• 원자력산업
• /
• 제36권11호
• /
• pp.29-44
• /
• 2016

1980~1990년대 OPR1000 기술 자립을 추진할 때도 그랬지만 한국은 원자력 기술 자립에 대한 도전이 선진국에 비해 늦었지만 과학기술자의 열정과 정부의 적극적인 지원으로 오늘날 원자력 선진국이 될 수 있었고, 원자력산업을 해외 수출 산업으로서 다양한 노력을 시도하고 있다. 특히 국내 가동 중인 원전은 외국과 차별되게 1기당 고장 정지율이 0.1건으로 외국 평균의 5.5건과 크게 대별된다. 또한 운전 신뢰성을 나타내는 발전소 가동률도 10% 이상 차로 월등히 높다. 한마디로 한국은 가장 원전의 기술 개발과 운영을 잘하고 있는 원전 선진국임을 자타가 인정하고 있다. 그러나 현재의 기술 수준에 머물면 미래 원전 기술에서는 다른 선진국 내지 중국, 인도 등 신흥국에 그 자리를 양보할 수밖에 없을 것이다. 미래 원자력이란 시대적 요건인 고유 안전성과 지속 가능성을 확보하고 경제성과 함께 핵확산 저항성이 전제되는 원자력 신기술로서 세계와의 경쟁 대상이다. 여기에 핵연료 자원의 유한성에 지속 가능성을 확보하기 위해서 우라늄 효율을 극대화하는 제4세대의 고속로 개발까지 우리나라는 선도적 위치로 가야 한다. 이 기술 개발 역시 출발은 늦었지만 적극적인 개발을 추진하고 있어 소듐고속로의 시현 원자로인 PGSFR을 2028년까지 완성하는 목표를 달성하면, 이를 근간으로 세계 선진국의 경쟁 대열에 나설 수 있다. 정부의 적극적인 지원이 선도적 위치에 갈 수 있는 지름길이다. 고속로 기술 개발과 관련하여 사용후핵연료(SF)의 국가 정책이 아직 확정되지 않아 재활용주기를 전제하고 있는 고속로 개발에 어려움을 주고 있다. 따라서 SF 부지를 2028년까지 확정하는 일정과 함께 국가 SF 정책이 조속히 확정되어야 한다.

• 대한전기학회:학술대회논문집
• /
• 대한전기학회 2006년도 제37회 하계학술대회 논문집 C
• /
• pp.1422-1423
• /
• 2006

In our study, the PTFE nozzle ablation in the high-voltage self-blast type $SF_6$ gas circuit breaker was investigated. The test circuit breaker has the structure that the pin electrode is moving and the pressure reservoir volume and the dimension is almost same as commercial 145kv 40kA circuit breaker for similar result in real circuit breaker. The variation of current and arcing time was the range of $36kA_{rms}$(symmetry) - $40kA_{rms}$(asymmetry) and 10-16 ms. From the measured data the tendecy of the mass loss of the nozzle to current load and arc energy was estimated. In this process, the distance from the arc to nozzle(PTFE) surface, area which was exposed to arc and stroke contour was considered. These results will be used to enhance the accuracy of the computational fluid dynamics analysis in circuit breaker and estimate the residual life time of a circuit breaker.

• 한국자기공명학회논문지
• /
• 제19권1호
• /
• pp.36-41
• /
• 2015

The causative agent of shigellosis, Shigella flexneri, is a Gram-negative anaerobic bacterial pathogen that causes one of the most infectious bacterial dysenteries in humans. It originates infection by invading cells of the colonic epithelium using a type III secretion system. Despite S. flexneri is closely linked with the human disease, structural study is very deficient. Here, we have initiated NMR study of SF1002 which is the uncharacterized protein from S. flexneri strain 5a M90T. Based on a series of triple resonance spectra, sequence-specific assignments of the backbone amide resonances of SF1002 could be completed. This NMR study would contribute to the structural genomics of S.flexneri.

• 한방재활의학과학회지
• /
• 제23권4호
• /
• pp.95-115
• /
• 2013

Objectives The aim of this review is to provide fundamental data for low back pain scales which can be used in clinical trial. Methods We investigated the latest studies on chronic low back pain via PubMed. And we also investigated domestic studies through "http://oasis.kiom.re.kr". 95 research papers were analyzed. Scales were classified into pain scale, function scale, generic health status scale and psychological scale. Results 1) According to foreign clinical studies, Visual Analog Scale (VAS) and Numerical Rating Scale (NRS) were used 18 times as pain scale. Oswestry Disability Index (ODI) was used 20 times as function scale, Roland-Morris Disability Questionnaire (RMDQ) was 17, and Hannover Functional Ability Questionnaire (HFAQ) was used 3 times. 36-item Short Form Health Survey (SF-36) was used 13 times as generic health status scale, Euroqol-5 Dimentions Questionnaire (EQ-5D) was 11, and 12-item Short Form Health Survey (SF-12) was used 3 times. Fear-Avoidance Beliefs Questionnaire (FABQ) was used 9 times as psychological scale, Pain Catastrophizing Scale (PCS) and Tampa Scale for Kinesiophobia (TSK-R) both were used 3 times. 2) According to domestic clinical studies, VAS was used 37 times as pain scale, NRS was 11, and Short Form McGill Pain Questionnaire (SF-MPQ) was used 6 times. ODI was used 30 times as function scale, RMDQ was 2 times only. SF-36 was used once as generic health status scale and Beck's Depression Inventory (BDI) was used 3 times as psychological scale. Conclusions We recommend VAS or NRS as a measure to evaluate pain, and ODI as a measure to evaluate functional disability. And we also recommend SF-36 or SF-12 and EQ-5D as a measure to evaluate generic health status. Finally, we recommend FABQ for use in measuring psychological scale.

• 한국식품영양과학회지
• /
• 제41권11호
• /
• pp.1502-1507
• /
• 2012

맨드라미꽃의 식품학적 이용가능성을 확인해 보고자 항산화성분 및 항산화활성에 대해 검토하였다. 맨드라미꽃의 항산화성분과 활성은 메탄올 추출물과 순차적 용매분획물에 대해 측정하였으며, 메탄올 추출물과 hexane, chloroform, ethyl acetate, butanol 및 물 분획물의 추출수율은 각각 23.33, 10.27, 20.00, 13.63, 17.55 및 38.54%였다. 맨드라미꽃 메탄올 추출물의 총 polyphenol, flavonoid 및 tannin 함량은 각각 6.80 mg GAE/g ME, 2.34 mg CE/g ME 및 6.23 mg TAE/g ME였다. 순차적 용매분획물 중 butanol 분획에서 각각 14.92 mg GAE/g SF, 5.44 mg CE/g SF 및 13.38 mg TAE/g SF로 함량이 높았다. 총 proanthocyanidin 함량은 $44.72{\mu}g$ CE/g ME였고 순차적 용매분획물은 각각 42.47, 44.43, 50.03, 49.12 및 $41.80{\mu}g$ CE/g ER로 용매간 유의적인 차이를 보이지 않았다. 맨드라미꽃의 메탄올 추출물의 DPPH 및 ABTS radical 소거활성은 각각 5.24 및 10.70 mg TE/g ME였고 butanol 분획에서 각각 12.53 및 21.09 mg TE/g SF로 활성이 높았다. 메탄올 추출물의 SOD 유사활성은 7.96 unit/mL로 나타났고 hexane, chloroform, ethyl acetate, butanol 및 물 분획물은 각각 4.56, 6.15, 8.07, 12.36 및 5.21 unit/mL로 butanol 분획의 활성이 높았다. 맨드라미꽃 추출물의 항산화성분과 항산화활성 간에 높은 정의 상관관계를 보였고 맨드라미꽃 추출물이 체내 및 식품에서 유익한 도움을 줄 수 있을 것으로 생각된다.

• 동의생리병리학회지
• /
• 제33권4호
• /
• pp.239-248
• /
• 2019

There are no published data on Gyeongokgo (GOK) safety or efficacy despite being commonly use. The Gyeongokgo (GOK) is commonly used in traditional Korean medicine to promote a health qi and blood, but their objective data was not sufficient in clinical field. To investigate the safety and efficacy of GOK with hematologic and serologic testing and the change of the quality of life in healthy individuals. Randomized, subject-assessor-blind, placebo-controlled, single-center pilot study Participants and Interventions 29 healthy volunteer subjects were randomly placed into the GOK group (n = 20) or placebo control group (n = 9) and instructed to take one treatment packet (GOK or placebo) twice daily for 4 weeks. Subjects were assessed using the Fatigue Severity Scale (FSS) and Short Form 36 Health Survey (SF-36) and underwent hematologic and serologic tests and body composition analysis. The FSS total score (p = 0.093) and SF-36 general health index (p = 0.002) were improved following treatment in the GOK group. Post-treatment thyroid-stimulating hormone levels were increased in the GOK group compared with pre-treatment levels (p = 0.0042). C-reactive protein levels decreased (p = 0.0256) in the GOK group compared with that the placebo group. In time-series tests, GOK did not affect post-prandial serum triglycerides, glucose, insulin, or C-peptide levels. Notably, elevations in serum fasting triglycerides at 2- (p = 0.0333) and 4-hours (p = 0.0414) post-prandial were lower than those in the placebo group. GOK reduced fatigue levels and did not significantly affect laboratory test results performed to measure safety, serum glucose, and lipid profiles. Post-meal triglyceride levels were effectively reduced with treatment.

• 한국산학기술학회논문지
• /
• 제16권1호
• /
• pp.490-497
• /
• 2015

본 연구는 신체적 기능장애를 지닌 국가유공자의 삶의 질 수준을 확인하고 삶의 질에 영향을 미치는 관련 요인들을 알아보기 위하여 실시하였다. 연구대상자는 서울, 부산, 대구, 광주와 대전에 위치한 보훈병원에서 신체적 기능장애로 치료를 받고 있는 국가유공자 412명을 대상으로 하였다. 대상자의 삶의 질은 SF-36을 이용하여 평가하였고, 일상생활동작은 수정된 바델지수로, 통증수준은 4항목 시각적 상사척도로, 우울증 척도는 노인우울척도를 이용하여 평가하였다. 연구 결과, 삶의 질은 연령이 높을수록, 주관적 건강상태가 나쁠수록, 경제수준이 낮을수록, 와병기간이 길수록, 통증수준, 우울증 점수가 높을수록 유의하게 낮아지는 것으로 나타났다. 회귀분석 결과 삶의 질에 가장 크게 영향을 미치는 변수는 우울증(B=-.969)이었으며, 주관적 건강상태(B=-5.098), 일상생활동작 수행(B=.140), 통증수준(B=-.163) 순으로 나타났다. 따라서 본 연구의 결과는 신체적 기능장애를 지닌 국가유공자의 삶의 질 향상을 위해 심리적 접근 뿐 아니라 일상생활동작 수행정도 등 신체적 증상의 완화, 통증감소를 개선시킬 수 있는 의학적 중재 및 프로그램 개발의 기초자료로 활용될 수 있을 것이다.

• Journal of Magnetics
• /
• 제19권2호
• /
• pp.161-169
• /
• 2014

The aim of this study is to investigate the efficacy of pulsed electromagnetic field (PEMF) on the alleviation of lumbar myalgia. This is a randomized, real-sham, double blind pilot study. 38 patients were divided into the PEMF group and the Sham group, each of which was composed of 19 patients (1 patient dropped out in the Sham group) of randomized allocation. The PEMF group was treated by using the PEMF device and the Sham group by using a sham device on the lumbar muscle and acupuncture points, three times a week for a total of two weeks. Evaluations of Visual Analogue Scale for bothersomeness (VASB), Visual Analogue Scale for pain intensity (VASP), Oswestry Disability Index (ODI), 36-Item Short Form Health Survey Instrument (SF-36), EuroQol-5Dimension (EQ-5D), Beck's Depression Inventory (BDI) and Roland-Morris Disability Questionnaire (RMDQ), etc. before and 1 week after treatment were carried out. The primary outcome measure was the VASB, measured 1 week after the end of the pulsed electromagnetic therapy. VASB scores for the PEMF group changed by $-2.06{\pm}2.12$ from the baseline, and that for the Sham group changed by $-0.52{\pm}0.82$ (p < 0.05). VASP scores for the PEMF group were reduced by $-2.10{\pm}2.12$ from the base line, and that for the Sham group was reduced by $-0.53{\pm}1.50$ (p < 0.05). PEMF group showed significant improvements in all VASB, VASP, ODI, SF-36, EQ-5D, BDI and RMDQ scores, while the Sham group showed significant improvements in all scores, except the VASP score. However, the VASB, VASP and RMDQ scores of the PEMF group were much lower than those of the Sham group. The two groups showed no significant difference in ODI, SF-36, EQ-5D and BDI. This study demonstrates the effectiveness of PEMF treatment for alleviating lumbar myalgia.

• 동의생리병리학회지
• /
• 제21권4호
• /
• pp.1034-1038
• /
• 2007

To examine the difference of health-related quality of life (QoL) of obese patients between before and after treatment of Korean traditional medicine. This study was assessed in 18 obese-women (age 29.72${\pm}$7.38) treated by acupuncture and herbal medicine using SF-36 quality of life questionnaire between January and July 2006, a 36 item instrument yielding 8 dimensions (Social functioning, Role limitation-Physical, Role limitation-Emotion, Mental health, Vitality, Bodily pain, and General health) and a total score. Their weight was measured by Inbody 3.0 (Biospace co. Korea). QoL and body composition was assessed twice at baseline (B) and 4 weeks after treatment. Auricular acupuncture and electrical needle stimulation to abdomen, thigh, and arm fat was used twice a week and complex herb formula was prescribed according to their constitution and symptoms for 4 weeks. Herb medication was taken 2 times a day. Respective variables were analyzed with Wilcoxon signed ranks test and the level set for statistical significance was p <0.05. The mean of the body weight (P=0.000;B64,68${\pm}$6.86, 4 WKs 60.47${\pm}$5.69), fat percentage (P=0.000;B33.14${\pm}$4.86, 4 WKs 30.16${\pm}$5.34), body mass index (P=0.000;B25.18${\pm}$2.44, 4 WKs 23.46${\pm}$2.09) and fat weight (P=0.000;B21.66${\pm}$5.06, 4 WKs 18.41${\pm}$4.57) of some obese patients decreased significantly between before and after treatment for 4 weeks. Physical functioning (P=0.48;B27.06${\pm}$3.17, 4 WKs 28.00${\pm}$1.71), Mental health (P=0.01 ;B18.83${\pm}$5.25, 4 WKs 22.00${\pm}$3.73), Vitality (P=0.028;B13.89${\pm}$3.03, 4 WKs 15.44${\pm}$2.53), Bodily pain (P=.0014;B8.84${\pm}$1.75, 4 WKs 10.15${\pm}$1.78), and the total scores (P=0.001;B104.99${\pm}$12.60, 4 WKs 114.58${\pm}$11.11) of SF-36 were increased significantly after treatments. These data show some differences in QoL and BMI between before and after treatment on obesity and suggest that the treatment with acupuncture and herbal medicine have a positive impact on several domains of QoL of some obese patients. Further randomized clinical trials (RCTs) including follow-up are needed to examine whether acupuncture and herb medicine have a positive effect on QoL of treatment group compared with control group.

• 한국엔터테인먼트산업학회논문지
• /
• 제14권6호
• /
• pp.301-309
• /
• 2020

본 연구는 4주간 테이핑을 병행한 스위스 볼 운동이 임신성 요통환자의 통증과 기능장애 및 삶의 질에 미치는 효과를 규명하기 위하여 실시되었다. 단일 맹검 및 사전 무작위 임상시험으로 진행되었으며, 16명의 임신성 요통 환자는 무작위로 테이핑과 스위스 볼 운동군(n=8)과 테이핑과 신장 운동군(n=8)으로 배정되었다. 모든 대상자는 허리에 테이핑을 적용하였다. 추가적으로 테이핑과 스위스 볼 운동군은 스위스 볼 운동을 하루 30분, 주 5회, 4주간 시행하였고 테이핑과 신장 운동군은 같은 시간동안 스트레칭 운동을 적용하였다. 통증은 시각사상척도(VAS)를 사용하여 측정하였고, 기능장애는 Roland Morris Disability Questionnaire (RMDQ), 삶의 질은 Short-Form 36 items (SF-36)을 사용하였다. 훈련 후 테이핑과 스위스 볼 운동군이 테이핑과 신장 운동군에 비해 통증과 기능장애, 삶의 질이 유의하게 개선되었다(p<.05). 본 연구는 테이핑을 병행한 스위스 볼운동이 임산부의 요통과 기능장애 및 삶의 질을 효과적으로 향상시킴을 증명하였다.