• 동의생리병리학회지
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• 제31권1호
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• pp.59-64
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• 2017

Scutellaria baicalensis Georgi is one of major herbs used to treat patients with skin diseases diagnosed by wind-heat syndrome. This study was designed to investigate the effects of Scutellaria baicalensis Extract (SBE) on skin lesion of Contact dermatitis (CD) in mice. We investigated the effects of SBE on skin thickness, skin lesions, erythema index and melanin index in vivo. The effects on body weights and spleen/body weight ratio were also investigated in mice with CD induced by topical application of 1-Fluoro-2,4-dinitrofluorobenzene (DNFB). In our results, topical application of SBE lowered skin thickness significantly. In addition, SBE ameliorated skin lesions such as erythema, exudate and petechia in mice with CD. SBE also inhibited erythema index elevated by DNFB significantly. finally, SBE did not affect body weight and spleen/body weight ratio. In conclusion, these data imply that SBE can ameliorate skin lesion of CD such as erythema, exudate and petechia, and be used to treat CD patients with relative safety.

• 동의생리병리학회지
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• 제21권6호
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• pp.1394-1400
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• 2007

This study was designed to investigate the effects of Samul-tang Extract and Bambusae caulis in liquamen(SEB) on the changes in regional cerebral blood flow (rCBF) and mean arterial blood pressure (MABP) in normal rats. The results were as follows ; SBE significantly increased rCBF in a dose-dependent manner, and increased MABP in a dose-dependent manner. This result suggests that SBE significantly increased rCBF by dilating pial arterial diameter. Increase of SBE-induced rCBF was significantly inhibited by pretreatment with indomethacin (1 mg/kg, i.p.), an inhibitor of cyclooxygenase and increase of SBE-induced rCBF was inhibited by pretreatment with methylene blue ($10\;{\mu}g/kg$, i.p.), an inhibitor of guanylate cyclase. Increase of SBE-induced MABP was significantly increased by pretreatment with methylene blue but increase of SBE-induced MABP was decreased by pretreatment with indomethacin. These results suggested that the action of SBE was mediated by cyclooxygenase.

• 한국조경학회지
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• 제15권2호
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• pp.91-100
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• 1987

Main purpose of this study is to test the usefulness of the SBE method in measuring ‘complexity’‘beauty’and ‘friendliness’other than ‘preference’. The study results are as follows. 1) The SBE results are as reliable and valid in measuring ‘complexity’‘beauty’and ‘friendliness’as in measuring ‘preference’. However, the degree of reliability and convergent validity can vary according to the inherent charateristics of those abstract quality themselves. 2) The correlation coefficients among the result of rating, SBE, frequency, and paired comparison methods are very high. 3) The perceived beauty of urban residential landscape reaches highest at the higher complexity level than that of the rural residential landscape.

• Journal of Nutrition and Health
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• 제43권3호
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• pp.215-223
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• 2010

Sasa borealis leaf has been known to have anti-diabetic properties. In this study, we tried to evaluate the effects of Sasa borealis leaf extract (SBE) on the inhibition of $\alpha$-glucosidase activity and postprandial glycemic response following ingestion of four carbohydrate-rich foods; cooked rice, ramen (instant noodle), noodle, and bread. Fourteen healthy female adults consumed 50 g of glucose (control) or one of the four foods containing 50 g of available carbohydrate with or without 2,000 mg of SBE. The activity of $\alpha$-glucosidase was inhibited dose-dependently by SBE. With SBE, blood glucose concentration at 15 min and the positive area under the curve (AUC) of postprandial glycemic response at 15 min and 30 min after consuming each of the four foods were reduced significantly. As the result, total positive AUC during 120 min was decreased in case of taking cooked rice or bread. Glycemic index and glycemic load of the four foods were declined from 13% to 23% with SBE. The results of this study suggest that SBE may be effective for postprandial glucose control by inhibiting $\alpha$-glucosidase activity.

• Clinical Endoscopy
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• 제56권6호
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• pp.716-725
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• 2023

Endoscopic retrograde cholangiopancreatography (ERCP) in patients with surgically altered anatomy is technically challenging. For example, scope insertion, selective cannulation, and intended procedures, such as stone extraction or stent placement, can be difficult. Single-balloon enteroscopy (SBE)-assisted ERCP has been used to effectively and safely address these technical issues in clinical practice. However, the small working channel limits its therapeutic potential. To address this shortcoming, a short-type SBE (short SBE) with a working length of 152 cm and a channel of 3.2 mm diameter has recently been introduced. Short SBE facilitates the use of larger accessories to complete certain procedures, such as stone extraction or self-expandable metallic stent placement. Despite the development in the SBE endoscope, various steps have to be overcome to successfully perform such procedure. To improve success, the challenging factors of each procedure must be identified. At the same time, endoscopists need to be mindful of adverse events, such as perforation, which can arise due to adhesions specific to the surgically altered anatomy. This review discussed technical tips regarding SBE-assisted ERCP in patients with surgically altered anatomy to increase success and reduce the risk of adverse events associated with ERCP.

• Bulletin of the Korean Chemical Society
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• 제34권11호
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• pp.3199-3205
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• 2013

The inclusion behavior of sulfobutylether-${\beta}$-cyclodextrin (SBE-${\beta}$-CD) with perphenazine (PPH) was first studied by flow injection (FI)-chemiluminescence (CL) analysis with proposed $lg[(I_0-I_s)/I_s]=lgK_{P-CD}+nlg[C_{PPH}]$ model and molecular docking. Results showed that a 1:1 complex of SBE-${\beta}$-CD/PPH could online form, with the formation constant $K_{P-CD}$ of $2.57{\times}10^7Lmol^{-1}$ at 298 K. The thermodynamic parameters showed that the inclusion behavior of SBE-${\beta}$-CD/PPH was a spontaneous process by hydrophobic interaction. The molecular docking results revealed PPH entered into the larger cavity of SBE-${\beta}$-CD with two hydrogen bonds. Based on the linear relationship of the decrement of luminol/SBE-${\beta}$-CD/PPH CL intensity against the logarithm of PPH concentration ranging from 0.03 to 30.0 ng $mL^{-1}$, the present FI-CL analysis using luminol/SBE-${\beta}$-CD/PPH system was successfully applied to PPH determination in biological fluids and tablets with recoveries from 94.5 to 105.6% and RSDs less than 2.6% (n = 5).

• 공학교육연구
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• 제8권1호
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• pp.60-70
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• 2005

직업교육의 목적은 산업체 현장에 필요한 인력을 양성 공급하는 것으로, 학생들이 학교 교육을 통하여 산업체에서 요구하는 지식, 기술 등을 습득하는데 있다. 그러나 최근 우리나라의 경우에서는 직업교육이 위축되는 경향을 보이고 있다. 이공계를 지원하는 학생들이 감소하면서 정원이 미달되는 현상이 발생됨으로써 학교 경영이 어려워지는 동시에 직업교육에 대한 투자 효과마저 떨어지고 있다. 본 논문에서는 직업교육 활성화를 위해 일부 국가와 국내에서 적용하고 있는 학교기업 프로그램을 분석하고, 학교기업을 적용할 경우 예상되는 문제점을 예방하고 개선방안을 제시하고자 한다.

• 한국축산식품학회지
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• 제30권5호
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• pp.833-841
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• 2010

본 연구에서는 패티 재료의 육류 일부를 SBE 또는 SBE-밥으로 대체하여 건강지향적인 기능성 패티의 개발 가능성을 알아보고자 하였다. 시제품 패티 3종을 제작하여 이들의 품질 특성과 관능성 및 기호도를 전형적인 표준 패티(Control)와 비교 평가하였다. 시제품 패티는 SBE로 육류의 2.5%를 대체한 것(S)과 SBE-밥으로 육류의 25%(SI) 또는 50%를 대체한 것(SII)이었다. Control 패티에 비해 S, SI 및 SII 패티 모두 수분 함량은 다르지 않았다. 그러나 탄수화물과 조회분 및 Na 함량은 높았고 반면에 지방과 콜레스테롤 및 단백질 함량은 낮았다. 회분과 Na 함량의 증가는 특히 S 패티에서 컸고, 탄수화물의 증가와 지방, 콜레스테롤 및 단백질 함량의 저하는 SI과 SII 패티에서 상당했다. 가열 감소율은 중량, 직경 및 두께 모두에 네 패티 간에 유의적인 차이를 보였는 바, S 패티는 Control 패티에 비해 직경 감소율이 낮았고, SI 패티는 중량과 직경 감소율이 낮았으며, SII 패티는 중량과 직경 감소율이 낮은 반면에 두께 감소율은 컸다. 색도는 S, SI 및 SII 패티 모두 Control 패티에 비해 명도(L)는 낮았으나, 황색도(b)가 높았으며, S 패티의 경우는 적색도(a)도 높았다. pH는 Control 패티에 비해 SI 패티는 동일했으나, S 패티는 높았고, 반면에 SII 패티는 낮았다. 경도는 S 패티는 Control 패티와 같았으나, SI 패티는 낮았고, SII 패티는 더 낮았다. MDA 값은 SII, SI 및 S 패티 순으로 낮았다. 패티의 관능성은 Control 패티에 비해 S, SI 및 SII 패티 모두 색이 좋게 평가되었으며, SI과 SII 패티는 윤기도 높게 평가되었고, 기타 관능성 항목에서는 네 패티 간에 차이를 보이지 않았다. 기호도 조사에서는 Control 패티에 비해 S, SI 및 SII 패티 모두 색은 좋게 평가되었으나, SII 패티는 윤기는 높으나 경도가 낮게, S와 SII 패티는 느끼함과 이취가 낮게, S 패티는 고소함이 낮게, 그리고 맛은 S와 SI 및 SII 패티 모두 낮게 평가되어, S와 SII 패티는 전체적인 기호도가 낮았다. 한편, 이들 패티를 이용하여 제작한 햄버거의 기호도는 Control 패티에 비해 S 패티는 이취와 고소함, 맛 및 전체적인 기호도에서 낮은 평가를 받았으나 SI 패티는 가장 우수하다고 평가되었다. 이는 SI 패티의 SBE 함량이 S와 SII 패티의 절반 수준이었고 SBE-밥의 함량은 SII 패티의 절반이었던 점이 이취가 강하지 않았고 경도의 저하 또한 크지 않았기 때문이라 해석된다. 이와 같은 본 연구결과는 패티 재료의 육류 일부를 SBE 또는 SBE-밥으로 대체할 경우 패티의 수분 함량이나 경도 및 pH에 큰 변화가 없고, 색이 향상되며, 지질산패도가 낮은 우수한 품질 특성을 갖게 되고 또한 가열감소율이 적은 장점을 갖는다는 점과 함께 관능성과 기호도 또한 나빠지지 않음을 확인해 주었다. 그러므로 SBE에 들어있는 생리활성물질을 함유하는 저에너지, 저지방 및 저콜레스테롤의 건강지향적인 기능성 패티의 개발 가능성이 크다고 결론 내릴 수 있겠다.

• International Journal of Automotive Technology
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• 제3권2호
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• pp.53-56
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• 2002

A new generation of the BMW child seat and occupant detection system SBE2 far a smart airbag system is described. The SBE2 system consists of two subsystems: OC (Occupant Classification) and FDS (Field Detection System). The OC system is a force sensitive sensor array that measures a pressure profile. The FDS system detects child seat and occupant according to the change of electrical field generated by four capacitive plates. Combining the signals from both subsystems, the BMW SBE2 system can distinguish fully automatically between a child seat and a person.

• 대한의생명과학회지
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• 제28권1호
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• pp.50-57
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• 2022

In this study, we tried to examine the possibility of developing a dental product such as tooth decay prevention and oral hygiene by manufacturing a natural polymer film for oral use. Natural polymer films were prepared from shark byproduct extract (SBE) and gellan gum (GG). As an antibacterial substance, the antibacterial activity of green tea extract against tooth decay-causing bacteria was measured. An film was prepared by adding green tea extract to the composition of SBE and GG. The mechanical, solubility, moisture content and antibacterial function of the prepared film were investigated in detail. Also, the incorporation of GTE into the SBE/GG film improved the physical performance of the film. Increasing the content of GTE improved the antioxidant and antibacterial properties of the film. Formulation of antimicrobial SBE/GG film containing green tea extract was established and these results evidently showed potential for cavity prevention products application.