• Toxicological Research
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• v.24 no.1
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• pp.11-15
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• 2008

In this research the genotoxic effect of $Polycan^{TM}$ ${\beta}$-glucans originated from Aureobasidium pullulans SM-2001, was evaluated using the mouse micronucleus test. $Polycan^{TM}$ was administered once a day for 2 days by oral gavage to male ICR mice at doses of 1000, 500 and 250 mg/kg. Cyclophosphamide was used as a known genotoxic agent in a positive control group. The appearance of a micronucleus is used as an index for genotoxic potential. The results obtained indicated that $Polycan^{TM}$ shows no genotoxicity effect up to 1000 mg/kg dosing levels. In addition, it is also considered that there were no problems from cytotoxicity of $Polycan^{TM}$ tested in this study because the polychromatic erythrocyte ratio was detected as > 0.47 in all tested groups.

• Journal of the Korean Society for Precision Engineering
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• v.7 no.3
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• pp.75-82
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• 1990

Automatic monitoring of the cutting conditions is one of the most improtant technologies in machining. In this study, the feasibility in applying acoustic emission(AE) signals for the in-process detection of endmill wear and fracture has been investigated by performing experimental test on the NC vertical milling machine with SM45C for specimen. As the results of detecting and analyzing AE signals on various cutting conditions, the followings have confirmed. (1) The RMS value of acoustic emission is related sensitively to the cutting velocity, but is not affected largely by feed rate. (2) The burst type AE signals of high level have been observed when removing chips distorderly and discontinuously. (3) When the RMS value grows up rapidly due to the increase of wear the endmill are generally broken or fractured, but when the endmills fracture at the conditions of smooth chip-flow or built-up-edge(BUE) occurred frequently, the rapid change of the RMS arenot found. And it is expected that this technigue will be quite useful for in-process sensing of tool wear and fracture.

• Journal of Photoscience
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• v.12 no.2
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• pp.87-93
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• 2005

A new assay technique to distinguish between pure compounds and the isomeric mixtures has been suggested using single molecule (SM) fluorescence detection technique. Since the number of emission spots in a fluorophorespread film prepared from a genuine dye solution was determined by experimental condition, the deviation of spot numbers from the expected values could be considered to be an indication of lower purity of the sample solution. The lower limit of sample concentration for this assay was determined to be $5{\times}10^{-10}$ M to show uniform number of expected spots within 10% uncertainties in our experimental condition. An individual fluorescence intensity distribution for a mixture of isomers having doubly different emissivities was simulated by adding distributions obtained from Cy3 and nile red (NR) independently. The result indicated that the mixture could be identified from the pure compounds through the difference in the number of Gaussian functions to fit the distribution. This new assay technique can be applied to the purity test for synthetic biofluorophores which are usually prepared in small quantities not enough for classical ensemble assays.

• Journal of the Korean Society of Safety
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• v.19 no.2
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• pp.47-53
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• 2004

Emulsion polymerization ws carried out using Alkyl methacrylate(RMA) like MMA, EMA, BMA and Styrene Monomer(SM) for core-shell latex preparation. It was synthesized at $80^{\circ}C$ in the presence of anionic surfactant SLS(Sodium Lauryl Sulfate). FT-IR and DSC analysis are used to confirm the synthesized core-shell emulsion latexes. Moreover DSC and TGA were used to investigate the thermal characterisitcs of them. The differences of the decomposition rate and the activation energy from TGA and DSC analysis are not so big. It considers that the pendent group is not affect of the thermal characteristics and stability on core-shell latexes, which is synthesized with RMA and Styrene. For investigating combustion products, LC50 values were calculated by FED(Fractional Effective Dose)from the Pyrolyzer-Mass sepctrometer.

• Strategy21
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• s.42
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• pp.196-223
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• 2017

The aim of this paper is to analyze China's naval strengthening and threat reflected in submarines, aircraft, destroyers and missile capabilities and US Navy's counter-forces. China is strengthening its naval forces in accordance with its three-step naval force build-up plan, and the introduction of Russian destroyers and submarines is a foothold for China's naval enforcement. The Chinese Navy also converted the concept of the First-Second Island Chain Defense, which it had already maintained, to the concept of maritime layer defense. Currently, the Chinese Navy maintains the concept of a Three-Maritime Layer Defense which includes the South China Sea, where artificial islands are being built by China, in the First Layer Defense and the East China Sea in the Third Layer Defense. Along with the advancement of Chinese Navy's submarines, surface vessels and aircraft's operational capabilities, ballistic and cruise missile capabilities become a major threat to the US Navy. If a crisis occurs in the East China Sea or in the Taiwan Waters, the US Navy will face more difficulties in employing the Carrier Strike Group to manage the crisis. Meanwhile, if a crisis occurs on the Korean Peninsula, it will be a burden to dispatch Carrier Strike GroupS to the East and West Seas of the Korean Peninsula. For the stable future, the US Navy should develop a strategy to respond more effectively to the Chinese Navy, which is challenging new maritime supremacy in East Asia.

• YAKHAK HOEJI
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• v.35 no.2
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• pp.61-72
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• 1991

These studies were made to assess the present stage of resistance to antibiotics, incidence and transferability of R-factors against E. coli. From March to July 1987, 59 strains of E. coli were isolated from specimens of patients collected at university hospitals in Seoul, 64 strains from stools of domestic animals and 66 strains from drainages in Seoul. These specimens were tested for resistance to 12 kinds of antimicrobial agents by means of agar dilution method. Using Muller-Hinton agar for the assay of drug resistance and tryptic soy broth as propagating medium for conjugation. The strains of E. coli were found to be resistant to one or more antibiotics and were considered to be potential donors of R-plasmid. The resistant strains of E. coli isolated from patients, domestic animals and drainages were found to be 55(93%), 33(52%) and 31(47%), respectively. Resistance to Tc, Ap and Cb was the highest in those isolated from patients and drainages, and resistance to Tc, Cm and Sm was the highest in those isolated from domestic animals. In the transfer test of drug resistance by conjugation method, 17 strains (47%) isolated from patients, 15(54%) isolated from domestic animals and 15(56%) isolated from drainages showed positive results, transperable resistant plasmid molecules with variable range in each strain.

• Current Industrial and Technological Trends in Aerospace
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• v.6 no.2
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• pp.60-68
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• 2008

The characteristic and properties of materials are rapidly degraded when subjected to the synergistic effects of the space environment such as atomic oxygen, radiation, vacuum and thermal cycling. In order to understand the mechanism of material property variation in space environment and to develop new space materials applicable to the future space program, advanced space organizations such as NASA, ESA and JAXA have been continuing many researches on material test specimens used on ISSE(International Space Station Experiment) or LDEF(Long Duration Exposure Facility). In this paper, the selection requirements and verification trend of materials in space applications

• Proceedings of the KIEE Conference
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• 2000.07e
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• pp.29-32
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• 2000

Ozone has been widely applied to many industrial fields because of its strong oxidation effects. Therefore, the studies have been progressed for the effective and high concentration of one generation. The silent or surface discharge have been mainly used for high concentration ozone generation until now. But these two types of ozone generators have shortcomings to be improved. In this study, the ozone generator which improved the shortcomings of above two type of ozone generators was proposed and manufactured for high concentration ozone generation. And the proposed ozone generator could generate the surface and barrier discharge simultaneously. For this purpose, a mesh type discharge electrodes were proposed and the experiments were fulfilled as a function of the widths and spacings of mesh electrodes and gap spacings between the dielectric barrier and mesh electrode. When the width of mesh electrode[WM] and spacing of mesh electrode[SM] are 0.3[mm] and 0.8[mm] respectively, the maximum ozone concentration of 2.96[vol%] was obtained at 5.6[kV], 830[mA], gap spacing (S)=0.65[mm].

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.13 no.1
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• pp.121-128
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• 2014

Superfinishing is essential for mirror surfaces, because among mechanical components cylindrical workpieces such as spindles must maintain precision and reliability with respect to functional characteristics. However, research on standardization of polishing film application combination to obtain mirror surfaces is insufficient. Consequently, this has been a factor in rising costs of mechanical components. Therefore, in this study, experiments have been conducted to determine efficient polishing film application combination for mirror surfaces ranging from ductile materials such as SM45C, brass, aluminium 7075, and titanium to brittle materials such as $Al_20_3$, SiC, $Si_3N_4$, and $ZrO_2$. From the experimental results, efficient polishing film application combination for metallic materials and ceramic materials is confirmed.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 1997.04a
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• pp.1068-1072
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• 1997

This work deals with on investigation the influence of various additives to a base stock cutting fluid in order to develop a better deep hold drilling. This investigation has been aiming at developing an oil which gives a maximum cutting efficiency at a minimum wear rate of the tool and the guiding pads. The purpose of study is to analyze how guide pad of tools, workpiece and the change of contained quantity of extreme pressure additive in cutting fluids have effects on the hold over size of cutting hole, surface roughness of workpiece,wear rates of guide pad and roundness during the deep hole machining of SM55C with solid BTA drill by using BTA drilling system through experiment. Conclusion reached is as follows. It has been proved that the contained quantity of surphur more affects machinability than that of extreme pressure additive of chlorine of cutting fluid in BTA drilling during Deep Hole Drilling. Considering its base oil, the the contained quantity of extreme pressure assitive of surphur can be different, but it's judged that the range of 1.5 ~ 2.0% is suitable to machinability for workpiece in BTA drilling. Regarding guide pad, it's judged that the reduction of wear is possible in propotion to the contained quantity of exrreme pressure additive of chlorine against supporting of cutting force and Bumishing operation of machining parts in cutting.