• 대한화장품학회지
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• 제48권3호
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• pp.213-223
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• 2022

본 연구에서는 과도한 산화 스트레스에 따른 각종 염증 질환과 피부 노화를 예방하기 위해 수영 지상부(aerial parts of Rumex acetosa L.) 추출물의 항염증, 항산화 효과를 확인하였다. ABTS assay를 시행한 결과 농도 의존적으로 radical 소거능이 증가함을 확인하였다. 활성산소종(reactive oxygen species, ROS) 억제능은 DCF-DA assay를 통하여 확인하였고, 농도 의존적인 ROS 생성억제를 확인하였다. ROS에 따른 세포 핵 손상 억제 효과는 DAPI staining을 통하여 확인하였다. 또한 iNOS, COX-2의 mRNA 발현 수준은 qPCR을 통하여 농도 의존적으로 억제함을 확인하였다. iNOS, COX-2의 단백질 수준을 western blotting을 통해 확인한 결과, iNOS는 모든 농도에서 유의하게 감소하였으며, COX-2는 800 ㎍/mL에서 유의하게 감소하였다. iNOS에 의해 생성된 NO의 생성 억제 효과는 NO assay로 확인하였으며 농도 의존적으로 NO가 감소하였다. 또한, MAPKs 신호전달 경로 중 ERK와 JNK의 인산화를 억제하였다. 따라서 Rumex acetosa L.은 MAPKs 경로를 통한 항염증 효과와 항산화 효과를 보여 항염증 및 항산화 화장품 원료로 사용될 수 있는 가능성이 있다.

• 생약학회지
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• 제42권2호
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• pp.144-148
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• 2011

Rhubarb (Rhei Rhizoma) has been used for the various clinical purposes such as purgative, stomach protective and pain relief for a long time. However, rhubarb in current market has a problem of quality control under which many of rhubarb fail to meet the standard specified in Korean Pharmacopoeia. This study was carried out to validate the method for the evaluation of the quality of five rhubarbs and Rumex species; Rheum palmatum, R. officinale, R. tanguticum, R. franzenbachii, R. undulatum, and Rumex species. The content of sennoside A with five anthraquinones (aloe-emodin, rhein, emodin, chrysophanol and physcion) in five rhubarbs and one Rumex has been performed by using HPLC quantitation analysis. In results, only four samples in Palmata sect. were qualified with sennoside A and those samples were R. officinale and R. tanguticum. Samples of R. palmatum did not meet the standard contents of sennoside A. The contents of anthraquinones in Palmata sect. were two times larger than those in Rhapontica sect. Moreover the content variations of anthraquinones were smaller than those of sennoside A. Thus, anthraquinones can be the key characterizing molecules to control quality of rhubarb.

• Journal of Microbiology and Biotechnology
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• 제30권12호
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• pp.1885-1895
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• 2020

Rumex japonicus Houtt (RJH) is a valuable plant used in traditional medicine to treat several diseases, such as scabies and jaundice. In this study, Jurkat cell growth inhibitory extracts of R. japonicus roots were subjected to bioassay-guided fractionation, resulting in the isolation of three naphthalene derivatives (3-5) along with one anthraquinone (6) and two phenolic compounds (1 and 2). Among these compounds, 2-methoxystypandrone (5) exhibited potent anti-proliferative effects on Jurkat cells. Analysis by flow cytometry confirmed that 2-methoxystypandrone (5) could significantly reduce mitochondrial membrane potential and promote increased levels of mitochondrial reactive oxygen species (ROS), suggesting a strong mitochondrial depolarization effect. Real-time quantitative polymerase chain reaction (qPCR) analysis was also performed, and the results revealed that the accumulation of ROS was caused by reduced mRNA expression levels of heme oxygenase (HO-1), catalase (CAT), glutathione peroxidase (GPx), and superoxide dismutase (SOD). In addition, 2-methoxystypandrone (5) triggered strong apoptosis that was mediated by the arrest of the G0/G1 phase of the cell cycle. Furthermore, 2-methoxystypandrone (5) downregulated p-IκB-α, p-NF-κB p65, Bcl2, and Bcl-xl and upregulated BAX proteins. Taken together, these findings revealed that 2-methoxystypandrone (5) isolated from RJH could potentially serve as an early lead compound for leukemia treatment involving intracellular signaling by increasing mitochondrial ROS and exerting anti-proliferative effects.

• 한국환경복원기술학회지
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• 제13권1호
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• pp.14-23
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• 2010

The vascular plants in the Haksan, Jeonju were listed 394 taxa; 94 families, 260 genera, 339 species, 1 subspecies, 46 varieties and 8 forms. Divided into woody plants were 111 taxa (28.2%) and herbaceous plants were 283 taxa (71.8%). Based on the list of rare plants by the Korea Forest Service; Viola albida (Preservation priority order : No. 202), Korean endemic plants, 6 taxa were recorded; Lespedeza maximowiczii for. tomentella, Indigofera koreana, Weigela subsessilis, etc. Specific plant species by floral region were total 19 taxa (4.8% of all 394 taxa of vascular plants); Wistaria floribunda (Planted species) in class IV, Acer palmatum (Planted species) and Melothrua japonica in class III, Nymphoides indica in class II, 15 taxa (Botrychium virginianum, Hosta capitata, Salix glandulosa, Quercus variabilis, Rhynchosia acuminatifolia, Ilex macropoda, Impatiens nolitangere, Grewia biloba var. parviflora, Vaccinium oldhami and Lonicera praeflorens, etc.) in class I. The naturalized plants in the surveyed sites were 14 families, 30 genera, 32 taxa (Bromus rigidus, Rumex obtusifolius, Chenopodium ficifloium, Amaranthus lividus, Phytolacca americana, Lepidium apetalum, Amorpha fruticosa, Geranium carolinianum, Ailanthus altissima, Euphorbia supina, Oenothera biennis, Ipomoea purpurea, Veronica persica, Bidens frondosa, etc.) and naturalization rate was 8.1% of all 394 taxa of vascular plants. The ecosystem disturbing wild plants, Rumex acetocella, Aster pilosus and Ambrosia artemisiaefolia having manage to designation with Ministry of Environment.

• 환경생물
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• 제38권3호
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• pp.392-403
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• 2020

This study analyzed the distribution characteristics of invasive alien plants on the islands of the Korean Peninsula. Ten species, Rumex acetosella, Sicyos angulatus, Solanum carolinense, Ambrosia artemisiaefolia var. elatior, Ambrosia trifida, Aster pilosus, Eupatorium rugosum, Hypochaeris radicata, Lactuca scariola, and Paspalum distichum were present on 68 islands. These ecosystem-disturbing invasive alien plants appeared extensively on the islands of Gyeonggi province and Jeollanam province. The proportion of the plants on the inhabited islands (41 places, 2.15 species on average) was higher than that on the uninhabited islands (27 places, 1.07 species on average). This means that the distribution of invasive alien plants was closely related to human activity. The distribution of Ambrosia artemisiaefolia var. elatior(32 islands) and Rumex acetosella (31 islands) was the widest, and there were distinct distribution differences according to species. In the island area, the physical environment is poor compared to the mainland, and the native space is limited. Therefore, when invasive alien species enter and settle on the island, the native island plants can be damaged more than those on the mainland. In this regard, the discussion of the distribution of invasive alien plants in the island region can contribute to the conservation of biodiversity in the region.

• 한국환경복원기술학회지
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• 제20권5호
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• pp.15-41
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• 2017

The purpose of this study is to present the basic data for conservation of forest ecosystem by surveying and analysing the flora distributed in Nakdong-Jeongmaek Mountains, Korea. The numbers of flora were 901 taxa including 116 families, 433 genera, 790 species, 4 subspecies, 90 varieties, 15 forms and 2 hybrids. The threatened species was Pedicularis ishidoyana. The rare plants were 33 taxa including Pseudostellaria sylvatica, Cimicifuga heracleifolia var. bifida, Isopyrum mandshuricum, Paeonia japonica, Syringa patula var. kamibayshii, Lilium distichum, Iris odaesanensis and so forth. The Korean endemic plants were 35 taxa including Salix koriyanagi, Thalictrum actaefolium var. brevistylum, Corydalis maculata, Lespedeza maritima, Cirsium setidens, Carex okamotoi and so forth. The specific plants by floristic region were 155 taxa including 55 taxa of grade I, 41 taxa of grade II, 36 taxa of grade III, 18 taxa of grade IV and 5 taxa of grade V. The naturalized plants were 62 taxa including Rumex obtusifolius, Amaranthus lividus, Medicago sativa, Geranium carolinianum, Malva sylvestris var. mauritiana, Foeniculum vulgare, Sonchus oleraceus, Tradescantia reflexa and so forth. The invasive alien plants were 5 taxa including Rumex acetocella, Solanum carolinense, Ambrosia artemisiifolia, Aster pilosus and Lactuca scariola.

• 한국환경복원기술학회지
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• 제8권5호
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• pp.39-46
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• 2005

This study was conducted to investigate the heavy metal accumulation in wild plants. The samples from 5 plant species on 14 sites were taken on the roadside where urban and industrial regions in northern Gyeonggi do. Artemisia princeps var. orientalis, Chenopodium album L. var. centrobrum, Erigeron canadensis L., Rumex crispus L. and Taraxacum platycapum H. Dahlst were taken from different parts of the plants gathered in surveyed sites for analysing. This study classified which species were suitable to accumulators, excluders, or indicators which were provided as Phytoremediation for heavy metals(Cd, Cr, Ni, Pb and Zn) and considered the applicability of that work. 1. The mean accumulation of 6 heavy metals in plants was as follows; Zn> Cu> Cr> Pb> Ni> Cd in rows except for Ni and Pb in Erigeron. 2. The highest heavy metal accumulators were Taraxacum and Artemisia. 3. The comparison of heavy metal accumulations between the tops and roots in the plants was as follows; Zn> Cd> Pb> Ni> Cu> Cr. 4. Comparison of heavy metal accumulations between tops and roots, root parts were higher than the top parts in most of the plants. Especially, in Taraxacum, a ratio was over 1.0 in Cr, Ni, and Zn. Therefore, Taraxacum was an accumulator for 3 heavy metals. And Erigeron, Chenopodium, Rumex, Artemisia were good for excluders which had lower than 1.0.

• 한국응용과학기술학회지
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• 제41권2호
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• pp.159-171
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• 2024

본 연구는 소루쟁이 뿌리 추출물의 유효성 실험을 위해 항산화 활성 및 항균 효능을 확인하고 제형 안정성을 확인하였다. 항산화 활성으로는 DPPH radical scavenging, FRAP activity, ABTS⁺ radical scavenging, SOD-like activity를 진행하였으며 항균 활성 평가는 Staphylococcus epidermidis, Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Candida albicans 균주에 대해 생육저해환과 최소저해농도를 평가하였다. 또한 소루쟁이 뿌리 추출물을 함유한 스킨을 21일 동안 pH, 온도, 일광에 대한 경시 변화를 확인하였다. 항산화 평가 결과 0.0625-1mg/mL 농도에서 농도 의존적으로 활성이 증가하는 것을 확인할 수 있었다. 생육저해환의 경우 100mg/mL 농도에서 각 균의 생육저해환이 10.45±0.34, 9.77±0.59, 9.92±0.22, 10.08±0.12로 대조군인 Methyl paraben에 비해 우수한 항균력을 확인할 수 있었고 최소저해농도의 경우 100mg/mL 농도에서 S. aureus, E. coli에 대한 항균력을 확인하였다. 스킨의 pH 농도가 4.0, 6.0, 7.0에서 흡광도의 변화가 미미하였고, 4℃, 25℃, 40℃에서 온도가 높아질수록 변색되는 것을 확인하였다. 또한 스킨을 일광과 실온에서 보관했을 때 일광에서 변색이 일어난 것을 보아 소루쟁이 뿌리 추출물을 함유한 화장품은 차광하여 저온 보관하면 변색을 방지 할 수 있을 것으로 추측된다. 본 연구 결과를 종합하였을 때 소루쟁이 뿌리 추출물은 항산화, 항균 활성을 기대할 수 있는 화장품 원료로 이용 가치가 높을 것으로 사료된다.

• Asian-Australasian Journal of Animal Sciences
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• 제4권3호
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• pp.245-250
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• 1991

Analysis of the characteristics and the grouping of the species of sown and weeds in artificial pastures was studied applying the principal component analysis method. Presency and coverage of six sown species and fifteen weed species which occurred in pastures of under-grazing and optimumgrazing were subject to analysis. From field survey, species were divided into three groups: the group A included five species such as Festuca arundinacea, Lolium perenne and Dactylis glomerata, etc., the group B included eleven species such as Polygonum longisetum, Agrostis alba and Rumex obtusifolius, etc., and the group C included five species such as Miscanthus sinensis, Rubus palmatus and Artemisia princeps, etc. The group A species corresponded to good pasture conditions and management. On the contrary, the group C species occurred in poor pasture conditions with inadequate management. The group B species corresponded to intermediate pasture conditions and management. Interrelated pair species co-existing and species non-co-existing were discovered. Factor loading as negative for the group A species. positive for the group C species and positive but lower than the group C species for the group B species. From these results it is concluded that the principal component analysis seems to one of the useful tools for the analysis of characteristics of species and the diagnosis of sown pasture vegetation, although further studies are required to get more general information about species characteristics.

• 환경생물
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• 제37권2호
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• pp.144-154
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• 2019

경주시 사적지, 도시공원지역, 그리고 하천 86개소의 현지조사를 통하여 귀화식물을 조사한 결과 21과 59속 78종 1아종 5변종으로 총 84분류군으로 조사되었다. 이중 사적지는 68분류군, 근린공원 43분류군, 하천 59분류군, 소공원 42분류군 등으로 나타났다. 출현식물 중 널리 분포하나 개체수는 많지 않은 귀화도 3등급 분류군이 31.0%, 널리 분포하고 개체수도 많은 5등급이 29.8%, 국지적으로 분포하고 개체수도 많지 않은 분류군인 2등급이 20.2% 등으로 나타났다. 생태계교란식물은 미국쑥부쟁이, 가시상추, 애기수영 등 7분류군으로 가시상추는 41.9%로 가장 빈번하게 출현하였고, 미국쑥부쟁이는 34.9%로 하천변에서, 애기수영은 25.6%로 사적지나 소공원 일원에서 빈번하게 출현하였다. 생태계교란식물의 확산을 방지하기 위해서는 지속적인 모니터링이 필요하며, 특히, 정착초기에 물리적 제거나 토양의 대체 등 관리 계획이 필요하다.