• 한국식품과학회지
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• 제30권6호
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• pp.1464-1469
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• 1998

3-Chloro-1,2-propanediol (3-MCPD), 1,3-dichloro-2-propanol (1,3-DCP), 2,3-dichloro-1-propanol (2,3-DCP)과 같은 chloropropanol들이 일부 식품에서 검출됨으로서 위해성 논란이 제기되었기에 본 연구에서는 Ames test와 SOS Chromotest를 이용하여 미생물 시험계에서의 chloropropanol류의 유전독성 및 변이원성을 검토하였다. E. coli PQ37에서는 1,3-DCP를 제외한 3-MCPD와 2,3-DCP는 뚜렷한 용량반응 관계를 보이며 SOS반응 유도활성을 나타내어 유전독성이 있는 것으로 판단되었고 3-MCPD보다는 2,3-DCP가 강한 유도활성을 나타내었다. 또한 E. coli PQ35 (PQ37 $uvrA^+)$에서는 SOS반응 유도활성이 E. coli PQ37에서 보다 매우 낮은 반면에, E. coli PQ243 (PQ37 tagA alkA)에서는 매우 높게 나타남으로서 이들 물질에 의하여 유도되는 DNA 손상은 절제수복에 의해 수복될 수 있는 손상과 절제수복에 의해 수복되지 않으며 adaptive response를 유도할 수 있는 3-methyladenine 또는 이와 유사한 손상 등이 작용하는 것으로 나타났다. S. typhimurium TA100을 이용한 Ames test에서도 3-MCPD와 2,3-DCP는 뚜렷한 용량반응 관계를 보이며 강한 돌연변이원성을 나타내었으나 SOS Chromotest에서와는 달리 1,3-DCP 또한 돌연변이원성을 나타냈으며, 변이활성정도는 2,3-DCP>3-MCPD>1,3-DCP의 순으로 나타났다. 그러나 S. typhimurium TA98과 TA97a에서는 돌연변이활성이 미미하게 나타남으로서 chloropropanol류에 의한 돌연변이는 주로 염기치환에 의한 작용임을 알 수 있었다. 한편, S. typhimurium TA1535 (-R factor plasmid)에서 3-MCPD와 2,3-DCP의 돌연변이활성이 S. typhimurium TA100에 있어서 보다 상당히 낮은 결과로부터 이들 물질에 의한 돌연변이 유발은 주로 SOS수복 의존성인 것으로 나타났다. Amestest와 SOS Chromotest의 결과를 종합하여 볼 때 3-MCPD와 2,3-DCP는 3-methyladenine 또는 이와 유사한 DNA 손상에 의한 SOS수복 비의존성 돌연변이 및 SOS반응 유도성 손상, 특히 절제회복에 의해 쉽게 제거될 수 있는 손상에 의한 SOS수복 의존성 돌연변이를 동시에 일으키는 것으로 사료된다.

• 생명과학회지
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• 제5권3호
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• pp.121-125
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• 1995

To determine whether the omega 3 family, linolenic acis(LnA) is effective to inhibit carcinogens/mutagens-induced mutagenesis, we employed the Ames test using Salmonella typhimurium strain of TA100 and the SOS chromotest using Escherichia coli PQ37 strain. The inhibitory effect of LnA shown in the Ames assaying system was 95%, 78% and 73% when the mutagenicities were mediated by AFB$_{1}$, MNNG and 4-NQO, respectively. LnA shows a strong antimutagenic activity against indirect mutagen of AFB$_{1}$, whereas the same concentration of LnA exhibited weaker inhibitory effects on the direct mutagen of MNNG and 4-NQO than that of AFB$_{1}$. However. LnA reduced more than 80% of SOS responses induced by MNNG and 4-NQO when the adding concentration increased to 5%. We conclude that LnA contains in vitro antimutagenic properties and that this finding warrants further investigation both in vitro and in vivo to assess its possible chemotherapeutic potential.

• ETRI Journal
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• 제22권1호
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• pp.1-11
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• 2000

The Satellite Operation System (SOS) has been developed for a low earth orbiting remote sensing satellite, Korea Multipurpose Satellite-I, to monitor and control the spacecraft as well as to perform the mission operation. SOS was designed to operate on UNIX in the HP workstations. In the design of SOS, flexibility, reliability, expandability and interoperability were the main objectives. In order to achieve these objectives, a CASE tool, a database management system, consultative committee for space data systems recommendation, and a real-time distributed processing middle-ware have been integrated into the system. A database driven structure was adopted as the baseline architecture for a generic machine-independent, mission specific database. Also a logical address based inter-process communication scheme was introduced for a distributed allocation of the network resources. Specifically, a hotstandby redundancy scheme was highlighted in the design seeking for higher system reliability and uninterrupted service required in a real-time fashion during the satellite passes. Through various tests, SOS had been verified its functional, performance, and inter-face requirements. Design, implementation, and testing of the SOS for KOMPSAT-I is presented in this paper.

• 한국동물위생학회지
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• 제13권1호
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• pp.21-26
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• 1990

This survey was carried out to determine sulfamethazine residues in urine, kidney and muscle of slaughtered pigs. For this investigation, 20 samples for export and 30 samples for domestic market were collected at slaughterplant in Anyang city from the early of November to the end of December and comparatively were analyzed by SOS test kit and HPLC the results obtained were summarized as follows : 1. Five of 50 samples of swine urine which were inspected by SOS test kit were appeared to sulfamethazine positive 2. The sulfamethazine residue In one of 50 samples of swine muscle was exceeded 0.1ppm 3. The positive samples by SOS test kit were agreed with the results of HPLC quantitative analysis

• 인터넷정보학회논문지
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• 제21권6호
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• pp.113-121
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• 2020

The era of "ownership" has gone, and the era of "subscription" has come. While traditional manufacturing and service industries are struggling with the fall of earnings rates, subscription-based businesses are showing high growth rates. Although subscription-based online services (SOS) are rapidly growing in the retail market, few studies have investigated factors that affect the decision of consumers to use SOS. Therefore, this study aims to identify factors that enable predicting consumers'attitudes and intentions toward SOS and to empirically verify the factors. As a result of the study, usefulness, enjoyment, and cost advantages were shown to have positive effectson perceived value, and usefulness, technicality, and cost advantages were shown to have positive effects on attitudes. In addition, perceived value was shown to have positive effects on attitude, and perceived value and attitudes were shown to have positive effects on acceptance intentions. The fact that the strategic directivity for successful introduction and diffusion of SOS was presented by identifying the predictor variables for the acceptance of SOS through this study can be said to be the significance of this study.

• 한국CDE학회논문집
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• 제14권1호
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• pp.60-68
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• 2009

Because of the reduced product life-cycle, industries are making an effort to bring down the process planning time. In the traditional approach, we have to analyze established process planning, then design the time chart based on process information and drawing the formal time chart such as SOP(sequence of operation). Thereafter, it will be converted to PLC code that is a time consuming and redundant job. Similarly, Industrial automated process uses PLC Code to control the factory; however, control information and control code(PLC code) are difficult to understand. Hence, industries prefer writing new control code instead of using the existing one. It shows the lack of information reusability in the existing process planning. As a result, to reduce this redundancy and lack of reusability, we propose SOS-Net modeling method. Unlike past stabilized process planning that is rigid to any change; our proposed SOS-Net modeling method is more adaptable to the new changes. The SOS-Net model is easy to understand and easy to convert into PLC Code accordingly. Therefore, we can easily modify the control information and reuse it for new process planning. The proposed model plays an intermediary role between process planning and PLC code generation. It can reduce the process planning and implementation time as well as cost.

• 방사선산업학회지
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• 제7권2_3호
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• pp.109-113
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• 2013

In a previous study, a relatively high dose of gamma radiation (1 kGy) did not fully induce typical SOS genes such as sulA, recA, recN, and din in Salmonella Typhimurium (S. Typhimurium) (Lim et al. 2008, Gene expression profiles following high-dose exposure to gamma radiation in Salmonella enterica serovar Typhimuium. J. Radiat. Ind. 3:111-119). In this study, we examined changes in the transcriptional repertoire of S. Typhimurium after a dose of 10 Gy using DNA microarrays. It was found that more than half (~65%) of the 26 up-regulated genes belong to the SOS regulon: ten genes are typical SOS genes, and seven genes are Salmonella prophage genes, which are known to be activated by LexA cleavage. Among 29 down-regulated genes, the function of five genes with the most decreased expression is associated with carbohydrate transport and energy production. This suggests that upon exposure to gamma radiation cells may cease growing by reducing the metabolic activity, and repair DNA damage using a DNA repair system such as the SOS response system. The difference in expression of the SOS genes between a high (1 kGy) and low (10 Gy) dose of radiation shows the possibility that cells may opt for one of multiple regulatory circuits in response to the specific gamma radiation dose.

• Journal of Preventive Medicine and Public Health
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• 제34권4호
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• pp.408-416
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• 2001

Objectives : To evaluate the diagnostic value of quantitative ultrasound (QUS) in the prediction of osteoporosis as defined by dual energy x-ray absorptiometry (DEXA) in postmenopausal women. Methods : Questionnaires and height and weight measurements were used in the investigation of 176 postmenopausal women. QUS measurements were taken on the right calcaneus while bone mineral density (BMD) measurements of the lumbar spine and femoral neck were made with DEXA. The areas under the curves (AUC) of the speed of sound (SOS) for osteoporosis in the lumbar spine and femoral neck were obtained through receiver operating characteristic (ROC) analysis and evaluated. A comparison was made, for osteoporosis in the lumbar spine and femoral neck, between the AUCs of the logistic model with clinical risk factors and SOS. Results : Pearson's correlation coefficients of SOS and lumbar spine BMD, and of SOS and femoral neck BMD were 0.26 and 0.37. The AUC for the logistic model in its discrimination for lumbar spine osteoporosis was 0.764, and for SOS 0.605. The AUCs for the logistic model in its discrimination for femoral neck osteoporosis and for SOS were 0.890 and 0.892, respectively. Conclusions : These results suggest that the diagnostic value of QUS as a screening tool for osteoporosis is moderate for the femoral neck, but merely low for the lumbar spine and that the predictability provided by SOS is no better than that by the sole use of clinical risk factors in postmenopausal women.

• Journal of Nutrition and Health
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• 제39권2호
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• pp.171-183
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• 2006

This study was conducted to examine dietary factors affecting bone status in the rural aged men. Quantitative ultrasound measurements (QUS) of bone, that may reflect certain architectural aspects of bone, have been shown to be associated with bone mineral density and fracture. Information of diet and anthropometry was collected in 164 aged men. Dietary intake data were obtained by 24-hour recall method. Measurements of the speed of sound (SOS, m/s), at distal radius, mid-tibia, phalanx, were performed using Omnisense 7000S analyzer (Sunlight Ltd., Tel Aviv, Israel). T-scores for bone SOS measurements at distal radius, mid-tibia and phalanx were 0.60, 0.03 and -0.42 respectively. The prevalence of osteopenia by use of the WHO criteria was 17.7% at the mid-tibia and 25.3% of the subjects at the distal radius. Age were negative association with bone SOS at three sites. Osteopenia group of radius were significantly lower in total foods and vegetable intakes than normal group. After adjusted for age, vegetable intakes were significantly and positively related to bone SOS at the radius. The bone SOS of the tibia were significantly and positively related to vegetable protein, iron, folate and vegetable intakes, but negatively related to fat intakes. Multiple regression analysis showed that bone SOS of tibia was positively associated with folate intakes. Vegetable intakes were positively associated with the bone SOS at three sites. These results indicate that the consumption of vegetables, sources of folate, may have a effect on bone status of men.

• 한국식품영양과학회지
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• 제33권6호
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• pp.930-935
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• 2004

Ames test와 SOS chromotest를 이용하여 유기 게르마늄과 게르마늄을 첨가하여 재배한 콩나물의 항돌연변이 효과를 검토하였다. 균주 Salmonella typhimurium TA100에서 AFB$_1$에 의하여 유발된 돌연변이는 Ge-132와 게르마늄 가루에 의하여 농도 의존적으로 저해 효과가 높게 나타났으며, 특히 유기 게르마늄을 20 mg/plate 첨가하였을 때 대조군에 비하여 87%의 돌연변이 유발 억제율을 나타내었다. 똑같은 실험계에서 게르마늄을 첨가하여 재배한 콩나물의 즙액과 methanol 추출물은 수돗물로 재배한 콩나물에 비하여 돌연변이 유발억제 작용이 유의적으로 높게 나타났다. 또한 직접돌연변이원인 MNNG와 4-NQO에 의해 유발된 돌연변이는 일반콩나물의 즙액을 200 $\mu$L/plate 첨가하였을 때 각각 37∼39%, 38∼48%의 저해효과를 나타낸 반면 같은 농도에서 게르마늄 콩나물의 즙액은 61%와 75%의 억제율을 나타내어 게르마늄 첨가 콩나물은 간접 돌연변이원뿐만 아니라 직접 돌연변이원에 의해서 유발된 돌연변이도 억제함을 알 수 있었다. 한편 E. coli PQ37 균주를 사용한 SOS chromotest에서 유기 게르마늄은 사용된 농도의 증가에 따라 돌연변이 유발억제작용이 증가하였으며, 게르마늄 콩나물의 methanol 추출물은 일반 콩나물에 비하여 높은 돌연변이 유발 억제작용을 나타내었다. 따라서 Ames test와 SOS chromotest를 통하여 게르마늄을 첨가하여 재배한 콩나물은 수돗물로 재배한 콩나물에 비하여 항돌연변이 효과가 우수한 것을 알 수 있었다.