P/S-sn-2)인 $Y_2$는 12.71% 이었다.

• 대한전자공학회논문지TC
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• 제42권12호
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• pp.127-134
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• 2005

VoIP에서 패킷의 손실은 음성의 품질에 영향을 주는 가장 중요한 요인이다. 따라서 수신된 정보로부터 손실된 패킷을 복구하는 것은 중요하다. 따라서 본 논문은 VoIP에서 가장 많이 사용되는 CELP 부호화기를 위한 수신측 기반의 손실 패킷 복구방법을 제안한다. 제안하는 WSOLA(Waveform Shift OverLab Add)기반의 BS-PLC (Both Side Packet Loss Concealment) 방법은 패킷 손실이 발생하였을 경우 미래 패킷을 이용할 수 있는 경우와 그렇지 않을 경우로 나누고, LP(Linear prediction) 파라미터와 여기 신호를 복구한다. 미래 패킷을 이용할 수 없는 경우에는 과거에 전송된 정상 패킷만을 가지고 복원을 하며, 미래 패킷을 이용할 수 있을 경우에는 과거의 정상 패킷과 미래의 정상 패킷을 동시에 이용하여 손실된 패킷을 복구한다. 연속 패킷 손실 환경은 Gilbert 모델로 설정하였고, 제안한 알고리즘을 VoIP에서 가장 많이 사용되는 CELP 음성부호화기인 G.729에 적용하여 성능을 비교한다. 성능 비교를 위해 손실율을 변화시키면서 SNR(Signal to Noise)와 MOS(Mean Opinion Score)측정하였고, 제안한 방법을 G.729의 패킷 손실 은닉 방법과 비교하였다. 실험 결과, 평균 손실률이 $20\%$에서도 SNR은 2dB, MOS값은 0.3정도로의 음질 개선을 보였다.