• The Journal of Internal Korean Medicine
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• v.30 no.4
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• pp.880-892
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• 2009

Objectives : This study is about a comparison of controlled and uncontrolled hypertension groups regarding pulse shape and quality of life. We aimed to find out if pulse shape would be able to help with hypertension treatment and care. Methods : We surveyed "controlled and uncontrolled hypertension patients" using SF-36, HTN QoL (measurement scale for the quality of life in hypertensive patients) and 3-D MAC pulse analyzer for pulse shape. Results : The uncontrolled hypertension group tended to have a sink pulse in the left cun. right guan & chi parts compared to the controlled hypertension group. Within the controlled hypertension group, patients who had a float pulse shape in both guan parts had a higher quality of life than patients who had a normal pulse shape. And the patients who had a normal pulse shape in both chi parts had a higher quality of life than patients with a slow or fast pulse shape. Within the uncontrolled hypertension grouP. the patients who had a normal pulse shape in right guan part had a higher quality of life than those with a choppy pulse shape. Nevertheless, these results were limited to only a few quality of life issues and were inconsistent in relation to specific pulse shapes. Conclusion : If we have more samples and better methods for collecting data, we will have better results, allowing us to improve our ability to predict and treat hypertension.

• The Korean Journal of Pain
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• v.21 no.3
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• pp.197-201
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• 2008

Background: Kyphoplasty is a minimally invasive procedure that can stabilize osteoporotic and neoplastic vertebral fractures. We retrospectively evaluated the clinical outcomes of kyphoplasty for the treatment of vertebral compression fractures in cancer patients. Methods: We reviewed the clinical data of 27 cancer patients who were treated with kyphoplasty (55 vertebral bodies) between May 2003 and Feb 2008. The clinical parameters, using a visual analog 10 point scale (VAS) and the mobility scores, as well as consumption of analgesic, were evaluated preoperatively and at 1 week after kyphoplasty. Results: A total 55 cases of thoracic and lumbar kyphoplasties were performed without complications. The mean age of the patients was 66 years. All the patients experienced a significant improvement in their subjective pain and mobility immediately after the procedures. The pain scores (VAS), mobility scores and other functional evaluations using the Oswestry disability score and the SF-36 showed significant differences between the pre- and postoperational conditions. Conclusions: Kyphoplasty is an effective, minimally invasive procedure that can relieve the pain of patients with vertebral compression fractures and these fractures are the result of metastasis.

• The Journal of the Korea Contents Association
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• v.14 no.8
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• pp.266-276
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• 2014

The present study aims to determine the effect of the prevention exercise program of musculoskeletal disorders developed for apple and pear farmers. To achieve this goal, 25 farmers who have subjective symptoms in the musculoskeletal system (Criteria 1 in the National Institute for Occupational Safety and Health) have conducted the prevention exercise program for 12 weeks from April 7, 2011 to July 1, 2011. As a result, the prevention exercise program of the musculoskeletal disorders for farmers in the fruit growing industry have improved physical capability of them (upper extremity endurance, lower extremity endurance, balance and agility) as well as a quality of life effectively. In addition, a quality of life showed a significant correlation with Oswestry Disability Index, and Psychosocial Well-being Index. For the future study, various studies are expected to develop and apply exercise programs in consideration of the characteristics of farming work.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.9
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• pp.5578-5584
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• 2014

In this study, 46 patients from a local hemodialysis center were enrolled to assess the effects of a self-motivated virtual reality (VR) exercise program on the heart rate variability and quality of life control in hemodialysis patients. The VR group (n = 23) completed a VR exercise program, where the subjects performed the exercise 40 min per session, 3 sessions per week, for 8weeks. After the exercise program, the heart rate variability and quality of life were measured. The VR group showed significant improvement in the heart rate variability and quality of life. The self-motivated VR exercise program provided both the role of supervisor as well as feedback, which is important for hemodialysis patients.Therefore, a self-motivated VR exercise program may be a useful tool for improving the psychosocial function in chronic disease patients undergoing hemodialysis.

• Korean Journal of Adult Nursing
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• v.23 no.4
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• pp.332-339
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• 2011

Purpose: The purpose of this study was to compare depression, somatoform disorders, and quality of life among older adults. Methods: Samples of 280 community-dwelling Korean older adults were included. The age range of the participants was 60 to 90 years (average $72.6{\pm}6.4$). The participants were assigned to one of two groups based on reported scores on the Pittsburgh Sleep Quality Index from September 2006 to March 2007. The two groups were designated as "poor sleepers"and "good sleepers". A T-test was used to compare depression, somatoform disorders and quality of life between the two groups. Results: Forty-six percent of participants reported scores that indicated they were poor sleepers. Poor sleepers reported significantly higher depression scores (p<.001), higher somatoform disorders scores (p<.001), lower for each SF-36 quality of life dimension, and lower mental and physical health summary scores (p<.001) than the reported scores of those participants who were classified as good sleepers. Conclusion: Older adults with poor sleep patterns are more likely to report higher depression, more somatoform disorders and a lower quality of life. Additional research is needed to identify the appropriate nursing interventions aimed at improving sleep quality, depression symptoms, somatoform disorders and the quality of life.

• Journal of Microbiology and Biotechnology
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• v.8 no.4
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• pp.369-377
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• 1998

Rotavirus is a major cause of severe gastroenteritis in young children and animals throughout the world. The VP7 of rotavirus is thought to induce the synthesis of neutralizing antibodies and to be responsible for determining viral serotypes. The cDNA coding for the VP7 capsid protein of human rotavirus, obtained from Korean patients (HRV-Y14), was cloned and its nucleotide sequence was determined. Comparative analysis of the nucleotide sequences between VP7 of Y14 and that of other foreign isolates showed $92.7~95.2\%$ homology to G1 serotypes (RV-4, KU, K8, WA), $74.2\%$ homolgy to G2 serotype HU-5, $76.4\%$ homology to G3 serotype SA-11, and $77.6\%$ homology to G4 serotype A01321. These data suggest that HRV-Y14 can be classified as a G1 serotype. cDNA coding for VP7 of HRV-YI4 was subcloned into the baculovirus vector and the VP7 glycoprotein was expressed in insect cells. The expressed proteins in Sf9 cell extract and tissue culture fluid were separated on SDS-PAGE, and Western blot analysis with monoclonal antibody raised against the synthetic peptide containing 21 amino acids within the VP7 conserved region was performed. The molecular weight of recombinant VP7 was estimated to be 36 kDa which is about the same size as the native VP7. Addition of tunicamycin in the culture media caused a reduction of the molecular weight of the recombinant VP7 indicating that the expressed protein was glycosylated.

• Korean Journal of Agricultural Science
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• v.37 no.3
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• pp.535-542
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• 2010

The purpose of this study was to survey and diagnostic the self-related health cognition, stress, culture life and health-related fitness for residents of rural area. For this study, Total 126 people answered by a written questionnaire and took part in health-related fitness test for old adults in rural area. According to the normal distribution, the indexes were divided into five grades(very poor 5, poor 4, average 3, good 2, very good 1). The self-related health cognition(SF-36) was third grades. The index was as same as average old adults in rural area. The old adults stress level was third grades. The degrees of stress were as same as average old adults in rural area. The participation in the culture life was fourth grades. The health-related fitness test were third-fifth grades. The results of this experiment could be functioned as a very important fundamental source in order to establish satisfying health system, social welfare for the old people in rural area. Taken together, it seemed that self-related health cognition, stress level, participation in the culture life and health-related fitness have to be considered and improved. The indexes should be further investigated and some practical method should be developed for the olded people in rural area.

• Child Health Nursing Research
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• v.24 no.1
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• pp.78-90
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• 2018

Purpose: The purpose of this study was to evaluate measurement properties of self-report questionnaires measuring the social adjustment for youth after treatment of childhood cancer. Methods: Social adjustment measurement tools were identified through a two-stage systematic review. First, we searched for articles using self-report questionnaires to measure the social adjustment of youth after the treatment of childhood cancer. The appropriate tools were listed and categorized. Second, using methodological filters, we searched 5 electronic databases for articles examining the measurement properties of the tools when used with youth after the treatment of childhood cancer. The quality of these papers was then evaluated using the COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) checklist. Results: Eight tools were frequently used to measure social adjustment. Eight studies investigated the measurement properties of 4 of these tools. The PedsQL 4.0 and MMQL-AF had moderate to strong evidence in some domains, but the rest of the domains had a lack of evidence. The SF-36 and KIDSCREEN-27 were validated for only a few areas. Conclusion: We found a lack of evidence regarding the measurement properties of these tools. More research is required on the measurement properties of tools for use in this population.

• Korean Journal of Adult Nursing
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• v.16 no.2
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• pp.191-201
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• 2004

Purpose: Many studies have shown that regular exercise produces positive effects on health. The purpose of this study was to examine the differences of health-related quality of life by stage of exercise and the interaction effect of age, sex and stage of exercise. Method: A total of 1266 participants were interviewed with structured questionnaire. Stage of exercise was assessed with a single item and respondents were classified with respect to exercise intention and behavior. Health-related quality of life was measured with SF-36 Health Survey Questionnaire. Result: Health-related QOL were found to be different by stage of exercise. The subjects who were reached maintenance stage showed significantly higher scores on physical functioning, bodily pain, general health perception, mental health, role limitation due to emotional problems, social functioning, and vitality than those in preparation, contemplation, and precontemplation stage. In addition a significant interaction effect between stage of exercise and age was found on physical functioning, bodily pain, general health perception, mental health, and vitality. Conclusion: Perceived health-related QOL varies with stage of exercise. This finding suggests that health is related to both intention and behavior of exercise. Therefore it is important to consider cognitive-motivational and behavioral stage of change for developing exercise programs.

• Journal of Sericultural and Entomological Science
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• v.38 no.1
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• pp.36-41
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• 1996

Recombinant baculoviruses having expanded host range were selected by coinfection of Autographa california NPV and Bombyx mori NPV into Sf-9 and BmN-4 insect cell lines. In order to determine the polyhedra morhplogy of RecS-A6, one of a recombinant baculovirus, polyhedra of RecS-A6 produced in insect cells were observed by phase contrast microscope and scanning electron microscope. The results revealed that the recombinant baculovirus had a various polyhedra morphology which was different from its parental viruses, suggesting that the various morhpology of recombinant baculovirus with an expanded host range was due to the genetic recombination of viral genome. To analyze the genomic recombinantion of the recombinant baculoviruses, genomic DNAs of two parent viruses and RecS-A6 were digested with restriction endonuclease and subjected to agarose gel electrophoresis. Southern blot analysis revealed that RecS-A6 has two polyhedrin gene of AcNPV and BmNPV in a viral genome. Polyhedral protein of recombinant baculovirus was analysed by SDS-PAGE. The result showed that molecular weight of polyhedral protein of RecS-A6 containing two polyhedrin gene of AcNPV and BmNPV was as the 31 kDa band of AcNPV and 30 kDa band of BmNPV.