• 제목/요약/키워드: SND

검색결과 73건 처리시간 0.023초

Aspergillus nidulans에서 GAL4 유사 전사인자를 암호화하는 gtfA 유전자의 분리 및 분석 (Isolation and Characterization of the gtfA Gene Encoding GAL4-Like Transcription Factor in Aspergillus nidulans)

  • 박재신;한동민
    • 미생물학회지
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    • 제49권1호
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    • pp.8-16
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    • 2013
  • sndA 유전자(AN3911) 하위에 위치하고 있는 GAL4형 전사인자를 암호화하는 유전자(AN3912)에 대해 분석하였다. 이 전사인자는 Zn(II)2Cys6 binuclear cluster DNA-binding domain 과 전사활성부위를 모두 가지고 있는 전형적 진균 특이 전사인자로서 해당 유전자는 gtfA (gal4 type transcription factor)라 명명되었다. 이 유전자의 ORF는 762개의 아미노산으로 구성되어 있고 3개의 intron이 그 안에 존재하였다. gtfA 유전자의 결실돌연변이는 무성포자생성이 감소하고 대신 유성생식기관이 증가하는 형질을 보여주었다. 과다발현균주는 높은 포도당 농도가 주어지면 유성생식이 늦어지는 형질을 나타내었다. gtfA 유전자는 영양생장 후반부와 유성분화 초기단계에서 높은 발현량을 보이고 전생활사를 통해 비교적 일정하게 발현되었다. gtfA의 전사는 일부 유성(NsdD, VeA) 및 무성(FluG, FadA, SfaD) 분화 조절자들에 의해 크게 영향을 받지 않았다. 반면 GtfA는 nsdC 유전자의 발현을 억제하는 것으로 나타났다. 종합하여 볼 때, GtfA는 분화 결정시기에 nsdC의 발현을 억제함으로써 유성분화보다는 무성분화로 유도되도록 조절 할 것으로 추정된다.

Schiff Base Co(II) 착물이 변성된 유리질 탄소전극에서 산소 환원의 전기촉매 효과 (Electrocatalytic Effect of Dioxygen Reduction at Glassy Carbon Electrode Modified with Schiff Base Co(II) Complexes)

  • 성정섭;채희남;최용국
    • 분석과학
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    • 제11권6호
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    • pp.460-468
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    • 1998
  • $SOPDH_2$, $SNDH_2$, $EBNH_2$, $PBNH_2$ Schiff base 리간드와 이들의 [$Co(II)(SND)(H_2O)_2$], [$Co(II)(SOPD)(H_2O)_2$], [$Co(II)(EBN)(H_2O)$], [$Co(II)(PBN)(H_2O)$] 착물들을 합성하였다. Co(II) 착물들에서 Schiff base 리간드와 Co(II)의 몰 결합 비는 1:1로 주어졌으며 6배위 결합을 합성하였다. Co(II) 착물이 수식된 유리질 탄소전극을 사용하여 1 M KOH 수용액에서 산소 환원 반응을 순환 전압전류법으로 알아보았다. Schiff base Co(II) 착물이 수식된 전극에서의 산소의 환원 전류는 알몸 유리질 탄소전극에서 보다 더 증가하였고 환원 전위는 양전위 방향으로 더 이동하였다. 산소 환원 반응에 관여한 전자수와 교환 속도 상수 값은 순환 전압전류 곡선으로부터 구하였다. 산소 환원 반응경로는 최종 생성물이 $H_2O_2$로 가는 $2e^-$ 전이 반응을 나타내었으며 촉매가 수식된 전극에서의 교환 속도 상수는 알몸전극의 값에 비해 약 2~10배 정도 증가하였다.

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비수용매에서 산소 첨가된 네자리 Schiff Base Cobalt(Ⅲ) 활성 촉매들에 의한 2,6-di-tert-butylphenol의 선택 산화와 전기화학적 성질 (Selective Oxidation of 2,6-di-tert-butylphenol and Electrochemical Properties by Oxygen Adducted Tetradentate Schiff Base Cobalt (Ⅲ) Activated Catalysts in Aprotic Solvents)

  • 조기형;최용국;함희석;김상복;서성섭
    • 대한화학회지
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    • 제34권6호
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    • pp.569-581
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    • 1990
  • DMF 용매에서 산소 첨가된 네자리 Schiff base cobalt(III)의 균일 촉매에 의하여 2,6-di-tert-butylphenol의 산화 주생성물인 2,6-ditert-butylbenzoquinone (BQ)일 때에는 O$_2$/Co몰 결합비가 1:1인 superoxo cobalt(III) 착물 곧 [Co(III)(Schiff base)(L)]$O_2$ (Schiff base; SED, SOPD and o-BSDT, L; DMF and Py)들의 활성촉매에 의하여 생긴다. 또, 산화생성물인 3,3',5,5'-tetra-tert-butyldiphenoquinone (DPQ)은 $O_2$/Co의 몰비가 1:2인 $\mu$-peroxo cobalt(III) 착물인 [Co(III)(SND)(L)]$_2$O$_2$ (L; DMF 및 Py)의 활성촉매에 의하여 생성된다. 이들 균일 활성촉매인 superoxo 및 $\mu$-peroxo cobalt(III) 착물들의 확인은 DMF나 DMSO 용매에서는 어렵다. 그러나 pyridine 용매에서는 산소흡착에 의한 PVT 법과 0.1 M TEAP의 지지전해질과 유리질 탄소전극을 사용한 순환 전압전류법으로 1:1 oxygen adduct인 superoxo 착물들은 $O_2$-의 prewave가 없는 3단계 환원과정으로만 일어나는 것으로 확인할 수 있었다.

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서양의학의 Gout와 한의학(韓醫學)의 통풍(痛風)의 비교고찰(比較考察) (Compare Gout with Tongp'ung(痛風))

  • 김동욱;김갑성
    • Journal of Acupuncture Research
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    • 제17권4호
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    • pp.100-112
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    • 2000
  • Compare western medicine report and books which refer to Gout with Oriental medicine books which refer to Tongp'ung(痛風). The results of studying about Gout and Tongp'ung(痛風) were summarized as follows. l. Dangyesimbub(丹溪心法) was printed in 1481 and also the first book which referred to Tongp'ung(痛風). 2. Donwonsipjonguiso(東垣十種醫書) was printed in 1592 and also Tongp'ung(痛風) was recorded like gout especially in cause of disease. 3. Ancient times, Affection by exopathogen and six kinds of natural factors were persisted the cause of Tongpung(痛風), later generation drink, diet and labor were persisted. 4. In Beunjungrok(辨證錄) and susyebowon(壽世保元), there were similar expressions about gout, for examples interval phase and chornic tophaceous. 5. In Uihakjongjon(醫學正傳) and Manbeunghoechun(萬病回春) insisted that gout patients had to control their food especially meat, fish snd drink. 6. According to the cause(Pung(風), Han(寒), Sub(濕)), doctor classified Bi(痺) first was Hangbi(行痺), second was Tongbi(痛痺) and last was Chakbi(着痺). 7. Doctors thought that Tongp'ung(痛風,) was not Hangbi(行痺) and Chakbi(着痺) but it was Tongbi (痛痺). Especially in pain, they thought it was similar to Bakhoyeukjolp'ung(白虎歷節風).

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상부복외측 연수 심혈관계 세포의 체성교감 반사시 자발적 흥분발사특성 분석 :II. 최소 세포망 모델 (Spontaneous Firing Characteristics of Cardiovascular Neurons in the Rostral Ventrolateral Medulla during Somatosympathetic Reflex . 11. Minimal Neuronal Model)

  • 구용숙;노진아;차은종
    • 대한의용생체공학회:의공학회지
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    • 제17권1호
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    • pp.79-84
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    • 1996
  • A number of experimental evidences suggest that the rnun ventrolateral medulla(RVLM) is the final common pathway in the regulation of arterial blood pressure. A Voup of neurons in the RVLM, called the cardiovascular neurons (UN), show spontaneous activity temporally synchronized with the periodic cardiac cycle. These neurons affect the sympathetic nerve discharge(SND), thus are believed to be responsible for blood pressure control. The present experiment identified 98 UVNs in 42 cats based on the temporal relationships between each neuron's activity with both the cardiac cycle and SWD. In 20 UWL changes of spontaneous firing rate(FR) during the somatosympathetic reflex(SSR) were studied Five different firing patterns were observed during the pressor and depressor responses of SSR, implying that they form an interconnected neuronal circuit interacting with one another to generate efferent signals for blood pressure regulation. In the following companion paper, the firing patterns of CVN are analyzed to develop a minimal neuronal circuit model explaining the present experimental outcome.

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상부복외측 연수 심혈관계 세포의 체성교감반사시 자발적 흥분발사특성 분석 : I. 실험적 연구 (Spontaneous Firing Characteristics of Cardiovascular Neurons in the Rostral Ventrolateral Medulla During Somatosympathetic Reflex : II. Minimal Neuronal Model)

  • 차은종;구용숙;이태수
    • 대한의용생체공학회:의공학회지
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    • 제17권1호
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    • pp.71-80
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    • 1996
  • A number of experimental evidences suggest that the rnun ventrolateral medulla(RVLM) is the final common pathway in the regulation of arterial blood pressure. A Voup of neurons in the RVLM, called the cardiovascular neurons (UN), show spontaneous activity temporally synchronized with the periodic cardiac cycle. These neurons affect the sympathetic nerve discharge(SND), thus are believed to be responsible for blood pressure control. The present experiment identified 98 UVNs in 42 cats based on the temporal relationships between each neuron's activity with both the cardiac cycle and SWD. In 20 UWL changes of spontaneous firing rate(FR) during the somatosympathetic reflex(SSR) were studied Five different firing patterns were observed during the pressor and depressor responses of SSR, implying that they form an interconnected neuronal circuit interacting with one another to generate efferent signals for blood pressure regulation. In the following companion paper, the firing patterns of CVN are analyzed to develop a minimal neuronal circuit model explaining the present experimental outcome.

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마산시 도로 주변 은행나무와 양버즘나무의 잎과 수피 및 토양의 중금속 함량 (Contents of Heavy Metals in Leaf and Bark of Ginkgy biloba snd Platatus occidentalis and Soil of Roadside in Masan City)

  • Cheon, Seon-Hee;Jong-Hee Kim
    • The Korean Journal of Ecology
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    • 제19권3호
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    • pp.241-249
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    • 1996
  • To determine the accumulation and distribution of heavy metals in plants and soils of roadsides, the leaf and bark of Ginkgo biloba and Platanus occidentalis, and the soil were sample from Masan-city roadside and Chinhae forest land in July and November, 1994. The content of heavy metals from all the samples in Masan-city area was much higher than that in Chinhae forest land. The amount of heavy metals in soil was higher than those in plant parts of boty trees. The total amount of heavy metals of the bark was higher than the leaf of G. biloba plants. But that of the bark was less than the leaf of P. occidentalis. Heavy metal content in plants (leaf, bark) varied among elements and collections. The concentrations of heavey metals in both trees were in the order of Zn > Cu > Pb > Cd. The concentrations of the four heavy metals in leaf and Zn in soil in G. Biloba were seasonally changed. Whereas those in P. occidentalis were not significantly changed. And there was a high correlation between the concentrations of Pb and Cu in both trees.

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A2O SBBR에서 비포기 시간 배분에 따른 질소-인 제거 특성 비교 (A Comparison of N and P Removal Characteristics by the Variation of Non-aeration Time in A2O SBBR)

  • 박영식;정노성;김동석
    • 한국환경과학회지
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    • 제16권7호
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    • pp.813-821
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    • 2007
  • Laboratory scale experiments were conducted to investigate the removal characteristics of nitrogen and phosphorus in two sequencing batch biofilm reactors (SBBRs). SBBR1 had a short first non-aeration period and SBBR2 had a long first non-aeration period. The removal characteristics of nitrogen and phosphorus in each SBBR were precisely observed according to the variation of influent TOC concentration, and the operation control parameters (pH, DO concentration, ORP) in each reactor were measured. In biological nitrogen removal, there was little difference between SBBR1 and SBBR2 and the nitrogen removal efficiencies were very low. The nitrogen and phosphorus removal characteristics in high influent TOC concentration were different from those in low TOC. Nitrogen removals by simultaneous nitrification/denitrification (SND) were occurred in both SBBR1 and SBBR2. The P removal in SBBR1 was superior to that in SBBR2. The second P release was observed in SBBR1 which had long second non-aeration period.

Dependence of spacecraft anomalies at different orbits on energetic electron and proton fluxes

  • Yi, Kangwoo;Moon, Yong-Jae;Lee, Ensang;Lee, Jae-Ok
    • 천문학회보
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    • 제41권1호
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    • pp.45.2-45.2
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    • 2016
  • In this study we investigate 195 spacecraft anomalies from 1998 to 2010 from Satellite News Digest (SND). We classify these data according to types of anomaly : Control, Power, Telemetry etc. We examine the association between these anomaly data and daily peak particle (electron and proton) flux data from GOES as well as their occurrence rates. To determine the association, we use two criteria that electron criterion is >10,000 pfu and proton criterion is >100 pfu. Main results from this study are as flows. First, the number of days satisfying the criteria for electron flux has a peak near a week before the anomaly day and decreases from the peak day to the anomaly day, while that for proton flux has a peak near the anomaly day. Second, we found a similar pattern for the mean daily peak particle (electron and proton) flux as a function of day before the anomaly day. Third, an examination of multiple spacecraft anomaly events, which are likely to occur by severe space weather effects, shows that anomalies mostly occur either when electron fluxes are in the declining stage, or when daily proton peak fluxes are strongly enhanced. This result is very consistent with the above statistical studies. Our results will be discussed in view of the origins of spacecraft anomaly.

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Evaluation of a moving bed biofilm reactor for simultaneous atrazine, carbon and nutrients removal from aquatic environments: Modeling and optimization

  • Derakhshan, Zahra;Ehrampoush, Mohammad Hassan;Mahvi, Amir Hossein;Dehghani, Mansooreh;Faramarzian, Mohammad;Ghaneian, Mohammad Taghi;Mokhtari, Mehdi;Ebrahimi, Ali Asghar;Fallahzadeh, Hossein
    • Journal of Industrial and Engineering Chemistry
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    • 제67권
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    • pp.219-230
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    • 2018
  • The present study examined a moving bed biofilm reactor (MBBR) bioreactor on a laboratory scale for simultaneous removal of atrazine, organic carbon, and nutrients from wastewater. The maximum removal efficiency of atrazine, chemical oxygen demand (COD), total phosphorus (TP) and total nitrogen (TN) were 83.57%, 90.36%, 90.74% and 87.93 respectively. Increasing salinity up to 40 g/L NaCl in influent flow could inhibit atrazine biodegradation process strongly in the MBBR reactor.Results showed that MBBR is so suitable process for efficiently biodegrading of atrazine and nitrogen removal process was based on the simultaneous nitrification-denitrification (SND) process.