• Title/Summary/Keyword: Role Factor

Search Result 5,016, Processing Time 0.034 seconds

Metallothioneins and Oxidative Stress

  • Beattie, John H.;Trayhurn, Paul
    • Nutritional Sciences
    • /
    • v.5 no.4
    • /
    • pp.228-233
    • /
    • 2002
  • The low molecular weight zinc-binding protein metallothionein(MT) contains 32% cysteine and has been shown to efficiently scavenge hydroxyl radicals in vitro. MT expression is induced by oxidative stress and an antioxidant role for this protein has therefore been proposed. This review mainly focuses on the evidence for this role arising from studies using genetically modified animals and cells which either over- or under-express MT. Despite some considerable disparity of results in the literature, reported studies do generally support an antioxidant role. Nevertheless, oxidant stress at non-physiological treatment levels has been the preferred experimental model and there is little information about the role of MT in physiological oxidative stress. Although it is presumed that the mechanism by which MT has an antioxidant effect involves oxidation of cysteinal thiols, it is possible that zinc release from MT is in itself an important signalling factor.

A Study of Job Stress among Librarians in Public Libraries in Pusan (부산지역 공공도서관 사서들의 직무스트레스에 관한 연구)

  • 한계문
    • Journal of Korean Library and Information Science Society
    • /
    • v.30 no.4
    • /
    • pp.163-181
    • /
    • 1999
  • The purpose of this study is to confirm what the stress factors are in performing their jobs among librarians in Public libraries. The study further investigates to figure out the difference of the degree in cognition of job stress according to demographic characteristics of individuals and the impacts of the stress factors on job satisfaction. A survey was conducted for the study sending questionaires to 113 librarians working in 14 Public libraries in Pusan. The results of the study are followings: 1) Females experience higher job stress than males. 2) The younger the age, the higher the job stress. Also, the shorter the year at work, the higher the job stress. 3) The lower the license class, the higher the job stress. Also, singles than married have higher job stress. 4) In the impacts of stress factors on job satisfaction, role conflict is the most powerful factor, and then role overload, career development, role underload, role ambiguity and interpersonal relation, each in order.

  • PDF

Rhinovirus and childhood asthma: an update

  • Song, Dae Jin
    • Clinical and Experimental Pediatrics
    • /
    • v.59 no.11
    • /
    • pp.432-439
    • /
    • 2016
  • Asthma is recognized as a complex disease resulting from interactions between multiple genetic and environmental factors. Accumulating evidence suggests that respiratory viral infections in early life constitute a major environmental risk factor for the development of childhood asthma. Respiratory viral infections have also been recognized as the most common cause of asthma exacerbation. The advent of molecular diagnostics to detect respiratory viruses has provided new insights into the role of human rhinovirus (HRV) infections in the pathogenesis of asthma. However, it is still unclear whether HRV infections cause asthma or if wheezing with HRV infection is simply a predictor of childhood asthma. Recent clinical and experimental studies have identified plausible pathways by which HRV infection could cause asthma, particularly in a susceptible host, and exacerbate disease. Airway epithelial cells, the primary site of infection and replication of HRV, play a key role in these processes. Details regarding the role of genetic factors, including ORMDL3, are beginning to emerge. This review discusses recent clinical and experimental evidence for the role of HRV infection in the development and exacerbation of childhood asthma and the potential underlying mechanisms that have been proposed.

Care- and Justice-Oriented Morality : Relationships to Gender, Sex Role Identity, and Age (배려지향적 도덕성과 정의지향적 도덕성에 관한 연구 : 성과 성역할 정체감 및 연령과의 관계를 중심으로)

  • Chung, Ock Boon;Kwag, Kyung Hwa
    • Korean Journal of Child Studies
    • /
    • v.24 no.1
    • /
    • pp.1-20
    • /
    • 2003
  • This study investigated the relationships of care- and justice-oriented morality by gender and sex role identity among adolescents, and young and middle-aged adults. The subjects were 115 males and 125 females between 16 and 59 years of age. Instruments were the Ethic of Care Interview(ECI), the Korean Defining Issues Test(DIT), and the Korean Sex Role Inventory(KSRI). Age was found to be a significant factor in both care-and justice-oriented morality; that is, young and middle-aged adults demonstrated higher care-oriented morality than adolescents. While, adolescents and young adults demonstrated higher justice-oriented morality than middle-aged adults. Females exhibited higher levels of care- and justice-oriented morality. A significant interaction effect was found between gender and age for justice-oriented morality.

  • PDF

Metallothioneins and Oxidative Stress

  • Beattie, John H.;Trayhurn, Paul
    • Proceedings of the Korean Nutrition Society Conference
    • /
    • 2002.11b
    • /
    • pp.1171-1177
    • /
    • 2002
  • The low molecular weight zinc-binding protein metallothionein (MT) contains 32% cysteine and has been shown to efficiently scavenge hydroxyl radicals in vitro. MT expression is induced by oxidative stress and an antioxidant role for this protein has therefore been proposed. This review mainly focuses on the evidence for this role arising from studies using genetically modified animals and cells which either over-or under-express MT. Despite some considerable disparity of results in the literature, reported studies do generally support an antioxidant role. Nevertheless, oxidant stress at non-physiological treatment levels has been the preferred experimental model and there is little information about the role of MT in physiological oxidative stress Although it is presumed that the mechanism by which MT has an antioxidant effect involves oxidation of cysteinal thiols, it is possible that zinc release from MT is in itself an important signalling factor.

  • PDF

Metallothioneins and oxidative stress

  • Beattie, John H.;Trayhurn, Paul
    • Proceedings of the Korean Nutrition Society Conference
    • /
    • 2002.11a
    • /
    • pp.73-82
    • /
    • 2002
  • The low molecular weight zinc-binding protein metallothionein (U) contains 32% cysteine and has been shown to efficiently scavenge hydroxyl radicals in vitro. MT expression is induced by oxidative stress and an antioxidant role for this protein has therefore been proposed. This review mainly focuses on the evidence for this role arising from studies using genetically modified animals and cells which either over- or under-express MT. Despite some considerable disparity of results in the literature, reported studies do generally support an antioxidant role. Nevertheless, oxidant stress at non-physiological treatment levels has been the preferred experimental model and there is little information about the role of MT in physiological oxidative stress. Although it is presumed that the mechanism by which MT has an antioxidant effect involves oxidation of cysteinal thiols, it is possible that zinc release from MT is in itself an important signalling factor.

  • PDF

The Influences of Family Life Cycle Stage and Perception of Housework's Value on Perceived Time Pressure and Role Conflict in Housewife-teachers (교직주부에 있어서 가족생활주기와 가사노동가치인식이 시간제약지각과 역할갈등에 미치는 영향)

  • 장윤옥
    • Journal of the Korean Home Economics Association
    • /
    • v.30 no.3
    • /
    • pp.325-345
    • /
    • 1992
  • The purpose of this study was to investigated the imfluences of family life cycle stages and perception of housework's value on perceived time pressure and role conflict in housewife-teachers. The subjects of this study were 329 married women teachers that teach in junior or senior high schools in Taegu. A questionaire was used as the survey method and for the method of data analysis, factor analysis, MANOVA, and Scheff test as a post-hoc analysis. The major findings were as follows: 1) There were significant interaction effects of family life cycle stages and perception of housework's value on perceived time pressure and role conflict. 2) The main effect for family life cycle stages was significant. 3) Followup univariate F-tests revealed significant mean differences for marital, parental and homemaker's role conflict.

  • PDF

Assessment Of The Place And Role Of Personnel Management In The General Management System Of The Organization

  • Kovalenko, Yelena;Kirdan, Oleksandr;Krivonos, Anatoliy;Dobrovolska, Olena;Gutsul, Tetiana;Hromov, Sergii
    • International Journal of Computer Science & Network Security
    • /
    • v.21 no.11
    • /
    • pp.271-275
    • /
    • 2021
  • The article assesses the role of the human factor in management, analyzes the personnel policy, as well as the style and methods of management at the enterprise. The purpose of the article is to study the place and role of personnel management in the general management system of an organization. Particular tasks of the research have been solved: the place and role of personnel management in the system of general management theory have been determined; determined the place of personnel management in the system of modern sciences.

과학기술정책을 위한 국가학습조직모형

  • 오형식;신상문
    • Journal of Technology Innovation
    • /
    • v.5 no.2
    • /
    • pp.22-47
    • /
    • 1997
  • This paper suggests a model of Living & Learning Nation as a new ploicy framework. It is a combination of Living Nation and Learning Nation. Living Nation model takes the nation as a living entity composed of spirit, resource, and communication : it grows but healthy and balanced growth is needed, its organs are closely connected, it has a circulation system, the 'spirit' factor plays the central role, etc.. Learning Nation model is a national level version of learning organization concept. The model defines new perspectives on the objectives, span of means, and the role of government in S&T policy. Therefore, the model can be used to give new insights to policymakers of developing countries facing the knowledge-based economy.

  • PDF

The Role of Motivation and Appraisal Emotion in Repurchase Intention in the Performing Arts

  • Qian, Zhichen;Choi, Myeonggil
    • Journal of Information Technology Applications and Management
    • /
    • v.21 no.4
    • /
    • pp.35-50
    • /
    • 2014
  • This study examines the relationshipsbetween the antecedents of repurchase intention, with special interest in the role of appraisal emotion and recreation motivation for arts attendance. Appraisal emotion is found to have significant influence on perceived value while recreation motivation is found to directly influence appraisal emotion and perceived value. In a addition to customer satisfaction, peripheral service quality is the only factor that directly affectsrepurchase intention. Arts managers ought to focus on improving the whole experience of performing arts.