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The Effects of Puerariae Flos on Stress-induced Deficits of Learning and Memory in Ovariectomized Female Rats

  • Park, Hyun-Jung;Han, Seung-Moo;Yoon, Won-Ju;Kim, Kyung-Soo;Shim, In-Sop
    • The Korean Journal of Physiology and Pharmacology
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    • v.13 no.2
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    • pp.85-89
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    • 2009
  • Puerariae flos (PF) is a traditional oriental medicinal plant and has clinically been prescribed for a long time. The purpose of the present study was to examine the effect of PF on repeated stress-induced alterations of learning and memory on a Morris water maze (MWM) test in ovariectomized (OVX) female rats. The changes in the reactivity of the cholinergic system were assessed by measuring the immunoreactive neurons of choline acetyltransferase (ChAT) in the hippocampus after behavioral testing. The female rats were randomly divided into four groups: the nonoperated and nonstressed group (normal), the sham-operated and stressed group (control), the ovariectomized and stressed group (OS), and the ovariectomized, stressed and PF treated group (OSF). Rats were exposed to immobilization stress (IMO) for 14 d (2 h/d), and PF (400 mg/kg, p.o.) was administered 30 min before IMO stress. Results showed that treatments with PF caused significant reversals of the stress-induced deficits in learning and memory on a spatial memory task, and also increased the ChA T immunoreactivities. In conclusion, administration of PF improved spatial learning and memory in OVX rats, and PF may be useful for the treatment of postmenopausal-related dementia.

Numerical Model Application for Analysis of Flood Level Mitigation due to Retention-Basin (강변저류지 홍수위 저감효과 분석을 위한 수치모형 적용)

  • Cho, Gilje;Rhee, Dong Sop;Kim, Hyung-Jun
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.15 no.1
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    • pp.495-505
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    • 2014
  • The retention basin is a river-facility for the flood mitigation by storing the river flow temporarily. The new 3 retention basins are installed in these regions YeoJu, NaJu, YoungWol by the Large River Management Project. In this study, 1D and 2D numerical flow simulation are conducted to evaluate the reduction effect of the peak flood stage for the YeoJu retention basin. HEC-RAS and FLDWAV models are used for 1D simulation with the option of retention basin. CCHE2D model is used for 2D simulation with the same hydrograph used in 1D simulation. It is verified that the peak flood stage is reduced very largely about 0.13 m near the overtopping section of the levee in 1D simulation. It is verified that the peak flood stage is reduced very largely about 0.20 m at the upstream-end of the simulated reach in 2D simulation. 2D simulation for the retention basin is more reasonable because physical characteristics of topography in the model, and also more advantageous for the evaluation of the flow characteristics of the in- and outside of the retention basin on the results of simulation of this study.

Changes in China's Rare Earth Industry Policy and their Implications (중국 희토류산업정책의 변화와 정책적 함의)

  • PARK, In-Sop;SONG, Jae-Do
    • THE INTERNATIONAL COMMERCE & LAW REVIEW
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    • v.71
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    • pp.297-324
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    • 2016
  • China not only has the largest amount of rare earth reserves, but it also produces the most rare earth products. However, China lacks appropriate supervision and management systems of its rare earth industry. The Chinese government's inappropriate mechanisms have been cause for reckless development by national rare earth providers characterized by excessive competition, environmental pollution, and smuggling. In response to the problems, China implemented regulatory measures to restructure the rare earth industry. The Chinese central government intensifies its efforts to control the total quantity of rare earth products and tackle environmental pollution. Six leading conglomerates have been selected to promote the Chinese central government's policy. A new environmental guideline has been drawn up to reduce the discharging of wastewater and air pollution substance. Huge transition and a great influence of its policy changes are expected. These policy changes are bound to entail huge transitions, and the policy is expected to have a great influence in the future structure of the rare earth industry. In consideration of these changes, the Korean government, in collaboration with private enterprises needs to take appropriate measures, such as overseas resources development, R&D expansion, tactical stockpiling, professional manpower training and so on.

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Development of Web-based Simulator for Hydrogen Station (수소충전소 웹기반 가상교육 시뮬레이터 개발)

  • Kim, Eun-Yong;Kim, Jin-Kyung;Lee, Yeong-Hui;Kim, Eun-Jung;Kim, Young-Gyu;Moon, Il
    • Proceedings of the Korea Society for Energy Engineering kosee Conference
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    • 2008.04a
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    • pp.117-122
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    • 2008
  • 본 연구에서는 수소 경제의 핵심 인프라 시설인 수소 충전소의 조업자 안전 운전을 위한 교육 및 훈련 프로그램을 구축하였으며, 개발된 프로그램은 크게 수소안전교육 모듈, 수소 충전소 가상체험 모듈, 가상 사고 시나리오 모듈로 구성되어 있다. 수소안전교육 모듈에서는 수소 사고의 특징과 안전 물성 등의 자료를 수록함으로써 수소에 안전에 대한 이해를 돕도록 하였으며, 가상체험 모듈에서는 충전소의 구성과 용도를 3D Virtual Reality 기술을 도입해 간접 체험할 수 있도록 하였다. 또한 가상사고 모듈에서는 수소 충전소에서 일어날 수 있는 사고에 대한 동적 모사를 수행하여 사고의 전개 과정 및 결과를 체험해 볼 수 있도록 하였다. 이와 함께 사고가 일어났을 경우 신속하고 정확한 대응을 통해 피해를 최소화하기 위한 ERP(Emergency Response Plan)과 SOP(Standard Operating Procedure)를 개발하였다.

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3D Depth Measurement System based on Parameter Calibration of the Mu1ti-Sensors (실거리 파라미터 교정식 복합센서 기반 3차원 거리측정 시스템)

  • Kim, Jong-Man;Kim, Won-Sop;Hwang, Jong-Sun;Kim, Yeong-Min
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2006.05a
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    • pp.125-129
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    • 2006
  • The analysis of the depth measurement system with multi-sensors (laser, camera, mirror) has been done and the parameter calibration technique has been proposed. In the proposed depth measurement system, the laser beam is reflected to the object by the rotating mirror and again the position of the laser beam is observed through the same mirror by the camera. The depth of the object pointed by the laser beam is computed depending on the pixel position on the CCD. There involved several number of internal and external parameters such as inter-pixel distance, focal length, position and orientation of the system components in the depth measurement error. In this paper, it is shown through the error sensitivity analysis of the parameters that the most important parameters in the sense of error sources are the angle of the laser beam and the inter pixel distance.

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Real-Time Neural Networks for Information Propagation of Load Vehicles in Remote (원격지 자동차의 정보 전송을 위한 실시간 신경망)

  • Kim, Jong-Man;Kim, Won-Sop;Sin, Dong-Yong;Kim, Hyong-Suk
    • Proceedings of the KIEE Conference
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    • 2003.07d
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    • pp.2130-2133
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    • 2003
  • For real-time recognizing of the load vehicles a new Neural Network algorithm is proposed. The proposed neural network technique is the real time computation method through the inter-node diffusion. In the network, a node corresponds to a state in the quantized input space. Each node is composed of a Processing unit and fixed weights from its neighbor nodes as well as its input terminal. The most reliable algorithm derived for real time recognition of vehicles, is a dynamic programming based algorithm based on sequence matching techniques that would process the data as it arrives and could therefore provide continuously updated neighbor information estimates. Through severa simulation experiments, real time reconstruction nonlinear image information is Processed. 1-D hardware has been composed and various experi with static and dynamic signals have implemented.

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A Study on Contents for Safety Training of the Thermal Power Plant to be Applied by Story Viewing (스토리 뷰잉(Story-viewing)을 적용한 화력발전분야 안전교육 콘텐츠 연구)

  • Kim, Yoo-sik;Min, Seol-hui;Seong, Yun-hak;Park, Yeong-jae
    • Fire Science and Engineering
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    • v.30 no.3
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    • pp.62-66
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    • 2016
  • There have been happening small and big fires due to the various causes in the thermal power plants which are the high risk buildings with the high possibility of big sizes of accidents, so the people in the power plants distribute the workers "the site action manuals in thermal power plants" and try to minimize the rate of disasters like fires through the regular education and training. However, in the Five Thermal Power Plants in Korea, there are no the standard of "the site action manuals" and Furthermore, the present educational manuals are mostly the hard copies with poor readability. So the standardization of the manuals are definitely needed. Therefore, in this research, we proceed the standardization of the manuals for the five areas of the site action manual s in the thermal power plants which are oil fires, electric fires, building fires, facility fires and gas leaking reaction SOP to improve the reaction power on the disasters in the power plants which are the national significant infrastructures, thus by using the manual, we propose the safety education contents for the thermal power plants based on the visualization technology using story-viewing method to complement the hard copy type disaster manuals.

Analysis of the vegetation effects on the flow in Chopyeong Island of the Imjin River using a HEC-RAS 2D model (HEC-RAS 2D 모형을 이용한 임진강 초평도 식생이 흐름에 미치는 영향 분석)

  • Lee, Du Hana;Rhee, Dong Sop
    • Journal of Korea Water Resources Association
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    • v.56 no.9
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    • pp.575-586
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    • 2023
  • River vegetation has important functions such as providing a habitat for the river ecosystem and physical stability of the river bank. It also has adverse effects such as aggravating flood damages due to the increase in roughness coefficient and drag forces. River vegetation management is very important in finding a balance between flood and ecological management. There are still many uncertainties about the effect of vegetation on rivers. In this study, in order to analyze the effect of vegetated flow, the flow patterns according to the vegetation roughness are analyzed through a two-dimensional unsteady flow model for Chopyeong island of the Imjin River. According to the results of the 2D flow analysis using the HEC-RAS 2D model, the velocity distribution in the bend of the Imjin River was greatly affected by the vegetation roughness of Chopyeong Island. The formation of the main flow outside the bend of Chopyeong Island during flooding is presumed due to the influence of tree and grass on Chopyeong Island. If tree are distributed throughout Chopyeong Island, the velocity outside the bend is expected to be higher. River vegetation causes the effect of raising the water level, and could cause a change in the velocity distribution.

Taxonomic Investigations on Korean Higher Fungi(VI) (한국산(韓國産) 고등(高等) 균류(菌類)의 분류학적(分類學的) 연구(硏究)(제6보)(第6報))

  • Park, Wan-Hee;Min, Kyung-Hee;Kim, Yang-Sop;Park, Yong-Hwan;Kim, Byung-Kak
    • The Korean Journal of Mycology
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    • v.16 no.4
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    • pp.226-229
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    • 1988
  • More than one-hundred-twenty specimens of Basidiomycetes, Ascomycetes and slime molds were collected in Seoul National Polytechnic University Campus during the priod from June 1984 to November 1987 and examined for identity. They were classified into 25 families, 53 genera and 81 species. Among them, one genus and 2 species were confirmed as unrecorded taxa in Korea. The unrecorded genus was genus Hapalopilus and was named 'Band Dal Busut' in vernacular. The unrecorded 2 species were Hapalopilus rutilans and Hygrophorus nitratus. They were named 'No Lan Ban Dal Busut' and 'Jil San Beot Geot Busut,' respectively and their characteristics were here reported.

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The Protective Effect of Black Ginseng Against Transient Focal Ischemia-induced Neuronal Damage in Rats

  • Park, Hyun-Jung;Shim, Hyun-Soo;Kim, Kyung-Soo;Shim, In-Sop
    • The Korean Journal of Physiology and Pharmacology
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    • v.15 no.6
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    • pp.333-338
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    • 2011
  • Black ginseng (BG) has been widely used as herbal treatment for improving physiological function. In order to investigate the neuroprotective action of this herbal medicine, we examined the influence of BG on the learning and memory of rats using the Morris water maze, and we studied the effects of BG on the central cholinergic system and neural nitric oxide synthesis in the hippocampus of rats with neuronal and cognitive impairment. After middle cerebral artery occlusion was applied for 2h, the rats were administered BG (100 or 400 $mgkg^{-1}$, p.o.) daily for 2 weeks, followed by training and performance of the Morris water maze test. The rats with ischemic insults showed impaired learning and memory on the tasks. Treatment with BG produced improvement in the escape latency to find the platform. Further, the BG groups showed a reduced loss of cholinergic immunoreactivity and nicotinamide adenine dinucleotide phosphate-diaphorase (NADPH-d)-positive neurons in the hippocampus compared to that of the ISC group. These results demonstrated that BG has a protective effect against ischemia-induced neuronal and cognitive impairment. Our results suggest that BG might be useful for the treatment of vascular dementia.