• Environmental Engineering Research
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• 제20권4호
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• pp.342-346
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• 2015

Haloacetonitriles (HANs) are nitrogenous disinfection by-products (DBPs) that have been reported to have a higher toxicity than the other groups of DBPs. The adsorption process is mostly used to remove HANs in aqueous solutions. Functionalized composite materials tend to be effective adsorbents due to their hydrophobicity and specific adsorptive mechanism. In this study, the removal of dichloroacetonitrile (DCAN) from tap water by adsorption on thiol-functionalized mesoporous composites made from natural rubber (NR) and hexagonal mesoporous silica (HMS-SH) was investigated. Fourier-transform infrared spectroscopy (FTIR) results revealed that the thiol group of NR/HMS was covered with NR molecules. X-ray diffraction (XRD) analysis indicated an expansion of the hexagonal unit cell. Adsorption kinetic and isotherm models were used to determine the adsorption mechanisms and the experiments revealed that NR/HMS-SH had a higher DCAN adsorption capacity than powered activated carbon (PAC). NR/HMS-SH adsorption reached equilibrium after 12 hours and its adsorption kinetics fit well with a pseudo-second-order model. A linear model was found to fit well with the DCAN adsorption isotherm at a low concentration level.

• 한국환경보건학회지
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• 제24권3호
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• pp.26-34
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• 1998

Diethanolamine Dithiocarbamate containing OH groups which gave water-soluble [Pt(dtc)$_{2}$] (diethanolamine dithiocarbamate) were synthesized from the reaction of CS$_{2}$ with diethanolamine. The complex has been characterized by elemental analysis, electrical conductivity, and spectroscopic results. Diethanolamine dithiocarbamate is effective as rescue and inhibition of cis-[$Pt(NH_{3})_{2}Cl_{2}$] nephrotoxicity in rats. It is suggested that diethanolamine dithiocarbamare removes platinum(II) complex coordinated to -SH groups of protein of kidney tubule cells.

• 한국가축번식학회지
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• 제22권4호
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• pp.385-393
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• 1998

본 연구는 돼지 미성숙 난포란을 체외에서 성숙시킬 때, cysteine (CySH) 및 glutathione (GSH) 의 첨가 배양이 난핵포붕괴 및 핵성숙율에 미치는 영향을 조사하기 위하여 실시하였다. 본 연구에서 얻은 결과를 요약하면 다음과 같다. 1. 체외성숙 배양액인 TCM-199 에 cysteine (CySH) 을 각각 0, 0.04, 0.14, 0.6 및 1.2 mM 첨가하여 36 시간 동안 체외성숙을 유기시켰을 때의 난핵포붕괴율은 각각 90.8, 89.9, 90.5, 92.0 및 91.3% 으로서 각 처리구간 유의성이 없었고, 핵성숙율은 각각 56.1, 50.7, 41.9, 49.0 및 61.5%로서 대조구에 비하여 낮은 성숙율을 보였으며, 특히 0.14 mM 및 0.6 mM 첨가군에서 유의적으로 낮은 결과를 보였다 (P＜0.05). 또한, 44시간 동안 체외성숙을 유기시켰을 때 난핵포붕괴율은 각각 90.0, 91.8, 89.8, 90.5 및 89.6%로서 처리구간 유의성이 없었고, 핵성숙율은 각각 80.2, 76.3, 69.4, 66.7 및 72.6%로서 무첨가한 대조구에 비하여 비교적 낮은 성숙율을 보였으며, 특히 0.14 mM 및 0.6 mM 첨가군에서 유의적으로 낮은 결과를 보였다 (P＜0.05). 2. 체외성숙 배양액인 TCM-199 에 glutathione (GSH) 을 0, 0.05, 0.1, 0.5 및 1.0 mM 을 첨가하여 36시간 동안 성숙을 유기시켰을 때 난핵포 붕괴율은 각각 91.0, 90.9, 89.5, 92.0 및 91.1%로서 처리구간 유의성이 없이 높은 결과를 나타냈으며, 핵성숙율은 59.0, 48.5, 47.8, 38.6 및 37.5%로서 대조구에 비하여 모든 처리구에서 유의적으로 낮은 결과를 나타냈다 (P＜0.05). 또한, 44시간 동안 성숙을 유기시켰을 때 난핵포붕괴율은 각각 91.8, 94.1, 89.1, 91.3 및 91.1%로서 모든 처리구에서 높은 결과를 나타냈으며, 핵성숙율은 각각 84.6, 57.1, 69.6, 71.3 및 64.3%로서 대조구에 비하여 모든 처리구에서 유의적으로 낮은 결과를 나타냈다 (P＜0.05).

• Food Science and Biotechnology
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• 제16권3호
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• pp.404-408
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• 2007

In this study, we investigated the effects by age of long-tenn supplementation of Epimedium koreanum Nakai (EKN)-containing water on the in vivo antioxidant capacities of rats. All rats were reared in a conventional system, and none of the rats showed any signs of aversion to the EKN solution. Neither the mean nor maximum life spans of the rats were extended by long-tenn administration of the solution. The EKN extract caused decreases in the levels of serum thiobarbituric acid reactive substances in the rats. The activities of superoxide dismutase, catalase, and glutathione (GSH) peroxidase within the liver cytosol decreased with age in both the control and EKN-supplemented groups. GSH peroxidase activity, however, was higher at old age in the EKN-supplemented group. The activities of GSH reductase and GSH-S-transferase, and the levels of free-sulfhydryl (SH) and total-SH group gradually decreased with age in both groups. However, there was some tendency for higher levels in the EKN supplemented group at a corresponding age. These results indicate that long-tenn supplementation of EKN water extracts alone does not exhibit discernible adverse effects in rats, and has some enhancing effects on the antioxidant capacities of the blood and liver, but it does not have life-prolonging effects.

• 동의생리병리학회지
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• 제26권3호
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• pp.360-366
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• 2012

There have been many studies to find out association between the face characteristics and some diseases or the personality and the health state, but there have been few association studies between the face characteristics and the yin/yang personality. We would like to suggest that the yin/yang personality is associated with the face characteristics. We collected 1,471 subjects from the February, 2008 to July, 2010. We divided into three groups of subjects by a yin/yang personality score and analyzed the face characteristics after adjusting for age. The Analysis of Covariance and Scheffe test was conducted to certify the difference among three groups. P-value for significance was under 0.05. The significant face characteristics were SH36 in men, and FD50_51, SH36, FArea04, FAreaRatio4, FR01, FR05 in women. There is some association between the face characteristics and the yin/yang personality.

• Archives of Pharmacal Research
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• 제28권4호
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• pp.438-442
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• 2005

A series of 3-[1-(4-(2-methylpropyl) phenyl) ethyl]-1,2,4-triazole-5-thione (I) and its bicyclic condensed derivatives 6-benzylidenethiazolo[3,2-b]-1, 2,4-triazole-5(6H)-ones (IIa-IIf) were investigated for the prevention of ethanol-induced oxidative stress in liver and brain of mice. Administration of ethanol (0.1 mL/mice, p.o.) resulted in a drop of total thiol groups (T-SH) and non-protein thiol groups (NP-SH), and an increase in thiobarbituric acid reactive substances (TBARS) in both liver and brain tissue of mice (p<0.001). Among the compounds investigated (at a dose of 200 mg/kg, p.o.), I and IId ameliorated the peroxidative injury in these tissues effectively. Compounds IIa, IIc and IIe improved the peroxidative tissue injury only in brain. These findings suggest that certain condensed thiazolo-triazole compounds may contribute to the control of ethanol-induced oxidative stress in an organ selective manner.

• 대한한방내과학회지
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• 제26권2호
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• pp.379-389
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• 2005

Objectives: It is well known that aging and aging-related diseases are linked to the increased level of oxidative stress caused by reactive oxygen species(ROS) and reactive nitrogen species(RNS). Nonprotein-SH decreases during aging, while substances such as ROS, nitric oxide(NO), peroxynitrite($ONOO^-$), myeloperoxidase(MPO), and dityrosine show a significant increase. This study investigated the effect of Ichungwhan on the aging process by examining its effect on the generation of the above-mentioned substances. Methods: Four comparison groups of SD rats were used. They were 6 month-old rats, 24 month-old rats, and 24 month-old rats fed with food containing 0.1% and 0.3% of Ichungwhan extract. The amount of NO, $ONOO^-$, and ROS in the rats' kidneys were examined using a fluorescence microplate reader. The reagents used for this purpose include: dihydrorhodamine 123 (DHR 123), 2',7' -dichlorodihydrofluorescein, diacetate(DCFDA), and 4,5-diaminofluorescein(DAF-2). A spectrophotometer was used to investigate the reactivity of nonprotein-SH and myeioperoxidase(MPO), using reagents such as trichloroacetic acid(TCA) and tetramethylbenzidine(TMB). The amounts of MPO protein and dityrosine were measued by western blot. Results: The observed effects of Ichungwhan on rats were as follows: increase of nonprotein-SH; effective decrease of RNS level by suppression of the generation system of $ONOO^-$ and NO; decrease of ROS level; decrease of the MPO reactivity and the subsequent reduction of amount of MPO protein; retardation of dityrosine formation. It can be hypothesized, therefore, that Ichungwhan affects both the earlier and later phases of the molecular inflammatory process, and retards the aging process. Conclusions: Empirical evidence in this study supports a role for Ichungwhan in generation mechanisms of aging process-linked substances ROS, NO, $ONOO^-$, nonprotein-SH, MPO and dityrosine. Affects contrary to the aging process observed in rats beg further empiricism to investigate potential application of Ichungwhan as a medication for age-related diseases in humans.

• 한국지구과학회지
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• 제22권4호
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• pp.292-300
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• 2001

1997년 12월 이후 남한 중부지역에서 방생한 지진 중 13개 지진에 대하여, 지역에 따라 5개 그룹으로 구분하여 P 파 극성을 이용하여 구한 복합단층면해와 P, S파 극성 및 진폭비(SV/P, SH/P, SV/SH)를 이용하여 구한 결과를 비교 해석하였다. 지진원에서의 단층운동은 NNE-SSW와 WNW-ESE 방향의 단층면을 나타내며 주향이동 혹은 역단층성 주향이동운동이 우세하게 나타났다. 단층운동에 작용한 주압축응력방향은 ENE-WSW 방향, 혹은 NE-SW 방향을 나타내며, 이는 남한지역에 발생하는 주요 지진에 대하여 구해진 주압축 응력장 방향과 거의 일치한다.

• Structural Engineering and Mechanics
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• 제41권5호
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• pp.605-615
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• 2012

In this paper, guided circumferential wave propagating in an orthotropic viscoelastic cylindrical curved plate subjected to traction-free conditions is investigated in the frame of the Kelvin-Voight viscoelastic theory. The obtained three wave equations are decoupled into two groups, Lamb-like wave and SH wave. They are separately solved by the Legendre polynomial series approach. The availability of the method is confirmed through the comparison with the published data of the SH wave for a viscoelastic flat plate. The dispersion curves and attenuation curves for the carbon fiber and prepreg cylindrical plates are illustrated and the viscous effect on dispersion curves is shown. The influences of the ratio of radius to thickness are analyzed.

• Asian-Australasian Journal of Animal Sciences
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• 제18권8호
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• pp.1130-1134
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• 2005

An experiment was performed using 20 calves of about one-month old to investigate the effect of chelation therapy with calcium disodium ethylenediaminetetraacetate ($CaNa_2$EDTA) alone or along with antioxidant $\alpha$-tocopherol in lead loaded calves on blood trace minerals, erythrocytic sulfahydryl groups and some haematobiochemical parameters. Fifteen calves were given lead orally at a daily dose of 7.5 mg of 99% pure lead acetate/kg body weight for 28 days. Then the lead was withdrawn on day 28 and the calves were randomly divided into three groups. Each group of five animals was either treated with $CaNa_2$EDTA alone at the dose rate of 110 mg/kg body weight in two divided doses for 4 days or along with $\alpha$-tocopherol at the dose rate of 100 mg/kg body weight orally daily for 7 days, keeping the remaining five calves as lead-exposed untreated controls. Blood samples were collected at the end of the lead exposure (day 0) and thereafter on day 2, 4, 7 and 10 from the start of the chelation treatment. The treatment with EDTA alone led to slow but non-significant improvement in blood copper level, but incorporation of antioxidant $\alpha$-tocopherol in chelation therapy resulted in its significant decline, as recorded on day 7-post treatment. Withdrawal of lead or treatment with $CaNa_2$EDTA alone or along with $\alpha$-tocopherol enhanced the erythrocytic thiol contents and the levels of T-SH and P-SH became statistically (p<0.05) comparable to those of lead-exposed controls by day 7 and 4, respectively. There was no significant (p>0.05) change in serum urea, creatinine, total protein and albumin levels between the treatment groups. It is concluded from the present investigation that treatment with $CaNa_2$EDTA at the present dose rate is safe to be used for chelation in lead loaded calves.