• Title/Summary/Keyword: SAM-X

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Glucose Sensors Using Lipoic Acid Self-Assembled Monolayers

  • Kim, Ji Yeong;Nakayama, Tadachika;Kim, Jae-Hun;Kim, Sang Sub
    • Journal of Sensor Science and Technology
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    • v.23 no.5
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    • pp.295-298
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    • 2014
  • A novel approach to fabricating high-performance glucose sensors is reported, which is based on the process of self-assembled monolayers (SAMs). In this study, we have particularly used ${\alpha}$-lipoic acid (LA) SAMs for the glucose sensors. To our best knowledge, this study is the first one to use LA as SAMs for this purpose. N-hydroxysuccinimide (NHS) and 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC) were deliberately attached at the same time on the LA SAM. Then, glucose oxidase ($GO_X$) and horseradish peroxidase (HRP) were sequentially immobilized. Thus, the HRP/$GO_X$/NHS-EDC/LA-SAM/Au/Cr/glass working electrode was developed. The glucose-sensing capability of the fabricated sensor was systematically measured by the use of cyclic voltammetry in the range of 1-30 mM glucose in phosphate-buffered saline. The result showed a good sensitivity, that is, as high as $27.5{\mu}A/(mM{\cdot}cm^2)$. This result conspicuously demonstrates that LA can be one of promising substances for use as SAMs for accurately monitoring trace levels of glucose concentration in human blood.

A Study on the Reaction of Al-1% Si with Ti-silicide (Al-1% Si층과 Ti-silicide층의 반응에 관한 연구)

  • Hwang, Yoo-Sang;Paek, Su-Hyon;Song, Young-Sik;Cho, Hyun-Choon;Choi, Jin-Seog;Jung, Jae-Kyoung;Kim, Young-Nam;Sim, Tae-Un;Lee, Jong-Gil;Lee, Sang-In
    • Korean Journal of Materials Research
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    • v.2 no.6
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    • pp.408-416
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    • 1992
  • Stable TiS$i_2$was formed by RTA on single-Si and on poly-Si. Subsequently, an Al-1% Si layer with 600-nm thick was deposited on top of the TiS$i_2$, Finally, the specimens were annealed for 30min at 400-60$0^{\circ}C$in $N_2$ambient. The thermal stability of Al-1% Si/TiS$i_2$bilayer and interfacial reaction were investigated by measuring sheet resistance, Auger electron spectroscopy (AES), and scanning electron microscopy (SEM). The composition and phase of precipitates formed by the reaction of Al-1% Si with Ti-silicide were studied by energy dispersive spectroscopy (EDS), X-ray diffraction (XRD). In the case of single-Si substrate the reaction of Al-1% Si layer with TiS$i_2$layer resulted in precipitates, consuming all TiS$i_2$layer at 55$0^{\circ}C$. On the other hand, the disappearance of TiS$i_2$on poly-Si occurred at 50$0^{\circ}C$ and more precipitates were formed by the reaction of Al-1% Si/TiS$i_2$on potty-Si substrate than those of the reaction on single-Si substrate. This phenomenon resulted from the fact that Ti-silicide formed on poly-Si was more unstable than on single-Si by the effect of grain boundary. By EDS analysis the precipitates were found tobe composed of Ti, Al, and Si. X-ray diffraction showed the phase of precipitates to be theT$i_7$A$l_5$S$i_12$ternary compound.

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Effects on osteoporosis of Senescence Accelerated Mice (SAM) P6 by Injection of Placenta extracts ($Beuronel^{(R)}$) (SAM p6 mouse에서 자하거 주사제의 골다공증 개선에 대한 연구)

  • Kim, Mi-Jung;Yum, Do-Young;Koo, Bon-Taq;Ma, Jin-Yeul;Shin, Hyun-Kyu;Lee, Mi-Young;Shin, Dong-Won;Park, Jong-Cheol;Yu, Young-Beob
    • The Korea Journal of Herbology
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    • v.22 no.3
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    • pp.77-83
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    • 2007
  • Objectives : The purpose of this study was to examine the effects of the Hominis placenta extracts on improvement of senile osteoporosis (Type 2) in SAM P6. In traditional Oriental medicine, Placenta (Jahageo) is indicated for insufficiency of blood and tidal fever due to steaming bone disorder. Methods : At 10 weeks after birth, Placenta ex. was given 100 mL, 200 ml/kg/day, i.p. 3 times a week for 4 weeks in SAM P6 mice. And then we measured complete blood cells, blood urea nitrogen, creatinine, inorganic phosphate and total iron. In addition, we tested bone mineral density (BMD) using the soft X-ray. Results : As a result, in SAM P6, injection of Placenta ex. (200 mL) increased in RBC, HB and PLT, in comparison with control group. It was also found that the inorganic phosphate levels increased significantly in the injection groups of the Placenta ex. from that of the control group, but blood urea nitrogen was no significant. Moreover, Placenta ex. were showed a trend of increase in bone mineral density (BMD) of the vertebrae lumbales and tibia in P6 mice. Conclusions : These findings suggest that Placenta ex. are effective in preventing bone loss in SAMP6.

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The Study on Improving Accuracy of Land Cover Classification using Spectral Library of Hyperspectral Image (초분광영상의 분광라이브러리를 이용한 토지피복분류의 정확도 향상에 관한 연구)

  • Park, Jung-Seo;Seo, Jin-Jae;Go, Je-Woong;Cho, Gi-Sung
    • Journal of Cadastre & Land InformatiX
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    • v.46 no.2
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    • pp.239-251
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    • 2016
  • Hyperspectral image is widely used for land cover classification because it has a number of narrow bands and allow each pixel to include much more information in comparison with previous multi-spectral image. However, Higher spectral resolution of hyperspectral image results in an increase in data volumes and a decrease in noise efficiency. SAM(Spectral Angle Mapping), a method based on vector inner product to compare spectrum distribution, is a highly valuable and popular way to analyze continuous spectrum of hyperspectral image. SAM is shown to be less accurate when it is used to analyze hyperspectral image for land cover classification using spectral library. this inaccuracy is due to the effects of atmosphere. We suggest a decision tree based method to compensate the defect and show that the method improved accuracy of land cover classification.

Quantitative Mass Spectrometric Analysis of Mixed Self-Assembled Monolayers for Biochips

  • Son, Jin Gyeong;Shon, Hyun Kyong;Hong, Daewha;Choi, Changrok;Han, Sang Woo;Choi, Insung S.;Lee, Tae Geol
    • Proceedings of the Korean Vacuum Society Conference
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    • 2013.02a
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    • pp.275-275
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    • 2013
  • Formation and characterization of self-assembled monolayers (SAMs) on various surfaces are the essential basis for many other applications, including molecular switches, biosensors, microfluidics, and fundamental studies in surfaces and interfaces. To improve the performance at these applications, it is a key to control the quantity of each molecule in various mixed SAMs on the surface. In this study, using mixed SAM of carbamate-based hydroquinone (HQ)-PhBr and11-mercaptoundecanol, the quantitative mass spectrometric method of mixed SAM was developed based on comparison study with XPS and FT-IR methods. In addition, our method was applied to another mixed SAM of biotinylated PEG alkane thiol and 11-mercaptoundecanol for verification purpose. Time-of-flight secondary mass spectrometry (ToF-SIMS) analysis was performed to identify and quantify each molecule of mixed SAM along with principal component analysis (PCA). Since there is no matrix effect in the X-ray photoelectron spectroscopy (XPS) and Fourier transform-infrared (FT-IR) techniques, we compared ToF-SIMS results with XPS and FT-IR results. Because PCA results from ToF-SIMS analysis are well matched with XPS and FT-IR results from both mixed SAMs, we are expecting that our method will be useful to identify and quantify each molecule in various mixed SAMs.

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A Case Report on Simple Pelvic Fracture with Ostomy (단순 골반 골절된 장루술 환자 치험 1례)

  • An, Hunmo;Kim, Jun-Cheol;Na, Sam-Sik
    • Journal of Korean Medical Ki-Gong Academy
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    • v.13 no.1
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    • pp.1-18
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    • 2013
  • Objective : The objective of this study is to report the effectiveness of conservative treatment on simple pelvic fracture with ostomy. Methods : A female patient 65 years old with ostomy, who were diagnosed as simple pelvic fracture by X-ray, were treated with conservative treatment by herbal medication with acupuncture and physical therapy. We evaluated the effectiveness by checking X-ray, Digital Infrared Thermal Imaging(D.I.T.I.). Results : The symptoms of the patient got improved and X-ray showed the fracture were healing. Conclusions : Conservative korean medical treatment can be effectively used for a patient with simple pelvic fracture and ostomy.

Seed Variability Test by 2,3,5-Triphenyltetrazolium Chloride (염화(鹽化)트리페닐테트라졸륨에 의(依)한 종자활력검정(種子活力檢定)에 관(關)한 연구(硏究))

  • Kim, Sam-Sik
    • Journal of Korean Society of Forest Science
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    • v.26 no.1
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    • pp.23-30
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    • 1975
  • To elucidate the dependability of seed variability determination by tetrazolium, 15 tree species were checked. For the comparison of potential germinability for these tree seeds, x-ray photography and routine germination test in a incubator were implemented. Though there were considerable differences of seed variability in percentage between germination test and tetrazolium test, the judgement by tetrazolium test and x-ray test gave similar results. These findings indicated that tetrazolium test is a reliable method if treated and inferred properly. Solution of 0.25 percent tetrazolium could give a complete colour reaction as well as 0.50 percent solution.

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X-ray Crystal Structure of Hetaryl Leuco-TAM Dyes, (2Z,2'E)-2,2'-(2-Phenyl Propane-1,3-diylidene) Bis(1,3,3-trimethyl indoline) Derivatives

  • Keum, Sam-Rok;Roh, Se-Jung;Kim, Young-Nan;Im, Do-Hyuck;Ma, So-Young
    • Bulletin of the Korean Chemical Society
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    • v.30 no.11
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    • pp.2608-2612
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    • 2009
  • The unequivocal solid-state structure and stereochemistry of the hetaryl leuco-TAM dye, 2,2’-(2-phenyl propane- 1,3-diylidene) bis(1,3,3- trimethylindoline) derivatives were established using X-ray single crystal analysis. The X-ray crystal analysis showed that the (Z, E)-isomers only formed stereoselectively, with a so-called “threebladed propeller” conformation, from the reaction of a Fischer base and benzaldehyde derivatives. These isomers were stacked in a juxtaposition to form a dimer or a double dimer, adopting either a triclinic, with P-1, or monoclinic crystal system with a space group P21/n in the unit cell of the crystal.

A simulation study on predicting current collection performance with respect to the contact wire tension in 400km/h test run of the next high speed train HEMU-400X (차세대 고속철도 최고속도 시험에서 전차선 장력 증가 단계별 집전 성능 예측 시뮬레이션)

  • Kwon, Sam-Young;Park, Chun-Soo;An, Seung-Hwa
    • Proceedings of the KSR Conference
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    • 2009.05b
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    • pp.201-206
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    • 2009
  • In the testing stage of HEMU-400X(next Korean high speed train) developing project, maximum speed(400km/h) tests will be conducted. On present and near future conditions of the overhead contact lines, 400km/h is over the design speed criteria. The predictions of current collection performance including the percentage loss of contact(arcs level) parameter through dynamic interaction simulation of HEMU-400X maximum speed test run are described in this paper. Various simulations are conducted at the condition of two different contact wire tensions to draw the proper contact wire increasing values in the 400km/h test line under the available contact wire tension supporting condition of that line.

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Decomposition of Carbon Dioxide using $Zn_{x}Fe_{3-x}O_{4-{\delta}}$ (($Zn_{x}Fe_{3-x}O_{4-{\delta}}$를 이용한 이산화탄소의 분해)

  • Yang, Chun-Mo;Cho, Young-Koo;Rim, Byung-O
    • Journal of the Korean Applied Science and Technology
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    • v.17 no.1
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    • pp.55-61
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    • 2000
  • $Zn_{x}Fe_{3-x}O_{4}(0.00.<X<0.08)$ was synthesized by air oxidation method for the decomposition of carbon dioxide. We investigated the characteristics of catalyst, the form of methane by gas chromatograph after decomposition of carbon dioxide and kinetic parameter. $Zn_{x}Fe_{3-x}O_{4}(0.00.<X<0.08)$ was spinel type structure. The surface areas of catalysts($Zn_{x{Fe_{3-x}O_{4}(0.00.<X<0.08)$) were $15{\sim}27$ $m^{2}/g$. The shape of $Zn_{0.003}Fe_{2.997}O_{4}$ was sphere. The optimum temperature for the decomposition of carbon dioxide into carbon was $350^{\circ}C$. $Zn_{0.003}Fe_{2.997}O_{4}$ showed the 85% decomposition rate of carbon dioxide and the degree of reduction by hydrogen(${\delta}$) of $Zn_{0.003}Fe_{2.997}O_{4}$ was 0.32. At $350^{\circ}C$, the reaction rate constant and activation energy of $Zn_{0.003}Fe_{2.997}O_{3.68}$ for the decomposition of carbon dioxide into carbon were 3.10 $psi^{1-{\alpha}}/min$ and 0.98 kcal/mole respectively. After the carbon dioxide was decomposed, the carbon which was absorbed on the catalyst surface was reacted with hydrogen and it became methane.