• Journal of the Korean Society of Hazard Mitigation
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• v.8 no.2
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• pp.139-147
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• 2008

More precise estimation of the bed change, primary cause of flood damage, has been recognized significant for designs of levees and other river facilities. In this study, the long-term bed change was examined as the application of the relatively new Surface-water Modeling System (SMS) Model because there has not been broad verification of the model empirically on river of South Korea. This 2-dimensional model was used to examine the bed change of Pochon Stream Basin, a tributary of Imjin River, where heavy rain damages annually occur. First, in order to verify the model, the simulating period was set from 1986 to 1998 because of the existence of the field measurements. Cross sectional field measurements of 1986 were used for the initial condition and output were compared and analyzed with the observed cross sectional data in 1998. As the results of the verification, the comparison in lateral and streamwise bed level between results from the model and the field measurements showed a reasonable agreement except for the some cases of local scours. However, in terms of the quantitative comparison, the change of the bed elevations for each cross section for 1998 was rather underestimated than that of the field measurements.

• Economic and Environmental Geology
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• v.31 no.3
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• pp.249-264
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• 1998

The Creataceous volcanic rocks distributed in the southeastern part (Kyeongsang basin) of Korea peninsula are composed of basalt, basaltic andesite, andesite, dacite and rhyolite. The variation of major elements show that contents of MgO, CaO, $FeO^T$, $Al_2O_3$, $TiO_2$ and $P_2O_5$ decrease with increasing of $SiO_2$, but $K_2O$ contents are increased slightly, $Na_2O$ widely dispersed. We can show slightly inflection point and low frequency of dacites in range between 63-65 wt.% $SiO_2$, while continuous trend exit in variation diagram. Variation trends in Harker diagrams for the major, minor, trace and REEs suggest that the BAV (basaltic to andesitic volcanics) and DRV (dacitic to rhyolitic volcanics) are not related to a simple crystal fractionation process. In the regime of under 65 wt. % in silica content, fractionation of olivine and clinopyroxene is predominant, while that of plagioclase happens strongly higher than 65 wt.% (e.g., $SiO_2$, vs. Eu and Sr, MgO vs. $Al_2O_3$ and CaO). The latter means low-pressure fractional crystallization for DRV. On the discriminant diagram, DRV are located in more mature environment than BAV. The $(Ce/Sm)_N$ vs. CeN digram shows that these two classes cannot be related to crystal fractionation. If they had been produced by fractionation, although they plotted in a slightly elongate cluster along the same horizontal trend, DRV should lie to the right of these primitive compositions. These diagrams clearly rule out a simple fractionation throughout from BAV to DRV. BAV had been influenced greatly subductiong slab as shown by K/Yb vs. Ta/Yb. We suggest that BAV primitive magma generated higher degree of partial melting than DRV primitive magma. LILE (K, Ba, $Rb{\pm}Th$) enriched characteristics as shown in BAV are inherited from subducting slab fluids and/or higher degree of partial melting of mantle material. However, lower degree of partial melting of mantle relative to BA V and contamination at high-level magma reservoir caused LILE enrichment to DRV.

• Reproductive and Developmental Biology
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• v.37 no.4
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• pp.219-224
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• 2013

Muscular satellite cell (SC), which is stem cell of postnatal pig, is an important for study of differentiation into adipogenesis, myogenesis, and osteoblastogenesis. In this study, we isolated and examined from pig muscle tissue to determine capacity in proliferate, differentiate, and expression of various genes. Porcine satellite cells (PSC) were isolated from semimembranosus (SM) muscles of 90~100 days old pigs according to standard conditions. The cell proliferation increased in multi-potent cell by Masson's, oil red O, and Alizarin red staining respectively. We performed the expression levels of differentiation related genes using real-time PCR. We found that the differentiation into adipocyte increased expression levels of both fatty acid binding protein 4 (FABP4) and peroxisome proliferator-activated receptor gamma ($PPAR{\gamma}$) genes (p<0.01). Myocyte increased the expression levels of the myosin heavy chain (MHC), myogenic factor 5 (Myf5), myogenic regulatory factor (MyoD), and Myogenic factor 4 (myogenin) (p<0.01). Osteoblast increased the expression levels of alkaline phosphatase (ALP) (p<0.01). Finally, porcine satellite cells were induced to differentiate towards adipogenic, myogenic, and osteoblastogenic lineages. Our results suggest that muscle satellite cell in porcine may influence cell fate. Understanding the progression of PSC may lead to improved strategies for augmenting meat quality.

• Strategy21
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• s.37
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• pp.242-274
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• 2015

2015년 5월 수중발사 탄도미사일(SLBM) 발사시험을 통해 북한은 전 세계의 이목을 또 다시 집중시켰다. 북한은 2013년 제3차 핵실험을 감행한 이후 최근까지도 탄도미사일과 로켓 발사 등의 무력도발을 지속해 왔다. 이와 같은 북한의 무력도발은 한반도의 안정뿐만 아니라 미국 본토의 안보에도 매우 부정적인 영향을 미치고 있다. 지금까지 미국은 북한의 핵미사일 개발 저지를 위해 경제적 또는 군사적 방안들을 선별적으로 적용해 왔다. 그러나, 이러한 미국의 노력에도 불구하고 북한은 여전히 핵미사일을 개발하겠다는 꿈을 포기하지 않고 있는 것이 사실이다. 본 논문은 북한의 핵미사일 개발에 대한 미국의 대안적 전략(Alternative Strategy)을 제시하는데 그 목적이 있다. 필자는 대안적 전략 제시에 앞서 북한의 핵과 탄도미사일 개발현황을 내용(Contents)과 맥락(Context) 차원에서 분석하고 미 오바마 행정부의 대북전략을 비판적으로 검토하였다. 그리고 대안적 전략으로 동맹국과 함께 경제적(Sticky Power), 군사적(Sharp Power) 수단의 동기화(Synchronizing)를 통해 북한이 감당하기 힘든 전략적 환경을 조성(Shaping the Strategic Environment)하는 것이 '북한의 핵개발 포기' 라는 전략목표를 달성하는 방안 임을 강조하고 있다. 미국이 대안적 전략목표를 달성하기 위해서는 경제적 수단으로 ① 북한의 자금세탁 및 위조지폐 발행국 지정, ② 북한을 지원하는 모든 해외자산에 대한 제재조치, ③ 북한의 테러지원국 재지정, ④ 북한 제재를 위한 미국의 입법추진, ⑤ 대량살상무기 관련 금수품목의 확대를 적용함과 동시에 군사적 수단으로 ① 대량살상무기 비확산 활동 강화, ② 대탄도미사일 전략 개발 및 정보(ISR: Intelligence Surveillance and Reconnaissance) 공유, 맞춤형 억제전략(TDS: Tailored Deterrence Strategy)의 구체화 등을 통한 한·미 군사 억제방안의 강화, 그리고 ③ SM-3, THAAD(Terminal High Altitude Area Defense) 등 한·미·일 3자간 MD(Missile Defense)체제의 구축 등을 동기화하여 적용해야만 할 것이다. 미국의 대안적 전략은 ① 북한의 핵미사일 개발에 대한 중국의 협력방지, ② 한·중간 경제관계의 악화, ③ 한·일간의 역사적 긴장관계라는 위험요소를 내포하고 있는 것 또한 사실이다. 따라서 미국이 대안적 전략목표인 '북한의 비핵화' 달성을 위해서는 이와 같은 위험요소를 완화시키는 노력도 병행되어야 할 것이다. 끝으로, 미국은 북한의 김정은이 핵미사일 개발 포기라는 상이한 방향의 전략적 결정을 할 경우에 대비하여 한·미 연합훈련의 보류, 북한에 대한 경제제재조치 해제 등 북한과의 협상 가능성도 열어두고 이에 대해서도 철저하게 준비해 나가야 할 것이다.

• Restorative Dentistry and Endodontics
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• v.32 no.4
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• pp.313-326
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• 2007

The purpose of this study was to prove that an intermediate resin layer (IRL) oan increase the bond strength to dentin by reducing the permeability of single-step adhesives. Flat dentin surfaces were created on buccal and lingual side of freshly extracted third molar using a low-speed diamond saw under copious water flow. Approximately 2.0 mm thick axially sectioned dentin slice was abraded with wet #600 SiC paper. Three single-step self-etch adhesives; Adper Prompt L-Pop (3M ESPE, St Paul, MN, USA), One-Up Bond F (Tokuyama Corp, Tokyo, Japan) and Xeno III (Dentsply, Konstanz, Germany) were used in this study. Each adhesive groups were again subdivided into ten groups by; whether IRL was used or not; whether adhesives were cured with light before application or IRL or not; the mode of composite application. The results of this study were as follows; 1. Bond strength of single-step adhesives increased by an additional coating of intermediate resin layer, and this increasement was statistically signigicant when self-cured composite was used (p < 0.001). 2. When using IRL, there were no difference on bond strengths regardless the curing procedure of single-step adhesives. 3. There were no significant difference on bond strengths between usage of AB2 or SM as an IRL. 4. The thickness of Hybrid layer was correlated with the acidity of adhesive used, and the nanoleakage represented by silver deposits and grains was examined within hybrid and adhesive layer in most of single-step adhesives. 5. Neither thickness of hybrid layer nor nanoleakage were related to bond strength.

• Journal of Korea Water Resources Association
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• v.45 no.12
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• pp.1293-1307
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• 2012

This study is to evaluate the RHESSys (Regional Hydro-Ecological Simulation System) simulated streamflow (Q), evapotranspiration (ET), soil moisture (SM), gross primary productivity (GPP) and photosynthetic productivity (PSNnet) with the measured data. The RHESSys is a hydro-ecological model designed to simulate integrated water, carbon, and nutrient cycling and transport over spatially variable terrain. A 8.5 $km^2$ Seolma-cheon catchment located in the northwest of South Korea was adopted. The catchment covers 90.0% forest and the dominant soil is sandy loam. The model was calibrated with 2 years (2007-2008) daily Q at the watershed outlet and MODIS (Moderate Resolution Imaging Spectroradiometer) GPP, PSNnet and 3 year (2007～2009) daily ET data measured at flux tower using the eddy-covariance technique. The coefficient of determination ($R^2$) and the Nash-Sutcliffe model efficiency (ME) for Q were 0.74 and 0.63, and the average $R^2$ for ET and GPP were 0.54 and 0.93 respectively. The model was validated with 1 year (2009) Q and GPP. The $R^2$ and the ME for Q were 0.92 and 0.84, the $R^2$ for GPP were 0.93.

• Korean Journal of Soil Science and Fertilizer
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• v.47 no.4
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• pp.269-274
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• 2014

Series of field experiments were conducted to evaluate the long term effect of gypsum and crop residue on crop yield and soil health in rice-wheat crop rotation system in salt affected soil. A saline-sodic field having $EC_e$ (electrical conductivity of the saturation extract) 4.77 ($dSm^{-1}$); pH ($H_2O$) 8.96; SAR 43.78 ($mmol\;L^{-1}$) and gypsum requirement (G.R.) 2.86 (Mg $acre^{-1}$) was selected on Soil Salinity Research Institute Farm. Five treatments consisting of ($T_1$) control, ($T_2$) gypsum at 100% G.R., ($T_3$) gypsum at 25% G.R. + wheat straw at $3Mg\;ha^{-1}$, ($T_4$) gypsum at 25% G.R. + rice straw at $3Mg\;ha^{-1}$, ($T_5$) gypsum at 25% G.R.+ rice and wheat straw at $3Mg\;ha^{-1}$ were replicated four times under completely randomized block design. The data indicated that grain and straw yield of rice and wheat was significantly (P<0.05) increased by all the amendments used either single or in combination. $T_2$ (gypsum at 100% G.R.) significantly (P<0.05) increased grain and straw yield of rice and wheat crops followed by $T_3$ (gypsum at 25% G.R. + wheat straw at $3Mg\;ha^{-1}$) when compared with control. Soil properties were also improved by used amendments, pronounced decreased in $EC_e$, $pH_s$ and SAR were recorded in $T_2$ followed by $T_3$. The efficiency of the treatments could be arranged in following order gypsum at 100% G.R.> gypsum at 25% G.R. + wheat straw at $3Mg\;ha^{-1}$ > gypsum at 25% G.R. + rice and wheat straw at $3Mg\;ha^{-1}$ > gypsum at 25% G.R. + rice straw at $3Mg\;ha^{-1}$ > control.

• Proceedings of the Korean Society of Applied Pharmacology
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• 2001.04a
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• pp.115-126
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• 2001

1988년 Reaven이 인슐린저항성증후군(insulin resistance syndrome)의 개념을 처음 소개한 후 전세계적으로 관심이 증가하고 있다. 인슐린저항성증후군은 대사성증후군 (metabolic syndrome), X 증후군(syndrome X)이라고도 하며, 인슐린 저항성에 따른 고인슐린혈증, 내당능장애(impaired glucose tolerance)와 2형 당뇨병(인슐린 비의존형 당뇨병), 이상지질혈증(dyslipidemia), 고혈압 등 일련의 질환은 동일인에서 흔히 병발하고, 이들은 모두 죽상경화증(atherosclerosis)의 위험인자라는 관점에서 상호연관성을 갖는 질환군이라는 개념이다. 2형 당뇨병은 인슐린에 대한 말초조직의 저항성과 상대적으로 감소된 인슐린 분비능의 결과라고 할 수 있다. 또한 상당수의 2형 당뇨병은 비만, 특히 복부비만을 동반하고 있으며, 비만은 그 자체로 인슐린 저항성을 유발한다. 결국 인슐린 저항성이 장기간 개선되지 못하게 되면 2형 당뇨병이 유발되게 된다. 따라서 2형 당뇨병에 대한 최선의 치료는 혈당조절 뿐만 아니라 인슐린 저항성과 관련된 심혈관계 위험인자를 개선시키는 것을 목표로 해야 한다. 그 증거로 당뇨병 조절과 관련한 대규모 전향적 연구인 UKPDS(United Kingdom Prospective Diabetes Study)의 결과를 보면, 2형 당뇨병에서 설폰요소제(sulfonylurea)나 인슐린으로 10년동안 혈당조절을 했을 때 미세혈관 합병증은 의미있게 감소시켰으나 대혈관 합병증의 발생률은 의미있는 감소를 보이지 못하였다. 반면 대혈관 합병증이 미세혈관 합병증보다 사망에 기여하는 비율이 70배 이상이라는 사실은 당뇨병의 치료가 혈당조절에만 초점이 맞추어져서는 안 되며 심혈관계 위험인자를 개선시키는 치료가 동시에 진행되어야 한다는 점을 시사한다.시료에서 매우 드물게 관찰된다. 음극선발광(cathodoluminescence) 영상의 해석을 통해 저어콘 결정의 성장사를 유추하였으며, 이를 바탕으로 이온현미분석 점(spot)을 정하였다. U-Pb-Th 자료는 퍼스(Perth) 저어콘 스탠다드 (CZ3, 564 Ma, $^{206}$Pb/$^{238}$U=0.0914)를 사용하였다. 아래에 기술하는 연대는 모두 $^{206}$Pb/$^{238}$U 연대에 해당된다. 두 개의 화강암질 편마암 시료로부터 구한 U-Pb 저어콘 연대는 각각 812 $\pm$ 14 Ma(1006-8)와 822 $\pm$ 17 Ma(1006-9)로 분석오차 내에서 서로 일치한다. 이 결과는 춘천 및 전곡 지역의 석류석 각섬암에서 보고된 Sm-Nd 전암연대(852 $\pm$ 24 Ma 및 824 $\pm$ 143 Ma; Lee and Cho, 1995; Ree et al., 1996)와 잘 부합한다. 따라서 후기 원생대 기간 중 화성활동이 한반도에서 광범위하게 일어났음을 시사한다. 한편, 1006-9 시료에서는 예외적으로 한 개의 저어콘 입자 주변부(rim)에서 매우 얇은 과성장띠가 관찰되었으며, 두 개의 점 분석으로부터 구한 U-Pb 저어콘 연대는 약 235 Ma이다. 이 띠는 또한 변성기원의 저어콘에서 흔히 관찰되는 작은 W (<0.05) 비를 보인다. 1006-5 시료는 위 두 시료로부터 수 km 떨어진 지점에서 채집하였으나, 저어콘 연대는 상이한 기록을 보여준다. 즉 매우 작은 Th/U (<0.01) 값을 갖는 저어콘의 주변부에서 223 $\pm$ 5 Ma의 연대가 잘 정의되며, 이는 1006-9 시료에서 관찰된 결과와

• Journal of the Korean Society for Precision Engineering
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• v.3 no.2
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• pp.62-75
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• 1986

An experimental investigation of the machining characteristics such as cutt- ing resistance, surface roughness and tool wear in turning the test pieces of SM45C steel with both coated and uncoated carbide tool tips under various cutting conditions was conducted. Also a specially designed simple vibration damping device was experimentally evaluated for its effectiveness on machined surface roughness and a vibration test was conducted to confirm its ability to reduce the amplitude. Based on these tests finding, the following conclusions are made; 1. The cutting resistance($\textrm{p}_{1}$) increases as the depth of cut(d) increases at fixed feed rate(f) over the cutting speed(v) range of 43-226 m/min and p decreses about 18% average when V is increased for fixed d and f. At V= 226m/min, $\textrm{p}_{1}$/for A, C tips are about the same level but $\textrm{p}_{1}$ for B tip is 15% less than A, C tips. 2. The specific cutting resistance(Ks) at V=226 m/min was derived for A, B, C tips respectively and the value of Ks for B rip is about 20% less than A, C tips. 3. The surface roughness(Ra) improves significantly as the cutting speed(V) is increased and this effect was greater when V>100 m/min. On the other hand, Ra deteriorates as the feed rate(f) is increased and this trend was accelerated when f>0.3 mm/rev. With regard to the difference of Ra values among A, B, C tips, at V=226m/min, d=0.4mm, and f=0.31-0.61mm/rev, Ra values for B.C tips are about 17% less than tip A. 4. The experimental tool wear equations were derived for A, B, C tips and from these equations, the tool life($\textrm{T}_{\textrm{L}}$) baced on the I.S.O. criteria was calculated to be $\textrm{T}_{\textrm{L}}$<$\textrm{T}_{\textrm{LB}}$<$\textrm{T}_{\textrm{LC}}$ for both flank wear($\textrm{V}_{\textrm{B}}$) and boundary wear($\textrm{V}_{\textrm{N}}$). Hence, the coated tips are superior to the uncoated tip and tip C is considered to be the best. 5. The cutting resistance may be slightly reduced and the surface rounghness improved when the damper is used especially when V>100 m/min. Therefore this damping device is considered to be effective and practical. The experimental surface roughness equations were also derived. Based on the vibration test, it is established that the surface roughness improvement was the result of amplitude reduction made possible by the damper.

• Korean Journal of Food Science and Technology
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• v.46 no.5
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• pp.556-565
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• 2014

In this study, we evaluated changes in physicochemical properties, total phenol and isoflavone contents, and antioxidant activity during soymilk fermentation by a potential probiotic Lactobacillus plantarum P1201. The P1201 strain showed survival rates of 58.14% and 62.22% after 4 h exposure to acid and artificial gastric acid conditions (pH 2.5), respectively. The optimal conditions for soy-yogurt fermentation by L. plantarum were determined to be as follows: temperature of $35^{\circ}C$, seed volume of 5.0%, and sucrose content of 10.0%. The total phenol and isoflavone contents and antioxidant activity were higher in soy-powder milk (SPM) yogurt than soymilk yogurt. In particular, the highest levels of isoflavone-aglycones, such as daidzein, glycitein, and genistein (91.50, 12.34, and $61.39{\mu}g/g$, respectively), were observed after 48 h of SPM fermentation. Thus, these results suggest that the soy-yogurt extract could be used as a potential source of natural antioxidants in food.