• Proceedings of the Materials Research Society of Korea Conference
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• 2009.05a
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• pp.24.2-24.2
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• 2009

Nanostuctures such as nanodot and nanowire have been extensively studied as building blocks for nanoscale devices. However, the direct growth of the nanostuctures at the desired position is one of the most important requirements for realization of the practical devices with high integrity. Self-assembled nanotemplate is one of viable methods to produce highly-ordered nanostructures because it exhibits the highly ordered nanometer-sized pattern without resorting to lithography techniques. And selective epitaxial growth (SEG) can be a proper method for nanostructure fabrication because selective growth on the patterned openings obtained from nanotemplate can be a proper direction to achieve high level of control and reproducibility of nanostructucture fabrication. Especially, SiGe has led to the development of semiconductor devices in which the band structure is varied by the composition and strain distribution, and nanostructures of SiGe has represented new class of devices such nanowire metal-oxide-semiconductor field-effect transistors and photovoltaics. So, in this study, various shaped SiGe nanostructures were selectively grown on Si substrate through ultrahigh vacuum chemical vapor deposition (UHV-CVD) of SiGe on the hexagonally arranged Si openings obtained using nanotemplates. We adopted two types of nanotemplates in this study; anodic aluminum oxide (AAO) and diblock copolymer of PS-b-PMMA. Well ordered and various shaped nanostructure of SiGe, nanodots and nanowire, were fabricated on Si openings by combining SEG of SiGe to self-assembled nanotemplates. Nanostructure fabrication method adopted in this study will open up the easy way to produce the integrated nanoelectronic device arrays using the well ordered nano-building blocks obtained from the combination of SEG and self-assembled nanotemplates.

• Macromolecular Research
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• v.13 no.4
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• pp.285-292
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• 2005

We developed alginate beads loaded with transforming growth $factor-{\beta}_{1}(TGF-{\beta}_{1})$ to examine the possible application of the scaffold and cytokine carrier in tissue engineering. In this study, bone marrow stromal cells (BMSCs) and $TGF{\beta}_{1}$ were uniformly encapsulated in the alginate beads and then cultured in vitro. The cell morphology and shape of the alginate beads were observed using inverted microscope, scanning electron microscope (SEM), histological staining and RT-PCR to confirm chondrogenic differentiation. The amount of the $TGF{\beta}_{1}$ released from the $TGF-{\beta}_{1}$ loaded alginate beads was analyzed for 28 days in vitro in a phosphate buffered saline (pH 7.4) at $37^{\circ}C$. We observed the release profile of $TGF-{\beta}_{1}$ from $TGF-{\beta}_{1}$ loaded alginate beads with a sustained release pattern for 35 days. Microscopic observation showed the open cell pore structure and abundant cells with a round morphology in the alginate beads. In addition, histology and RT-PCR results revealed the evidence of chondrogenic differentiation in the beads. In conclusion, these results confirmed that $TGF-{\beta}_{1}$ loaded alginate beads provide excellent conditions for chondrogenic differentiation.

• Journal of Ginseng Research
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• v.41 no.1
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• pp.96-102
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• 2017

Background: Korean ginseng, Panax ginseng Meyer, has been used as a traditional oriental medicine to treat illness and promote health for several thousand years. Ginsenosides are the main constituents for the pharmacological effects of P. ginseng. Since several ginsenosides, including ginsenoside (G)-Rg3 and G-Rp1, have reported antiplatelet activity, here we investigate the ability of G-Rp4 to modulate adenosine diphosphate (ADP)-induced platelet aggregation. The ginsenoside Rp4, a similar chemical structure of G-Rp1, was prepared from G-Rg1 by chemical modification. Methods: To examine the effects of G-Rp4 on platelet activation, we performed several experiments, including antiplatelet ability, the modulation of intracellular calcium concentration, and P-selectin expression. In addition, we examined the activation of integrin ${\alpha}IIb{\beta}_3$ and the phosphorylation of signaling molecules using fibrinogen binding assay and immunoblotting in rat washed platelets. Results: G-Rp4 inhibited ADP-induced platelet aggregation in a dose-dependent manner. We found that G-Rp4 decreased calcium mobilization and P-selectin expression in ADP-activated platelets. Moreover, fibrinogen binding to integrin ${\alpha}IIb{\beta}_3$ by ADP was attenuated in G-Rp4-treated platelets. G-Rp4 significantly attenuated phosphorylation of extracellular signal-regulated protein kinases 1 and 2, p38, and c-Jun N-terminal kinase, as well as protein kinase B, phosphatidylinositol 3-kinase, and phospholipase C-${\gamma}$ phosphorylations. Conclusion: G-Rp4 significantly inhibited ADP-induced platelet aggregation and this is mediated via modulating the intracellular signaling molecules. These results indicate that G-Rp4 could be a potential candidate as a therapeutic agent against platelet-related cardiovascular diseases.

• Korean Journal of Food Science and Technology
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• v.31 no.6
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• pp.1410-1414
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• 1999

The granular size and shape of durian seed starch were $2.0-10.0\;{\mu}m$ and oval and polygonal. Amylose contents of durian seed, corn, sweet potato and potato starch were 28.3%, 27.5%, 20.3% and 21.7%, respectively. Blue value of durian seed (0.370) higher than that of corn (0.368), sweet potato (0.332), and potato starch (0.338). Alkali numbers of durian seed, corn, sweet potato and potato starch were 7.39, 9.02, 7.08 and 5.43, respectively. Swelling power of durian seed starch was similar to that of sweet potato starch. X-ray diffraction patterns of durian seed starch showed an A-type crystalline structure. According to pasting properties by Rapid Visco-Analyzer, the gelatinization temperature of durian seed starch $(76.6^{circ}C)$ was higher than that of corn $(73.0^{circ}C)$, sweet potato $(72.3^{circ}C)$ and potato starch $(70.2^{circ}C)$. The breakdown of durian seed starch were lower than that of corn, sweet potato and potato starch.

• Membrane Journal
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• v.21 no.4
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• pp.321-328
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• 2011

$PrBa_{0.9}Sr_{0.1}Co_2O_{5+{\delta}}$ oxide was synthesized by soild state reaction method. Dense ceramic membrane was prepared using as-prepared powder by pressing and sintering at $1250^{\circ}C$. XRD result of membrane showed double perovskite structure. Leakage and oxygen permeation test were conducted on the membrane sealed by pyrex ring as a sealing material. Oxygen permeation was measured in the temperature range from 850 to $950^{\circ}C$. The oxygen flux of $PrBa_{0.9}Sr_{0.1}Co_2O_{5+{\delta}}$ membrane was increased with the temperature from 0.15 to $0.32mL/cm^2{\cdot}min$.

• Journal of the Korean Geographical Society
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• v.46 no.2
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• pp.115-133
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• 2011

Yamada's mountain ordering is to be said as an upward system, because the area and volume of the mountains become the larger as more than two lower order mountains constitute the higher order mountain. However, his mountain ordering shows some limitations to totally understand the mountain systems and to systematically manage the various kinds of mountainous informations. Because the independent third, fourth and so on, as well as the second lower order mountains are included in the higher order mountain. In order to solve the problem above, the downward system is suggested as the alternative of his upward system. The downward system means that the higher order mountain is classified into the second lower order mountains, and the second lower order mountain is classified into the third lower order mountains and finally the 2nd order mountain classified into the 1st order mountains. The method to classify a certain mountain systematically into all mountainous elements and the new nomenclature to be used for the classified elements are developed, using the downward system above. And the structure of database could be also suggested for the integrated and systematic management of mountain informations.

• Research in Community and Public Health Nursing
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• v.12 no.1
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• pp.32-38
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• 2001

This study focused on the understanding the life of the elderly in the institution by phenomenological method. The participants were seven. who were 4 men and 3 women living in the elderly institution in Taegu. The data were collected through the indepth interviews and participant observation from June 20. 1999 to January 10. 2000 and analyzed by phenomenological analytic method by Giorgi. The structure of the meaning were as follows: Unhappy life: irresponsibility. self-centered thought. hardness. Irresistible life: misfortune. unhealthiness. Reading their son's intention. Bitter life: unfair treatment from their sons and daughters, betrayed feeling for their being thrown away. Outside oriented life: a fear of others' attention, wrong information about institutionalized life, maladjustment. Self-consolation life: comfortableness, convenience, economic merit of low cost. Dissatisfied life: discomfort from communal living. unkindness of the institution staffs, depreciated tendency to the elder people, irrational social security system. economic distress, physical pain, restrained feeling. Tenacity to their sons and daughters longingness for their sons and daughters, regretableness, waiting, Regretable life: remorse for their past life. agony, guilty, loneliness, grief, self-abandonment, self-depreciation, other residents' death in common. Inharmonious life with other residents complaint, conflict, ignorance, selfishness. Yearning life for opposite sex: sexual interest. Preparing for their life: control over their body and mind, consideration for others. A life with hope: blessing death, forever healthfulness, affiliation to their family. From the results of this study an education and consultation should be done as soon as possible to remove the negative recognition of the institutional life to the facility residents. the family and the future consumers of elderly institution. To minimize the maladjustment to facility life of residents, a new program and interventions for the new comer's are needed. The thesis with above results will widen the understandings of institutional residents and an important guidance for a better nursing care in elderly institutions of korea.

• The Korean Journal of Ecology
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• v.24 no.4
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• pp.233-237
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• 2001

Changes of the oribatid mite species composition during the litter decomposition was investigated in the north-facing and south-facing slopes with different lower vegetation (annual herbaceous plants in north and perennial Sasa in south) in the altitude 1,000 m of Mt. Jumbong, a nature reserve area in Korea, from August 1994 to September 1995. Total 58 species of oribatid mites were collected. The values of O1son's negative exponential index (k) were -0.56 in the south-facing slope and -0.49 in the north-facing slope, but there was no significant difference between them. The decomposition rate of litter increased rapidly until Oct. 1994, and decreased thereafter. Intensive settlement of the forest litter by oribatid mites was recorded in the autumn periods and it decreased in the next spring and summer. Species diversity index (H'), and species evenness (J') ranged from 1.74 to 2.69, and from 0.57 to 0.93, respectively, and the values were lowest in spring. In the successive periods of growing season, there followed great changes in the structure of species dominance. Heminothrus minor was one of the most dominant species in autumn in the first year when litter were placed, but was never recovered next seasons. In contrast, Platynothrus yamasakii was also dominant in the first autumn, then decreased very low in numbers in next spring and summer, but regained its number in autumn. On the other hand, an increase of the number during these periods was observed by Epidamaeus sp.2. Ceratopia bipilis and Epidamaeus sp.1 were abundant both in the north-and south-facing slopes. Trichogalumna nipponica was only found in the south-facing slope, and Nanhermannia elegantula was only found in the north-facing slope.

• Proceedings of the Korean Institute Of Construction Engineering and Management
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• 2007.11a
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• pp.234-238
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• 2007

Since the plant industry is a total business, it has great impact on the related industries and generates high value. However, in order to have a competitive engineering skills and capabilities, the plant industry requires long-term investment and a continuous strategic planning at the consortium level or national level. Also, a system needs to be established to share the information of the plant industry's overseas orders awarded and success factors. Thus, this study has conducted a survey and case study of the plant construction in foreign countries. Statistical analysis was performed and a basic data structure was built as a means of improving the future technological capabilities of the plant industry.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.28 no.11
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• pp.865-871
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• 2017

In this paper, a gelatin layer was formed on the surface of the twisted fiber-optic couplers fabricated by hydrofluoric acid, which can be used to measure relative humidity. The proposed method of sensors has advantage of low cost compared with the sensors based on the conventional electronic devices and takes beneficial characteristics of optical fibers and light. The fiber-optic sensors presented in this study show a measurement from about 40% to 85% relative humidity, and the experimental results agree well with the calculated results. Based on the design presented in this paper, the structure will enable promising applications in the detecting humidity and various hazardous gases.