• 한국융합학회논문지
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• 제8권9호
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• pp.41-47
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• 2017

본 연구에서는 제4차 산업혁명의 핵심 요소인 인공지능 기술의 발전에 불가피하게 수반될 수 있는 부작용을 최소화하기 위한 제도적 보완점을 도출하기 위한 선행 연구로서, 인공지능 기술 적용의 대표적인 유형에 해당하는 로보어드바이저가 해킹되어 시세조종 행위를 범하는 구체적인 경우에 있어서 현행 법체계에 따른 책임관계가 어떠한지 검토하고자 하였다. 현행 법체계가 기본적으로 해킹 행위 및 시세조종 행위를 엄격히 금지하는 입장을 취하고 있으나, 로보어드바이저 운용사는 평소 해킹 방지를 위한 보호조치 의무를 준수할 경우 해킹에 따른 시세조종 행위로 일반 투자자들에게 대규모 피해가 발생하여도 이에 대한 법적 책임을 면할 수 있는 등 피해자 보호에 미흡한 것으로 확인되었다. 본 연구를 바탕으로 이러한 문제를 극복하기 위한 제도적 보완점 도출에 관한 후속 연구가 필요하다.

• 한국구조물진단유지관리공학회 논문집
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• 제26권6호
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• pp.182-192
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• 2022

취성파괴는 구조물의 파괴거동 중 하나로서 구조재료의 내진성능에 큰 영향을 미친다. 하중속도는 취성파괴의 주요 발생원인 중 하나로 작용하며, 특히 지진과 같은 상황에서 건축물에 높은 하중속도가 작용하게 된다. 하지만 현재 국내·외 강구조 보-기둥 접합부의 내진성능평가는 대부분 정적실험을 통해 수행되고 있다. 따라서 기존 내진성능평가에서는 지진 시의 높은 하중속도에 의한 재료 인성 저하 및 최대변형률 감소 등의 요소에 따른 취성파괴가 충분히 고려되지 않았을 가능성이 존재한다. 본 연구에서는 기존 실험방법에 따른 낮은 하중속도에서의 정적실험과 진동대를 이용한 높은 하중속도에서의 동적실험을 각각 실시한다. 각 실험결과에 따른 파괴형상 및 구조성능 등을 비교·분석하고 최종적으로 하중속도의 크기가 접합부의 내진성능에 미치는 영향을 분석한다.

• 대한방사선기술학회지:방사선기술과학
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• 제46권6호
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• pp.535-542
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• 2023

This study aimed to implement a deep learning model that can perform quantitative quality control through ACTS software used for quantitative evaluation of ACR phantom in CT quality control and evaluate its usefulness. By changing the scanning conditions, images of three modules of the ACR phantom's slice thickness (ST), low contrast resolution (LC), and high contrast resolution (HC) were obtained and classified as ACTS software. The deep learning model used ResNet18, implementing three models in which ST, HC, and LC were learned with epoch 50 and an integrated model in which three modules were learned with Epoch 10, 30, and 50 at once. The performance of each model was evaluated through Accuracy and Loss. When comparing and evaluating the accuracy and loss function values of the deep learning models by ST, LC, and HC modules, the Accuracy and Loss of the HC model were the best with 100% and 0.0081, and in the integrated model according to the Epoch value, Accuracy and Loss with epoch 50 were the best with 96.29% and 0.1856. This paper showed that quantitative quality control is possible through a deep learning model, and it can be used as a basis and evidence for applying deep learning to the CT quality control.

• Molecules and Cells
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• 제43권5호
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• pp.419-430
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• 2020

The liver is an important organ in the regulation of glucose and lipid metabolism. It is responsible for systemic energy homeostasis. When energy need exceeds the storage capacity in the liver, fatty acids are shunted into nonoxidative sphingolipid biosynthesis, which increases the level of cellular ceramides. Accumulation of ceramides alters substrate utilization from glucose to lipids, activates triglyceride storage, and results in the development of both insulin resistance and hepatosteatosis, increasing the likelihood of major metabolic diseases. Another sphingolipid metabolite, sphingosine 1-phosphate (S1P) is a bioactive signaling molecule that acts via S1P-specific G protein coupled receptors. It regulates many cellular and physiological events. Since an increase in plasma S1P is associated with obesity, it seems reasonable that recent studies have provided evidence that S1P is linked to lipid pathophysiology, including hepatosteatosis and fibrosis. Herein, we review recent findings on ceramides and S1P in obesity-mediated liver diseases and the therapeutic potential of these sphingolipid metabolites.

• 지식경영연구
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• 제21권1호
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• pp.79-98
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• 2020

The majority of research on institutional theory suggests that the new institutional practices presented by national governments and expert groups is a legitimate demand by society, and that the organization is a passive actor that accepts it. However, individual organizations often perform so-called decoupling acts that run their organizations in their own way instead of following the way the system requires, despite the pressures of a strong institutional environment. In this study, the decoupling behavior of these organizations can be varied by the characteristics of the highest decision maker in the organization based on the upper-echelon theory(UET) even if there is no difference in pressure experienced by individual organizations, and their relationship is empirically analyzed among secondary educational institutions that are relatively strongly regulated by the government. According to the analysis of 192 high schools in Korea, the female principal, the younger the principal, and the higher the educational background, the more likely they are to engage in decoupling behavior that are different from the intent and content of government policies. Therefore, from the results of this study, meaningful theoretical and practical implications can be provided for researchers and managers in the field of knowledge management research.

• 미생물학회지
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• 제40권2호
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• pp.73-80
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• 2004

Coenzyme Q는 지용성 퀴논 유도체로서 미토콘드리아의 내막과 원핵생명체의 세포막에 위치하는 전자전달계에서 전자 운반체로 이용되며 또한 항산화제의 기능도 갖는다. Coenzyme Q의 생합성에 관여하는 Saccharomyces cerevisiae의 coq4 유전자에 유사성을 나타내는 Neurospora crassa coq-4유전자를 클로닝하여 S. cerevisiae coq4 돌연변이체에서 기능적으로 발현하였다. 상보된 S. cerevisiae 균주들은 coenzyme $Q_{6}$의 생산능력을 회복하였으며 정상적인 성장률을 보였다. 또한 linoleic acid 및 linolenic acid와 같은 불포화지방산에 대한 낮은 감수성을 보였다. N. crassa의 COQ4 단백질은 39.7 kDa의 분자량을 갖는 347개의 아미노산으로 구성되어 있는 것으로 예상되며, S. cerevisiae의 Coq4p와 35%의 일치도 및 52%의 유사도를 보인다.

• 통상정보연구
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• 제8권4호
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• pp.23-41
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• 2006

The present paper aims to examine the Influences of on line word of mouth(WOM) information valence and information contents to the information searcher. Specially, to examine the interaction effect it's two variables. For that purpose, we categorize WOM information valence into two subcategories; positive and negative, and WOM content into two subcategories; objective evaluation and subjective evaluation. We conducted experimentation design 2*2 and subjects are asked to their attitude and purchase intention after they are exposed each of four different types of WOM information. The result can be summarized as follow; First, the negative WOM has stronger effect on consumer's attitude and purchase intention than positive. Second, factual WOM has stronger effect on consumer's attitude and purchase intention than subject. Finally, when consumer face negative WOM, subjective WOM has more effect on consumer's attitude and purchase intention than factual. On the contrary, when consumer face positive WOM, factual WOM has more effect on consumer's attitude and purchase intention than subject. In conclusion, the korean Foreign Trade Act and other relative acts should be revised, and both educational services and health services should be contained within the definition of "the international trade" for the governmental benefits of supporting the services exportation.

• 대한의생명과학회지
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• 제15권4호
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• pp.349-353
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• 2009

Lysophosphatidic Acid (LPA) is a bioactive lysophospholipid that is a potent signaling molecule able to provoke a variety of cellular responses in many cell types such as differentiation, inflammation and apoptosis. In this study, we have investigated the effect of LPA on Nitric oxide (NO)-induced apoptosis in rabbit articular chondrocytes. LPA dramatically reduced NO induced apoptosis of chondrocytes determined by phase contrast microscope and MTT assay. When chondrocytes alone treated with LPA, LPA induced phosphorylation of p70S6kinase, a serine/threonine kinase that acts downstream of phosphatidylinositol 3,4,5-trisphosphate (PIP3) and phosphoinositide-dependent kinase-1 (PDK-1) in the PI3 kinase pathway, dose-dependently detected by Western blot analysis. Phosphorylation of p70S6k with LPA was reduced expression of p53 in NO-induced apoptosis of chondrocytes. Also, inhibition of p70S6kinase with rapamycin was enhanced expression of p53 in chondrocytes. Our findings collectively suggest that LPA regulates NO induced apoptosis through p70S6kinase pathway in rabbit articular chondrocytes.

• 복식
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• 제57권10호
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• pp.1-10
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• 2007

The 21th century is the time-area where knowledge, information and culture are considered as the pivotal factor for keeping society. Thus, this affects every part which consists of culture. By 2000, various cultural changes create several culture trends all over the world. Above all, advent of CHAV is the remarkable cultural phenomenon because of its life style, fashion and self-awareness. This study analyzes CHAV's life style and fashion based on regarding it as subordinate culture. In terms of these aspects, CHAV's fashion can be divided into three parts by its inner and outer traits. The first is merrymaking style which is composed of combination, parody and excessive decoration of different factors. This is a kind of Pop-Art style that imitates mass consuming culture. The second is ostentation style which emphasizes CHAV's traits and acts group behavior. The third is violence style. CHAV tries to appear violent and indifferent for gaining their rights and power. As a result, CHAV is the rebounding phenomenon that means psychological fear and conflict which neglected people have to resist official authority.

• The Journal of Asian Finance, Economics and Business
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• 제7권10호
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• pp.95-107
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• 2020

This study analyzes the effect of corporate social responsibility (CSR) activity on investors' heterogeneous beliefs. The hypothesis of this study is based on the conflicting effects of CSR activities on firm value and earning's quality. Investors' heterogeneous beliefs used in the empirical analysis of this study are trading volume, and CSR activity is measured by the KEJI Index (Korea Economic Justice Institute Index). This study performs an empirical analysis using regression analysis including control variables. CSR activities are found to have a positive relationship with trading volume. This is consistent regardless of the low and high accounting information (earning's quality). It can be interpreted that Korea's CSR activity acts as an incentive to increase investors' heterogeneous beliefs about target companies. In other words, it implies that the investor judges CSR activities negatively when evaluating firm value. This study could have a policy implication in that it analyzes how CSR activities affect investors' decision-making. In other words, this study analyzed CSR activities from the perspective of shareholders. Therefore, this study is expected to provide useful information for policymaking by regulatory agencies. In particular, its contribution is to presents data that CSR activities can be a negative factor in evaluating firm values.