• Journal of Distribution Science
• /
• v.13 no.11
• /
• pp.31-37
• /
• 2015

Purpose - This study is an effort to assess the role of behavioral biases in investment decision making, specifically for mutual funds, and the moderating role of the investor. Individual investment behavior is concerned with choices about purchasing various securities. However, behavioral finance disputes the concept of perfect rationality and identifies psychological factors and their impact on decision-making. Research design, data, and methodology - A survey questionnaire was designed and used to collect responses using a judgmental sampling technique from 290 investors in the Gwalior Region. Cronbach's Alpha, factor analysis, and linear regression were all used to test the influence of behavioral biases on investment decision. Results - We found that the behavioral biases have a positive impact on investment decisions. Conclusions - This study's results identified three factors influencing investor behavior(rationale, investment skills, and profit making) and four factors influencing investor decisions (profit maker, market analysis, investment plan, seller). The overall results of the study also show that there is no significant relationship between investor behavior and investment decisions by gender in the market.

• Journal of the Korea Fashion and Costume Design Association
• /
• v.13 no.3
• /
• pp.31-43
• /
• 2011

This study investigates the differences in the purchasing behavior of infant & children's wear with the features of children and consumers. This study conducted a survey on female buyers of infant & children's wear. 558 questionnaires were analyzed by using SPSS 18.0 statistic program with factor analysis, Cronbach's ${\alpha}$, cluster analysis, ANOVA, and paired t-test. The results are as follows: 1. The buyer's value was identified with 3 factors: mental achievement value, social achievement value, and pleasure value. Three types of group by values were identified: group seeking mental social achievement, group seeking social achievement, and group seeking pleasure. 2. Fashion and conformity, pleasure pursuit, and reasonable price pursuit orientations showed significant differences among the value groups. 3. A significant difference was found in the imitation of wearing role models according to sibling relationships.

• Biomolecules & Therapeutics
• /
• v.22 no.4
• /
• pp.308-313
• /
• 2014

Activator protein-1 (AP-1) is an inducible transcription factor that contributes to the generation of chronic inflammation in response to oxidative and electrophilic stress. Previous studies have demonstrated that the PI3K/Akt1 pathway plays an important role in the transcriptional regulation of AP-1 expression. Although the histone post-translational modifications (PTMs) are assumed to affect the AP-1 transcriptional regulation by the PI3K/Akt pathway, the detailed mechanisms are completely unknown. In the present study, we show that heterochromatin 1 gamma ($HP1{\gamma}$) plays a negative role in TPA-induced c-Jun and c-Fos expression. We show that TPA-induced Akt1 directly phosphorylates $HP1{\gamma}$, abrogates its suppressive function and increases the interaction between histone H3 and 14-3-$3{\varepsilon}$. Collectively, these our data illustrate that the activation of PI3K/Akt pathway may play a permissive role in the recruitment of histone readers or other coactivators on the chromatin, thereby affecting the degree of AP-1 transcription.

• Management & Information Systems Review
• /
• v.20
• /
• pp.115-135
• /
• 2007

This study explored how intrinsic and extrinsic motivation relates to achieving creativity at project work. We were interested in differences in how motivational factors relate to creativity. Using data from the 98 engineers and researchers employed by a variety of companies, principal components factor analysis with marimax rotation was performed on the data. We examined effects of the moderate variables the intrinsic and extrinsic motivation and creativity relationship. The results indicate of positive mental involvement, the time and the resource constraints relates positively to creativity in organizations and that the relationship is a simple linear one. These outcomes are significantly related to intrinsic motivation and the creativity. In additions, extrinsic motivation is related to less the creativity. Our survey findings are also consistent with other sources of knowledge on the topic. Our results suggest that there are two different role: mental involvement, time and resources constraints, both of which predict creativity, and external control and extrinsic motivations reduce to creativity.

• Korean Management Science Review
• /
• v.24 no.1
• /
• pp.45-62
• /
• 2007

We aim to explain the role of corporate's 'long-term orientation' and 'asset specificity' in the process of SCM(Supply Chain Management) practices' effect on SCM performances, with empirical study about 167 manufacturing companies ail over the country. With confirmatory factor analysis and structural equation model using AMOS program, we conclude long-term orientation and asset specificity act as 'infra-structural role', rather than 'Intermediate role', in the process of SCM practice's effect on SCM performances.

• Archives of Pharmacal Research
• /
• v.23 no.5
• /
• pp.531-534
• /
• 2000

Nitric oxide (NO), products of activated macrophages, have a great impact on the regulation of cytokine production. The role of NO in non-specific host cells is commonly accepted. On the contrary, its role as an immuno-regulatory molecule is still controversial. In this study, we have investigated the effect of NO on the production of cytokines from murine splenocytes and macrophages. S-nitroso-L-glutathione inhibited the release of both interferone-$\gamma$ and interleukin-2 produced by Th1 cells and tumor necrosis factor-$\alpha$ and interleukin-1$\beta$ produced by macrophages, but did not affect the release of interleukin-4 and interleukin-10 produced by Th2 cells. These results suggest that NO exerts a down-regulatory effect on the secretion of cytokines from Th1 cells and macrophages which are implicated in immune response. Thus, NO may have an important role as an immune-modulatory as well as effector molecule in the immune system.

• YAKHAK HOEJI
• /
• v.54 no.5
• /
• pp.410-415
• /
• 2010

We explored the role of phosphodiesterase 4 (PDE4) on parathyroid (PTH)-induced signaling in osteoblasts. PTH was shown to increase the activity of PDE, mainly PDE4, in osteoblasts, which is partly attributable to elevated PDE4B and PDE4D mRNA expression. The use of PDE4 inhibitor strengthened the PTH-induced extracellular signal-regulated kinase (ERK) and p38 MAP kinase (MAPK) activation. Furthermore, the PDE4 inhibitor stimulated PTH-induced receptor activator of nuclear factor-${\kappa}B$ ligand (RANKL) expression in osteoblasts, which in turn increased osteoclast formation. Taken together, these data suggest the negative role of PDE4 on PTH-induced signaling in osteoblasts.

• Economic and Environmental Geology
• /
• v.21 no.3
• /
• pp.319-329
• /
• 1988

As a factor which can help to understand the genesis of (mata) sedimentary and/or hydrothermal uranium depisits, an interpretation of the role of organic matter associated with uranium mineralization, was attempted with the literature published up to the end of 1986. Laboratory studies, in which diageneis and metamorphism are artificially simulated, can help to elucidate how uranium with particular organic materials are formed and destroyed. Similarly, research involving a variety of techniques is needed to characterize both the soluble organic extracts (bitumen) and the insoluble organic matter (kerogen), separated from uranium ores and associated rocks. In the presence of clay minerals and amorphous oxy-hydroxde minerals, an understanding of the role of organic matter must be prudent and may require the incorporation of multidisciplinary approach (mineralogy, inorganic geochemistry ...).

• Journal of Mechanical Science and Technology
• /
• v.20 no.6
• /
• pp.896-904
• /
• 2006

In a liquid rocket engine, the role of gas-liquid scheme injector as an acoustic resonator or absorber is studied experimentally for combustion stability by adopting linear acoustic test. The acoustic-pressure signals or responses from the chamber are monitored by acoustic amplitude. Acoustic behavior in a rocket combustor with a single injector is investigated and the acoustic-damping effect of the injector is evaluated for cold condition by the quantitative parameter of damping factor as a function of injector length. From the experimental data, it is found that the injector can play a significant role in acoustic damping when it is tuned finely. The optimum tuning-length of the injector to maximize the damping capacity is near half of a full wavelength of the first longitudinal overtone mode traveling in the injector with the acoustic frequency intended for damping in the chamber. When the injector has large diameter, the phenomenon of the mode split is observed near the optimum injector length and thereby, the acoustic-damping effect of the tuned injectors can be degraded.

• BMB Reports
• /
• v.52 no.1
• /
• pp.42-46
• /
• 2019

Cellular senescence, a process of cell proliferation arrest in response to various stressors, has been considered to be important factor in age-related disease. Identification of senescent cells in tissues is limited and the role of senescent cells is poorly understood. Recently however, several studies showed the characterization of senescent cells in various pathologic conditions and the role of senescent cells in disease progression is becoming important. Senescent cells are growth-arrested cells, however, the senescence associated secretory phenotype (SASP) of senescent cells could modify the tissues' microenvironment. Here, we discuss the progress and understanding of the role of senescent cells in tissues of pathologic conditions and discuss the development of new therapeutic paradigms, such as senescent cells-targeted therapy.