• Title/Summary/Keyword: Routine analysis

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Determination of Taurine in Preparations by Amino Acid Autoanalyzer (아미노산 분석기에 의한 제제중 Taurine의 분리 정량에 관한 연구)

  • 박만기;한달수
    • YAKHAK HOEJI
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    • v.28 no.1
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    • pp.21-23
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    • 1984
  • High performance amino acid analyzing method has been developed for the routine analysis of taurine in preparations. Ion-exchange resin #2619 Hitachi Custom Ion-Exchange Resin, $2.6(I.D.){\times}150$(length)mm was used as column, buffer I, pH 3.3 as mobile phase. The retention time of taurine was 7 minutes. Calibration curve by peak height for standard taurine was linear from 2.5ppm to 25ppm. The reproducibility showed relative standard deviation $\pm$1.9% when analyzed 10 times for standard solution. The samples could be continuously analyzed without regenerating the resin between samples. Five samples were applied to column every 12 min. and then the resin was regenerated for 30 min. during one analyzing cycle time, 90 min. The automatic amino acid analyzer has made it possible to assay multiple samples in a relatively short period of time using the analytical magnetic program card. The high sensitivity and specificity of the analytical column of the automatic amino acid analyzer permits the routine analysis of taurine in preparations.

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Analyses of phenolics in cigarette smoke by GC-MS with the multiple ion selction technique

  • Park, Jeen-Woo
    • Archives of Pharmacal Research
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    • v.5 no.2
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    • pp.71-77
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    • 1982
  • Improvements in the analytical methodology used in the gas chromatographic/mass spectral analysis of phenolic compounds from cigarette smoke are described. For the direct analysis of crude samples, pyridine extraction and the glass capillary column GC was used for the separation of phenolics as trimethylsilyl derivativatives. The separations of cigarette smoke on Carbowax 20M and SE-54 wall coated open tubular columns are given. Improved methodology for the routine quantitation of the identified components using the computer-controlled multiple ion selection technique of MS presented. Considerations pertaining to routine analyses of a multitude of complex smoke samples are also discussed.

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Determination of Hydrogen Peroxide Concentration by Portable Near-Infrared (NIR) System (근적외분광분석법을 이용한 과산화수소의 농도 측정)

  • 임현량;우영아;장수현;김경미;김효진
    • YAKHAK HOEJI
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    • v.46 no.5
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    • pp.324-330
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    • 2002
  • This experiment was carried out to determine non-destructively the hydrogen peroxide concentration of 3% antiseptic hydrogen peroxide solutions by portable near-infrared (NIR) system. Hydrogen peroxide standards were prepared ranging from 0 to 25.6 w/w% and the NIR spectra of hydrogen peroxide standard solutions were collected by using a quartz cell in 1 mm pathlength. We found the variation of absorbance band due to OH vibration of hydrogen peroxide depending on the concentration around 1400 nm in the second derivatives spectra. Partial least square regression (PLSR) and multilinear regression (MLR) were explored to develop a calibration model over the spectral range 1100-1720 nm. The model using PLSR was better than that using MLR. The calibration showed good results with a standard error of prediction (SEP) of 0.16%. In order to validate the developed calibration model, routine analyses were performed using commercial antiseptic hydrogen peroxide solutions. The hydrogen peroxide values from the NIR calibration model were compared with the values from a redox titration method. The NIR routine analyses results showed good correlation with those of the redox titration method. This study showed that the rapid and non-destructive determination of hydrogen peroxide in the antiseptic solution was successfully performed by portable NIR system without very harmful solvents.

Developement and application of Statistical Hydrofracturing Data Processing Program (통계적 접근법에 의한 수압파쇄 자료해석용 전산 프로그램 개발 및 적용)

  • 류동우;최성웅;이희근
    • Tunnel and Underground Space
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    • v.6 no.3
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    • pp.209-222
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    • 1996
  • Shut-in pressure, reopenting pressure and fracture orientation are very important parameters to be evaluated precisely in in-situ stress measurement by hydraulic fracturing. Graphical methods on pressure-time curves have been conventionally used, even though these are seriously dependent on subjectivity of interpreters. So there have been many demands on new method to objectivity in determining parameters. We have developed integrated hydrofracturing data processing program (HYDFRAC), based on nonlinear regression analysis and can be invoked under the Window graphical user interface. HYDFRAC consiste of three routines, that is shut-in pressure routine, reopening pressure routine, and fracture delineation routine. Each of routines include independent modules according to parameter determination methods. Its application to field tests ensured both objectivity and facility in determining of hydraulic fracturing parameters. Determining shut-in pressures at each pressurization cycles, we adopted the exponential pressure-decay method(EPD method), the bilinear pressure-decay-rate method (PDR method), and the tangent intersection method in order to find the pressurization-cyclic tendency of shut-in pressures. The estimated pressure by PDR method exists in the range of the upper and lower values by EPD method, and lies near to the upper value more than the lower. Being the pressurization cycle increased, the range of upper and lower limits come to be stabilized gradually. By graphical superposition method and bilinear pressure-accumulated volume method, reopening pressures were determined. Vertical and inclined fracture attitudes were determined by applying the directional statistics and sinusoidal curve fitting, respectively. The results of evaluation of hydrofracturing parameters showed that statistical methods could enhance the objectivity better than graphical methods.

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Estimating the Impact of Automation and Globalization on Manufacturing Employment using Regional Labor Market Analysis (지역별 제조업 고용변화에 대한 자동화와 세계화의 영향)

  • Cho, Sungchul
    • Journal of the Economic Geographical Society of Korea
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    • v.22 no.3
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    • pp.274-290
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    • 2019
  • This article links the change in regional manufacturing employment in Korea after the financial crisis to the geography of technological and trade shocks. We conceptualize the trade shock as the rapid growth in Korean imports from and exports to China and ASEAN countries. We then measure the exposure to technological shocks as the degree to which regions are specialized in routine tasks, which are susceptible to automation technologies. Results show that local labor markets specialized in routine tasks experience significant falls in manufacturing employment. Regions whose industrial structure exposes them to rising import competition experience sharp drop in manufacturing employment. We also found that export plays a major role in explaining the growth of regional manufacturing employment.

A Low-Cost Approach for Path Programming of Terrestrial Drones on a Construction Site

  • Kim, Jeffrey;Craig, James
    • International conference on construction engineering and project management
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    • 2022.06a
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    • pp.319-327
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    • 2022
  • Robots for construction sites, although not deeply widespread, are finding applications in the duties of project monitoring, material movement, documentation, security, and simple repetitive construction-related tasks. A significant shortcoming in the use of robots is the complexity involved in programming and re-programming an automation routine. Robotic programming is not an expected skill set of the traditional construction industry professional. Therefore, this research seeks to deliver a low-cost approach toward re-programming that does not involve a programmer's skill set. The researchers in this study examined an approach toward programming a terrestrial-based drone so that it follows a taped path. By doing so, if an alternative path is required, programmers would not be needed to re-program any part of the automated routine. Changing the path of the drone simply requires removing the tape and placing a different path - ideally simplifying the process and quickly allowing practitioners to implement a new automated routine. Python programming scripts were used with a DJI Robomaster EP Core drone, and a terrain navigation assessment was conducted. The study examined the pass/fail rates for a series of trial run over different terrains. The analysis of this data along with video recording for each trial run allowed the researchers to conclude that the accuracy of the tape follow technique was predictable on each of the terrain surfaces. The accuracy and predictability inform a non-coding construction practitioner of the optimal placement of the taped path. This paper further presents limitations and suggestions for some possible extended research options for this study.

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Improving Diagnostic Performance of MRI for Temporal Lobe Epilepsy With Deep Learning-Based Image Reconstruction in Patients With Suspected Focal Epilepsy

  • Pae Sun Suh;Ji Eun Park;Yun Hwa Roh;Seonok Kim;Mina Jung;Yong Seo Koo;Sang-Ahm Lee;Yangsean Choi;Ho Sung Kim
    • Korean Journal of Radiology
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    • v.25 no.4
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    • pp.374-383
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    • 2024
  • Objective: To evaluate the diagnostic performance and image quality of 1.5-mm slice thickness MRI with deep learningbased image reconstruction (1.5-mm MRI + DLR) compared to routine 3-mm slice thickness MRI (routine MRI) and 1.5-mm slice thickness MRI without DLR (1.5-mm MRI without DLR) for evaluating temporal lobe epilepsy (TLE). Materials and Methods: This retrospective study included 117 MR image sets comprising 1.5-mm MRI + DLR, 1.5-mm MRI without DLR, and routine MRI from 117 consecutive patients (mean age, 41 years; 61 female; 34 patients with TLE and 83 without TLE). Two neuroradiologists evaluated the presence of hippocampal or temporal lobe lesions, volume loss, signal abnormalities, loss of internal structure of the hippocampus, and lesion conspicuity in the temporal lobe. Reference standards for TLE were independently constructed by neurologists using clinical and radiological findings. Subjective image quality, signal-to-noise ratio (SNR), and contrast-to-noise ratio (CNR) were analyzed. Performance in diagnosing TLE, lesion findings, and image quality were compared among the three protocols. Results: The pooled sensitivity of 1.5-mm MRI + DLR (91.2%) for diagnosing TLE was higher than that of routine MRI (72.1%, P < 0.001). In the subgroup analysis, 1.5-mm MRI + DLR showed higher sensitivity for hippocampal lesions than routine MRI (92.7% vs. 75.0%, P = 0.001), with improved depiction of hippocampal T2 high signal intensity change (P = 0.016) and loss of internal structure (P < 0.001). However, the pooled specificity of 1.5-mm MRI + DLR (76.5%) was lower than that of routine MRI (89.2%, P = 0.004). Compared with 1.5-mm MRI without DLR, 1.5-mm MRI + DLR resulted in significantly improved pooled accuracy (91.2% vs. 73.1%, P = 0.010), image quality, SNR, and CNR (all, P < 0.001). Conclusion: The use of 1.5-mm MRI + DLR enhanced the performance of MRI in diagnosing TLE, particularly in hippocampal evaluation, because of improved depiction of hippocampal abnormalities and enhanced image quality.

The Development and Evaluation of Sidestream Smoke Collecting Apparatus Compatible for Linear Smoking Machine (다채널 선형자동흡연장치 부착형 부류연 포집장치의 개발과 평가)

  • Kim Hyo-Keum;Hwang Keon- Jung;Ji Sang-Un;Lee John-Tae;Rhee Moon-Soo
    • Journal of the Korean Society of Tobacco Science
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    • v.27 no.1 s.53
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    • pp.120-126
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    • 2005
  • The Fishtail Chimney system mounted on 1 channel smoking machine is not appropriate for the routine analysis of sidestream smoke, because of its low repeatability and very long time required for smoke collection. To overcome this inconvenience, we developed a new sidestream smoke collecting apparatus compatible for 8 channel linear smoking machine. An electric motor driven stroke and automatic control system were adopted in this device to maximize convenience and efficiency of its operation. Also, we carried out the international collaborative study on monitoring sidestream smoke analysis to test the performance of this system. From the statistical analysis of the data obtained in our laboratory and other participating labs, it has been indicated that the newly developed sidestream smoke collection apparatus could be applicable to the routine analysis of sidestream smoke.

Multimodal Digital Photographic Imaging System for Total Diagnostic Analysis of Skin Lesions: DermaVision-Pro (다모드 디지털 사진 영상 시스템을 이용한 피부 손상의 진단적 분석에 대한 연구 : DermaVision-Pro)

  • Bae, Young-Woo;Kim, Eun-Ji;Jung, Byung-Jo
    • Proceedings of the KIEE Conference
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    • 2008.10b
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    • pp.153-154
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    • 2008
  • Digital photographic analysis is currently considered as a routine procedure in clinic because periodic follow-up examinations can provide meaningful information for diagnosis. However, it is impractical to separately evaluate all suspicious lesions with conventional digital photographic systems, which have inconsistent characteristics of the environmental conditions. To address the issue, it is necessary for total diagnostic evaluation in clinic to integrate conventional systems. Previously, a multimodal digital photographic imaging system, which provides a conventional color image, parallel and cross polarization color images and a fluorescent color image, was developed for objective evaluation of facial skin lesions. Based on our previous study, we introduce a commercial product, "DermaVision-PRO," for routine use in clinical application in dermatology. We characterize the system and describe the image analysis methods for objective evaluation of skin lesions. In order to demonstrate the validity of the system in dermatology, sample images were obtained from subjects with various skin disorders, and image analysis methods were applied for objective evaluation of those lesions.

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