• Polymer(Korea)
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• v.34 no.4
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• pp.300-305
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• 2010

Zaltoprofen is a propionic acid derivative of non-steroidal anti-inflammatory drugs (NSAIDs) and has been widely used in the treatment of a number of arthritic conditions or lumbago. Zaltoprofen has low water solubility and low bioavailability, therefore great efforts have been devoted to enhance the extent of drug adsorption. In this study, zaltoprofen was formulated into a tablet to enhance the bioavailability and to achieve sustained-release using additives such as lactose monohydrate, carboxymethylcellulose (CMC), hydroxypropylmethylcellulose (HPMC). Fourier transform-infrared (FTIR) and differential scanning calorimeter (DSC) were employed to study the structure and crystallization of zaltoprofen in the tablet with various contents of additives. It was found that additives had interactions with zaltoprofen and inhibited the crystallization of zaltoprofen. Tablets containing low viscosity HPMC showed a higher release than those containing high viscosity HPMC. Also, as the amount of CMC increased zaltoprofen release increased.

• Journal of the Korea Convergence Society
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• v.12 no.12
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• pp.39-47
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• 2021

The construction of high-quality input features through effective segmentation is essential for increasing the sentence comprehension of a language model. Improving the quality of them directly affects the performance of the downstream task. This paper comparatively studies the segmentation that effectively reflects the linguistic characteristics of Korean regarding word and sentence classification. The segmentation types are defined in four categories: eojeol, morpheme, syllable and subchar, and pre-training is carried out using the RoBERTa model structure. By dividing tasks into a sentence group and a word group, we analyze the tendency within a group and the difference between the groups. By the model with subchar-level segmentation showing higher performance than other strategies by maximal NSMC: +0.62%, KorNLI: +2.38%, KorSTS: +2.41% in sentence classification, and the model with syllable-level showing higher performance at maximum NER: +0.7%, SRL: +0.61% in word classification, the experimental results confirm the effectiveness of those schemes.

• Journal of the Korea Society of Computer and Information
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• v.26 no.11
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• pp.1-9
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• 2021

3D-NAND flash memory provides high capacity per unit area by stacking 2D-NAND cells having a planar structure. However, due to the nature of the lamination process, there is a problem that the frequency of error occurrence may vary depending on each layer or physical cell location. This phenomenon becomes more pronounced as the number of write/erase(P/E) operations of the flash memory increases. Most flash-based storage devices such as SSDs use ECC for error correction. Since this method provides a fixed strength of data protection for all flash memory pages, it has limitations in 3D NAND flash memory, where the error rate varies depending on the physical location. Therefore, in this paper, pages and layers with different error rates are classified into clusters through the K-means machine learning algorithm, and differentiated data protection strength is applied to each cluster. We classify pages and layers based on the number of errors measured after endurance test, where the error rate varies significantly for each page and layer, and add parity data to stripes for areas vulnerable to errors to provides differentiate data protection strength. We show the possibility that this differentiated data protection policy can contribute to the improvement of reliability and lifespan of 3D NAND flash memory compared to the protection techniques using RAID-like or ECC alone.

• Journal of the Korean Geotechnical Society
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• v.37 no.7
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• pp.13-23
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• 2021

If roads, bridges, buildings, etc. are built on the ground with soft clay or organic soil, there may be a lot of problems in geotechnical engineering such as settlement and stability due to the large settlement and lack of bearing capacity. In extreme cases, it may appear due to shear failure or collapse of the constructed structure, so a ground improvement method is indispensable to increase the strength of the ground and to suppress settlement. In this study, the settlement according to each groundwater level condition was analyzed using the measurement results for the groundwater level conditions, one of the important factors in predicting the settlement in dredged and reclaimed ground, and the groundwater level conditions applied to the settlement analysis were proposed by comparing it with settlement generated 5 years after construction. As a result of the analysis, it is judged that it is reasonable to apply the measured groundwater level during construction and the low water ordinary neap tide (L.W.O.N.T) during load application for the groundwater level in the settlement analysis. In addition, in the case of the dredged and reclaimed ground, it is estimated that the water pressure acting on the clay layer is nonlinear, as the result of the observations of the head of water at the observation points above and below the in-situ clay layer were different.

• Genes and Genomics
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• v.40 no.11
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• pp.1249-1258
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• 2018

The Jeju horse is an indigenous Korean horse breed that is currently registered with the Food and Agriculture Organization of the United Nations. However, there is severe lack of genomic studies on Jeju horse. This study was conducted to investigate genetic characteristics of horses including Jeju horse, Thoroughbred and Jeju crossbred (Jeju${\times}$Thoroughbred) populations. We compared the genomes of three horse populations using the Equine SNP70 Beadchip array. Short-range Linkage disequilibrium was the highest in Thoroughbred, whereas $r^2$ values were lowest in Jeju horse. Expected heterozygosity was the highest in Jeju crossbred (0.351), followed by the Thoroughbred (0.337) and Jeju horse (0.311). The level of inbreeding was slightly higher in Thoroughbred (-0.009) than in Jeju crossbred (-0.035) and Jeju horse (-0.038). $F_{ST}$ value was the highest between Jeju horse and Thoroughbred (0.113), whereas Jeju crossbred and Thoroughbred showed the lowest value (0.031). The genetic relationship was further assessed by principal component analysis, suggesting that Jeju crossbred is more genetically similar to Thoroughbred than Jeju horse population. Additionally, we detected potential selection signatures, for example, in loci located on LCORL/NCAPG and PROP1 genes that are known to influence body. Genome-wide analyses of the three horse populations showed that all the breeds had somewhat a low level of inbreeding within each population. In the population structure analysis, we found that Jeju crossbred was genetically closer to Thoroughbred than Jeju horse. Furthermore, we identified several signatures of selection which might be associated with traits of interest. To our current knowledge, this study is the first genomic research, analyzing genetic relationships of Jeju horse, Thoroughbred and Jeju crossbred.

• Cross-Cultural Studies
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• v.46
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• pp.173-197
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• 2017

The present work aims to analyze the concept of space in $Jes{\acute{u}}s$ $Fern{\acute{a}}ndez$ Santos' work Los bravos. Throughout its pages, one can observe the multidimensional possibilities of space in literature. Throughout time, the concept of literary space has developed and it has been modified constantly in order to meet the needs required for the evolution of narratology. In the past, Aristotle stated that space is the place where characters and physical objects happen to exist. This remained almost unchanged until the Renaissance. In the $19^{th}$ century, space stopped being considered just a mere scene where the action takes place as it was given more importance by romantic authors in their works. Realism intensified the spaces as the interior of the house. In fact, the descriptions of space became more important. In this article, I focus on the various meanings of space in the novel Los bravos. First, I analyze the dichotomy between real and ideal spaces, and continue with the cathartic dimension of the fictional space. Then, I present and analyze the opposition between urban and rustic spaces in this novel, and, finally, I show the confrontation between the spaces of men and women. Through this analysis, we can observe that characters have a space where they feel more comfortable and how, occasionally, they leave their "usual space of action" to reach their "ideal place". Women want to stay in their kitchen to chat with each other, while men prefer to leave the house to visit a cafe with their colleagues. The door and the window divide the border of the worlds of men and women. However, that line is not only dividing the structure of the house, but it is also of a psychological house.

• Journal of the Korean Society of Radiology
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• v.12 no.6
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• pp.793-799
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• 2018

As interest in artificial intelligence has increased, artificial intelligence has been actively studied in the medical field. In Korea, artificial intelligence has been applied to medical imaging devices such as X-ray imaging, Computer Tomography and Magnetic Resonance Imaging and artificial intelligence capable of acquiring radiation images of patients without radiologists in the future Medical devices are expected to be invented. This study was an initial study on the automation of patient positioning in X - ray imaging. We used x-ray equipment and human phantoms to evaluate the positioning. The program used Visual Studio 2010 MFC and the image was in the size $1450{\times}1814$. The pixel values were converted to contrasts with values of 0 to 255 that can be visually recognized and output to the monitor. We developed a procedure algorithm program that predicts the angle of the output image through three pixel coordinate values and induces the patient to perform correct positioning according to the voice guidance according to the angle. In the next study, we will study the artificial intelligence to grasp the structure itself and calculate the angle, rather than conveying the reference of coordinates to artificial intelligence. In the future, it is expected that it will be helpful in the study of artificial intelligence from shooting to positioning through the automation of positioning.

• Journal of the Korean earth science society
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• v.40 no.3
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• pp.203-211
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• 2019

The two key factors controlling the atmospheric general circulation are the equator-to-pole temperature difference and the Coriolis force driven by Earth's rotation. Although the former's role has been extensively examined, little has been reported about the latter's effect. To better understand the atmospheric general circulation, this study investigates the responses of Hadley Cell (HC) and westerly jet to the rotation faster or slower than the present Earth's rotation rate. It turns out that the HC edge and jet position tend to move equatorward and become weaker with increasing rotation rate. In most cases, the HC edge is quasi-linearly related with the jet position except for the extremely slow or fast rotating cases. The HC edge is more inversely proportional to the root of rotation rate than the rotation rate in the range of 1/8 to 8 times of the current Earth's rotation rate. However, such a relationship does not appear in the relationship between HC strength and jet intensity. This result highlights that while the latitudinal structure of atmospheric general circulation can be, to some extent, scaled with the Earth's rotation rate, overall intensity cannot be simply explained by the Earth's rotation rate.

• Journal of Korean Dental Science
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• v.11 no.2
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• pp.71-81
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• 2018

Purpose: The purpose of this study was to investigate the corrosion behaviors of dental implant alloy after microsized surface modification in electrolytes containing Mn ion. Materials and Methods: $Mn-TiO_2$ coatings were prepared on the Ti-6Al-4V alloy for dental implants using a plasma electrolytic oxidation (PEO) method carried out in electrolytes containing different concentrations of Mn, namely, 0%, 5%, and 20%. Potentiodynamic method was employed to examine the corrosion behaviors, and the alternatingcurrent (AC) impedance behaviors were examined in 0.9% NaCl solution at $36.5^{\circ}C{\pm}1.0^{\circ}C$ using a potentiostat and an electrochemical impedance spectroscope. The potentiodynamic test was performed with a scanning rate of $1.667mV\;s^{-1}$ from -1,500 to 2,000 mV. A frequency range of $10^{-1}$ to $10^5Hz$ was used for the electrochemical impedance spectroscopy (EIS) measurements. The amplitude of the AC signal was 10 mV, and 5 points per decade were used. The morphology and structure of the samples were examined using field-emission scanning electron microscopy and thin-film X-ray diffraction. The elemental analysis was performed using energy-dispersive X-ray spectroscopy. Result: The PEO-treated surface exhibited an irregular pore shape, and the pore size and number of the pores increased with an increase in the Mn concentration. For the PEO-treated surface, a higher corrosion current density ($I_{corr}$) and a lower corrosion potential ($E_{corr}$) was obtained as compared to that of the bulk surface. However, the current density in the passive regions ($I_{pass}$) was found to be more stable for the PEO-treated surface than that of the bulk surface. As the Mn concentration increased, the capacitance values of the outer porous layer and the barrier layer decreased, and the polarization resistance of the barrier layers increased. In the case of the Mn/Ca-P coatings, the corroded surface was found to be covered with corrosion products. Conclusion: It is confirmed that corrosion resistance and polarization resistance of PEO-treated alloy increased as Mn content increased, and PEO-treated surface showed lower current density in the passive region.

• Korean Journal of Construction Engineering and Management
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• v.22 no.5
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• pp.73-85
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• 2021

This study proposes an efficient management direction for Korean construction accident cases through a deep learning-based text data classification model. A deep learning model was developed, which categorizes five categories of construction accidents: fall, electric shock, flying object, collapse, and narrowness, which are representative accident types of KOSHA. After initial model tests, the classification accuracy of fall disasters was relatively high, while other types were classified as fall disasters. Through these results, it was analyzed that 1) specific accident-causing behavior, 2) similar sentence structure, and 3) complex accidents corresponding to multiple types affect the results. Two accuracy improvement experiments were then conducted: 1) reclassification, 2) elimination. As a result, the classification performance improved with 185.7% when eliminating complex accidents. Through this, the multicollinearity of complex accidents, including the contents of multiple accident types, was resolved. In conclusion, this study suggests the necessity to independently manage complex accidents while preparing a system to describe the situation of future accidents in detail.