• Transactions of the Korean Society of Mechanical Engineers A
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• v.32 no.1
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• pp.13-20
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• 2008

The purpose of this study is to investigate the effect of acid fog on the rust formation behavior of weathering steel (SMA50) which is used in un-coated bridges. Weathering steel didn't form the passive film under the environment of acid fog(pH5,6), whereas the environment of distilled water formed the protective oxide film. Therefore, the construction of weathering steel under the environment extremely exposed to SOx and NOx which are the main compositions of acid fog is not adequate. Fatigue limits of weathering steel under acid fog environment are remarkably decreased as compared with environment of distilled water. The corrosive constituents in acid fog has piled up the corrosion products on specimen surface and generated the corrosion pits. Because of the high stress concentration arising at this corrosion pit, relatively low fatigue limits were obtained for acid fog specimens.

• Journal of Korean Society for Atmospheric Environment
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• v.15 no.5
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• pp.587-598
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• 1999

In recent years emissions of pollutants from ship sources, especially NOx and SOx, is controlled by IMO(International Maritime Organization). The emissions of pollutants from ship sources in Pusan is considerably large, because the number of ship's coming and going in Pusan port is larger than that of other ports in Korea. Since Pusan is under the strong influence of land-sea breezes, pollutants emitted from ship sources will be transported into the inland. Control of emissions from ship sources is required to devise effectively the policy of air quality management in Pusan. Therefore this paper considered the present condition of total pollutant sources and emission characteristics including in coastal urban area.

• The Transactions of the Korean Institute of Electrical Engineers C
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• v.53 no.5
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• pp.264-267
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• 2004

Recently the pulsed power systems have been widely used in many fields such as E/P(Electrostatic Precipitator), DeNOx/DeSOx power systems, ozone generators and power sources of the laser beam. In this paper, we studied various electrical characteristics for arc suppression of line-to-line electrodes in air and removal of the metaloxide using our pulsed power system. To obtain high efficiency of the pulsed power system, we repeatedly experimented and tested their characteristics. by adjusting electrode length of the load. As a result, when the value of the electrode length and pulse repetition rate were changed at the load, the value of the arc voltage changed at the electrode load. In conclusion, we controlled arc voltage of the load by ,changing electrode length and pulse repetition rate. Also. we stydied removal area of the metaloxide using area discharge according to pulse repetition rate.

• Journal of Ocean Engineering and Technology
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• v.33 no.5
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• pp.447-453
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• 2019

Recently, environmental regulations have been strengthened for SOX, NOX, and CO2, which are ship exhaust gases. In addition, according to the 4th Industrial Revolution, research on autonomous ship technology has become active and interest in electric propulsion systems is increasing. This paper analyzes the power load characteristics of an electric propulsion ship, which is the basic technology for an autonomous ship, in terms of energy management. For the load analysis, data were collected for a 6,800 TEU container ship with a mechanical propulsion system, and the propulsion load was converted to an electric power load and clustered according to the characteristics using a SOM (Self-Organizing Map). As a result of the load analysis, it was confirmed that the load characteristics of the ship could be explained by the operation mode of the ship.

• Genomics & Informatics
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• v.17 no.1
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• pp.8.1-8.10
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• 2019

Alveolar type II cells constitute a small fraction of the total lung cell mass. However, they play an important role in many cellular processes including trans-differentiation into type I cells as well as repair of lung injury in response to toxic chemicals and respiratory pathogens. Transcription factors are the regulatory proteins dynamically modulating DNA structure and gene expression. Transcription factor profiling in microarray datasets revealed that several members of AP1, ATF, $NF-{\kappa}B$, and C/EBP families involved in diverse responses were expressed in mouse lung type II cells. A transcriptional factor signature consisting of Cebpa, Srebf1, Stat3, Klf5, and Elf3 was identified in lung type II cells, Sox9+ pluripotent lung stem cells as well as in mouse lung development. Identification of the transcription factor profile in mouse lung type II cells will serve as a useful resource and facilitate the integrated analysis of signal transduction pathways and specific gene targets in a variety of physiological conditions.

• Prospectives of Industrial Chemistry
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• v.22 no.5
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• pp.41-50
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• 2019

2020년 1월 1일부터 이행되는 연료유의 황 함유량 규제에 따른 대응 현황을 보면, 약 60% 이상의 선사들이 저유황유 사용을 고려하고 있다. 이처럼 높은 저유황유 선택에 따라 저유황유의 안정적인 공급에 대한 사전 검토 및 대비책을 통한 구체적인 방안이 요구되고 있으며, 저유황유의 품질 보증이 무엇보다도 중요한 사안이라 판단된다. 저유황유의 품질에 따라 예상되는 문제점을 미리 파악하고 이에 대한 적절한 대응 방안을 수립하여 선박 기관 운영에 차질이 없도록 대비하여야 한다. 그래서 선박에 공급되는 저유황유의 품질 특성 시 고려사항을 전달하고자 한다.

• Molecular & Cellular Toxicology
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• v.3 no.4
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• pp.231-237
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• 2007

Exposure to DNA-damaging agents can elicit a variety of stress-related responses that may alter the expression of genes associated with numerous biological pathways. We used 19 k whole human genome chip to detect gene expression profiles and potential signature genes in human normal hepatocytes (THLE-3) by treatment of five direct acting mutagens, furylfuramide (AF-2), N-nitroso-N-methylurea (MNU), methylmethanesulfonate (MMS), 4-nitroquinoline-N-oxide (4-NQO) and 2-nitrofluorene (2NF) of the $IC_{20}$ concentration for 3 h. Fifty one up-regulated common genes and 45 down-regulated common genes above 1.5-fold by five direct-acting mutagens were identified by clustering analysis. Many of these changed genes have some association with apoptosis, control of cell cycle, regulation of transcription and signal transduction. Genes related to these functions, as TP73L, E2F5, MST016, SOX5, MAFB, LIF, SII3, TFIIS, EMR1, CYTL1, CX3CR1 and RHOH are up-regulated. Down-regulated genes are ALOX15B, xs155, IFITM1, BATF, VAV2, CD79A, DCDC2, TNFSF8 and KOX8. We suggest that gene expression profiling on mutagens by toxicogenomic analysis affords promising opportunities to reveal potential new mechanistic markers of genotoxicity.

• Corrosion Science and Technology
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• v.20 no.5
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• pp.266-280
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• 2021

Since 2020, the International Maritime Organization (IMO) has updated regulations on the sulfur content to be less than 0.5% in exhaust gas emitted from ships. Accordingly, the exhaust gas post-treatment device for ships, which is SOx/NOx reduction technology, was introduced. However, the exhaust gas post-treatment device is suffering corrosion because of the harsh corrosive environment formed by sulfate and chlorine oxide through the desulfurization process. In this investigation, cyclic potentiodynamic polarization (CPDP) experiment for UNS S31603 and UNS N08367 was performed in a green death solution that simulates the environment of a desulfurization device. The corrosion rate of UNS S31603 at the highest temperature was about 3 times higher than that of UNS N83067. Also, electron microscope scan revealed corrosion type UNS N83067 presents intergranular corrosion tendency. On the other hand, UNS S31603 was observed as general corrosion. The α values of UNS N08367 at 30 ℃ and 60 ℃ were higher than those of UNS S31603, thus UNS N08367 is considered to have a higher local damage tendency. Whereas, since the α value of UNS S31603 at 90 ℃ is larger than that of UNS N08367, UNS S31603 is considered to have a higher local damage trend.

• Natural Product Sciences
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• v.27 no.3
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• pp.161-168
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• 2021

The chemical investigation of the 90% EtOH extract from Cicadidae Periostracum led to the isolation and identification of seven known N-acetyldopamine dimers (1-7). These compounds were identified by comparing mass spectrometry data and NMR spectroscopic data with those previously reported. In this study, complete interpretation of 1D and 2D NMR data of 1 and 2 were reported for the first time. In addition, compounds 3 and 4 were isolated from this material for the first time. All isolates were obtained as racemic mixtures, as confirmed by chiral HPLC. Furthermore, we evaluated the neuroprotective activities of compounds 1-7 and found that compounds 1, 5, and 6 significantly attenuated rotenone-induced death of SH-SY5Y neuroblastoma cells at a concentration of 100 μM. Parallel to this result, compounds 3 and 6 displayed antioxidant effects in the cytoplasm, as determined by CM-H2DCFDA fluorescence intensity, while compounds 1 and 5 showed antioxidant effects in the mitochondria, as assessed by MitoSox fluorescence intensity. Overall, these results suggest that some of these compounds protect neuroblastoma cells by ameliorating the release of reactive oxygen species. Further studies are warranted to elucidate the underlying mechanisms by which these compounds exhibit antioxidant and neuroprotective actions.

• Journal of Interdisciplinary Genomics
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• v.5 no.2
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• pp.18-23
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• 2023

Conventional evaluation method for identifying the organic cause of short stature has a low detection rate. If an infant who is small for gestational age manifests postnatal growth deterioration, triangular face, relative macrocephaly, and protruding forehead, a genetic testing of IGF2, H19, GRB10, MEST, CDKN1, CUL7, OBSL1, and CCDC9 should be considered to determine the presence of Silver-Russell syndrome and 3-M syndrome. If a short patient with prenatal growth failure also exhibits postnatal growth failure, microcephaly, low IGF-1 levels, sensorineural deafness, or impaired intellectual development, genetic testing of IGF1 and IGFALS should be conducted. Furthermore, genetic testing of GH1, GHRHR, HESX1, SOX3, PROP1, POU1F1, and LHX3 should be considered if patients with isolated growth hormone deficiency have short stature below -3 standard deviation score, barely detectable serum growth hormone concentration, and other deficiencies of anterior pituitary hormone. In short patients with height SDS <-3 and high growth hormone levels, genetic testing should be considered to identify GHR mutations. Lastly, when severe short patients (height z score <-3) exhibit high levels of prolactin and recurrent pulmonary infection, genetic testing should be conducted to identify STAT5B mutations.