• Environmental Mutagens and Carcinogens
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• v.21 no.2
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• pp.106-112
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• 2001

In view of the effect of factor Ⅶ as a risk factor for essential hypertension, we investigated the length (I/D) polymorphism at position 323 promoter region and exon 8-Msp I RFLP of the human factor Ⅶ gene in the Korean patients with essential hypertension and normal controls. There were no significant differences in the allele, genotype and haplotype frequencies of these polymorphisms between normotensive and essential hypertensive subjects. The significant linkage disequilibrium was however, detected between two polymorphic sites. The Msp I RFLP and I/D polymorphism were also significantly associated with plasma triglyceride (TG) levels. Therefore, our results suggest that the significant association between two genetic variations in the human factor Ⅶ gene and plasma TG level may reflect the potential role of human factor Ⅶ gene as one of the genetic components for cardiovascular risk.

• BMB Reports
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• v.38 no.1
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• pp.1-8
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• 2005

Transforming growth factor-$\beta$ is a pleiotropic growth factor that has enthralled many investigators for approximately two decades. In addition to many reports that have clarified the basic mechanism of transforming growth factor-$\beta$ signal transduction, numerous laboratories have published on the clinical implication/application of transforming growth factor-$\beta$. To name a few, dysregulation of transforming growth factor-$\beta$ signaling plays a role in carcinogenesis, autoimmunity, angiogenesis, and wound healing. In this report, we will review these clinical implications of transforming growth factor-$\beta$.

• Korean Journal of Pharmacognosy
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• v.34 no.2 s.133
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• pp.150-155
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• 2003

The nuclear factor of activated T cells (NFAT) protein induce transcription of cytokine genes required for T-cell activation, including the IL-2 gene. Activation of NFAT normally plays a significant role in inducing immune response. However, excessive activation provokes immunopathological reactions including autoimmunity, transplant rejection and inflammation. Thus, several natural products were screened on the inhibitory activity against the NFAT transcription factor. Among them, Euonymus sieboldiana showed strong inhibitory activity against the NFAT transcription factor without affecting cell viability.

• The Transactions of the Korean Institute of Electrical Engineers P
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• v.67 no.3
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• pp.155-159
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• 2018

Recently, the expansion or establishment of facilities for the logistics system is increasing. Conveyor facilities play a major role in sorting and transporting logistics. Induction motors are widely used for the operation of these conveyor systems. In the logistics system, a large number of induction motors are used. These motors have a considerable distance from the power source side and have a low power factor. The installation position for the power factor compensation of the induction motor is very important. Since the voltage drop depends on the length of the line, it is an important parameter in capacitor capacity determination for power factor compensation. The capacity of the capacitors installed to compensate the power factor of the inductive load should be designed to the extent that self-excitation does not occur. In this study, we analyze the method of compensating the proper power factor considering the voltage drop and the installation position of the induction motor in the logistics system.

• Asia-Pacific Journal of Business
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• v.15 no.1
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• pp.1-14
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• 2024

Purpose - We investigate whether a potential missing pricing factor plays a significant role in the idiosyncratic volatility puzzle. Design/methodology/approach - We theoretically show how a missing pricing factor can affect the idiosyncratic volatility puzzle, and also show how to get around the problem empirically. We adopt the Fama-French five factor model for the estimation of the idiosyncratic risk and use randomly constructed portfolios as test assets. Findings - We find that a missing factor does not drive the idiosyncratic volatility puzzle. Thus, we conclude that the idiosyncratic volatility does affect the risk premium of its stock. Research implications or Originality - The Fama-French five factor model does a pretty good job in explaining the risk premiums of stocks, and it can be used to reliably estimate idiosyncratic risk of stocks.

• Journal of dental hygiene science
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• v.18 no.4
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• pp.241-251
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• 2018

This study was based on the experience of dental hygienists' role conflict, and attempted to grasp the nature of the dental hygienist role conflict factor, constituent factor and coping. Giorgi's phenomenological method was used to analyze data collected through in-depth interviews with nine dental hygienists working in a dental clinic. The analysis revealed three central meanings: task scope, role conflicts, and role conflict management style and limitations. In the first category, task scope, the range of the legal scope, and the duties performed by the dental hygienist differed slightly. The second category included role conflict due to interpersonal relationship, work, work environment, competence, and identity as a professional because of role conflict. The third category included the role conflict management style and limitations. Dental hygienists tried to solve the role conflict situation through various efforts. In the face of the reality that the conflict is not solved despite such efforts, the dental hygienists felt the limitation and chose to leave. Dental hygienists are dissatisfied with their roles because of confusion regarding professional values and lack of awareness of the professional workforce due to differences between legal scope and actual practice. Based on the results of this study, it is necessary to develop a tool to quantitatively measure the level of role conflict in dental hygienists and to conduct follow-up studies on the effects of coping strategies by role conflict situations.

• Journal of Families and Better Life
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• v.4 no.1
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• pp.71-93
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• 1986

The purpose of this study is to identify sevral variables which were assumed to have relationships with the role conflict and marital satisfaction of married working women, and to examine the relationship of the role conflict and marital satisfaction of married working women in Korea. The data for this study was obtained from the survey of the 262 married working women who reside in the city of Seoul employing questionnaire method. Such methods as frequency, percentile, factor analysis, analysis of variance (t-test, F-test), and Pearson's correlation were used for the statistical analysis for this study. The major findings of this study can be summarized as follows; 1) The role conflict level of married working women was related to variables such as age, the number of children, work time, husband's support, job satisfaction, motivation to work outside the home. 2) The overall marital satisfaction was relatively high when they have two children and the presence of household work help. Futhermore, ut was found that marital satisfaction considerably high when husband's support and job satisfaction was highly accorded. 3) The role conflict and marital satisfaction of married working women were significantly negatively correlated.

• Proceedings of the Korean Operations and Management Science Society Conference
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• 2006.11a
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• pp.346-361
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• 2006

We establish two models -'intermediate' role model and 'infra-structural' role model - to confirm what role the concepts of 'long-term orientation' and 'asset specificity' execute in the context of supply chain management practices affect on SCM performances. We confirm the model's statistical significance with empirical investigation about 167 manufacturing companies in all over the country. As a result, we find that real data fits to 'infra-structural' role model with added paths of concepts and variables rather to 'intermediate' role model. We prove these results with empirical method of confirmatory factor analysis and structural equation model with AMOS program.

• The Korean Nurse
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• v.29 no.1
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• pp.72-83
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• 1990

The purpose of this study was to identify role conflict and professional attitude of Health Center nurses for health nursing administration. The data were obtained from 151 nurses of 7 Health Centers in S from July 15 to July 22 1989 using the questiennaires which consisted of 2 scales of role conflict and profess" ional attitude. The data were analyzed by percentage, mean, t-test, ANOVA and Cronbach's $\alpha$ reliability test. The results were as follows. 1) Institutional factor had the highest mean score for the degree of role conflict. The relationship between the degree of role conflict and general characteristics was found to be statistically significant for duty position. (F=2.61, p<.05) 2) Professional educational level had the highest mean score for the professional attitude. The relationship between professional attitude and general characteristics was found to be statistically significant for educational background. (F=4.91, p<.00l), p<.00l)

• Journal of the Korean Society of Clothing and Textiles
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• v.34 no.7
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• pp.1078-1086
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• 2010

This study verifies the validity of the role-relaxed consumption scale developed by Kahle (1995b) for Korean consumers. This study also tests a model that includes consumer susceptibility to interpersonal influence along with attention to social comparison information as antecedents and their relationships. Data were gathered by surveying university students in Seoul, Korea, using convenience sampling, and 600 questionnaires were used in the statistical analysis. Correlation analysis, factor analysis, ANOVA and path analysis were conducted in order to analyze the data. It was proved that the role-relaxed consumption scale was effective for Korean consumers. A path analysis showed that consumer susceptibility to interpersonal influence and attention to social comparison information influence role-relaxed consumption.