• 제목/요약/키워드: SCTS

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Operational Concept of the NEXTSat-1 for Science Mission and Space Core Technology Verification

  • Shin, Goo-Hwan;Chae, Jang-Soo;Lee, Sang-Hyun;Min, Kyung-Wook;Sohn, Jong-Dae;Jeong, Woong-Seob;Moon, Bong-Gon
    • Journal of Astronomy and Space Sciences
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    • v.31 no.1
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    • pp.67-72
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    • 2014
  • The next generation small satellite-1 (NEXTSat-1) program has been kicked off in 2012, and it will be launched in 2016 for the science missions and the verification of space core technologies. The payloads for these science missions are the Instrument for the Study of Space Storms (ISSS) and NIR Imaging Spectrometer for Star formation history (NISS). The ISSS and the NISS have been developed by Korea Advanced Institute of Science and Technology (KAIST) and Korea Astronomy and Space science Institute (KASI) respectively. The ISSS detects plasma densities and particle fluxes of 10 MeV energy range near the Earth and the NISS uses spectrometer. In order to verify the spacecraft core technologies in the space, the total of 7 space core technologies (SCT) will be applied to the NEXTSat-1 for space verification and those are under development. Thus, the operation modes for the ISSS and the NISS for space science missions and 7 SCTs for technology missions are analyzed for the required operation time during the NEXTSat-1's mission life time of 2 years. In this paper, the operational concept of the NEXTSat-1's science missions as well as the verification of space core technologies are presented considering constraints of volume, mass, and power after launch.

Unrelated stem cell transplantation after reduced-intensity conditioning plus rituximab for Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis with CNS involvement (저강도 전처치와 rituximab 후 타인 조혈모세포 이식을 시행한 중추신경계를 침범한 Epstein-Barr 바이러스 관련 혈구포식 림프조직구증)

  • Baek, Hee Jo;Kook, Hoon;Han, Dong Kyun;Lee, Min-Cheol;Jeong, Tae Woong;Hwang, Tai Ju
    • Clinical and Experimental Pediatrics
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    • v.52 no.6
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    • pp.725-729
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    • 2009
  • Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis (EBV-HLH) with central nervous system (CNS) involvement is usually fatal unless stem cell transplant (SCT) is offered. However, SCT with conventional intensity conditioning is associated with high transplant-related mortality. We describe our experience with unrelated SCTs after reduced-intensity conditioning (RIC) for patients with EBV-HLH with progressive CNS disease. This approach was associated with minimal toxicities and might be an effective option in patients with EBV-HLH with progressive CNS disease. Moreover, the addition of rituximab to RIC appears to be safe and effective in suppressing EBV in the patients with EBV-HLH.

The Differences of Interpersonal Experiences between Multicultural and Korean Children with PTSD Symptoms (심리적 외상 경험 다문화가정 아동과 일반가정 아동이 인식하는 대인관계 특성 비교)

  • Gao, Hong-Yue;Hwang, Mae-Hyang
    • The Korean Journal of Elementary Counseling
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    • v.11 no.2
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    • pp.279-298
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    • 2012
  • The purpose of this study was to explore the different perceptions of relationship with significant others of multicultural children with PTSD symptoms. To select the subjects for this study, Korean version of Greenwald and Rubin's CROPS(Child Report of Post-traumatic Symptoms) was administered to 97 multicultural children and 110 Korean children. Among them 20 multicultural children and 22 Korean children were determined as children with PTSD symptoms. SCT was administrated to 42 children and the content analysis of 42 SCTs was undertaken. The following results are the major findings of this research: a) multicultural children perceived their mothers, fathers, friends, and teachers more negatively than Korean children; b) only 55% of multicultural children had positive self-images while almost Korean children had positive self-images; c) multicultural children expressed psychological trauma from peers in school while Korean children expressed psychological trauma from parents at home. Lastly, we discussed implications of the results, limitations and suggestions for future study.

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Facial palsy as the presenting symptom of acute myeloid leukemia in children: Three cases with stem cell transplantations (안면마비로 초기 발현된 소아 급성골수성백혈병: 조혈모세포이식으로 성공적으로 치료한 3예)

  • Baek, Hee Jo;Han, Dong Kyun;Kim, Young Ok;Choi, Ic Sun;Hwang, Tai Ju;Kook, Hoon
    • Clinical and Experimental Pediatrics
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    • v.52 no.6
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    • pp.713-716
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    • 2009
  • Facial palsy as the presenting symptom of leukemia is very rare, especially in acute myeloid leukemia. A review of the medical literature identified reports on 8 children with AML who had facial paralysis as the presenting sign. Whole brain irradiation (WBI) has been applied in most cases. We present the cases of 3 such children. Achieving a remission without WBI, the patients underwent stem cell transplantations (SCTs). Two patients remain event-free 52 months and 62 months after allotransplants. Facial palsy was the harbinger of leukemic relapse in one case after autotransplant. This patient is disease-free 59 months after unrelated SCT rescue. Facial palsy persisted in 2 cases. Allogeneic SCT without WBI may be an effective therapy in patients presenting with facial palsy. A brief review of the literature is presented here.

Long-term follow-up of Fanconi anemia: clinical manifestation and treatment outcome

  • Yoon, Byung Gyu;Kim, Hee Na;Han, Ui Joung;Jang, Hae In;Han, Dong Kyun;Baek, Hee Jo;Hwang, Tai Ju;Kook, Hoon
    • Clinical and Experimental Pediatrics
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    • v.57 no.3
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    • pp.125-134
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    • 2014
  • Purpose: The aim of this study was to characterize Korean patients with Fanconi anemia (FA), which is a rare but very challenging genetic disease. Methods: The medical records of 12 FA patients diagnosed at Chonnam National University Hospital from 1991 to 2012 were retrospectively reviewed. Results: The median age at diagnosis was 6.2 years. All patients showed evidence of marrow failure and one or more physical stigmata. Chromosome breakage tests were positive in 9 out of 11 available patients. The median follow-up duration was 69.5 months. The Kaplan-Meier (KM) survival of all patients was 83.3% at 10 years and 34.7% at 20 years, respectively. Seven patients underwent 9 stem cell transplantations (SCTs). Among them, 5 were alive by the end of the study. Ten-year KM survival after SCT was 71.4% with a median follow-up of 3.4 years. All 5 patients treated with supportive treatment alone died of infection or progression at the median age of 13.5 years, except for one with short followup duration. Acute leukemia developed in 2 patients at 15.4 and 18.1 years of age. Among 6 patients who are still alive, 3 had short stature and 1 developed insulin-dependent diabetes mellitus. Conclusion: We provide information on the long-term outcomes of FA patients in Korea. A nation-wide FA registry that includes information of the genotypes of Korean patients is required to further characterize ethnic differences and provide the best standard of care for FA patients.