• Title/Summary/Keyword: SCH

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A Case of Adult onset Henoch-Sch$\ddot{o}$nlein Purpura with Acute Renal Failure (급성 신부전을 동반한 성인 Henoch-Sch$\ddot{o}$nlein 자반증 1예)

  • Kim, Seok-Min;Chang, Kyung-Ae;Jung, Sun-Young;Park, Chan-Soh;Park, Jong-Won;Do, Jun-Young;Kim, Yong-Jin;Yoon, Kyung-Woo
    • Journal of Yeungnam Medical Science
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    • v.25 no.1
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    • pp.58-63
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    • 2008
  • Henoch-Sch$\ddot{o}$nlein purpura (HSP) is a leukocytoclastic vasculitis of small vessels with deposition of IgA, commonly resulting in skin, joint, gastrointestinal, and kidney involvement. HSP is an uncommon disorder in adults and accounts for 0.6% to 2% of adult nephropathy. We report a case of HSP with acute renal failure successfully treated with corticosteroid. In this case, the patient presented with vasculitic purpuric rash on lower extremity, arthralgia in the wrist, abdominal pain, hematochezia, oliguria and azotemia. Abdominal CT showed wall thickening of the small and large bowels. Skin biopsy revealed leukocytoclastic vasculitis. Percutaneous renal biopsy showed no crescent formation, but mesangial IgA and $C_3$ deposits were observed by immunofluorescence. The patient was treated with corticosteroid (1mg/kg per day) and hemodialysis. After treatment, renal function improved and purpuric lesion, arthralgia and abdominal pain disappeared. Thus, when adults present with purpuric rash and rapidly progressive glomerulonephritis (RPGN), HSP should be a diagnostic consideration.

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Hypokalemia-induced Polyuria with Nocturia after Intravenous Methylprednisolone Pulse Therapy in a Henoch-Sch$\ddot{o}$nlein Purpura Nephritis Patient (Henoch-Sch$\ddot{o}$nlein Purpura 신염 환자에서 경정맥 고용량 스테로이드 충격요법 후 발생된 저칼륨혈증으로 인한 다뇨증과 야간뇨)

  • Kim, Geun-Jung;Lee, Jun-Ho
    • Childhood Kidney Diseases
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    • v.14 no.2
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    • pp.230-235
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    • 2010
  • Patients with moderate to severe degrees of Henoch-Sch$\ddot{o}$nlein purpura (HSP) nephritis receive high-dose intravenous methylprednisolone pulse therapy (IMPT). Although the regimen is generally safe and effective, various complications occasionally develop. administration of excessive corticosteroid can induce urinary potassium wasting leading to hypokalemia. Polyuria, one of the complications of hypokalemia, is related to both increased thirst and mild nephrogenic diabetes insipidus. And hypokalemia itself also impairs the maximal renal urinary concentration ability. Although polyuria or nocturia after IMPT is not common, it is correctable immediately by oral potassium supplementation. Therefore, during IMPT, careful history taking of nocturia as well as monitoring urine volume, serum and urine potassium level at regular follow-up are necessary because even mild hypokalemia can provoke urine concentrating ability defect. We experienced a case of 11 year-old boy with HSP nephritis who suffered from hypokalemia-induced polyuria with nocturia right after IMPT.

A dynamic analysis on minute particles' detachment mechanism in a cryogenic $CO_2$ cleaning process (극저온 $CO_2$ 세정과정 시 미세오염물의 탈착 메커니즘 연구)

  • Seok, Jong-Won;Lee, Seong-Hoon;Kim, Pil-Kee;Lee, Ju-Hong
    • Journal of the Semiconductor & Display Technology
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    • v.7 no.4
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    • pp.29-33
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    • 2008
  • Rapid increase of integrity for recent semiconductor industry highly demands the development of removal technology of contaminated particles in the scale of a few microns or even smaller. It is known that the surface cleaning technology using $CO_2$ snow has its own merits of high efficiency. However, the detailed removal mechanism of particles using this technology is not yet fully understood due to the lack of sophisticated research endeavors. The detachment mechanism of particles from the substrates is known to be belonged in four types; rebounding, sliding, rolling and lifting. In this study, a modeling effort is performed to explain the detachment mechanism of a contaminant particle due to the rebounding caused by the vertical collision of the $CO_2$ snow. The Hertz and Johnson-Kendall-Roberts(JKR) theories are employed to describe the contact, adhesion and deformation mechanisms of the particles on a substrate. Numerical simulations are followed for several representative cases, which provide the perspective views on the dynamic characteristics of the particles as functions of the material properties and the initial inter-particle collision velocity.

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Performance Analysis of PCM Cell Search Algorithm for Fast Cell Search in WCDMA Systems (WCDMA. 시스템에서 빠른 셀 탐색을 위한 극성 변조 셀 탐색 알고리즘의 성능 분석)

  • 배성오;임재성
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.28 no.8A
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    • pp.598-606
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    • 2003
  • In this paper, we analyze the performance of the PCM cell search algorithm proposed for fast cell search of WCDMA systems. In order to improve both performance and complexity of the cell search algorithm standardized for WCDMA systems the PCM scheme uses a group of the polarization codes produced by a Gold code generator. The PCM scheme only uses one synchronization channel since the polarization codes modulated on P-SCH can replace the RS codes of S-SCH. Thus, the PCM reduces the BS's transmission power since only one synchronization channel can be used, and it can also reduce the complexity of receiver as compared with the conventional one. In this paper, by defining a numerical model, we analyze the performance of the PCM cell search algorithm in terms of detection probability and mean acquisition time. Consequently, we could demonstrate that the PCM cell search algorithm is superior to the standard WCDMA cell search algorithm.

Limit State Assessment of SCH80 3-inch Steel Pipe Elbows Using Moment-Deformation Angle Relationship (모멘트-변형각의 관계를 이용한 SCH80 3인치 강재배관엘보의 한계상태 평가)

  • Kim, Sung-Wan;Yun, Da-Woon;Cheung, Jin-Hwan;Kim, Seong-Do
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.24 no.3
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    • pp.122-129
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    • 2020
  • To conduct probabilistic seismic fragility analysis for nuclear power plants, it is very important to define the failure modes and criteria that can represent actual serious accidents. The seismic design criteria for piping systems, however, cannot fully reflect serious accidents because they are based on plastic collapse and cannot express leakage, which is the actual limit state. Therefore, it is necessary to clearly define the limit state for reliable probabilistic seismic fragility analysis. Therefore, in this study, the limit state of the SCH80 3-inch steel pipe elbow, the vulnerable part of piping systems, was defined as leakage, and the in-plane cyclic loading test was conducted. Moreover, an attempt was made to quantify the failure criteria for the steel pipe elbow using the damage index, which was based on the dissipated energy that used the moment-deformation angle relationship.

Damage Index Evaluation Based on Dissipated Energy of SCH 40 3-Inch Carbon Steel Pipe Elbows Under Cyclic Loading (주기적 하중을 받는 SCH 40 3-Inch 탄소강관엘보의 소산에너지 기반의 손상지수 평가)

  • Kim, Sung-Wan;Yun, Da-Woon;Jeon, Bub-Gyu;Kim, Seong-Do
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.25 no.1
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    • pp.112-119
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    • 2021
  • The failure mode of piping systems due to seismic loads is the low-cycle fatigue failure with ratcheting, and it was found that the element in which nonlinear behavior is concentrated and damage occurs is the elbow. In this study, to quantitatively express the failure criteria for a pipe elbow of SCH40 3-inch carbon steel under low-cycle fatigue, the limit state was defined as leakage, and the in-plane cyclic loading test was conducted. For the carbon steel pipe elbow, which is the vulnerable part to seismic load of piping systems, the damage index was represented using the moment-deformation angle relationship, and it was compared and analyzed with the damage index calculated using the force-displacement relationship. An attempt was made to quantitatively express the limit state of the carbon steel pipe elbow involving leakage using the damage index, which was based on the dissipated energy caused by repeated external forces.

Effect of iodine restriction on short-term changes in thyroid function in patients with subclinical hypothyroidism

  • Kwon, Obin;Shin, Dong Yeob;Lee, Eun Jig
    • Journal of Nutrition and Health
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    • v.55 no.2
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    • pp.250-262
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    • 2022
  • Purpose: Elevated iodine intake is related to a higher prevalence of subclinical hypothyroidism (SCH). We investigated the short-term effect of dietary iodine restriction on thyroid function in patients with SCH with high iodine intakes. Methods: The iodine levels in 64 SCH patients with serum TSH levels from 4.0 to 10.0 mIU/L and normal serum fT4 levels (n = 64) were assessed using 24-hour urine iodine test results and iodine intake levels calculated using a semi-quantitative food frequency questionnaire. Dietary iodine restriction was not recommended for patients with an iodine intake in the normal range (group A, n = 13), but seaweed restriction was recommended for patients with high iodine intakes (group B, n = 33). Thyroid functions and iodine levels were rechecked after three months. Another eighteen patients were prescribed thyroid hormone replacement therapy according to clinical criteria. Results: Median baseline iodine intake for the 64 patients was 290.61 ㎍/day, and median 24-hour urine iodine was 33.65 µmol/g of creatinine. The major source of dietary iodine was seaweed, which accounted for 72.2% of median baseline intake. Urine iodine and calculated iodine intake levels were positively correlated with serum TSH levels (p < 0.001 and p = 0.027, respectively), and calculated iodine intakes were significantly correlated with urine iodine levels (p = 0.001). In group B, iodine restriction significantly decreased urine iodine (p = 0.042) and TSH levels (p = 0.004), and conversion to euthyroid status was achieved in 16 of the 33 patients (48.5%). Conclusion: Iodine intake and urine iodine levels are correlated with thyroid function in SCH patients, and dietary iodine restriction can aid functional thyroid recovery in patients with elevated iodine intakes.

Clinicopathological evaluation of Childhood Henoch-$Sch{\ddot{o}}nlein$ Purpura(HSP) Nephritis with Nephrotic Syndrome (신증후군을 동반한 Henoch-$Sch{\ddot{o}}nlein$ 신염 환아의 임상병리 적 고찰)

  • Kang Hyeon-Ho;Yoon Kyung-Leem;Cho Byoung-Soo
    • Childhood Kidney Diseases
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    • v.4 no.2
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    • pp.111-119
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    • 2000
  • Purpose : Henoch-$Sch{\ddot{o}}nlein$ purpura(HSP) is a common pediatric discase presenting most frequently with skin, gastrointestinal, joint and renal manifestations. The prognosis of HSP is mainly determined by the involvement of the kidney, but prognostic markers have not been established. We evaluated the patients who have HSP nephritis with nephrotic syndrome. Method : Clinical manifestations and laboratory findings were observed and analyzed in 34 cases with HSP which were manifested by nephrotic syndrome hospitalized at Kyung Hee university Hospital during the period from Jan. 1990 to Dec. 1998. Results : 1) Male to female ratio was 1.3:1, and mean age at onset was 8.3 year. 2) Mean duration from symptom onset to renal biopsy was 10.5 weeks. 3) Proportion of patients presenting with acute nephritis was 32.4$\%$, gross hematuria 17.6$\%$, microscopic hematuria 50$\%$. 4) The findings of renal biopsy were 20 cases of grade II, 11 cases of grade III, 2 cases of grade I, 1 case of grade IV according to classification by ISKDC. 5) Patients with grade I were recovered with no residual defect, but patients with grade IV shows active renal disease(states C). Conclusion : Among the 디le patients with Henoch-$Sch{\ddot{o}}nlein$ purpura accompanying nephrotic syndrome, more aggressive treatment might be needed in patients showing crescents formation on renal biopsy. A prospective study will be needed to explore the progression of this disease.

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Detection of Co-Infection of Notocactus leninghausii f. cristatus with Six Virus Species in South Korea

  • Park, Chung Hwa;Song, Eun Gyeong;Ryu, Ki Hyun
    • The Plant Pathology Journal
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    • v.34 no.1
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    • pp.65-70
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    • 2018
  • Co-infection with two virus species was previously reported in some cactus plants. Here, we showed that Notocactus leninghausii f. cristatus can be co-infected with six different viruses: cactus mild mottle virus (CMMoV)-Nl, cactus virus X (CVX)-Nl, pitaya virus X (PiVX)-Nl, rattail cactus necrosis-associated virus (RCNaV)-Nl, schlumbergera virus X (SchVX)-Nl, and zygocactus virus X (ZyVX)-Nl. The coat protein sequences of these viruses were compared with those of previously reported viruses. CMMoV-Nl, CVX-Nl, PiVX-Nl, RCNaV-Nl, SchVX-Nl, and ZyVX-Nl showed the greatest nucleotide sequence homology to CMMoV-Kr (99.8% identity, GenBank accession NC_011803), CVX-Jeju (77.5% identity, GenBank accession LC12841), PiVX-P37 (98.4% identity, GenBank accession NC_024458), RCNaV (99.4% identity, GenBank accession NC_016442), SchVX-K11 (95.7% identity, GenBank accession NC_011659), and ZyVX-B1 (97.9% identity, GenBank accession NC_006059), respectively. This study is the first report of co-infection with six virus species in N. leninghausii f. cristatus in South Korea.

Fabrication of a shadow mask for OTFT circuit (유기 박막 트랜지스터 회로를 위한 섀도 마스크의 제작)

  • Yi S.M.;Park M.S.;Lee Y.S.;Lee H.S.;Chu C.N.
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2005.06a
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    • pp.1277-1280
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    • 2005
  • A high-aspect-ratio and high-resolution stainless steel shadow mask for organic thin-film transistors (OTFTs) circuit has been fabricated by a new method which combines photochemical machining, micro-electrical discharge machining (micro-EDM), and electrochemical etching (ECE). First, connection lines and source-drain holes are roughly machined by photochemical etching, and then the part of source and drain holes is finished by the combination of micro-EDM and ECE processes. Using this method a $100\;\mu{m}$ thick stainless steel (AISI 304) shadow mask for inverter can be fabricated with the channel length of $30\;\mu{m}\;and\;10\;\mu{m}\;respectively.\;The\;width\;of\;connection line\;is\;150\;\mu{m}$. The aspect ratio of the wall is about 5 and 15, respectively. Metal lines and source-drain electrodes of OTFTs were successfully deposited through the fabricated shadow mask.

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