• Child Health Nursing Research
• /
• v.7 no.4
• /
• pp.421-433
• /
• 2001

The purpose of this phenomenological study was to understand the lived experience of mothers of children with muscular dystrophy. The participants were 11 mothers recruited by snowball sampling, who agreed with the objectives of the research and could verbally communicate with the researcher and who lived with their sons who had muscular dystrophy. Data collection was done through in-depth interviews with participants in their own homes. Each interview took 50 to 120 minutes. All of the interviews were audiotaped and then transcribed. Data were analyzed using Colaizzi's (1978) method of phenomenology. From the transcripts 109 significant sentences and phrases were selected and 13 clusters of themes were categorized from 67 significant statements. These results were integrated into the essential structure of the lived experience of mothers of children with muscular dystrophy. 1. Anxious and relying on chance due to indefinite diagnosis. 2. Only able to cry with shock because of son's fatal disease. 3. Seeing the future as dismal and feeling resentment that this disease in transmitted through the mother. 4. Feeling caught between a husband who is distancing himself from his family and the family which is disintegrating. 5. Feeling like a sinner for transmission of genetic disease(Feeling guilt for conceiving a son with a genetically transmitted fatal disease). 6. Empathizing with other suffers of muscular dystropy and their parents in their grief and helping to dissipate their heavy feelings. 7. Deciding to sacrifice self as a way of taking responsibility for giving birth to a handi-capped son. 8. Losing hope (feeling despair) as son's condition deteriorates in spite of all attempts to help him. 9. Wishing to die with son who becomes progressively immobile. 10. Accumulating Han*(한, 恨), because of rising Hwa(화, anger), and becoming sick both mentally and physically. 11. Seeing events as destiny and finding self-control through faith. 12. Finally, giving up sacrificing self for son and becoming concerned(involved) with other children in the family. 13. Feeling fear at son's impending death. This is the first research on the experience of Korean mothers of children with muscular dystrophy. In applying the phenomenology research method, this study not only helps health professionals understand the experience of these mothers in the Korean patriarchal social system, but the researcher, as a nurse, can share their agony and grief through identification of their inner world through in-depth personal interviews. The results obtained in this study will not only help in the development of family nursing practice for families with genetically transmitted diseases but also prepare basic data for family nursing practice in the Korean sociocultural context.

• Korean Management Science Review
• /
• v.28 no.3
• /
• pp.1-13
• /
• 2011

Hub-and-spoke transportation network is a powerful and useful network structure that takes full advantage of economies of scale on routes between hubs. In recent studies, the network structure is extended to hybrid hub-andspoke that allows direct transportation between spokes. In this study, we considered more extended network structure which is called hybrid multiple hub-and-spoke that has multiple hubs and allows direct transportation between spokes. We developed a mathematical optimization model for automotive service parts transportation planning under hybrid multiple hub-and-spoke network structure. The model suggests a long-term transportation route planning and a short-term vehicle assignment planning. The model is verified by simulation and validated in real world application to Hyundai Mobis automotive service parts transportation planning. From the simulation result, the model reduced the transportation cost about 24.7%, the total distance about 6.8% and the CO2 emissions about 8.8%. In real world application for 6 months from July to December 2010, the model reduced the transportation cost about 9.1% by changing the long-term transportation route without daily vehicle assignment planning.

• BMB Reports
• /
• v.40 no.2
• /
• pp.261-269
• /
• 2007

The structure and dynamics of a 37-residue antimicrobial peptide gaegurin 4 (GGN4) isolated from the skin of the native Korean frog, Rana rugosa, was determined in SDS micelles by NMR spectroscopy. The solution structure of the peptide in SDS micelles was determined from 352 NOE-derived distance constraints and 22 backbone torsion angle constraints. Dynamic properties for the amide backbone were characterized by $^1H-^{15}N $heteronuclear NOE experiments. The structural study revealed two amphipathic helices spanning residues 2-10 and 16-32 and that the helices were connected by a flexible loop. An intraresidue disulfide bridge was formed between residues Cys31 and Cys37 near the C-terminus. The loop region (11-15) connecting the two helices are were slightly more flexible than these helices themselves. From the fact that since there is no contact NOEs between two helices, it is implied that the GGN4 peptide shows an independent motion of both helices which has an angle of about $ 60^{\circ}-120^{\circ}$ from each other.

• Proceedings of the Korean Society of Dyers and Finishers Conference
• /
• 2011.03a
• /
• pp.63-63
• /
• 2011

The donor-${\pi}$-acceptor (D-${\pi}$-A) chromophoric dye system has received great attention in variety fields such as electroluminescent materials, sensors and optoelectronic devices. There are many research activities focused on the development for abovementioned application materials with the high-performance properties. In the previous work, we are reported that novel D-${\pi}$-A dye, 2-[4-(9H-carbazol-9-yl)benzylidene]-2,3-dihydroinden-1-one, is successfully attained and exhibited a positive fluorescence solvatochromism. In this work, the molecular structure and packing geometry of 2-[4-(9H-carbazol-9-yl)benzylidene]-2,3-dihydroinden-1-one was discussed by their conformational structure. Their single yellow prism crystal having approximate dimensions of $0.30{\times}0.10{\times}0.10$ mm was carried out with a Rigaku RAXIS RAPID imaging plate area detector with graphite monochromated $CuK_{\alpha}$ radiation. Their crystal structure were solved by using the CrystalStructure crystallographic software package.

• Journal of the Korean Magnetic Resonance Society
• /
• v.11 no.1
• /
• pp.24-29
• /
• 2007

[ ${\beta}ig-h3$ ] is an extracellular matrix protein that mediates cell adhesion through interaction with integrins. The 18 residue YH motifs within each fas-1 domain are known to be responsible for the interaction with the ${\alpha}_v{\beta}_5$ integrin, and the synthetic YH motif peptides are known to inhibit endothelial tube formation and reduces the number of blood vessels, and so expected to be an effective inhibitor of angiogenesis. In this study, we solved the 3D structure of the 18 residue YH motif peptide (EALRDLLNNHILKSAMCA; D2 peptide) within the second fas-1 domain of ${\beta}ig-h3$ using NMR. The Peptide has ${\alpha}-helix$ structure at the C terminal region but the N terminal region is flexible. The present structural information may be helpful for developing more effective peptide drug candidate for the treatment of diseases dependent on angiogenesis.

• Transactions of the Korean Society of Mechanical Engineers A
• /
• v.24 no.6 s.177
• /
• pp.1371-1378
• /
• 2000

To reduce backpressure for improving engine power in exhaust system, a large difference of pressure is required, but this is in conflict with the requirement for reducing exhaust noise that needs a small pressure difference. In this paper, the controllable muffler designed by simplifying the structure of the exhaust system has a low backpressure and a proper sound specification to the rotation of engine. The exhaust system in conventional studies has been designed to have maximum noise reduction over the whole driving domain, but due to its complex structure this led to increased backpressure. If the muffler is designed according to the driving frequency, which is a dominant noise component in stationary driving speed, the backpressure is reduced due to the simplified structure of the muffler. Furthermore, a multi-mode muffler able to change structure with varied driving speed was designed.

• Transactions of the Korean Society of Mechanical Engineers A
• /
• v.27 no.8
• /
• pp.1353-1362
• /
• 2003

This paper considers a simultaneous optimization problem of structure and control systems. The problem is generally formulated as a non-convex optimization problem for the design parameters of mechanical structure and controller. Therefore, it is not easy to obtain the global solutions for practical problems. In this paper, we parameterize all design parameters of the mechanical structure such that the parameters work in the control system as decentralized static output feedback gains. Using this parameterization, we have formulated a simultaneous optimization problem in which the design specification is defined by the Η$_2$and Η$\_$$\infty$/ norms of the closed loop transfer function. So as to lead to a convex problem we approximate the nonlinear terms of design parameters to the linear terms. Then, we propose a convex optimization method that is based on linear matrix inequality (LMI). Using this method, we can surely obtain suboptimal solution for the design specification. A numerical example is given to illustrate the effectiveness of the proposed method.

• Proceedings of the Korean Vacuum Society Conference
• /
• 2010.08a
• /
• pp.164-164
• /
• 2010

The impurity doped ZnO has been extensively studied because of its optoelectric properties. GIZO (Ga-In-Zn-O) amorphous oxide semiconductors has been widely used as transparent flexible semiconductor material. Recently, various amorphous transparent semiconductors such as IZO (In-Zn-O), GIZO, and HIZO (Hf-In-Zn-O) were developed. In this work, we examined the local structures of IZO, GIZO, and HIZO. The local coordination structure was investigated by the extended X-ray absorption fine structure. The IZO, GIZO and HIZO thin films ware deposited on the glass substrate with thickness of 400nm by the radio frequency sputtering method. The targets were prepared by the mixture of $In_2O_3$, ZnO and $HfO_2$ powders. The percent ratio of In:Zn in IZO, Ga:In:Zn in GIZO and Hf:In:Zn in HIZO was 45:55, 33:33:33 and 10:35:55, respectively. In this work, we found that IZO, GIZO and HIZO are all amorphous and have a similar local structure. Also, we obtained the bond distances of $d_{Ga-O}=1.85\;{\AA}$, $d_{Zn-O}=1.98\;{\AA}$, $d_{Hf-O}=2.08\;{\AA}$, $d_{In-O}=2.13\;{\AA}$.

• 한국신재생에너지학회:학술대회논문집
• /
• 2008.10a
• /
• pp.131-133
• /
• 2008

A serious problem of the 21st century is the supply of energy resources. Reserves of fossil fuels are facing depletion: renewable energy resources must be developed in this era. Dye sensitized solar cell (DSC) has been very economical and easy method to convert solar energy to electricity. Recently a novel tandem cell structure is proposed to improve photocurrent of DSC. To fabricated a tandem cell, the mesh structure of counter electrode is essential for the improvement in transmittance. In this study, we conducted the experiment to get the characteristic of DSC with mesh counter electrode. Under the standard test condition (AM 1.5, 100mW/$cm^2$), we obtained the maximum efficiency of 3.41% and the transmittance of 72% in the DSC with mesh counter electrode.

• Journal of Magnetics
• /
• v.15 no.1
• /
• pp.12-16
• /
• 2010

Combined study of in-situ stress measurements and atomic force microscopy (AFM) revealed drastic stress relaxation in the CoCrPt and PS(styrene)-PVP(vinyl pyridine) polymer hybrid structure that was closely related to the growth structure of the film. We have observed not only no large initial growth stress at the initial stages of film growth but also twice smaller stress in magnitude with opposite sign in the CoCrPt/PS-PVP/Si sample. The microstructural studies using AFM at the various film growth stages revealed that the film growth structure plays an important role in the stress relaxation mechanism of CoCrPt films on a corrugated polymer surface.