• Clinical and Experimental Reproductive Medicine
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• 제50권1호
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• pp.34-43
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• 2023

Objective: The aim of this study was to investigate the effect of royal jelly (RJ), a powerful natural antioxidant, on cyclophosphamide-induced ovarian damage. Methods: Thirty-two Wistar albino rats were divided into four groups. Oral treatment was administered to all rats for 16 days after a single intraperitoneal injection. The control group received intraperitoneal and oral saline; the RJ group received intraperitoneal saline and 100 mg/kg/day oral RJ; the cyclophosphamide group received intraperitoneal 100 mg/kg cyclophosphamide and oral saline; and the treatment group received intraperitoneal 100 mg/kg cyclophosphamide and 100 mg/kg/day oral RJ. The groups were compared in terms of ovarian reserve tests and histopathological changes in the ovary and uterus. Results: All follicle counts were higher in the treatment group than in the cyclophosphamide group. The increase in the number of preantral follicles (p=0.001) and the decrease in the number of atretic follicles (p=0.004) were statistically significant. RJ treatment significantly improved follicular degeneration and cortical fibrosis in the ovary and epithelial and gland degeneration in the uterus due to cyclophosphamide toxicity. Conclusion: According to these results, RJ reduces cyclophosphamide-related ovarian and endometrial damage in rats. For this reason, it should be further investigated to determine its effects on reproductive function.

• 한국의사학회지
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• 제32권2호
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• pp.91-104
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• 2019

In this paper, the clinical records of Queen Inmok has been studied and the impact of historical events on her life has been analyzed. This paper has extracted her medical records during King Seonjo's and King Injo's period from the Annals and the Daily Records of Royal Secretariat of Joseon Dynasty, and then contemplated their medical implications consulting Donguibogam as a primary reference. Queen Inmok had been yang deficiency after national mourning. But suffering a series of misfortunes, she was ill with fire-heat (火熱) syndrome and finally passed away suffering from high fever, frequent diarrhea and profuse sweating. At that time, practitioners abused cold therapy following Jin Yuan Sia Jia (金元四大家), so they missed Queen Inmok's yang deficiency.

• Korean Journal of Acupuncture
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• 제28권2호
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• pp.77-86
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• 2011

Objectives : This study is on the acupuncture and moxibustion treatment records of King Hyeonjong, classified according to diseases and chronology. Methods : Records on the acupuncture and moxibustion treatment of King Hyeonjong have been extracted from the web database of "The Daily Records of Royal Secretariat of Chosun Dynasty". First, all articles containing the keywords 'Yakbang (藥房)' and 'Euigwan (醫官)' have been extracted. Then, those during King Hyeonjong's reign have been rearranged in chronological order. Among these records, those regarding acupuncture and moxibustion have been used in this paper. Results : King Hyeonjong was mostly treated on eye diseases, musculoskeletal system disorders, deficient source qi, and tumor. Acupuncture treatment was preferred for eye diseases, and moxibustion treatment for musculoskeletal disorders. Medicine was used 50 times, acupuncture 4 times, and moxibustion 14 times to treat source qi deficiency, showing that acupuncture and moxibustion treatments were used for clear deficiency syndrome. Only on the case of tumor, the number of acupuncture treatments was bigger than that of medicine treatments. Conclusions : In the early days of his reign, King Hyeonjong suffered from hypochondria, as compared to source qi deficiency and septicemia during later days. He received frequent acupuncture and moxibustion treatments, and he especially preferred those treatments for eye diseases and musculoskeletal disorders.

• 한국의사학회지
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• 제22권2호
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• pp.23-31
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• 2009

Jecheon is a place of Korean Medicine with many historical characters, medical tales and cultures. One of the most renowned characters is Lee Gong Gi(李公沂), a 扈聖功臣 (title given to the 86 people that escorted king Seonjo during the Japanese Invasion of Korea in 1592) at the level of Huh Jun(許浚) and famous royal physician of Joseon who served King Seonjo and reached the highest position of chief physician. He was recognized for his talent as a royal physician and was conferred with the title of 扈聖功臣 Rank 3 after attending on King Seonjo during the Japanese Invasion of Korea in 1592. Despite the fact that he was a renowned man of medicine, he didn't get as much attention as 許浚 or Yang Ye Soo(楊禮壽) because documents on his work had not been studied. In this study, the author was able to study Lee Gong Gi(李公沂) based on documents such as "朝鮮王朝實錄(True Record of the Joseon Dynasty)", "內醫院先生案(Naeeuiwonseonsengan)", "醫科先生案(Euigwaseonsengan)" and on "避難行錄(Pinanhengrok)" by Yakpo Jeongtak (1526~1605) who was a govemmental pharmacist at the time of Japanese Invasion of Korea in 1592. According to "內醫院先生案" and "醫科先生案", Lee Gong Gi's son Lee Young Nam followed his father's footsteps and became the chief royal pharmacist and 崇政大夫(one of the governmental titles of Joseon Dynasty). As for Jecheon's Korean medical traditions, many forms of medical tales and cultures are preserved such as the tales of Neokgogae, Mountain Ami's medical water cave, Otmaru and Seonsimgol. These tales are divided into various types of great doctors, medical herbs and devoted sons and have been passed down With the origin of traditional medicine still intact. Moreover, ancient documents and artifacts on Traditional Korean Medicine that reflect the area's medical culture have been discovered. Not only is Jecheon a place of medical culture but along with Jecheon Drug Market it also carries on the tradition of medical herbs production and possesses the largest new medical herbs market in Korea. In conclusion, Jecheon is a traditional place of Korean Medicine with many medical cultures and characters from a unique history.

• 한국한의학연구원논문집
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• 제14권2호
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• pp.1-10
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• 2008

Noh Jungrye(盧重禮) can be cited as an representative royal doctor of early Chosun dynasty. He collaborated in the development of korean medicine out of the influence of chinese medicine. He made an systematical approach on supply and propagation of The Native Herb Medicine(鄕藥) which promoted the independence of Korean medicine. The edition of "HyangYakJibSungBang(鄕藥集成方)"(Compendium of Prescriptions from the Countryside) was the result of this effort establishing the originality of Korean medicine. He also strengthened in the medical support new born child editing "TaeSanYoRok(胎産要錄)" as their mortal rate was high in that time. In social-political aspect, being appointed in Dangsanggwan(堂上官) as a doctor, was controversial as even after his death this discussion kept on. On the other hand this designation prompt other doctors to devote in Korean medicine.

• 대한한의학원전학회지
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• 제30권3호
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• pp.11-40
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• 2017

Purpose : The purpose of this article is to make a clarification that Hwang Doyeon(黃度淵) was a official doctor(醫官) who even served as royal doctor(御醫), rather than merely a general doctor who worked in the private sector. The article also attempts to give a new perspective on the medical history about the late period of Joseon(朝鮮) Dynasty. Methods : In researching Hwang Doyeon's master work, the Gains and Losses of Medical Orthodoxy(醫宗損益), the article looks at his clinical medicines. Analyzing the historical records, the article makes an assumption that Hwang Doyeon and Hwang Dosoon(黃道淳), who was selected as an officer to discuss medicine with other medical officers(議藥同參), are the identical person. On this assumption, the article tries to reinterpret the medicine during the later Joseon Dynasty period. Result & Conclusion : The records, including the royal medical treatment records of the Gains and Losses of Medical Orthodoxy, the Daily Records of Royal Secretariat(承政院日記), the genealogy of Changwon Hwangs(昌原黃氏世譜), academic paper and government documents released posthumously, demonstrated that Hwang Doyeon and Hwang Dosoon are the same person. If so, we can have new historical interpretation about medical history of late Joseon Dynasty. First, during the late of Joseon Dynasty, there was an official and active medical knowledge interaction between government and private sector. Second, the Joseon's medicine has been established its own medical system based on the Treasured Mirror of Eastern Medicine(東醫寶鑑), trying to cope with cholera and other contemporary epidemics without relying on Chinese warm disease(溫病) medicine. Third, the Compilation of Formulas and Medicinals(方藥合編), is regarded not only as a must-read medical reading for medical doctors, also playing an important role on popularization of Korean medical knowledge.

• 한국임상수의학회지
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• 제30권5호
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• pp.390-393
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• 2013

폐염전으로 진단한 소형견 4 마리의 흉부 방사선 사진 및 컴퓨터단층촬영 (CT) 영상을 평가하였다. 흉수 및 폐염전이 발생한 폐엽의 밀도 증가는 4 마리 환자의 흉부 방사선 사진 및 CT 영상에서 모두 확인되었다. 폐염전이 발생한 기시부에서의 기관지의 협착/허탈은 CT 영상을 통해 4 마리의 개에서 모두 확인된 반면, 흉부 방사선 사진에서는 오직 1 마리의 환자에서만 확인되었다. 폐포성 폐기종 패턴 (vesicular emphysema pattern) 역시, CT 영상을 통해 4 마리의 환자에서 모두 확인된 반면, 흉부 방사선 사진에서는 3 마리에서 관찰되었다. 폐염전의 특이소견은 폐포성 폐기종 패턴과 폐염전이 발생한 폐엽 기시부의 기관지의 협착/허탈이며, 이 소견은 흉부 방사선 사진보다 CT 영상을 통해 좀 더 용이하고 빈번하게 확인되었다.

• 한국한의학연구원논문집
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• 제14권3호
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• pp.11-22
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• 2008

The prime minister(樞密相公) Choi jongjun writes"Eouichwaryobang(御醫撮要方)"A.D. 1226 that is a Goryeo Period (A.D.$918{\sim}1392$). But today that has vanished, now. Inspite of the important worth of that book in Korea Traditional Medicine, there is no study about writer. So I research all the historical source about him. And I confront a historical source with the era for making a chronological table of Choi jongjun. I beliebe this survey make a great contribution towards the historical research of KTM. Now to conclude, In A.D. 1226, Choi Jongjun was Jung chuwonbusa(中樞院副使) or Chumseowonsa(簽書院事).

• The Korean Journal of Physiology
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• 제30권2호
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• pp.187-195
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• 1996

• 대한생식의학회:학술대회논문집
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• 대한불임학회 1997년도 제34차 추계 학술대회
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• pp.9-9
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• 1997