• Archives of Plastic Surgery
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• 제49권3호
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• pp.315-318
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• 2022

Aqualyx (Marllor International Ltd, Rimini, Italy) was originally developed in Italy by Professor Pasquale Motolese and has been commercially available since 2009. It is a deoxycholate, aqueous gelatinous solution mixed with saline and buffering compounds. It is the only drug approved by the European Union for the reduction in localized fat. Aqualyx is sold exclusively to doctors and nurses trained in intralipotherapy. In the case of our patient, the product administered was advertised as Aqualyx, but was not administered by a trained health professional and was administered too superficially. The patient developed severe pain following the injection and was unable to sit for several weeks. There was localized skin necrosis, and palpable collections where the injection was administered. Our initial suspicion was development of an abscess or hematoma. To characterize further, we arranged an ultrasound scan that showed a "superficial hypoechoic lesion" but no deeper infection or spread. The numerous painful nodules ruptured onto the skin surface, resulting in purulent and bleeding lesions. This case demonstrates the importance of appropriate training and competence in performing cosmetic procedures including injections and fat dissolving treatments.

• 분석과학
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• 제19권1호
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• pp.103-106
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• 2006

A 35-year-old Perubian who suffered from grand mal seizures died in the aircraft on his way from the United States to Hongkong via Incheon international airport of Korea. While performing the autopsy, 115 packs made with double layer of transparent film and black plastic bag containing cocaine were found in the ileum and large intestine. Among of them, 3 packs were ruptured. To determine the concentration of cocaine and its metabolites, blood, urine, bile, liver, spleen, heart, kidney, brain and gastric contents were taken and toxicological analysis was performed. Gas chromatography/mass spectrometry (GC/MS) following liquid-phase extraction using chloroform:isopropanol (=9:1) and derivatization with bis(trimethylsilyl)-trifluoroacetamide (contains 1% trimethylchlorosilane) was performed. High levels of cocaine, benzoylecgonine (BE) and ecgonine methylester (EME) were found in the postmortem blood (0.96, 3.09 and $5.59{\mu}g/mL$) and urine (32.85, 145.35 and $53.17{\mu}g/mL$), respectively. Cocaine and its metabolites were also detected in all other biological specimen.

• Structural Engineering and Mechanics
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• 제90권3호
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• pp.301-311
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• 2024

Different methods have been proposed in the literature for splicing the reinforcing bars in the construction of concrete structures, which are alternatively used depending on design requirements. The most common approach is the lap splicing which is known as a cost-effective method although, its main disadvantages including congestion of bars at the lap zone and consequently, material wastage has motivated utilization of the other techniques such as mechanical splices (couplers). To better evaluate the performance of the couplers, 6 reinforced concrete (RC) beams whose difference is only the type and location of splices have been experimentally studied in this paper. Based on the results, the mechanical connection of the bars did not markedly affect the load-carrying capacity of the specimens. Moreover, it was observed that after applying the loads and failure of the specimens, none of the bars ruptured at the splice location and all couplers remained undamaged.

• 한국간담췌외과학회지
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• 제26권1호
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• pp.113-117
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• 2022

Gallbladder cancer has a poor prognosis, especially in peritoneal carcinomatosis related to perforation of the gallbladder followed by bile spillage. Previously, curative-intent treatment was not considered in carcinomatosis from cancer of the biliary tract. A 72-year-old male was referred to the hospital with a perforated gallbladder cancer. Intraoperatively, the tumor was confined to the gallbladder and liver. We presented a case of intention-to-curative resection of perforated gallbladder cancer followed by intraoperative hyperthermic intraperitoneal chemotherapy.

• 대한간호학회지
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• 제1권1호
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• pp.64-76
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• 1970

This report will present a clinical and statistical analysis of 210 case of Ectopic pregnancies who were treated at the Department of Obstetrics and Gynecology at Chung Nam Medical Center from January, 1966 to March, 1970. The results obtained are as follows; 1. The total number of Ectopic pregnancies was 8.22%. 2. The occurrence of Ectopic pregnancy was high in June(13.81%), low in October(2.98%). There was a higher occurrence of Ectopic pregnancy in the summer than in the winter. 3. The average age of all patients was 33.25 years. The most frequent age for this type of pregnancy was 31-35 years (32.86%) . The youngest patient was 18 years old and the oldest was 50. 4. Multipara occurred in 82.38% of the cases; Mulipara in 17. 62% and the occurrence of primipara was especially high, 20.95%. 5. 48.09% of the women had previously experienced normal deliveries; 42.8% had received artificial abortions and 5.23% had experienced spontaneous abortions. 3.8% had a previous history of Ectopic pregnancy. It was found that the occurrence of Ectopic pregnancy was more frequent in those women who had a D & C in the Past. 6. The average length of infertility was 21.7 months. The shortest length was 60 days; longest period of infertility was 19 years. 7. The occurrence of Ectopic pregnancy is higher (29.27%) in patient who have experienced only one previous D & C. The total number of patients who received a D & C was 58.57%. 3. Ectopic symptoms appeared during the first 4.7 weeks (mean) and most frequently occurred between the 5th and 6th weeks (48.57%) of pregnancy. The Symptoms were: -99.04% complained of lower abdominal pains. -80.95% experienced abnormal uttering bleeding. -42.38% experienced bleeding before the occurrence of pain. -18.57% experienced pain before the occurrence of bleeding. -8.57% experienced both pain and bleeding. -7.62% experienced only bleeding. -22.86% experienced only pain. 9. In-77.62% of the cases the annexal mass palpated. 91.42% complained of abdominal tenderness. 42.38% complained of pain when the cervix was examined. 10. Culdocentesis was performed in 86.19% of the cases. In 92.82% of the cases the presence of an Ectopic pregnancy was accurately diagnosed 11. 71.90% of the Ectopic pregnancies occurred in the ampule portion of the ovarian tube, of the total number of gestations, 40.95% were tubal abortions and 59.05% were ruptured. The ruptured group occurred more frequently in the islamic portion and interstitial portion of the tube than the aborted group. The aborted group occurred more frequently in the fimbrial extremities of the tube. 12. The blood pressure (systolic) was noted at 119-80mmHg in 81.89% of the total cases. Hemoglobin value was noted at over 8gm/㎗ in 58.57% of the cases. The average blood transfusion was 2.3 pints. 13. In 52.86% of the Ectopic pregnancies the right side of the ovarian tube was affected. The left side of the tube was affected in 47.14% of the cases. 14. 3.33% of the patients were not given an accurate diagnosis. 15. The kinds of operation performed were as follows; Salpingectomy, 41.43%; Adnectomy, 38.57% and Adnectomy with total hysterectomy, 19.05%. 16. The patient mortality rate was significantly small; only 1 case out of 210 died. This patient most likely had a profuse hemorrhage because of a ruptured tube before her admission to the hospital. 17. The patients personal feelings and attitudes must be treated with care. Particularly patients who are concerned about vaginal bleeding or the impossibility of another pregnancy.

• Journal of Chest Surgery
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• 제42권3호
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• pp.331-336
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• 2009

배경: Dubost 등이 1952년에 실시한 신동맥 하부 대동맥류 수술을 시작으로 복부 대동맥류의 근치적인 수술적 치료가 시작되었다. 최근에 경피적 대동맥 스텐트 삽입술의 비약적인 발전으로 외과적 수술이 감소하고는 있으나, 여전히 근치를 위한 치료로 인정되고 있다. 저자들은 지난 6년간 시행한 복부 대동맥류의 수술성적 및 그 예후에 미치는 영향인자에 대해 분석하여 보았다. 대상 및 방법: 2002년 3월부터 2008년 3월까지 복부 대동맥류로 수술 받은 환자 18명을 대상으로 하였다. 수술의 적응은 파열, 60 mm 이상의 최대직경, 크기의 증가, 내과적으로 조절 안되는 고혈압이나 통증이 있는 경우 등이었다. 결과: 환자들의 평균 나이는 $66.6{\pm}9.3$세$(49\sim81)$였고, 남자가 12명(66.7%), 여자가 6명이었다. 신동맥 상부까지 진행된 경우는 6명(33.3%), 장골동맥까지 진행된 경우는 13명(72.2%)이었다. 진단 당시 대동맥이 파열되어 있었던 환자들은 5명(27.8%)이었다. 대동맥의 평균 최대직경은 $72.2{\pm}12.9$ mm ($58\sim109$ mm)였다. 수술은 모두 정중 복부절개를 통한 복강 내 접근으로 시행하였고, 응급수술은 6명의 환자에서 시행하였다. 대동맥 겸자 후 양쪽 하지로 혈류개통이 될 때까지의 허혈시간은 평균 $82{\pm}42$분($35\sim180$분)이었다. 전체 환자 중 3명이 사망하여 전체 사망률은 16.7%였고, 파열된 환자의 사망률은 60%, 파열되지 않은 환자의 사망률은 0%였다. 수술 후 합병증으로는 신부전, 대퇴등 정맥 폐쇄, 창상감염이 각 1예씩 있었다. 생존 환자들은 $34{\pm}26$개월($4\sim90$개월)간의 추적관찰 기간동안 대동맥 내 문제는 없이 장기생존 중이다. 사망에 영향을 주는 인자로는 파열, 응급수술이 의미 있었다(p<0.05). 결론: 파열된 복부대동맥류에 대한 응급수술은 여전히 높은 사망률을 보이나, 파열되지 않은 복부대동맥류의 수술은 비교적 안전하게 진행할 수 있으며 수술 후 생존한 환자는 장기생존을 보인다. 비록 경피적 대동맥 스탠트 삽입술이 최근의 치료 경향이나 종래의 수술방법도 만족할 만 한다.

• Reproductive and Developmental Biology
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• 제36권1호
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• pp.27-32
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• 2012

본 연구는 강원도 영동지방의 7개 시 군(강릉, 동해, 태백, 삼척, 속초, 양양, 고성)의 93개 농가에서 사육 중인 1,655두의 암소의 인공수정에 사용된 한우보증씨수소(KPN, Korean proven bulls number) 정액을 대상으로 인공수정 실패율과 동결정액의 성상 분석에 대해 실시하였다. 암소 인공수정에 사용된 KPN 정액의 인공수정 실패율 범위는 27.6~77.2%로 나타나, 씨수소 간의 인공수정 실패율 차이가 52.9%로 크게 나타났으며, 이중 KPN506이 27.6%로 가장 낮은 인공수정 실패율을, KPN593이 77.2%의 가장 높은 인공수정 실패율을 나타냈다. 또한, KPN과 암소의 인공수정 실패율은 0.2941의 정의 상관관계를 보여 암소의 인공수정에 있어 KPN 정액의 실패율은 상당한 영향을 미치는 것으로 사료된다. 유세포 분석기(flow cytometry)를 이용한 KPN593과 KPN637의 동결정액 성상분석결과에서 인공수정 실패율이 높은 KPN593의 생존율(viability rate)이 30.49%로 KPN637(37.34%)에 비해 유의적으로 낮은 결과를 보였으며($p$<0.05), 유의적인 차이를 보이진 않았지만 첨체 이상율 평가(ruptured acrosome rate)에서도 KPN593 (28.38%)이 KPN637(21.37%) 보다 높은 수치를 나타내었다. 이 결과로 보아 KPN 정액의 번식능력 및 KPN 동결정액의 품질은 암소 인공수정 실패와 매우 밀접한 관련이 있으며, 암소의 수태율 증가를 위해 인공수정 실패율이 높은 KPN은 피해야 하며, 향후 농가 이익을 위해 한우 보증씨 수소의 번식능력과 동결정액의 정확한 성상평가가 이루어져야 할 것으로 사료된다.

• 한국잡초학회지
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• 제12권2호
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• pp.132-143
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• 1992

본(本) 연구(硏究)는 oxyfluorfen 및 bensulfuron 두 화합물간(化合物間)의 상호작용(相互作用)에 의한 상승효과(相乘效果)를 해부학적(解剖學的)으로 구명(究明)하기 위하여 벼와 수종(數種)의 잡초종(雜草種)에 oxyfluorfen 및 bensulfuron을 조합(組合)하여 0, $10^{-6}$ 및 $10^{-4}$ M 농도(濃度)로 만들고 각각 72시간동안 침적처리(沈積處理)한 후 광학현미경하(光學顯微鏡下)에서 ${\times}$40, ${\times}$100 및 ${\times}$400 배율(倍率)로 검경(檢鏡) 촬영(撮影)하였다. 줄기의 표피조직(表皮組織)이나 분열조직(分裂組織)의 형태변화(形態變化)를 검경(檢鏡)한 결과, 두 공시약제에 대하여 벼는 비교적 내성(耐性)을 보여서 형태변화(形態變化)에 큰 차이를 보이지 않았으나 다소간의 세포배열(細胞配列)이나 세포형태변화(細胞形態變化)는 인정이 되었다. 그러나 피는 분열조직(分裂組織)에서의 뒤틀림과 비틀림 현상이 야기되었고 횡단면검경(橫斷面檢鏡)에서는 두 약제(藥劑)에 조합처리(組合處理)로 인한 세포막(細胞膜) 파괴(破壞)나 표피조직(表皮組織)의 파괴(破壞)가 극심(極甚)하였다. 물달개비는 두 약제 모두에 감수성(感受性)이어서 어떤 초종(草種)보다도 측생(側生) shoot의 유도(誘導)와 세포(細胞)의 완벽한 파괴(破壞)가 있었다. 올챙고랭이는 비교적(比較的) 내성(耐性)이 있어서 벼에 유사한 현상을 보였고 올미는 생장억제(生長抑制)와 세포(細胞)의 투명화(透明化), 무핵화(無核化) 및 부규칙배열(不規則配列)이 있었으나 비교적(比較的) 조합처리(組合處理)에 대한 반응(反應)은 내성(耐性)을 보였다. 너도방동사니는 뒤틀림과 무핵화(無核化) 및 막파괴(膜破壞)가 심하였다. 따라서 모든 잡초종(雜草種)에서 두 약제(藥劑)의 조합처리(組合處理)로 인한 상승효과(相乘效果)가 인정되었다.

• Journal of Korean Neurosurgical Society
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• 제63권1호
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• pp.56-68
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• 2020

Objective : To analyze the incidence and treatment trends of hemorrhagic stroke (HS), according to HS subtypes, using nationwide data in Korea from January 2008 to December 2016. Methods : We used data from the national health-claim database provided by the National Health Insurance Service for 2008-2016 using the International Classification of Diseases. The crude incidence and age-standardized incidence of each disease associated with HS, which included intracranial aneurysm (IA), hypertensive intracerebral hemorrhage (ICH), and arteriovenous malformation (AVM), were calculated and additional analysis was conducted according to age and sex. Changes in trends in treatment methods and number of treatments were analyzed for each cerebrovascular disease using the Korean Classification of Diseases procedure codes. Results : In 2016, the total number of newly diagnosed adult patients with HS was 24169, showing a decrease by 7.0% since 2008; the age-standardized incidence of HS was 46.2 per 100000 person-years. The age-standardized incidence of unruptured IA (UIA) in adults was 71.4 per 100000 person-years-increased by 2.6-fold since 2008-while that of ruptured IA (RIA) was 12.6 per 100000 person-years, which had decreased at a rate of 20.3% since 2008. The number of coil embolization (CE) for UIA increased by 3.4-fold over 9 years and exceeded that of clipping since 2008. With respect to RIA, CE increased by 2.0-fold over 9 years and exceeded that of clipping from 2014. As for spontaneous ICH in adults, the age-standardized incidence was 31.3 per 100000 person-years in 2016-decreased by 34.7% since 2008-and 14.6% of patients diagnosed with ICH were treated in 2016, which was not significantly different from the proportion of patients treated since 2008. The age-standardized incidence of unruptured AVM (UAVM) was 2.0 per 100000 person-year in 2016, while that of ruptured AVM (RAVM) was 2.4 per 100000 person-years in 2016, showing a decreasing rate of 17.2% from 2008. The total number of treated patients with AVM declined since 2014. Conclusion : In Korea, age-related cerebral vascular diseases, such as RIA, ICH, and RAVM, demonstrated a declining trend in age-standardized incidence; meanwhile, UIA and UAVM demonstrated an increased trend in both crude incidence and age-standardized incidence for 9 years. The increase in the elderly population, management of hypertension, and development of diagnostic and endovascular techniques appear to have influenced this trend.

• 한국잡초학회지
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• 제17권3호
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• pp.281-287
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• 1997

다양한 재배조건에서 벼와 피의 파종 및 이앙후 7 일째에 oxyfluorfen 유제 0.08kg ai/ha을 경엽처리한 후 그들의 생장 및 해부학적 반응을 조사하고자 온실내 pot시험이 수행되었다. Oxyfluorfen은 피의 지상부, 지상부 신장 및 지상부 생체중을 각 재배조건에서 100% 억제시켰으나 직파벼는 0~64%, 이앙벼는 0~12% 각각 억제시켰다. 초장과 지상부생체중에 있어서 oxyfluorfen은 건답조건(16~33%)보다는 담수조건(53~63%) 에서, 토중파종벼(16~63%)보다는 표면파종벼(34~64%)를 더 억제시켰다. 검경에 의한 해부학적 반응에 있어서 벼의 엽육세포의 부분적 파괴 및 엽신의 두께 감소가 관찰되었고 표피 및 유관속초세포는 큰 변화를 보이지 않았다. 한편 피는 전재배조건에서 표피세포, 엽육세포 및 유관속초세포의 파괴 및 위축 그리고 엽신두께의 유의적인 감소가 있었다. 이러한 해부학적 반응은 담수조건에서 보다 건답조건에서 더 크게 나타났다. oxyfluorfen은 피에 대한 방제는 각 조건에서 완벽하게 방제하였으나 벼에 대한 약해는 피에 비해 상대적으로 작았고 건답조건과 토중파종경우에서 상대적인 안전성을 보였으나 근본적인 약해를 피하기는 어려울 것으로 판단되었다.