• 한국결정성장학회지
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• 제8권3호
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• pp.454-462
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• 1998

AUC 침전과정중 AUC 입차를 둥글게 제조하는 조건과 기구를 조사하였다. 둥근 AUC 제조는 교반기를 이용한 내부순환 시는 불가능했으나 펌프를 사용한 외부순환 시는 가능했다. 둥근 AUC 제조속도($dn_p$/dt)는 침전조건인 슬러리 밀도($M_t:U/l)$, 슬러리 회전율($T_o$:turn-over ratio), 임펠러 속도(U:Impelle tip velocity)에 비례하여 관계식을 $ dn_p/dt{\propto}M_t{\cdot}T_o{\cdot}U^2$로 표기할 수 있었으며, 이 속도식은 실험결과와 정성적으로 일치하였다. 그리고 두 개의 둥근 AUC 제조 기구가 제시되었는데, 하나는 균일형성기구이고 다른 하나는 etch-pit 형성기구이다. 전자는 AUC 침전과정에서 초기에 발생되고 후자는 침전과정 말기에 발생되는 것으로 확인되었다.

• KSBB Journal
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• 제22권5호
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• pp.282-287
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• 2007

The antiviral mechanism of KT5720 is known to inhibit the cAMP-dependent protein kinase (PKA), on the VSV infection in BHK-21 cell cultures. The virus inducted CPE (cell rounding) was almost completely suppressed by KT5720 at 5 uM. The inhibitor, however, did not affect the replication of the virus and the synthesis of viral macromolecules. Immunological studies showed the viral matrix (M) protein displayed intimate association with the cytoskeletal components and probably the cell rounding. KT5720, did not block the cytoskeletal disruption, while the cell rounding was suppressed. These observations suggest that the interaction between the viral M protein and the cytoskeletal components may not be enough to cause the morphological change of the cell. And, the KT5720-sensitive function may be involved in developing the VSV-induced CPE, but not essential for the virus replications.

• International Journal of Precision Engineering and Manufacturing
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• 제4권4호
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• pp.25-31
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• 2003

A computer simulation model for investigating a two-dimensional (2-D) rounding mechanism in a centerless grinding process is described. This model includes the interference phenomena and the concept of machining elasticity. Since initial contact points are used as a reference, the result of this simulation is not affected by the location of the reference circle center and the radius of the reference circle. Also, details of the machining factor are studied by using process variables (grinding wheel speed, wheel specification, workpiece speed, dressing condition, etc.). The effect of the threshold grinding force on the size of ground workpiece is investigated. For the verification of this method, simulation results are compared with the experimental work.

• 한국추진공학회:학술대회논문집
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• 한국추진공학회 2007년도 제29회 추계학술대회논문집
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• pp.89-92
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• 2007

본 연구는 원형 용기에서 배수시 배수구멍의 위치가 중심선에서 벗어난 정도에 따른 배수율과 유동장의 변화를 이해하기 위하여 배수위치의 변화에 따른 배수흐름의 특성을 연구하였다. 이 연구의 목적은 서로 다른 위치의 배수구가 와류생성을 억제하는 원리에 대해 이해는 것이다. 원형 용기의 유동장을 가시화하기 위하여 PIV기법을 사용하였다. 그리고 배수가 있을 때와 없을 때에 대해, 각각 수직방향과 수평방향에서 결과를 얻었다.

• 한국추진공학회:학술대회논문집
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• 한국추진공학회 2007년도 제28회 춘계학술대회논문집
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• pp.313-316
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• 2007

본 연구는 정사각형 용기에서 배수시 유동장의 변화를 이해하기 위하여 용기의 모서리의 반경변화에 따른 배수흐름의 특성을 연구하였다. 이 연구의 목적은 서로 다른 반지름의 모서리가 와류생성을 억제하는 원리에 대해 이해는 것이다. 사각형 용기의 유동장을 가시화하기 위하여 PIV기법을 사용하였다. 그리고 배수가 있을 때와 없을 때에 대해, 각각 수직방향과 수평방향에서 결과를 얻었다.

• 한국세라믹학회지
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• 제35권6호
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• pp.559-568
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• 1998

Studies of preparation condition and characteristics of AUC(ammonium uranyl carbonate) were carried out to optimize AUC process with different reactor sizes and precipitation methos. As results four types of precipitates with different chemical compositions and morphologies were obtained from the reaction of {{{{ {(NH }_{4 }) { }_{2 } {CO }_{3 } }} with {{{{ {UO }_{2 }( {NO }_{3 }) { }_{2 } }} solution. A phase diagram has been made and crystal structure and chemical composition of each phase have been characterized by using SEM X-ray IR and thermal analysis. It was found that ammonium uranyl carbonate {{{{ {(NH }_{4 }) { }_{4 } {UO }_{2 } {(CO }_{3 }) { }_{3 } }} with monoclinic crystal morphology could be syn-thesized when the mole ratio of in {{{{ {(NH }_{4 }) { }_{2 } {CO }_{3 }/ {UO }_{2 } {(NO }_{3 }) { }_{2 } }} in the solution was higher than 5 Also a mechanism and a precipitating condition on rounding of the AUC particle were examined in the course of the AUC pre-cipitation. The rounding of the AUC particle was possible only by external circulation using pump not by internal circulation using agitator.

• 한국염색가공학회지
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• 제13권5호
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• pp.58-58
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• 2001

This study surveys the fiber behavior in yarn formation and the physical properties of Solo-spun yarn. The specimens were made by six types of Solo-spun rollers with fixed twist multiplier. The physical properties such as yarn count, evenness, strength, and breaking elongation of these yarns were compared with the properties of ring spun yarns and analysed with the mechanism of Solo-spun yarn formation. The grooves on the surface of Solo-spun roller divide the web and interfere the twist propagation. These phenomena cause the uneven draft and the fly of fiber, so the Solo-spun yarn becomes finer than fing-spun yarn and the yarn breaking strength and elongation deteriorate, but these demerits can be improved with rounding the protruded edge of Solo-spun roller grooves.

• 한국염색가공학회지
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• 제13권5호
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• pp.346-352
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• 2001

This study surveys the fiber behavior in yam formation and the physical properties of Solo-spun yam. The specimens were made by six types of Solo-spun rollers with fixed twist multiplier. The physical properties such as yam count, evenness, strength, and breaking elongation of these yams were compared with the properties of ring spun yams and analysed with the mechanism of Solo-spun yarn formation. The grooves on the surface of Solo-spun roller divide the web and interfere the twist propagation. These phenomena cause the uneven draft and the fly of fiber, so the Solo-spun yam becomes finer than fing-spun yam and the yam breaking strength and elongation deteriorate, but these demerits can be improved with rounding the protruded edge of Solo-spun roller grooves.

• 한국지반공학회논문집
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• 제32권8호
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• pp.47-59
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• 2016

얕은 기초의 회전거동은 지진 시 상부 구조물의 지진하중을 줄이는 효과적인 방법으로 대두되고 있다. 그러나 회전거동의 메커니즘에 대한 이해부족과 항복거동으로 인한 지반변형 때문에 시공에 적용되지 못하고 있다. 본 연구에서는 원심모형실험을 이용한 수평반복하중 실험을 통해 세장비가 다른 시스템의 근입된 얕은 기초의 회전거동 특성을 평가하였다. 실험결과를 통해 기초의 회전거동으로 인한 하부지반면의 원형현상을 관찰하였으며, 이로 인해 기초의 최대 전도모멘트가 기초의 극한 모멘트 지지력과 같아지는 것을 알 수 있었다. 기초 저면에서 관측된 토압변화를 통해 항복거동으로 인한 수평거동과 회전거동의 연결(coupling)과 분리(decoupling)현상을 볼 수 있었다. 또한 기초의 회전각이 증가할수록 지반의 비선형성과 에너지 감쇠가 커짐을 알 수 있었고, 근입된 기초의 극한 모멘트 지지력이 지표면에 놓인 기초의 극한 모멘트 지지력보다 더 커지는 것을 확인하였다. 본 연구를 통해 기초의 회전거동을 이용한 내진 설계 시 보다 정확하고 적절한 기초의 극한 모멘트 지지력을 제시할 수 있을 것이라 판단된다.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제27권6호
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• pp.511-518
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• 2001

The effect of mycolactone, a recently reported apoptosis-inducing factor, was investigated in SCC15 oral squamous cell carcinoma(OSCC) cell line. Mycolactone rapidly induced cell death in OSCC cells in 2days, which was similar to that found in apoptotic cell such as detaching from culture plate and rounding-up of cells. Apoptotic cells were increased 4hrs after mycolactone treatment and more than half of cells showed apoptosis after 72hrs. Caspase 3 activation a biochemical evidence of apoptosis, was determined by Western blotting. Caspase 3 activation was started at 2hrs that lasted until 8hrs after mycolactone treatment. The expression of bcl-2 family genes was determined to explain the mechanism of apoptosis found in OSCC cells. The expressions of bad, bak, and bax (pro-apoptotic genes) and bcl-w and bcl-2 genes (anti-apoptotic genes) were not changed by mycolactone treatment. The expression of bcl-xi was decreased 8 hrs after mycolactone treatment. Mcl-1 expression was initially increased at 2 hrs which was decreased 8 hrs after mycolactone treatment. The down-regulation of these two anti-apoptotic genes might explain the mycolactone-induced apoptosis in OSCC cells. In this study, mycholactone was revealed to induce cell death in OSCC cells apoptosis and the apoptosis mechanism of OSCC cells was shown to be down-regulation of anti-apoptotic genes, bcl-xi and mcl-1. These results suggested the applicability of mycolactone for the development of an anti-cancer drug candidate by inducing apoptosis of OSCC cancer cell.