• Bulletin of the Korean Chemical Society
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• v.31 no.6
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• pp.1609-1614
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• 2010

Acetylcholinesterase reactivators are crucial antidotes for the treatment of organophosphate intoxication. Standard in vitro test was chosen using a rat brain homogenate as the source of AChE. Screening of reactivation potency was performed with two concentration of reactivator (1000 ${\mu}M$ and 10 ${\mu}M$). Results were compared to established reactivators pralidoxime, methoxime, HI-6, trimedoxime and obidoxime. More than 30 novel reactivators performed equal or better reactivation ability of POX-inhibited AChE compared to currently used reactivators. The structure-activity relationship for reactivators of paraoxon-inhibited AChE was developed.

• YAKHAK HOEJI
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• v.57 no.6
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• pp.426-431
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• 2013

In our previous studies, 6-hydroxy-7-methoxychroman-2-carboxylic acid N-phenylamide (KL-1156) was identified as a good inhibitor of nuclear factor-${\kappa}B$ (NF-${\kappa}B$) activation. In continuation of our study, we describe the structure-activity relationship of chroman derivatives containing N-arylalkyl groups and their NF-${\kappa}B$ inhibitory activities. In addition, inhibitory effects of cell proliferation are evaluated against human cancer cell lines (NCI-H23 and PC-3). The most active compounds 3i and 3j contained diphenylethyl and diphenylpropyl side chain on amide nitrogen.

• KIEAE Journal
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• v.10 no.5
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• pp.57-62
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• 2010

Studies on daylighting of buildings have been continuously increased due to the recent escalating oil price and low-carbon strategies in developed countries. Daylighting of buildings not only saves electric energy, but provide the occupants with a comfort visual environment. Atrium spaces are adopted by many modern buildings to improve daylight performance of deep interior spaces. Among the various types of atria, the four-sided type atrium is frequently adopted by library buildings, governmental buildings and office buildings. This study aims to suggest daylighting design data for adjacent occupied spaces by conducting dynamic simulations using Daysim program. Daylight Factor(DF), Daylight Autonomy(DA) and Useful Daylight Illuminance(UDI) levels for 12 measurement points in adjacent occupied spaces were calculated for square-shape four-sided atria with different SAR(Section Aspect Ratio) and different canopy transmittance.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.66 no.2
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• pp.383-386
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• 2017

In this study, we introduce a triple-band flexible implantable antenna that is tuned by using a ground slot in three specific bands, namely Medical Implanted Communication Service (MICS: 402-405 MHz) for telemetry, the midfield band (lower gigahertz: 1.45-1.6 GHz) for Wireless Power Transfer (WPT), and the Industrial, Scientific and Medical band (ISM: 2.4-2.45 GHz) for power conservation. This antenna is wrapped inside a printed 3D capsule prototype to show its applicability in different implantable or ingestible devices. The telemetry performance of the proposed antenna was simulated and measured by using a porcine heart. From the simulation and measurement, we found that use of a ground slot in the implantable antenna can improve the antenna performance and can also reduce the Specific Absorption Rate (SAR).

• Journal of the Korean Institute of Navigation
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• v.18 no.4
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• pp.119-136
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• 1994

In Korea, the System of search and rescue in water have came into force on the basis of the Korea Life Saving and Rescue Act. 1961. But It's a premodern administration law which is not fit for an international system of the search and rescue and become disconnected with reality in Korea. Recently the marine casualties occur frequently in Korea coastal area, therefore, we need to amend the 1961 Act. The amendment which is carried out by the Korea Maritime Police Agency is a provision to receive International convention(SAR, 1979). The amendment of this Act will give a epoch-making change to Korean policy of the life-saving and rescue, security to marine safety and contribution to National positon on system of "Search and Rescue". In this thesis, I propose a development scheme to be conductive to original task on "Search and Rescue" of International Convention in Korea Life Saving and Rescue Act(Amendment, 1994).t(Amendment, 1994).

• Proceedings of the PSK Conference
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• 2002.10a
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• pp.351.2-351.2
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• 2002

We have previously reported the synthesis and cytotoxic activities of a series of azaanthraquinone derivatives on the model of doxorubicin(Dox). Dox is known to intercalate into DNA and to inhibit topoisomerase II activity. But in the case of Quinone compounds like Dox. its use is limited because of systemic toxicities. primarily cardiotoxicity and myelosuppression. In this study. we describe the synthesis of benzoquinoxaline derivatives as DACA analogue. DACA has a neutral chromophore and acridine moiety and posions both topoisomerases I and ll with DNA intercalating activity. In order to delineate the SAR of benzoquinoxaline derivatives. an effcient sythetic rout to the target compounds without quinone group. Various attempted removal of quinone from benzoquinoxlinedione was unsuccessful. Diels-Alder rout applied for the synthesis of the target compounds will be discussed.

• Proceedings of the KSRS Conference
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• 2003.11a
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• pp.44-46
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• 2003

In 1996, Thailand's participation in the Pacific Rim as a part of NASA's Mission to Planet Earth (MTPE) Program, was titled 'AIRSAR Thailand Project'. In this project the Department of Land Development utilized Topographic SAR (TOPSAR) which had multi-frequencies: C band, L band, and P band with multi-polarization: HH, VV, and HV as well as C band VV DEM. Satellite data such as LANDSAT TM was also utilized for optimal use. Results of AIRSAR image processing including data fusion among difference wavelength bands and polarization revealed the quality of AIRSAR that best suit for detection of agricultural land uses. The HH-L band AIRSAR was proven to be useful to distinguish among crop types when combined with appropriate data. The HH, VV, and HV-P band enhanced surface characteristics of swamp forest and wetland. In addition, TOPSAR has its great advantage for identification of salt farms and shrimp ponds.

• International conference on construction engineering and project management
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• 2011.02a
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• pp.389-394
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• 2011

In many parts of the world, low cost housing used to be built and maintained by the governments, based on designs and detail specifications prepared by the public sector with construction carried out by contractors. Results vary due to differences in design standards, workmanship and property management, depending also on the neighbourhood's care of the estates and their pattern of usage. In the UK, where Private Finance Initiative (PFI) has been used for infrastructure projects, there have been successful cases of city estate being transformed by PFI. These PFI housing schemes involve new-build, refurbishment as well as facility management. Unlike traditional construction, which is based on prescriptive specifications, PFI housing is based on output specifications. A study has been undertaken to compare the two specification approaches as they are applied to housing estate. Results are enlightening and serve as good reference to cities such as Hong Kong SAR and Singapore, where public housing provisions have been a major concern of their citizens as the building stock gets older.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.44 no.5
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• pp.673-681
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• 2024

The purpose of this study was to estimate the flood flow and the range of inundation in the downstream area of the Aprokgang(Riv.) that occurred in 2024 using satellite images. The study area was the Aprokgang(Riv.) watershed, the longest river in North Korea. Satellite image Sentinel-1A(SAR-C) data was used for flood analysis before and after the flood. As a result of the analysis of the inundation range using satellite images, it was confirmed that there was a change in the water surface before and after the flood. However, the image after the flood was taken six days after the peak discharge of the flood, so there are limitations in extracting the accurate extent of the flooding. As a result of the analysis using satellite precipitation and ground observed rainfall, the rainfall exceeded 500-year rainfall amount, and the peak-flow was simulated as 85,102 m³/s. As a result of analyzing the inundation range by using the contour lines from AW3D30, it was determined that the inundation occurred around the 15 m contour line. In the future, it is need to conduct a study that can extract more scientifically the inundation range through the use of the inundation analysis model.

• Asia-Pacific Journal of Business
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• v.11 no.2
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• pp.189-206
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• 2020

Purpose - The purpose of this study is to clarify the mediating effect of profitability and activity in the relationship between productivity and stock return, assuming that the productivity of the company will affect share prices with the parameters of profitability and activity. Design/methodology/approach - The study extracted productivity indicators, profitability indicators, activity indicators, and share price-related indicators from 1999 to 2018 of non-financial enterprises listed on the securities market, and then classified them into three factors: productivity (labor productivity LP, capital productivity CP), activity (TT), and profitability (net profit rate NI, operating profit ratio OI) through the factor analysis method, and analyzed the impact of each factor on the stock return through steps 1 to 3. Findings - The regression analysis shows that productivity has a significant positive effect on the stock return through the full mediating effect of profitability and activity. Research implications or Originality - In a situation where the relationship between productivity and profitability is not clear, this study is meaningful in that it has empirically analyzed that productivity has a positive effect on the stock return by mediating effects of profitability and activity.