• Korean Journal of Clinical Laboratory Science
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• v.50 no.4
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• pp.375-381
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• 2018

Cytogenetic analysis plays an important role in examinations of a variety of human disorders. Over the years, cytogenetic analysis has evolved to a great extent and become a part of routine laboratory testing; the analysis provides significant diagnostic and prognostic results for human diseases. Microarray in conjunction with molecular cytogenetics and conventional chromosome analysis has transformed the outcomes of clinical cytogenetics. The advantages of microarray technologies have become obvious to the medical and laboratory community involved in genetic diagnosis, resulting in greatly improved visualization and validation capabilities. This article reviews how the field is moving away from conventional cytogenetics towards molecular approaches for the identification of pathogenic genomic imbalances and discusses practical considerations for the routine implementation of these technologies in genetic diagnosis.

• Journal of the Institute of Electronics Engineers of Korea SC
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• v.48 no.1
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• pp.1-8
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• 2011

The accuracy of MR sensor-based electronic compass is influenced by the temperature drift and DC offset of the MR sensor and the OP-amp, the magnetic distortion of nearby magnetic materials, and the compass tilt We design the 3-axis MR sensor and accelerometers-based electronic compass which is compensated by the set/reset pulse switching method on the temperature drift and DC offset, by the execution of hard-iron calibration routine on the magnetic distortion, and by the execution of the Euler rotational equation on the compass tilt. We qualitatively analyze the measured azimuth error on the execution of sensitivity calibration routine which is the normalization process on the different sensitivity of each MR sensor and the different gain of each op-amps. This compensation and analytic result make us design the one degree accuracy electronic compass.

• Nuclear Engineering and Technology
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• v.44 no.2
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• pp.151-160
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• 2012

The advantages for using Monte Carlo methods to analyze full-core reactor configurations include essentially exact representation of geometry and physical phenomena that are important for reactor analysis. But this substantial advantage comes at a substantial cost because of the computational burden, both in terms of memory demand and computational time. This paper focuses on the challenges facing full-core Monte Carlo for keff calculations and the prospects for Monte Carlo becoming a routine tool for reactor analysis.

• Journal of Oriental Neuropsychiatry
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• v.26 no.4
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• pp.383-406
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• 2015

Objectives: People with tension-type headache generally take pain relievers, but long term dependency causes problems as well as side effects. The present study aimed to provide clinical evidence of herbal medicine for tension-type headache by systematic review of randomized controlled trials on the effect of herbal medicine for tension-type headache. Methods: Randomized or quasi-randomized controlled trials that verified effects of herbal medicine intervention on patients with tension-type headache were included in the study. A literature search of English, Japanese, Chinese, Korean databases was performed. The selected literature were assessed by Jadad scale and Risk of Bias. Results: Herein, 40 reports were selected from a total of 157. Meta-analyses of 2 trials indicated that the effective rate was significantly higher in the herbal medicine treatment group, as compared to the placebo control (risk ratio: 1.49, 95% confidence interval (CI): 1.23 to 1.80, p<0.0001, I²=0%). Four trials that compared herbal medicine with routine care with routine care only group showed a significantly higher effective rate of benefits for herbal medicine with routine care, as compared to routine care only (RR: 1.57, 95% CI: 1.18 to 2.10, p=0.002, I²=0%). Conclusions: The effective rate was significantly higher than control and adverse events were less in the treatment group. Pattern analysis (辨證) indicated that the studies on wind-fire pattern (風火證) were highest. Yougeun-bang (柔筋方) in prescription and Paeoniae Radix Alba (白芍藥) in medicinal herbs were most used. This finding could be widely utilized in future clinical practice and form the basis for the development of clinical practice guidelines in advance.

• Toxicological Research
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• v.8 no.1
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• pp.144-156
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• 1992

The residue of drug in foods of animal origin has increasingly become of interest to the entire livestock industry as growing consumer health concerns. The current overvie of feed additives and veterinary drugs used in Japan and their residual analysis has been reviewed. High performance liquid chromatographic technique(HPLC) with various detectors can be expected to be successfully applied for the routine analysis of residual feed additives and veterinary drugs including anabolic agents in livestock products.

• Asia pacific journal of information systems
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• v.15 no.4
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• pp.109-133
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• 2005

The purpose of this study is to develop and validate a model of firm's IT capability based on IT resources such as IT infrastructure, IT personnel, and IT routine. To do this, the study defined IT capability as a third-order factor model and identified three conceptual dimensions of IT capability: IT infrastructure flexibility, IT personnel expertise, IT resource management capability, IT resource management capability indicates a capacity generated by IT routines, a new IT resource type identified in this study. The validity of the proposed model is evaluated with 243 firm level data using LISREL. The results of confirmatory factor analysis(CFA) demonstrated that the model is highly reliable and valid. Additionally, it was found that IT routines have a high potential as a new IT resource category.

• The Journal of the Korean dental association
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• v.36 no.2 s.345
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• pp.135-143
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• 1998

Cephalogram is one of the most important tool in researching growth and development of craniofacial area, orthodontic diagnosis and treatment planning. But its inherent distortion of actual length and angles during projecting three dimensional object to two dimensional plane might cause errors in quantitative analysis of shape and size. three dimensional high quality images can be obtained using computerized tomogram and have reported in literatures. Considering its expenses and amount of exposure to radiation, limitations still remain to be solved in its application to routine practice. construction of three dimensional image using principle of orientator can be obtained by biplanar stereoradiography. Theoretically two images, lateral and P-A can be used to construct three dimensional image provided that those are taken at same time by two different focal spots. As two images(lateral and P-A) obtained by conventional cephalogram have different head posture, those need compensation to construct three dimensional images. This study introduced principle of computerized head posture compensation and showed that conventional cephalogram could be used to construct three dimensional image and could be applied to routine orthodontic practice.

• KIEE International Transaction on Electrical Machinery and Energy Conversion Systems
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• v.3B no.2
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• pp.67-73
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• 2003

In this paper, the impedance of a piezoelectric transducer is calculated using the three-dimensional finite element method. The validity of numerical routine is confirmed experimentally. Using this numerical routine, the effects of material coefficients on piezoelectric actuators characteristics are analyzed. The material constants, which make significant effects, are selected and the relations between material constants are studied. Using these processes, three variables of material constants for a piezoelectric transducer are selected and the design sensitivity method is adopted as an inversion scheme. The validity of the inversion scheme for a piezoelectric transducer is confirmed by applying the proposed method to the sample piezoelectric transducer.

• Proceedings of the Korean Society for Technology of Plasticity Conference
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• 1997.10a
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• pp.164-167
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• 1997

The die wear is one of the main factors affecting die accuracy and tool lifetime. It is desired to reduce die wear by developing simulation method to predict wear based on process parameters, and then optimize the process. Therefore, this paper describes disign methodology of preform for minimizing wear of finisher die in multi-stage cold forging processes. The finite element method is combined with the routine of wear prediction and the cold forging processes. The finite element method is combined with the routine of wear prediction and the cold forging process is analyzed. In order to obtain preform to minimize die wear, the FPS algorithm is applied and the optimal preform shape is found from iterative deformation analysis and wear calculation.

• Proceedings of the KSR Conference
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• 2006.11b
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• pp.43-49
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• 2006

To design railway vehicles to ensure comfortable running, ride comfort of human exposed on vibrating carbody should be considered. Also, to improve ride comfort for passenger coach, many factors should be analysed and evaluated. There are many factors as suspension characteristics of railway vehicle, track characteristics to run etc. In this paper, passenger coach sujected to test on specific routine were evaluated using test results. Test routine were divided by 13 sections to analyse more detail. And the characteristics of every section were analysed distributions of radius curves, tunnel and bridge which could give impact to ride comfort. The evaluation of ride comfort were accomplished by UIC and ISO methods.