• 한국치위생학회지
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• 제23권4호
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• pp.323-331
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• 2023

Objectives: This study was conducted to confirm the relationship between role conflict, positive psychological capital, and the psychological well-being of dental hygienists and to provide data for improving professionalism by increasing the psychological well-being of dental hygienists. Methods: From May 21 to June 22, 2023, 190 data were collected through an online community of dental hygienists. The collected data were analyzed IBM SPSS program ver. 23.0 and AMOS ver. 26.0. Statistical analysis methods, convergent validity test, structural equation model analysis, and model fit were performed using independent sample t-test, one-way ANOVA, confirmatory factor analysis, structural model fit test, and path analysis. Results: The lower the role conflict of dental hygienists and the higher the positive psychological capital, the higher the psychological well-being. The lower the role conflict, the higher the positive psychological capital. However, there was no mediating effect between positive psychological capital and role conflict, as it was not statistically significant. Analysis of the total effect of role conflict and positive psychological capital on psychological well-being revealed that positive psychological capital had a greater influence on psychological well-being than role conflict. Conclusions: Psychological well-being was related to positive psychological capital and role conflict. Future efforts are needed to improve positive psychological capital and psychological well-being of dental hygienists and reduce role conflict.

• The Korean Journal of Physiology and Pharmacology
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• 제20권3호
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• pp.297-304
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• 2016

Klotho functions as a tumor suppressor predominantly expressed in renal tubular cells, the origin of clear cell renal cell carcinoma (ccRCC). Altered expression and/or activity of growth factor receptor have been implicated in ccRCC development. Although Klotho suppresses a tumor progression through growth factor receptor signaling including insulin-like growth factor-1 receptor (IGF-1R), the role of Klotho acting on IGF-1R in ccRCC and its clinical relevance remains obscure. Here, we show that Klotho is favorable prognostic factor for ccRCC and exerts tumor suppressive role for ccRCC through inhibiting IGF-1R signaling. Our data shows the following key findings. First, in tumor tissues, the level of Klotho and IGF-1R expression are low or high, respectively, compared to that of adjacent non-neoplastic parenchyma. Second, the Klotho expression is clearly low in higher grade of ccRCC and is closely associated with clinical outcomes in tumor progression. Third, Klotho suppresses IGF-1-stimulated cell proliferation and migration by inhibiting PI3K/Akt pathway. These results provide compelling evidence supporting that Klotho acting on IGF-1R signaling functions as tumor suppressor in ccRCC and suggest that Klotho is a potential carcinostatis substance for ccRCC.

• Parasites, Hosts and Diseases
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• 제60권5호
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• pp.317-325
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• 2022

Hypoxia-inducible factor-1 alpha (HIF-1α) is one of the master regulators of immune and metabolic cellular functions. HIF-1α, a transcriptional factor whose activity is closely related to oxygen levels, is a target for understanding infectious disease control. Several studies have demonstrated that HIF-1α plays an important role during the infectious process, while its role in relation to parasite virulence has not been addressed. In this work, we studied the expression levels of HIF-1α and related angiogenic vascular endothelial growth factor A (VEGF-A) in human macrophages infected with promastigotes of hypo- or hyper-virulent Leishmania major human isolates. L. major parasites readily subverted host macrophage functions for their survival and induced local oxygen consumption at the site of infection. In contrast to hypo-virulent parasites that induce high HIF-1α expression levels, hyper-virulent L. major reduced HIF-1α expression in macrophages under normoxic or hypoxic conditions, and consequently impeded the expression of VEGF-A mRNA. HIF-1α may play a key role during control of disease chronicity, severity, or outcome.

• 한국경영과학회지
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• 제5권1호
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• pp.31-38
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• 1980

The purpose of this paper is to exhibit existing replacement models and to develop new replacement models for managing equipments in large organizations, private or public. Some of the models in this paper are well known and in use, and some are not. All these models are classified, depending on main factors which play key roles on the models. One group is the models in which the economic factor plays a key role, and the other is those in which both the economic factor and the effectiveness factor play key roles.

• 대한약학회:학술대회논문집
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• 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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• pp.268.2-269
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• 2002

The recombinant histamine-releasing factor (rHRF) has been reported to induce a secretion of histamine and cytokines from inflammation-related cell types such as basophils and eosinophils. and to function as a growth factor in immune B cells. Recently. decreased expression level of HRF protein was observed in brain of patients with Alzheimer disease and Downs syndrome. suggesting a possible significant role in neurological systems. (omitted)

• 한국치위생학회지
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• 제10권5호
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• pp.887-895
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• 2010

Objectives : In this study, 233 dental hygiene students in Seoul and Gyeonggi areas were surveyed in order to provide the basic data for more effective clinical practice by investigating the stress they experience during the clinical practice and how they cope with stress; Methods : 5 areas in stress factors as environmental factor, interpersonal factor, role and activity, ideal and value, and the amount of BEPSI and 4 areas in their coping methods as problem-oriented, social support, emotion-oriented, and wishful thinking were measured by Liker 5-point scale. Results : 1. The satisfaction level of subjects on their major was the highest as 'generally satisfied (50.6%),' and their satisfaction level of clinical practice was also the highest as 'generally satisfied (32.6%).' 2. The clinical practice stress was 2.76 points on average, and their stress factors were ideal and value (3.18), environmental factor (2.98), role and activity (2,70), the amount of BEPSI (2.55), and interpersonal factor (2.37). And the way how they cope with stress were 3.29 points on average, wishful thinking (3.71), social support (3.36), problem-oriented (3.13), and emotion-oriented (2.95). 3. The clinical practice stress according to clinical training institutions showed significant differences: university dental hospitals and general hospitals (2.83), dental clinics (2.65), and dental hospitals (2.63). 4. The clinical practice stress showed a negative correlation between the satisfaction level of major and the satisfaction level of clinical practice (p<0.01), and the more satisfaction they had in their major and clinical practice, the less stress during the clinical practice. 5. In the correlation between each subordinate factor of the stress in clinical practice and how to cope with it, interpersonal factor and emotion-oriented factor, the amount of BEPSI and wishful thinking showed a positive correlation (p<0.05). Conclusions : In this study, it is necessary to develop clinical practice program that is to increase satisfaction and provide motivation in order to reduce the stress during clinical training.

• 한국산학기술학회논문지
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• 제19권11호
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• pp.38-52
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• 2018

본 연구는 유아교사의 심리적소진과 관련하여 지난 20여년 간 국내에서 연구된 석 박사 학위논문과 학술지 논문을 중심으로 심리적소진 관련요인들의 효과크기를 메타분석을 통해 검증하였다. 검증결과는 다음과 같다. 첫째, 유발요인과 억제요인들의 전체효과크기와 요인군, 하부요인, 정적 부적효과요인 모두 유의미한 큰효과크기를 나타냈다. 둘째, 유발요인군은 큰효과크기를 가진 업무상문제요인군이 중간효과크기를 가진 부정적관계요인군 보다 상대적으로 큰 효과크기를 나타냈다. 셋째, 부정적관계요인군의 하부요인 중, 큰효과크기를 가진 원장과의 부정적 관계를 제외한 모든 하부요인이 중간효과크기를 나타냈다. 넷째, 업무상문제요인군의 하부요인은 상대적으로 업무스트레스가 가장 큰 효과크기를 그 다음 역할갈등, 업무과다, 역할모호 순으로 나타났다. 다섯째, 억제요인군 별 효과크기는 상대적으로 회복탄력성요인군이 가장 큰효과크기를 그 다음 조직지원요인군, 교사효능감요인군, 사회적지지요인군, 감정노동요인군 순으로 나타났다. 여섯째, 억제요인군 중 중간효과크기를 보인 감정노동요인군의 내면적, 자연적, 표면적행동요인, 조직지원요인군의 하부요인인 조직지원요인과 교사효능감요인군의 일반교사효능감요인, 사회적지지의요인군의 직장 내 외요인, 사회적지지전체요인을 제외한 모든 요인군이 큰효과크기를 나타냈다. 일곱째, 효과요인에 있어, 직무만족, 우울, 이직의도요인은 모두 큰효과크기를 보인 것으로 나타났다. 결론적으로 본 연구는 선행된 연구들을 통합적으로 정리하여 객관적 결과를 살피기 위한 수량적 통합을 시도했다는데 의의가 있다.

• 한국보육지원학회지
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• 제15권6호
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• pp.1-19
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• 2019

Objective: This study aims to examine the level of parental perceptions and practices on parental role responsibilities for children enrolled in preschools and to verify the differences. Methods: A total of 301 parents whose children were attending preschools participated in this study. The collected data were analyzed for frequency, factor analysis, and reliability. In addition, the t-test and the Importance-Performance Analysis (IPA) were performed. Results: First, there are relatively high levels of perception and practices of parental role responsibilities. Second, parental perception of parental role responsibilities is higher than the level of actual performance. Third, although parents were highly aware of their role responsibilities, there is a great expectation of the role of preschools for the development of the social competence of children. Fourth, parents value the level of practice of role responsibilities in preschools relatively high. Conclusion/Implications: Support systems are needed to reduce the gap between parental perception and practice of their role responsibilities for children enrolled in preschools.

• 복식
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• 제60권8호
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• pp.15-28
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• 2010

The purpose of this study was to investigate how gender role attitudes affect clothing involvement and clothing consumption behaviors in young female generation by changing the traditional sex role stereotype. For the research, the survey was conducted for a month from June 15 to July 15, 2009. Data was collected a total of 368 questionnaires from 20's female university students and analyzed 301 questionnaires with SPSS 12.0. The results were as follows. First, the results of factor analysis on gender role attitudes confirmed the multifactorial theory of gender schema: modern masculinity, conservative gender roles, modern feminity based on emotion, gender role openness, and traditional feminity. Second, gender role attitude of female university students was a little conservative but flexible to accommodate masculinity and active in the emotion expression. Third, gender role attitudes had important effects on clothing involvement which was identified into 4 different factors; fashion involvement, clothing interest, performance risk, and social psychological risk. Fourth, gender role attitudes were related with clothing consumption behaviors as like shopping orientation, on-going information search behavior and brand loyalty because of needs for innovation, exhibition and differentiation. Therefore, it was concluded that not only 'androgynous' from modern feminity based on emotion but also 'masculinity' was applied to important fashion marketing strategic tools by statically affecting female consumer's clothing involvement and clothing behaviors.

• 대한가정학회지
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• 제47권8호
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• pp.87-99
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• 2009

This study aimed to explore self-esteem influencing variables such as appearance stress, sex-role identity, and depression, in order to assess self-esteem standards for children and adolescents. It also investigated mediating effects of sex-role identity and depression on self-esteem. The study subjects were 2,511 elementary students and 2,958 middle school students, selected using the Korea Adolescence Panel Data. The data collected from interviews were subjected to descriptive statistical analysis, t test, Pearson's correlation and hierarchical multiple regression. The main results were as follows: Firstly, appearance stress and depression of female students were higher than those of male students. However, sex-role identity of male students was higher than those of female students. Difference in self-esteem was not statistically significant between male and female students (P > 0.05). Secondly, appearance stress was positively correlated to sex-role identity and depression, but negatively correlated to selfesteem. Thirdly, sex-role identity and depression had a mediating affect on self-esteem. Finally, variables affecting self-esteem of children and adolescents were appearance stress, men-role identity, and depression. In addition to these variables, women-role identity was a major factor for female students.