• Analytical Science and Technology
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• v.13 no.3
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• pp.378-384
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• 2000

This Study has been carried out to develop a method of analysis of 8 permitted synthetic food colors [including Brilliant Blue FCF(B1), Indigocarmine (B2), Fast green FCF(G3), Amaranth (R2), Erythrosine (R3), Allura red (R40), Tartrazine (Y4), Sunset Yellow FCF (Y5)] in Korean foods by HPLC. After adjusting to 0.5% HCl, each of the food colors extracted was eluted by Sep-pak $C_{18}$ cartridge. Eluates were then determined by high performance liquid chromatograph with a UV-VIS detector. Recoveries of the 8 synthetic food colors were found to be 81.2-98.0% for soft drinks, 80.6-96.1% for candy, 79.8-96.3% for chewing gum, 76.5-91.7% for cereals, 79.9-93.8% for ice cream and 78.6-94.7% for jelly, respectively. The detection limits were $0.05-0.1{\mu}g/g$.

• YAKHAK HOEJI
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• v.47 no.5
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• pp.261-265
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• 2003

Near-infrared (NIR) system was used to determine rapidly and simply indomethacin in buffer solution for a dissolution test of tablets and capsules. Indomethacin standards were prepared ranging from 10 to 50 ppm using the mixture of phosphate buffer (pH 7.2) and water (1 : 4). The near-infrared (NIR) transmittance spectra of indomethacin standard solutions were collected by using a quartz cell in 1 mm and 2 mm pathlength. Partial least square regression (PLSR) was explored to develop calibration models over the spectral range 1100∼1700 nm. The model using 1 mm quartz cell was better than that using 2 mm quartz cell. The PLSR models developed gave standard error of prediction (SEP) of 0.858 ppm. In order to validate the developed calibration model, routine analysis was performed using another standard solutions. The NIR routine analysis showed good correlation with actual values. Standard error of prediction (SEP) is 1.414 ppm for 7 indomethacin samples in routine analysis and its error was permeable in the regulation of Korean Pharmacopoeia (VII). These results show the potential use of the real time monitoring for indomethacin during a dissolution test.

• The Bulletin of The Korean Astronomical Society
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• v.43 no.1
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• pp.52.1-52.1
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• 2018

We investigate initial Fe/O enhancements for 44 large gradual solar energetic particles events from 2010 to 2014 and examine the associations of the Fe/O enhancements with the structures of the heliospheric current sheet (HCS). For this study, we use STEREO SIT Fe and O data in 0.32-0.45 MeV channel as well as ACE ULEIS Fe and O data in 0.32-0.64 MeV channel. We determine 1) the magnetic polarities of the SEP source regions using the potential field source surface (PFSS) model of the coronal field and 2) the spacecraft magnetic footpoints with Parker spiral approximation of interplanetary magnetic field using the in-situ measurements of STEREO and ACE. We find that 29 out of 44 events have initial Fe/O enhanced more than 5 times of the typical gradual event values. In the 6 events, the enhancements are simultaneously observed by two spacecraft. There is a tendency that the high Fe/O enhancements are observed near SEP source regions. It is also noted that the Fe/O enhancements are associated with the polarity of the magnetic footpoints. The high Fe/O enhancements are usually observed where their footpoints lie in the same polarity regions of SEP sources rather than the opposite polarity regions. Although Fe/O enhancements could be due to a transport effect and/or a flare contribution, our result implies that the structure of HCS is likely to affect particle propagations in the interplanetary space.

• Analytical Science and Technology
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• v.9 no.2
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• pp.123-133
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• 1996

The optimum conditions for the analysis of the difenoconazole fungicide on soil and crops were investigated and the residues of that in apple and soil were identified by using the gas chromatography. The extract with acetonitrile was separated with saturated NaCl and n-hexane solution after filtered, and concentrated. Obtained fungicide residues were transfered to the florisil column and eluted with acetone and n-hexane mixed solution for the analysis by GLC(ECD). From the standard addition experiments with 0.20 and 1.0ppm, the average recoveries were 86~92% and the detection limit was 0.01 ppm. It seems to be safely used when difenoconazole is treated three times until 15 days before harvest of apple. In this case residual amounts of difenoconazole in apple was from 0.037ppm to 0.044ppm. The soil samples extracted with methanol and ammonium hydroxide mixed solution were partitioned with dichloromethane and saturated sodium chloride solution. The organic phase was concentrated and redissolved with toluene and analyzed with GLC(FID) after cleaned with Sep-Pak column. From the standard addition experiments with 0.10, 0.50 and 1.0ppm, the average recoveries were 101.2~103.7% and the detection limit was 0.025ppm.

• Preventive Nutrition and Food Science
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• v.7 no.1
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• pp.12-17
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• 2002

Simultaneous determination of nine water-soluble vitamins contained in multi-nutrient tablets was carried out by reversed phase high-performance liquid chromatography (RP-HPLC) equipped with analytical $C_{18}$ column and UV (270 nm) detector. Those standard vitamins were successfully separated within 23 minutes by gradient elution with solvent A (0.5 M potassium phosphate monobasic) and solvent B (0.25 M potassium phosphate monobasic-methanol, 1:1). Calibration curves showed good linealities with correlation coefficients (> 0.92) in tested ranged respectively. The detection limits were considered to be 2.1 ng for ascorbic acids 60 ng for Vit B$_{6}$ 3 ng for p-aminobenzoic acid, 9 ng for niacinamide, 9 ng for thiamin, 5.0 ng for folic acid and 1.5 ng for riboflavin at 0.05 a.u.f.s. Solid phase extraction through Sep-Pak (C$_{18}$ ) cartridge was successfully applied for purification of water soluble vitamins in commercial multi-nutrient tablets.ts.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.37
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• pp.13.1-13.7
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• 2015

Background: This study evaluated Somatosensory evoked potentials (SEP), Quantitative sensory testing (QST), and thermography as diagnostic methods for nerve injury. Methods: From 2006 through 2011, 17 patients (mean age: 50.1 years) from ${\bigcirc}{\bigcirc}{\bigcirc}{\bigcirc}$ Hospital who sought care for altered sensation after dental implant treatment were identified. The mean time of objective assessment was 15.2 months after onset. Results: SEP of Inferior alveolar nerve(IAN) was $15.87{\pm}0.87ms$ on the normal side and $16.18{\pm}0.73ms$ on the abnormal side. There was delayed N20 latency on the abnormal side, but the difference was not statistically significant. In QST, the abnormal side showed significantly higher scores of the current perception threshold at 2 KHz, 250 Hz, and 5 Hz. The absolute temperature difference was $0.55^{\circ}C$ without statistically significance. Conclusion: These results indicate that QST is valuable as an objective method for assessment of nerve injury.

• Journal of the Korean Chemical Society
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• v.35 no.6
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• pp.720-724
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• 1991

Simultaneous determination of chloragenic acid (CA), 3,4-o-dicafeoyl quinic acid(3,4-DCQA), 4,5-o-dicaffeoyl quinic acid (4,5-DCQA) and linarin in Chrysanthemum sibiricum Fisher was newly established by a reversed-phase high performance liquid chromatography (HPLC). Sample was extracted with 20 ml methanol for 4 hrs. The extract was cleaned up by using Sep-Pak $C_18$ cartridge and 4 ml methanol-$H_2$O(1 : 1) as eluent. Their determination was performed by means of RP-HPLC with Bondapak $C_18$ column (30 cm ${\times}$ 3.9 mm i.d., 10 ${\mu}m$ and gradient elution mode as methanol-5 mM $H_3PO_4$ solution (30 : 70). The established method was applied to various samples purchased. As a result, their content ranges showed to be 0.35~0.55% for CA, 0.46~0.76% for 3,5-DCQA, 0.077~0.23% for 4,5-DCQA and 0.16~2.72% for linarin, respectively.

• Korean Journal of Occupational Health Nursing
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• v.10 no.1
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• pp.66-73
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• 2001

In health promotion program, the fear of gaining weight is often given as a reason for giving up smoking cessation by the participants. The purpose of this study is to compare drinking habit, exercise and BMI distribution according to smoking habits. The subjects of this study were 83 industrial workers in Gu-mi. Data collection was conducted from Sep. 18th to Sep. 24th 2000. The method was self-reported questionnaire survey, consisted of general characterisics, smoking habits and its relevant questions. The results are as follows : 1. Fifty-nine percents of the subjects were currently smoking. 2. Smoking habits were significantly related with drinking(p=.049). More smokers(81.6%) reported drinking habit than non-smokers(61.7%). 3. Forty-one point two percents of the non-smoker and 34.7% of the smoker perceived their body type as "fat". 4. The mean values of BMI were 22.0 in smokers with 1-9 cigarettes/day, 24.2 in 10-19 cigarettes/day smokers and 24.0 in smokers with over 20 cigarettes/day. There are no statistically significant differences in BMI among smoking habits. 5. BMI among different smoking habit groups was not significant different in age, drinking habit, exercise, and smoking habit.

• Journal of Navigation and Port Research
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• v.28 no.8
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• pp.745-751
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• 2004

Following a preceding study of Shin et al.(2004), wave fields for a month of September of 2003 are simulated based on the modified WAM cycle 4 model that enables the precise wave hindcasting with fine spatial meshes, and characteristics of extreme waves at the south coast of Korea are analyzed The accuracy of applied wave model is verified by comparing computed wave parameters and corresponding ones measured at Ieodo ocean research station. The wave hindcasting of typhoon 'Maemi' with an hour time interval reveals the extreme wave characteristics at 4 primary locations of south coast of Korea as follows: 1) At the front sea of Chaguido in the south of Jeju-do, the maximum significant wave height, mean wave period and mean wave direction appear to be 7.41m, 13.65s and $6.4^{\circ}$ respectively at 16:00 KST of Sep. 12, 2003. 2) At the entrance of Masan Bay, 12.50m, 13.65s and $1.2^{\circ}$ at 21:00 KST of Sep. 12. 3) At the front sea of Suyoung Bay, 13.85m, 13.81s and $0.2^{\circ}$ at 22;00 KST of Sep. 12. 4) At the front sea of Ulsan port, l1.00m, 13.25s and $2.8^{\circ}$ at 23:00 KST of Sep. 12.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2004.11a
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• pp.219-225
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• 2004

Following a preceding study if Shin et al.(2004), wave fields for a month if September if 2003 are simulated based on the modified WAM cycle 4 model that enables the precise wave hindcasting with fine spatial meshes, and characteristics of extreme waves at the south roast if Koreo are analyzed The accuracy if applied wave model is verified by comparing computed wave parameters and corresponding ones measured at Ieodo ocean research station. The wave hindasting if typhoon 'Maemi' with an hour time interval reveals the extreme wave characteristics at 4 primary locations if south coast of Korea as follows: 1) At the front sea of Chaguido in the south of Jeju-do, the maximum significant wave height, moon wave period and mean wave direction appear to be 7.41m, 13.65s and $6.4^{\circ}$, respectively at 16:00 KST if Sep. 12, 2003. 2) At the entrance of Masan Bay, 12.50m, 13.65s and $1.2^{\circ}$ at 21:00 KST if Sep. 12. 3) At the front sea of Suyoung Bay, 13.85m, 13.81s and $0.2^{\circ}$ at 22;00 KST if Sep. 12. 4) At the front sea of Ulsan port, 11.00m, 13.25s and $28^{\circ}$ at 23:00 KST if Sep.