• Toxicological Research
• /
• v.20 no.3
• /
• pp.179-185
• /
• 2004

Helicobacter pylori (H. pylori) infects more than half of the people in the world as a major microbe to cause most of gastric diseases. Recently, cytotoxin associated-antigen A (CagA) is believed as one of the most important virulence factors of H. pylori. Molecular toxicological pathway of CagA is necessary to investigate for understanding the pathological and toxicological aspects of H. pylori, since this virulence protein harasses intercellular processes of host cells to get profit for the survival of H. pylori. CagA is coded from cag pathogenicity island (cag PAI) and translocated into host cells by Type 4 secretion system (TFSS). Tyrosine phosphorylation of CagA targets Src homology 2-containing phosphotyrosine phosphatase (SHP-2) to form a CagA-SHP-2 complex. This complex depends on the similarity of sequence between EPIYA motif and Src homology 2 domain (SH2 domain) of CagA. The generation of growth factors is an essential role of CagA in protecting and healing gastric mucosa for the survival of H. pylori. On the other hand, the activation of IL-8 by CagA induces neutrophils generating inflammation and free radicals. Indeed, free radicals are well known carcinogen to induce DNA damage. In addition, the transduction of mitogen-activation signal by CagA is one of the interesting features to understand how to cause cancer. The relationship between cancer and inflammation with CagA was mainly discussed in this review.

• Journal of IKEEE
• /
• v.8 no.1 s.14
• /
• pp.79-85
• /
• 2004

In this paper, Sub harmonic mixer using anti-parallel diode pair is designed for 5.8 GHz Wireless LAN. Conventional mixers mix LO with RF and obtain IF signal from the difference between LO and RF. As frequency increase, LO signal is required increasing LO power, better phase noise, stable LO. But, using APDP, the SHP mixer mix the harmonics of LO signal. Therefore, Sub harmonic mixer is advantage that necessary LO signal frequency was used to operate the 1/2. When LO power is 3 dBm, the conversion loss of manufactured SHP mixer is 12.83 dB. The isolation of LO/IF, 2LO/IF, RF/IF and LO/RF is 39.17 dB, 58 dB, 34 dB, 67.9 dB. And IIP3 is 8 dBm.

• Design & Manufacturing
• /
• v.11 no.3
• /
• pp.46-50
• /
• 2017

Press processing is one of the best machining methods capable of mass production, satisfying dimensional, shape and quality among the methods of processing a metal plate. Among them, Fine blanking is a method of obtaining a precise cross-section such as machining of the shear surface shape. In this research, Using SCP-1 and SHP-1 materials. The deformation behaviors of the material flow affecting the die height of the shear section in accordance with the position of the V-ring in the Fine blanking were compared and analyzed. Result of interpretation, It was confirmed that the force acts on the position where the material flow direction accurately forms the die roll that the material of SCP-1 is at a position of 1.5 mm and the material of SHP-1 is at 2.0 mm. As a result, it was confirmed that the state of fo1111ing the shear surface by the V-ring was excellent. Using analysis results, In the experiment, the height of the die roll was considered by applying The position of the V-ring was 1.5 mm in SCP-1 and 2.0 mm in SHP-1. As a result of comparing the height of the die rolls, the height values of the die rolls were different from each other, It has been considered that the tendency of the die rolls to coincide with each other. It is considered that the difference of the die roll height is caused by the pressure input of the V-ring. In this study, the deformation behavior of the material(In addition to the position of the V-ring, the flow direction of the material depends on the shape of the V-ring and the Indentation amount) is considered to be an important factor in determining die roll height.

• Animal cells and systems
• /
• v.1 no.4
• /
• pp.571-576
• /
• 1997

The playas of the Southern High Plains (SHP) of Texas, USA are an important habitat for over one million wintering waterfowl. However, the recent trend toward the modification of playas for agricultural use is threatening winter habitat of waterfowl in this region. Diurnal activity budgets of wintering mallards (Anas platyrhynchos) were conducted from 1 October to 31 March, 1983-1984, and 1984-1985) at three habitat types; steep-sided pits, terraced pits, and open lakes. All seven activity patterns (feeding, locomotion, resting, comfort, courtship, alert, and agonistic) were different (P<0.05) among the three habitat types for wintering mallards on the SHP of Texas. Terraced pits supported more feeding activity (27.8%) (P<0.001) than steep-sided pits (11.2%) or open lakes (2.6%) due to their abundance of natural seeds and aquatic invertebrates. Hens (17.5%) fed more than drakes (11.7%) (P<0.05). Locomotion (32.2%) and alert (2.8%) behavior across the three habitat types showed the highest level during the early morning (6:00-9:00 AM). Paired mallards rested more (37.9%) than unpaired mallards (25.8%) (P<0.05). Agonistic activity was highest (2.4%) in terraced pits throughout the season.

• Proceedings of the Zoological Society Korea Conference
• /
• 1996.10a
• /
• pp.255.2-255
• /
• 1996

No Abstract, See Full Text

• Journal of the Korean Society of Propulsion Engineers
• /
• v.10 no.2
• /
• pp.15-22
• /
• 2006

An intelligent performance diagnostic program using the Neural Network was proposed for PW206C turboshaft engine. It was selected as a power plant for the tilt rotor type Smart UAV(Unmanned Aerial Vehicle) which is being developed by KARI (Korea Aerospace Research Institute). For teeming the NN(Neural Network), a BPN(Back Propagation Network) with one hidden, one input and one output layer was used. The input layer has seven neurons: variations of measurement parameters such as SHP, MF, P2, T2, P4, T4 and T5, and the output layer uses 6 neurons: degradation ratios of flow capacities and efficiencies for compressor, compressor turbine and power turbine, respectively, Database for network teaming and test was constructed using a gas turbine performance simulation program. From application of the learned networks to diagnostics of the PW206C turboshaft engine, it was confirmed that the proposed diagnostics algorithm could detect well the single fault types such as compressor fouling and compressor turbine erosion.

• Proceedings of the Korean Society of Propulsion Engineers Conference
• /
• 2006.05a
• /
• pp.213-217
• /
• 2006

An intelligent performance diagnostic program using the Neural Network was proposed for PW206C turboshaft engine. It was selected as a power plant for the tilt rotor type Smart UAV (Unmanned Aerial Vehicle) which has been developed by KARI (Korea Aerospace Research Institute). For teaming the NN, a BPN with one hidden, one input and one output layer was used. The input layer had seven neurons of variations of measurement parameters such as SHP, MF, P2, T2, P4, T4 and T5, and the output layer used 6 neurons of degradation ratios of flow capacities and efficiencies for compressor, compressor turbine and power turbine. Database for network teaming and test was constructed using a gas turbine performance simulation program. From application results for diagnostics of the PW206C turboshaft engine using the learned networks, it was confirmed that the proposed diagnostics algorithm could detect well the single fault types such as compressor fouling and compressor turbine erosion.

• Journal of Biomedical Engineering Research
• /
• v.5 no.2
• /
• pp.121-126
• /
• 1984

A new approach to texture classification for quantitative ultrasound liver diagnosis using run difference matrix was developed. The run difference matrix comprised the gray level difference along with a distances. From this run difference matrix, we defined several vectors and parameters such as DOD, DGD, DAD vector, SHP, SMO, SMG, LDE, LDEL etc.Each parameter values calculated in fatty, cirrhotic, normal and chronic hepatitic liver images were plotted in a plane and we found that RDM method was more sensitive to small structural changes than the conventional run length method and showed improved classification ability between the diseases.

• The Magazine of Kiice
• /
• v.5 no.1
• /
• pp.77-81
• /
• 2004

최근 무선통신 시스템은 멀티미디어 서비스 요구의 증가와 무선전송기술 발달로 인하여 주파수자원이 고갈되고있다. 특히 면허가 필요 없는 특정 소전력 무선국 및 ISM 대역 개방에 의해 2.4 ㎓ 이하의 주파수 스펙트럼이 포화 상태에 있으며 5.8 ㎓ 대역과 무선 LAN 서비스간의 혼신 및 출력제한 등의 문제로 국내외적으로 전송속도와 주파수 효율이 우위에 있는 5㎓ 대역 주파수 활용방안에 대한 검토가 진행되어 왔다. (중략)

• Korean Journal of Animal Reproduction
• /
• v.15 no.1
• /
• pp.7-13
• /
• 1991

This study was carried out to investigate the effects of pH of sperm-washing solution, sperm-washing frequency and individual bull on concentration of hydrogen ion in sperm-washed solution and sperm acrosome reaction. The results obtained were as follow. 1. When bovine sperm was washed at 4 times with SHP solution and incubated, the difference of light absorbance between sperm-washing and sperm-washed solution(${\Delta}$Ao-${\Delta}$At) was higher in 2nd sperm-washed solution than that in the other washed solutions. 2. When sperm was thrice washed with SHP solutions of pH 5.99, 6.38, 6.78, 7.10, 7.40, 7.69, 8.15, 8.45, and 8.83, ${\Delta}$Ao-${\Delta}$At was significantly increased at pH7.69 to 8.83, and ${\Delta}$Ao-${\Delta}$At in 1st sperm washed solution was significantly higher than that in 2nd and 3rd sperm washed solution. 3. When sperm of Holstein, KNC and Hereford was thrice washed with SHP solutions of pH 5.99, 6.38, 6.78, 7.10, 7.40, 7.69, 8.15, 8.45, and 8.83, Holstein showed higher ${\Delta}$Ao-${\Delta}$At of sperm Washed solution than KNC and Hereford, and ${\Delta}$Ao-${\Delta}$At in sperm washed solution was significantly increased at 7.69 for Holstein and at 8.15 for KNC and Hereford, respectively. 4. When sperm was thrice with SHP solution of pH 6.8, 7.1 and 7.4, and then incubated in mTALP of pH 7.4 for 15 minutes, in 1st and 2nd sperm washing ${\Delta}$Ao-${\Delta}$At of sperm washed solution was significantly higher at pH 7.1 and 7.4 than at pH 6.8, and the sperm acrosome reaction of pH 6.8, 7.1 and 7.4 was 49.1, 68.8 and 72.9%, respectively. The sperm acrosome reaction of pH 7.1 and 7.4 was higher than that of pH 6.8.