• Journal of Dental Anesthesia and Pain Medicine
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• v.24 no.5
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• pp.305-318
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• 2024

This study aims to compare the analgesic efficacy of dexketoprofen trometamol (DT) with other analgesic drugs for pain relief after third molar surgery. The PubMed, Scopus, and Web of Science databases were searched to identify randomized controlled trials comparing DT with other analgesics for third molar surgery. The outcome measures were the sum of pain intensity differences (SPID), total pain relief (TOTPAR) at the 6^th and 8^th postoperative hours, time to rescue medication, and tolerability. In total, four studies met our inclusion criteria. A total of 660 third molar surgeries were performed: 365 in the DT group and 295 in the active control group. Compared to other analgesics, DT produced significantly better pain relief at the 6^th postoperative hour: SPID (MD, 0.33; P = 0.01) and TOTPAR (MD, 0.41; P = 0.02). However, there were no statistically significant differences in the efficiency of pain relief at the 8^th postoperative hour, time to rescue medication, or tolerability. Overall, a 25 mg dose produced the best results for pain relief. In conclusion, DT (25 mg) is a viable alternative to contemporary analgesics for pain relief after third molar surgery, particularly during the early postoperative period.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.8
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• pp.352-362
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• 2016

Today, it appears that the rapid advances in technology have allowed broadening both the system technology and the business opportunities in the rail industry. Owing to the developments in technology and the industry, and also due to the hearth, the latest high-speed trains and a variety of unattended operations in rail systems are being developed and are operational. In particular, this study covers the existing railway rolling stock and signaling systems that operate in an environment more complex than the concept of localized management, so the introduction of a new signaling system is needed. In addition, developments based on the existing signal system concepts for passenger railways need to minimize human injury. In this study, to participate in the development of new systems in a variety of domains and to provide an integrated common vision methodology as an engineer on the basis of efficient signal system design and safety would like to present the methodology for action. Therefore, each different linkage through the next new domain zone system design: design through to secure the integrity of safety than can secure methodology.