• Biomolecules & Therapeutics
• /
• v.6 no.1
• /
• pp.63-72
• /
• 1998

-4-Quinolone antibiotics (pefloxacin, ciprofloxacin, norfoxacin, ofloxacin and enoxacin) were tested for mutagenicity in Salmonella typhimurium TA98, TA100, TA1535, TA1537, TA1538 and TA102, for chromosomal aberrations in cultured Chinese hamster lung (CHL) cells, and for wing somatic mutations and recombinations (wing spot) in Drosophila. Five 4-quinolones did not show any mutagenicity in Salmonella typhimurium TA98, TA100, TA1535, TA1537 and TA1538. However, they were mutagenic inSalmonella typhimurium TA102 with and without metabolic activation in both plate incorporation method and preincubation method. Ciprofloxacin induced structural chromosome aberrations in CHL cells both with and without metabolic activation, and the frequencies were 6% and up to 28%, respectively. Pefloxacin showed equivocal evidence, however, norfloxacin, ofloxacin and enoxacin did not induce the structural chromosome aberrations both in the presence and absence of metabolic activation. In the wing spot assay in Drosophila, ofloxacin increased the frequency of small single spots significantly in a dose-dependent manner but there was no dose-dependent increase of single or twin spots in the others.

• KOREAN JOURNAL OF CROP SCIENCE
• /
• v.51 no.spc1
• /
• pp.277-282
• /
• 2006

The aim of this study was to develop the tartary buckwheat (Fagopyrum tataricum Gaertn.) sprouts and to clarify the biological and chemical characteristics of the sprouts. At 7 days after seeding, hypocotyls length and thickness, and root length of tartary buckwheat sprouts were 137 cm, 1.4 mm, and 12.6 cm, respectively. Fresh weight, dry weight, and moisture contents of an individual sprout at 7 days after seeding were 202 mg, 5.4 mg, and 95.3%, respectively. Protein content in tartary buckwheat sprouts was 23.0% which relatively higher than that of seeds, while lipid and ash contents were 3.5% and 5.3%. Among 7 minerals, the content of phosphorus showed the highest level (1,383.5 mg/100 g), while the contents of sodium and potassium were 1,197.5 mg/100 g and 1,106 mg/100 g, respectively. The contents of other minerals were Mg (795.5 mg/100 g), Ca (149 mg/100 g), Zn (16.4 mg/ 100 g), and Fe (14.7 mg/100 g). The rutin content of tatary buckwheat sprouts including root parts was the highest (5644.9 mg/100 g) at 7 days after seeding. The concentration of catechin derivatives in tartary buckwheat sprouts was high in order of catechin (59 mg/100 g), epicatechin gallate (47 mg/100 g), and epicatechin (14 mg/100 g).

• Proceedings of the KIEE Conference
• /
• 2011.07a
• /
• pp.222-223
• /
• 2011

본 논문은 인천지역 345kV 계통고장전류 저감을 위한 한류리액터 설치에 따른 362kV 50kA 차단기의 과도회복 전압 정격 초과 여부를 EMTP을 활용하여 검토하였다. 과도회복전압(TRV : Transient Recovery Voltage)은 크게 두가지, 최대전압(Vp)과 초기과도회복전압상승율(RRRV:Rate of Rise of Recovery Voltage)로 구분하며, 리액턴스 성분이 증가하며 RRRV가 상승하여 차단기가 고장전류을 차단시 절연파괴(열파괴)로 이어질 수 있다. IEC 62271-100 규정에는 RRRV를 정격차단전류의 100% 크기(T100%) 차단시 2kV/us이내로 규정하고 있으며 이 보다 작은 전류의 T90, T75 차단시의 규정치는 계산식에 의해 정해진다.

• Archives of Pharmacal Research
• /
• v.14 no.2
• /
• pp.109-113
• /
• 1991

Two types of aggressive behavior were produced by selective breeding in ICR mimce. NC900 line mice exhibited high level of species-typical, isolation-induced aggression, conversely, NC100 line mice exhibited little aggression. The present study tested the hypothesis that these differences involved brain monoamine systems. Comparisons of microdissected samples from various brain regions showed that NC100 line mice had significantly lower concentrations of dopamine. DOPAC and HVA in the nucleus accumbens (NAB) and caudate nucleus (NCU) than NC900 line. Homogenate binding studies demonstrated that NC100 mice had significantly increased density of $D_1$ dopamine receptor, but not $D_2$ dopamine receptor in the caudate nucleus. These results support the hypothesis that central dopamine pathways play an important role in modulating the genetically selected differences in aggressive behavior, and of which intensity differs from TEX>$D_1$\;and\;$D_2$ dopamine receptors.

• Preventive Nutrition and Food Science
• /
• v.22 no.2
• /
• pp.100-106
• /
• 2017

To elucidate new biological ingredients in cold-brew coffee extracted with cold water, crude polysaccharide (CCP-0) was isolated by ethanol precipitation, and its immune-stimulating activities were assayed. CCP-0 mainly comprised galactose (53.6%), mannose (15.7%), arabinose (11.9%), and uronic acid (12.4%), suggesting that it might exist as a mixture of galactomannan and arabinogalactan. CCP-0 significantly increased cell proliferation on both murine peritoneal macrophages and splenocytes in a dose dependent manner. CCP-0 also significantly augmented nitric oxide and reactive oxygen species production by murine peritoneal macrophages. In addition, macrophages stimulated by CCP-0 enhanced production of various cytokines such as tumor necrosis factor-${\alpha}$, interleukin (IL)-6, and IL-12. In an in vitro assay for intestinal immune-modulating activity, CCP-0 showed higher bone-marrow cell-proliferation activity through Peyer's patch cells at $100{\mu}g/mL$ than the negative control. These results suggest that CCP-0 may potentially enhance macrophage functions and the intestinal immune system.

• Proceedings of the Korean Society of Applied Pharmacology
• /
• 1998.11a
• /
• pp.147-147
• /
• 1998

The present study was designed to examine the effect of total ginseng saponin on CA secretion evoked by activation of nicotinic receptors from the isolated perfused rat adrenal glands. Total ginseng saponin given (100 $\mu\textrm{g}$/20 min) into an adrenal vein did fail to produce alteration of spontaneous CA release from the rat adrenal medulla. Acetylcholine (5.32 mM)- and DMPP (100 uM, a selective ncotinic receptor agonist)-evoked CA secretory responses were reduced markedly by the pretreatment with the total ginseng saponin at a rate of 100 $\mu\textrm{g}$/6.2 $m\ell$/20 min, respectively.

• Proceedings of the Korean Society of Grassland Science Conference
• /
• 1999.06a
• /
• pp.99.1-100
• /
• 1999

본 연구는 연맥 및 헤어리 베치를 사일리지로 이용하기 위하여 예건 및 젖산균 첨가에 따른 사일리지 품질에 미치는 영향을 구명코자 축산기술연구소 초지사료과에서 실시하였다. 젖산균 첨가량은 원물 100톤 기준으로 젖산균 1,135g에 물 100$\ell$ 혼합하여 24시간 배양하여 분무하였다. 연맥 및 헤어리 베치의 예취 직후 건물률이 각각 18.4%와 15.9%에서 3일 예건했을 경우 26.5%와 29.9%로 사일리지 조제에 좋은 조건이었다.(중략)

• Korean Journal of Organic Agriculture
• /
• v.12 no.4
• /
• pp.399-409
• /
• 2004

This study was conducted to investigate the effect of different concentrations of microbial products on growth of chinese cabbage and microorganisms in soil. Two different levels of microbial products, such as 50 times and 100 times diluted solutions of chitosan, wood vinegar and EM activity liquid, were treated for foliar application. the results were summarized as follows : Among foliar applications of microbial products, 100 times diluted solution of chitosan was effective on growth of chinese cabbage comparing to other levels of dilutions and untreated control plot. The number of microorganism in the soil tended to increase under the treatment of microbial products compared to control plot. Especially, the numbers of the bacteria and actinomycetes were estimated $73.67{\times}10^3$ CFU/g and $34.00{\times}10^3$ CFU/g, respectively, under the treatment of 100 times diluted solution of chitosan.

• Korean Journal of Organic Agriculture
• /
• v.12 no.4
• /
• pp.427-436
• /
• 2004

This study was conducted to investigate the effect of microbial product on microorganisms in soil and the growth of leaf lettuce. The test material were treated with chitosan, wood vinegar and EM activity liquid, and treatment concentration was 50 times solution and 100 times solution level with foliar application. The results were summarized as follows : Among foliar application of microorganisms treatments diluted by chitosan 100 times solution level was effective considering growth of leaf lettuce as compared other dilutions and control plot. Change of microorganism number in the soil for cultivation of chinese cabbages and leaf lettuce was increased with microorganism treatment plot as compared with control plot. Specially chitosan 100 times solution level showes the most significant effect.

• Proceedings of the Korean Society of Disaster Information Conference
• /
• 2023.11a
• /
• pp.351-352
• /
• 2023

동물용 고압산소치료 시 산소를 통한 가압은 이미 있는 공기를 제거하고 산소로 대치시키는데 효율성이 떨어져서 100%에 가까운 산소분압을 구현하는데 어려움이 있고, 그 방법도 표준화되지 않았다. 따라서 어떠한 방식의 산소가압이 신속하고 효율적으로 100%에 가까운 산소분압을 구현할 수 있는지에 대한 방안을 개발하고 표준화할 필요가 있다. 동물용 고압산소치료를 활용한 동물실험이나 동물의 치료 중 가압 단계에서 간헐적 환기 방법이 더 신속하게 100%에 가까운 산소 분압을 보이므로 향후 표준 지침 개발을 위한 중요한 기반 연구와 제안으로 활용 가능하다. 이는 재난 기반으로의 고압산소챔버의 활용을 위한 기초 자료가 될 것이다.